iiinova — where your digital self keeps evolving

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RCSB Protein Data Bank @rcsbpdb.bsky.social · 22/09/2026

How X-rays and crystals revealed the true nature of things The story behind the 100-year-old discovery that continues to render Nobel Prizes.

nobelprize.org

How X-rays and crystals revealed the true nature of things - NobelPrize.org

The story behind the 100-year-old discovery that continues to render Nobel Prizes.

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Alex Guseman @alexguseman.bsky.social · 11/08/2026

Im looking for a postdoc to help with protein engineering efforts. If you know who could be a good fit send them my way! see details below:

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Reposted by Vince Luca, PhD

Abby Buchwalter @abbybuch.bsky.social · 06/08/2026

We are looking to hire a technician to join the team. This project focuses on the nuclear lamina, a cellular structure that protects and organizes the genome. Will build skills in genetic screening, genomics, and stem cell culture. Please share, please apply! aprecruit.ucsf.edu/JPF06185

aprecruit.ucsf.edu

Junior Specialist, Buchwalter Laboratory, Cardiovascular Research Institute

University of California, San Francisco is hiring. Apply now!

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I-75 Scientist @flscitriguy.bsky.social · 12/05/2026

Please share widely. The new (simpler) MIRA R35 for Early Stage Investigators (ESI) NOFO is published. First due date is 10/2/2026. files.simpler.grants.gov/opportunitie...

files.simpler.grants.gov

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Drug Monkey @drugmonkey.bsky.social · 08/04/2026

Imagine if science postdocs had NIL and a transfer portal.

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Erica D. Pratt @pratted.bsky.social · 06/03/2026

The 2025-2026 BME TT Faculty jobs list has 125 positions. #FacultySearch #BME #BMEJobsList Add a job: forms.gle/bwEzwHAEehBj... Jobs list: ericaprattlab.com/bme_jobs_list/

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Martin Pacesa @martinpacesa.bsky.social · 03/03/2026

2026 has been a remarkable year for me so far (despite the current world events): opening my lab at the University of Zurich, assembling an amazing group of people in the group, and celebrating it with a fantastic lab warming party. Figured it's also time for a small profile refresh.

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BrunetLab @brunetlab.bsky.social · 09/02/2026

Interested in the mechanisms of aging and 'rejuvenation'? Our lab at Stanford has a Research Assistant/Lab manager position open!! Apply and join our awesome team! 😎 (please share) careersearch.stanford.edu/jobs/life-sc...

careersearch.stanford.edu

Life Science Research Professional 1 in School of Medicine, Stanford, California, United States

The Brunet lab in the Department of Genetics at Stanford University (https://web.stanford.edu/group/brunet/) is seeking an independent and motivated.....

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Ben Sabari @bsabari.bsky.social · 23/01/2026

I am recruiting postdoctoral fellows to develop new research directions in the lab. We study transcriptional regulation through biomolecular condensates in development and disease, with an emphasis on first-principles and mechanistic discovery. Please repost or share with colleagues.

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Guillaume Jacquemet @guijacquemet.bsky.social · 09/01/2026

I am looking for two postdocs to join our lab - One (bio)image analyst - One cell biologist interested to work on lymphatics! The positions will open soon, be in touch!

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Derek Lowe @dereklowe.bsky.social · 29/11/2025

I believe that we are about to see a major scientific conflict play out here on BlueSky, for better or for worse. I'll weigh in on this on the blog once I'm sure that I understand everyone's positions:

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Mina Kimes @minakimes.bsky.social · 22/11/2025

Just an absolutely gutting essay by Tatiana Schlossberg, a writer, mother of two young children, and cousin of RFK Jr who is dying of leukemia. www.newyorker.com/culture/the-...

As I spent more and more of my life under the care of doctors, nurses, and researchers striving to improve the lives of others, I watched as Bobby cut nearly a half billion dollars for research into mRNA vaccines, technology that could be used against certain cancers; slashed billions in funding from the National Institutes of Health, the world's largest sponsor of medical research; and threatened to oust the panel of medical experts charged with recommending preventive cancer screenings. Hundreds of N.I.H. grants and clinical trials were cancelled, affecting thousands of patients. I worried about funding for leukemia and bone-marrow research at Memorial Sloan Kettering. I worried about the trials that were my only shot at remission. Early in my illness, when I

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Harmit Singh Malik @harmitmalik.bsky.social · 23/11/2025

Scientific journals: we don’t want you using generative AI because it makes shit up. Same journal: here is an AI summary or evaluation of this paper. This might be more useful than the actual abstract or paper that the authors freaking wrote Same journal: AI cover art which makes no sense? Oooh!

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Ernst Schmid @ernstschmid.bsky.social · 12/11/2025

Thrilled to share that the final piece of my PhD work is now on bioRxiv! biorxiv.org/content/10.1... With support from @nvidia and the @NSF, we used AlphaFold to screen 1.6M+ protein pairs, revealing thousands of potential novel PPIs. All data can be viewed at predictomes.org/hp

biorxiv.org

Proteome-wide in silico screening for human protein-protein interactions

Protein-protein interactions (PPIs) drive virtually all biological processes, yet most PPIs have not been identified and even more remain structurally unresolved. We developed a two-step computational...

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Reposted by Vince Luca, PhD

Mara Duncan @mcduncanlab.bsky.social · 11/11/2025

Biological Chemistry's position is still taking applications. UM is a great place to be a PI, I'd love to see a new membrane biology or lipids expert join our community. This is open for new and established investigators.

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Reposted by Vince Luca, PhD

John Ngo @johntngo.bsky.social · 10/11/2025

Computrs usd a rstrictd alphabt to dsign protins that fold & “mak sns.”

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Julien Sage @juliensage.bsky.social · 10/11/2025

Excited to share our new review on our current understanding of small cell lung cancer (SCLC) heterogeneity and plasticity, led by Gina Duronio in the lab: www.tandfonline.com/doi/full/10....

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Reposted by Vince Luca, PhD

boehninglab @boehninglab.com · 07/11/2025

We are hiring an immunologist. This is a hard money position. We have a very robust research infrastructure. Rowan is rapidly growing, with 20,000+ undergrads, two med schools, and a vet school. Contact me for more details. jobs.rowan.edu/en-us/job/50...

jobs.rowan.edu

Rowan HR - Details - Open-Rank Tenured/Tenure-Track Faculty, Immunology, Department of Biomedical Sciences (CMSRU)Job Postings | Human Resources | Rowan University

Rowan University is a Carnegie-classified national doctoral research institution dedicated to excellence in undergraduate and graduate education.

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David Breslow Lab @davidbreslowlab.bsky.social · 30/10/2025

Excited to share our latest work on a new cilia disassembly pathway and a link between this pathway and the neurological disorder focal cortical dysplasia: www.science.org/doi/10.1126/... Brief summary: we used a genome-wide CRISPRa GOF screen to identify negative regulators of ciliary signaling...

science.org

A CRISPR activation screen reveals a cilia disassembly pathway mutated in focal cortical dysplasia

A gain-of-function screen uncovers a cilia disassembly pathway linked to genes somatically mutated in neurodevelopmental disease.

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Ben Saunders @bensaunders.bsky.social · 30/10/2025

ATTN: Two faculty positions are available in my department (neuroscience) at the University of Minnesota. This is a general search with no topic focus. November 20th application deadline. Apply here: hr.umn.edu/jobs/Find-Job Assistant Prof job code: 364920 Associate/Full Prof job code: 364921

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Department of Chemistry, Stanford University @stanfordchemistry.bsky.social · 21/10/2025

This year’s Merck-Banyu Lectureship Award winner is Professor Koji Kubota from Hokkaido University. We are thrilled to welcome him to Stanford Chemistry on Thursday, October 23rd where he will give an exciting lecture on "Exploring Synthetic Mechanochemistry." chemistry.stanford.edu/events/merck...

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saligramalab.bsky.social @saligramalab.bsky.social · 14/10/2025

For the #lovers of #TCRs -we are looking for #postdocs with interest in #functional and #mutational studies -dare to express 700 #self #antigen #specific #TCRs and #study them in #depth!!!!

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Eric Topol @erictopol.bsky.social · 09/10/2025

Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years? A 30-year long mystery unraveled @ScienceMagazine today! Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation www.science.org/doi/10.1126/...

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Daniel V. Oliveira @danielvoliveira.bsky.social · 06/10/2025

If you’re around at the #NotchMeetingXIII poster session today, come by to check out Poster #9! 🧬✨ @anna_frontino will be there presenting our shared work on how Jagged1 variants shape liver vascular and biliary development. Stop by to say hi and chat Notch!

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Denis Wirtz @deniswirtz.bsky.social · 05/10/2025

CAR T therapy has seen great effectiveness in liquid tumors, but little in solid tumors (e.g. ovarian cancer). Here we developed hyper-migratory CAR TV cells to infiltrate en masse ovarian tumors. (Left: control CAR T cells; right CAR TV cells). Read this here: www.biorxiv.org/content/10.1...

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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 18/09/2025

I've been watching as NIGMS works their tails off to get R35 awards out the door before the end of the FY on 30 Sept. They all look great but this one really grabbed my attention. It's about long "noncoding" (lnc) RNA's. Only, this one *does* encode peptides… reporter.nih.gov/project-deta...

reporter.nih.gov

RePORT ⟩ RePORTER

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Antoni Wrobel @agwrobel.bsky.social · 08/09/2025

Dear scientific community, I am looking for two postdoctoral structural biologists to join my group at the Department of Biochemistry, University of Oxford. my.corehr.com/pls/uoxrecru... my.corehr.com/pls/uoxrecru...

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Research Professional News @resprofnews.bsky.social · 26/08/2025

University efficiency drives may have opposite effect, study finds. The administrative burden in Australian universities is most keenly felt by teaching and research staff, according to a study from the University of Melbourne’s faculty of education. www.researchprofessionalnews.com/rr-news-aust...

researchprofessionalnews.com

University efficiency drives may have opposite effect, study finds - Research Professional News

Teaching and research staff say reforms mean more red tape for them, Australian survey reports

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Vince Luca, PhD @thelucalab.bsky.social · 27/08/2025

Bindcraft is awesome! If you haven’t already seen the preprint check out the final pub here. We’ve had nearly 100% success using it for the targets we’ve attempted.

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Reposted by Vince Luca, PhD

Martin Pacesa @martinpacesa.bsky.social · 27/08/2025

Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, Christian, @sokrypton.org, Bruno and many other amazing lab members and collaborators. www.nature.com/articles/s41...

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derek guy @dieworkwear.bsky.social · 23/05/2025

Am I crazy or did we just have a convo about how we can't fund cancer research?

Senator Marsha Blackburn tweets: "We're going to build a big, beautiful Golden Dome."

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Reposted by Vince Luca, PhD

Senator Bernie Sanders @sanders.senate.gov · 16/05/2025

Donald Trump cut funding for cancer research by 31% in the first three months of his term. This is an attack on every American family who has loved someone with cancer.

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Tom Ellis @proftomellis.bsky.social · 02/05/2025

My dept in London at Imperial (Bioengineering) is recruiting a group leader at Professor level 🧑‍🎓 Please RT. It's a great place with world-class expertise in all sorts of biomedical & biological engineering topics like synthetic biology. It's also not in the USA. www.imperial.ac.uk/jobs/search-...

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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 30/04/2025

"I would not have dared to dream that metastatic melanoma would become a treatable disease in my lifetime. Yet here we are today, with 43% of people diagnosed with metastatic melanoma living 10 years or more, due to treatments that we broadly refer to as cancer immunotherapy." Barry P. Sleckman, UAB

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Flora Rutaganira @frutag33.bsky.social · 21/04/2025

Hello Community! Are you a postdoc/grad student preparing to launch a faculty search? Do you have a track record of excellence in research, leadership, mentorship & community engagement? Apply to the 2025 Next Generation Faculty Symposium: www.berkeleystanfordnextgensymposium.com! Pls repost! (1/3)

Flyer for the 2025 Next Generation Faculty Symposium (including QR code in top right corner). This symposium highlights the work of exceptional early-career scientists in the broad field of quantitative biological and biomedical sciences, with a track record of excellence in research, leadership, mentorship, and community engagement. These early career scientists are preparing to launch a faculty search. Applications are due May 30th, 2025.

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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 26/04/2025

Huge opportunity for postdocs gearing up for an academic job search, hosted by @stanford-chemh.bsky.social @berkeleymcb.bsky.social and UCSF!

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Daniel Convissor @danielconvissor.bsky.social · 19/04/2025

Actually, flip the headline. It's really "How the Federal Government Became so Dependent on Universities." These competitively awarded, peer reviewed research grants produce tremendous returns on investment. New tech, health, science that benefit all people & businesses in the USA & world.

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Xantha Karp @xanthakarp.bsky.social · 11/04/2025

Congratulations to Iva Greenwald and Gary Struhl for the Gairdner Award for their work on Notch!! It’s so lovely to have some good news in these difficult times. zuckermaninstitute.columbia.edu/columbia-gai...

zuckermaninstitute.columbia.edu

Columbia Scientists Win International Award for Fundamental Research that Advances Understanding of Biology and Disease

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Chrystal Starbird @drstarbird.bsky.social · 24/03/2025

There is still time to apply for this funded postdoc position! 👇🏾Applicants must apply using the link in the original post below to be considered. Please apply if interested!

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Gita Abhiraman @gitaabhiraman.bsky.social · 12/03/2025

Excited to share this work from the Garcia Lab out today in @naturecomms.bsky.social! We engineer "cytokine adaptors", molecular immune switches that simultaneously block a target cytokine while inducing local activation of alternative cytokine receptors. rdcu.be/ec7GS

rdcu.be

Redirecting immune signaling with cytokine adaptors

Nature Communications - Cytokines are immune signaling molecules that are frequently dysregulated in disease. Here, the authors create engineered cytokine ‘adaptors,’ molecular switches...

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Vince Luca, PhD @thelucalab.bsky.social · 10/03/2025

New lab tradition alert🚨 Elliot poses with his honorary PhD sword! We got the idea when I was a thesis opponent in Finland, and it was too cool not to implement it here… Congrats again, Elliot!

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Jeremy Berg @jeremymberg.bsky.social · 05/03/2025

"NIH" is still "working" on this. They are either just plain stalling or developing "guidance" for the councils to align with administration priorities.

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Vince Luca, PhD @thelucalab.bsky.social · 05/03/2025

My first PhD student, Elliot Medina, successfully defended his thesis today! And as an added bonus, he got a job offer during his Q&A session! Elliot is an absolute wizard of a structural biologist & protein engineer. I could not have been more fortunate to have him as employee #1 in my lab.

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Jim Van Deventer @vandeventerjim.bsky.social · 28/02/2025

This quote is all I have to go on: "CSR can now begin sending forward Federal Register notices (FRNs) incrementally to begin the resumption of SRG meetings." No idea about council meetings. In any case, sending you courage (and trying to figure out how to be courageous myself!).

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Mike Thompson @thompson-lab.bsky.social · 28/02/2025

Last day to register and submit your abstract for the West Coast Structural Biology Workshop. Don't miss out!! wcsbw2025.macromolecules.xyz

wcsbw2025.macromolecules.xyz

WCSBW 2025

2025 West Coast Structural Biology Workshop

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Jeff Mugridge @jeffmugridge.bsky.social · 27/02/2025

I wrote an opinion piece for my hometown newspaper in Central NY about attacks on NIH/NSF/research and why this harms not just US science but local jobs and economies. Thanks @sciencehomecoming.bsky.social for sparking these efforts! I encourage others to join in! www.syracuse.com/opinion/2025...

syracuse.com

Protect science funding driving innovation, investment in Syracuse (Guest Opinion by Jeffrey Mugridge)

Severe cuts to budgets and staff threaten to undermine the next generation of American scientists, writes professor who discovered his love of science as a Liverpool High student.

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