A biofilm-like mode of growth is hypothesized to be required for the emergence of cellular life. Occurrence of common biofilm gene products in current Bacteria and Archaea is an indication for their ....

Applications are invited for an Assistant or Associate Professorship in Pathogen Genetics to be held in the Department of Genetics. We are searching for a talented individual with a track record of fu...

Für wen eignet sich eine Phagentherapie?

Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...

Researchers are racing to culture a menagerie of exotic organisms and finding lots of surprises along the way.

The word ‘microbe’ literally means 'small life.' Yet, there are species of microbes that are not microscopic and others that are not alive. So, is 'microbe' helpful shorthand or overly reductive?

Nitrogenases are enzymes that convert atmospheric N2 into ammonia, thus providing bioavailable nitrogen to living organisms. Here, Maslać et al. describe a highly thermostable, simple nitrogenase from...

The BASEL collection of phages that infect E. coli has been a valuable resource, but is limited by the peculiarities of the host strain used. This study uses a modified host to expand the collection…

Explore an exciting academic career as a Research Assistant/ Associate in Bacteria-Host Interactions. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

An international team of crystallographers determined the structure of a protein at 0.43 Ångstrom resolution, the highest ever achieved for a biological macromo

The T7 bacteriophage deactivates bacterial defence systems through T7K phosphorylation of nearly all host and phage proteins during infection.

The methyl-coenzyme M reductase subunit alpha gene (mcrA) is an important phylogenetic marker for high throughput ecological profiling of methanogenic…

Methanogenic archaea (methanogens) are key drivers of global carbon cycling and biomethane production, thriving in diverse anaerobic environments thro…

Research on the molecular biology of Archaea has long lagged behind studies of bacteria and eukaryotes. This gap was due, in part, to the initial absence of genetic tools and a general lack of interes...

The Review describes shared ancient, conserved mechanisms between human antiviral immunity and bacterial anti-phage systems, outlining universal principles of pathogen sensing, signalling and effector...

Many bacterial immune defenses transmit recognition of phage infection via the generation of diverse cyclic nucleotide second messengers. Phage have evolved to subvert this kind of immunity by sequest...

DNA glycosylases, typically used for DNA repair, can also protect bacteria against phages that would otherwise evade host immunity by incorporating modified bases into their genomes.

Systematic analysis of prokaryotic STAND NTPases — relatives of animal and plant immune receptors — uncovers diverse antiviral sensors that detect most of the core structural and replicative proteins of bacteriophages.

Using in situ cryo-electron tomography, researchers found a unique ‘arm’ domain on the small subunit of Chlamydomonas chlororibosomes. This discovery suggests that chlororibosome structure is more evo...

The bacteriophage ΦX174 was the first genome to be sequenced and the first to be chemically synthesised. Here we present a complete map of the consequences of changing every nucleotide in the ΦX174 ge...

University of California, Berkeley is hiring. Apply now!

Public microbial genomes encode an immense record of biological diversity, evolution and molecular function, but much of this information remains difficult to reuse because raw sequencing data are not...

Bacteria produce natural products to adapt to their environments, with phage interactions as major ecological and evolutionary drivers. While some nat…

Gabija acts early during phage infection, preventing phage genome circularization and replication. Phage DNA end-binding proteins prevent RecBCD loading onto linear DNA, and the absence of RecBCD lice...

An 8-year soil meta-omic time series shows how mobile genetic elements shape permafrost microbial diversity and impact a range of functions, including carbon and nutrient cycling.

Institut Pasteur and the CNRS are launching a joint call for a mid-career group leader position in Medicinal Chemistry and Chemistry for Health. We are looking for an experienced researcher (typically...