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Woodson Lab

@woodsonlab.bsky.social
167 followers 46 following 11 posts

RNA detectives on a mission to catch RNA in the act of folding & uncover how proteins helped. Run by graduate students / postdocs. Dr. Sarah Woodson’s Lab at Johns Hopkins University.

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Reposted by Woodson Lab
Aaron and the Hoskins Lab at UW Madison @uwmadisonrna.bsky.social · 31/07/2026
New from @woodsonlab.bsky.social @tjiandarzacq.bsky.social and @nilswalterlab.bsky.social www.nature.com/articles/s41...
nature.com
Exchange dynamics and kinetic control of gene regulation complexes - Nature Reviews Molecular Cell Biology
Recent evidence reveals how gene expression complexes form transient assemblies that continually exchange their subunits under kinetic control. This Perspective proposes that these dynamics form the b...
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Reposted by Woodson Lab
Johns Hopkins Arts & Sciences @jhuartssciences.bsky.social · 30/04/2026
Congratulations to historian Richard Kagan, neuroscientist Ulrich Mueller, political scientist Vesla Weaver, and biophysicist Sarah Woodson on being elected to the American Academy of Arts and Sciences. hub.jhu.edu/2026/04/30/a...
hub.jhu.edu
Four from Johns Hopkins elected to the American Academy of Arts and Sciences
Richard Kagan, Ulrich Mueller, Vesla Weaver, and Sarah Woodson among 252 individuals recognized for excellence in their fields
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Woodson Lab @woodsonlab.bsky.social · 22/04/2026
Our new paper is out! Using 19F NMR, we show that Hfq rewires the conformational dynamics of a model sRNA in a site-specific manner. Uridines at the rim undergo faster exchange (~100 μs) than those in the proximal pore (~300 μs). Congrats Elise! 🎉🎉 www.sciencedirect.com/science/arti...
sciencedirect.com
19F NMR Strategy for Probing Site-specific RNA Dynamics in Large RNA-protein Complexes: Application to the Hfq RNA Chaperone
Nuclear magnetic resonance (NMR) spectroscopy is uniquely suited to probing motions on the microsecond to millisecond timescales that underlie RNA rec…
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Woodson Lab @woodsonlab.bsky.social · 08/04/2026
🎉 We’re excited to officially kick off the ERC Synergy project, snoOPERA, with Anthony Henras, Brigitte Pertschy, and Roland Beckmann! 🎉 Bringing together labs across 3 European countries and the US, we aim to uncover hidden functions of snoRNPs in ribosome assembly. Go team! tinyurl.com/2e5r57b5
tinyurl.com
Congratulations to Anthony Henras, winner of the ERC Synergy 2025 grant!
Parmi les 66 projets sélectionnés par le Conseil européen de la recherche, Anthony Henras et l’équipe EukaRiBio (MCD-CBI) sont lauréat d’un des 13 projets du
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Woodson Lab @woodsonlab.bsky.social · 05/04/2026
🚨New paper alert! Using single molecule TIRF microscopy, we show that Nop1 destabilizes RNA structure via transient, nonspecific interactions — until specific assembly of native ribosomal complexes takes over. Congrats, Wilson! 🎉 academic.oup.com/nar/article/...
academic.oup.com
Fibrillarin/Nop1 perturbs RNA folding and assembly independently of liquid–liquid phase separation
Abstract. The liquid–liquid phase-separated environment of the eukaryotic nucleolus is proposed to benefit ribosome assembly by chaperoning rRNA folding an
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Woodson Lab @woodsonlab.bsky.social · 07/01/2026
Our recent #singlemolecule study on RNase J decay is out! Congrats, Yuan! 🎉🎉 www.sciencedirect.com/science/arti...
sciencedirect.com
Metastable Folding of Bacillus subtilis glmS Ribozyme Modulates Turnover by RNase J1
Rapid turnover of glmS mRNA in Bacillus subtilis by 5′–3′ exoribonuclease RNase J is essential for feedback regulation of glucosamine-6-phosphate (Glc…
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Woodson Lab @woodsonlab.bsky.social · 29/10/2025
This bunch of RNA lovers knows how to unwind! Enjoying A-U-tumn and apple picking 🍎🍏
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Woodson Lab @woodsonlab.bsky.social · 07/09/2025
Congratulations to Elise White @elisew00.bsky.social on winning a poster prize at the Regulating with RNA in Bacteria and Archaea meeting in Strasbourg! 🎉🎉
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Woodson Lab @woodsonlab.bsky.social · 19/07/2025
Our new paper is out in PNAS! We show that competition for binding to the Hfq matchmaker disfavors mismatched sRNA-mRNA combinations while allowing matched sRNA-mRNAs to form stable pairs. Kudos to Jorjethe Roca and Yi-Lan Chen for their fantastic work on this problem! doi.org/10.1073/pnas...
doi.org
Competition for Hfq drives kinetic selection of mRNA targets by Escherichia coli small noncoding RNAs | PNAS
Small noncoding RNAs (sRNAs) regulate gene expression in Escherichia coli bacteria in response to diverse stimuli in the environment and the host. ...
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Woodson Lab @woodsonlab.bsky.social · 10/03/2025
We had a great time at the #StandUpForScience rally in DC!
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Woodson Lab @woodsonlab.bsky.social · 24/02/2025
Congratulations to Wilson on your NAR #Breakthrough paper!
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Woodson Lab @woodsonlab.bsky.social · 21/02/2025
Hello #RNA afficionados! We’re excited to join the science community on Bluesky!
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