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Hanna Häkkinen

@hannamariahakkinen.bsky.social
71 followers 89 following 8 posts

Postdoctoral Fellow interested in cell dynamics in developing embryo. Live imaging/Mechanobiology/Early embryo at PDN in Cambridge University

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Hanna Häkkinen @hannamariahakkinen.bsky.social · 09/10/2026
How do long-lived multipotent stem cells cope with mechanical stress in vivo? We found that neural crest cells are protected from mechanical stress during migration in confined tissue environment. www.nature.com/articles/s41...
nature.com
In vivo DNA damage protection during cell migration across confining embryonic tissue environments - Nature Cell Biology
Häkkinen et al. show that zebrafish neural crest cells encounter increased tissue-scale confinement along the body axis. Despite nuclear deformation, migrating neural crest cells experience neither nu...
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Hanna Häkkinen @hannamariahakkinen.bsky.social · 27/08/2026
Excited to have my PhD work out! 💫 Huge thanks to the Ruprecht lab and especially to my wonderful co-first authors @laurafbianchi.bsky.social and @martabatetpalau.bsky.social
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Reposted by Hanna Häkkinen
Laura Bianchi @laurafbianchi.bsky.social · 27/08/2026
Ever wondered how epithelial cells clear apoptotic cells while maintaining tissue cohesion?🍝🔗 Check our new paper in which we show that E-cadherin plays a dual role in regulating basal cortex dynamics upon phagocytosis while maintaining connected tissue organization www.nature.com/articles/s41...
nature.com
De novo E-cadherin/catenin complex formation controls basal epithelial mechanics and force transmission for apoptotic cell clearance - Nature Communications
Epithelial cells remodel their shape during phagocytosis while preserving tissue cohesion. Here, authors show that the E-cadherin/catenin adhesion complex is repurposed at phagocytic contacts, where i...
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Hanna Häkkinen @hannamariahakkinen.bsky.social · 10/12/2025
Our preprint from Ruprecht lab is out there. E-cadherin/catenin complex controlling epithelial phagocytosis 🔬
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Reposted by Hanna Häkkinen
Esteban Hoijman @estebanhoijman.bsky.social · 18/06/2025
How innate immunity starts? Early embryos eliminate bacterial infections by epithelial phagocytosis, a conserved process from zebrafish to human embryos. Check our story: www.cell.com/cell-host-mi...
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Hanna Häkkinen @hannamariahakkinen.bsky.social · 30/06/2025
Really happy to have our first preprint out! 💫
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