Reposted by Xantha KarpMark Peifer (He, him) @peiferlabunc.bsky.social · 28/09/2026Are you looking for a postdoc exploring the cell biology of development, defining how cells change shape and move? Do you want to develop a research program & teaching skills preparing you for a position at a college or small University? Our new NIH grant will support those goals 1/n Please share 5104102
Reposted by Xantha KarpmicroPublication Biology @micropub7n.bsky.social · 25/09/2026The CCT chaperonin is a context-dependent regulator of RNA-binding protein phase transitions #micropublication #biology #data #caltechlibrary #Celegans #PhenotypeData #NewFinding micropublication.org/journals/biolo… 042
Reposted by Xantha KarpJohn Greally @greally.bsky.social · 23/09/2026Tim Bestor has left us. This obituary captures him well — you always had to be at your intellectual peak with him, while his trainees always spoke highly of their experiences. He made a massive contribution to epigenetics, a giant in our field. www.genetics.cuimc.columbia.edu/news/memoria...genetics.cuimc.columbia.eduIn memoriam of Professor Timothy H. BestorIn memoriam: Professor Timothy H. Bestor 1952-2026 23722
Reposted by Xantha KarpNick Burton @nickburton.bsky.social · 18/09/2026Very excited to put out this new preprint from the lab that represents our 3rd paper now in the lab's move into the field of identifying bioactive molecules in bacteria using C. elegans and studying how they regulate animal physiology. Really excited about this space- www.biorxiv.org/content/10.6...biorxiv.org 4146
Reposted by Xantha KarpmicroPublication Biology @micropub7n.bsky.social · 14/09/2026Call for Volunteers: C. elegans Managing Editors for microPublication Biology micropublication.org/news/0f62741... 059
Reposted by Xantha KarpGenetics Society of America @genetics-gsa.bsky.social · 08/09/2026🪱 A behavior analysis in #Celegans highlights that the change in reproductive strategies to increase mating following dauer diapause requires sexually dimorphic changes in behavior. Find out more in #G3journal 🔗 buff.ly/Zgi3QXQ 022
Reposted by Xantha KarpMax Kozlov @maxkozlov.bsky.social · 04/09/2026Under pressure, the DOD just released the text of its secret 10-year agreement with the NIH. Here are the biggest revelations from the document 🧵 13590343
Reposted by Xantha KarpMadScientist @mads100tist.bsky.social · 29/08/2026Do you work with microscopy images and segment to quantify or track? Do you study cell biology? development? Gather round! Let me tell you about FOCUS-3D, a segmentation algorithm that is fast, accurate and can be used on any model. We used it here to study zebrafish development. 🧪 (thread)biorxiv.orgFOCUS‑3D: Robust, generalizable volumetric cell segmentation for three‑dimensional fluorescence microscopyUnderstanding how cells establish spatial organization within tissues is a fundamental question in life sciences. While modern three-dimensional fluorescence microscopy captures large-volume tissue ar... 1525183
Reposted by Xantha KarpMary Munson @marymunson4.bsky.social · 26/08/2026Structural biology postdoctoral position open in my lab--apply now! For more information about the lab, see www.umassmed.edu/munsonlab/. Interested candidates should apply through the University of Massachusetts Chan Medical School jobs portal (www.ummsjobs.com/job/11668/).umassmed.eduMunson Lab | Home | BMB | UMass Chan Medical SchoolThe Munson Lab researches the mechanistic basis for the regulation of spatial and temporal specificity in membrane trafficking in the Biochemistry & Molecular Biotechnology Department at UMass Chan Me... 02644
Reposted by Xantha KarpDrug Monkey @drugmonkey.bsky.social · 18/08/2026NIH RFI on plans to stop using percentiles to select grants for funding drugmonkey.wordpress.com/2026/08/18/n...drugmonkey.wordpress.comNIH RFI on plans to stop using percentiles to select grants for fundingThe NIH issued NOT-OD-26-088 Request for Information (RFI) on Proposed Changes to Reporting Outcomes from NIH Peer Review on 8/14/2026. It proposes a radical upheaval of the way that NIH’s Pr… 42614
Reposted by Xantha KarpMadScientist @mads100tist.bsky.social · 06/08/2026Dearest all: I am looking for a queer-owned store that would sell rolls of stickers (or something as in tens of them) with pronouns for handing them out upon registration at the German Fish Meeting. Any pointer/s and RT appreciated! 🧪🐟 73231
Reposted by Xantha KarpGrosshans Lab @labgrosshans.bsky.social · 05/08/2026RNA-binding proteins (RBPs) often bind numerous transcripts - but do they act through a network effect? Our new paper in @plosbiology.org shows that the highly conserved LIN28 RBP controls developmental timing in C. elegans larvae through only two targets. doi.org/10.1371/jour... 1/n 22811
Reposted by Xantha KarpJavier Apfeld @javierapfeld.bsky.social · 05/08/2026Mentee sign-ups are open for the 2026-2027 C. elegans Community Mentor Match Program! Choose: - One-to-one mentoring with an experienced mentor - A peer-mentoring group with people at your career stage Or sign up for both, it takes just 2-5 minutes. And please spread the word! 🧵forms.gleMentee sign-up for the C. elegans Community Mentor Match programThe 2026 cycle of the C. elegans Community Mentor Match is open to graduate students, postdocs, and faculty at any career stage. ⏱️ This form takes only 2–5 minutes to complete depending on your choic... 21015
Reposted by Xantha KarpGenetics Society of America @genetics-gsa.bsky.social · 03/08/2026How can a tiny worm shape a scientific career? Join 2026 GSA Mentorship Award recipient @irinakitop.bsky.social of @fredhutch.org on August 20 at 1:00 p.m. EDT as she shares how C. elegans has guided discoveries, collaborations, and approaches to mentorship. 🔗https://buff.ly/iUmQCCQ 0188
Xantha Karp @xanthakarp.bsky.social · 22/07/2026How do developmental pathways adjust when harsh environments cause delays or interruptions in development? 🧪🧬 C. elegans can enter the stress-resistant and developmentally arrested dauer diapause stage. Progenitor cells actively maintain multipotency during dauer. 🧵 281
Reposted by Xantha KarpMaureen Barr @barrlab.bsky.social · 14/07/2026Really excited about our new paper. The 2nd author Carlos Nava Cruz started as an UG, was supported by an diversity NIH supplement, & is completing his masters. C. elegans model for functional analysis of conserved ADPKD variants in cilia, EVs, & signaling academic.oup.com/genetics/art...academic.oup.comA C. elegans model for functional analysis of conserved ADPKD variants in cilia, extracellular vesicles, and sensory signalingAbstract. Interpreting the pathogenic significance of missense variants in human disease gene candidates remains a major challenge in precision medicine. A 43310
Reposted by Xantha KarpNeedhi Bhalla 💅🏽 @needhibhalla.bsky.social · 14/07/2026a key reason why generative AI might not be able to replace biologists. Other biologists might refer to metis as intuition, the deep knowledge that comes from knowing one's system, so that you know when and when not to follow an experimental lead: journals.biologists.com/jcs/article/...journals.biologists.comThe importance of indifference in scientific researchSummary: Martin Schwartz suggests a different approach to scientific ethics that looks at the scientific process from the inside. 0238
Reposted by Xantha KarpJorge Iván Castillo-Quan @castilloquan-ji.bsky.social · 13/07/2026Excited to share that in mid-August I'll be opening the Castillo–Quan Laboratory (CORA Lab) as a tenure-track Assistant Professor at Ohio University! We study stress responses, homeostasis & healthy aging in C. elegans. Recruiting two PhD students for Aug 2027. Join us @ohiouniversity.bsky.social! 3124
Reposted by Xantha KarpNeedhi Bhalla 💅🏽 @needhibhalla.bsky.social · 12/07/2026After submitting your comment: CONTACT YOUR CONGRESSIONAL REPRESENTATIVES “Congress can override the rule through the appropriations process. They can write into statute a requirement to follow peer review and best scientific practices. In this way, Congress can stop the attacks on science.” 13630
Reposted by Xantha KarpMDI Biological Laboratory @mdibl.org · 10/07/2026Job opportunity for a #postdoc in the Updike Lab: The Dustin Updike Lab at MDI Bio Lab uses #Celegans to investigate gene function in the germline, with a particular focus on epigenetic mechanisms that maintain germ cell identity. Apply: ow.ly/Mg6i50Zl5rN #sciencejobs #STEMjobs #postdocjob 075
Reposted by Xantha KarpGenetics Society of America @genetics-gsa.bsky.social · 10/07/2026🪱 A new mutant analysis reveals the functions of miRNA-producing small RNA pathway in #Celegans male fertility, sperm production, and gonad morphology. Learn more in #G3journal 🔗 buff.ly/Sc8hDzk 032
Reposted by Xantha KarpJavier Apfeld @javierapfeld.bsky.social · 06/07/2026Worm friends 🪱 We need your video! Our C. elegans Mentor Match website has short videos from mentors and mentees sharing their experiences. Check it out, record your own video, and please share!padlet.comC. elegans Mentor Match TestimonialsMade with Padlet 065
Reposted by Xantha KarpKatja Kasimatis @katjakasimatis.bsky.social · 03/07/2026First paper from the Kasimatis Lab is now online! We investigate of the maintenance of mate plugging in C. elegans along with its function www.biorxiv.org/content/10.6...biorxiv.orgA Male Expressed Copulatory Plug Increases Female Fertility in Caenorhabditis NematodesThe genomes of self-fertilizing hermaphrodites offer a unique opportunity to probe why some genes with sex-specific functions are lost while others are maintained. In the androdiecious species, Caenor... 12411
Reposted by Xantha KarpJavier Apfeld @javierapfeld.bsky.social · 01/07/2026Do you want to support the next generation of C. elegans researchers? We are looking for mentors with C. elegans experience, including postdocs, faculty, and scientists outside academia, to share their knowledge and career advice with early career researchers. Sign up to become a mentor!forms.gleMentor sign-up for the C. elegans Community Mentor Match program - 2026Thanks for volunteering to be a Mentor! The 2026 cycle of the C. elegans Community Mentor Match is open to graduate students, postdocs and faculty at any career stage. This survey collects information... 1816
Reposted by Xantha KarpIrini Topalidou @irinakitop.bsky.social · 24/06/2026Hey C. elegans friends! What's your preferred method for cell-specific knockout or knockdown? Would love any paper recommendations too! Thank you!!! 556
Reposted by Xantha KarpZihao (John) Li @zihaojohnli.bsky.social · 24/06/2026For #Celegans researchers: want to capture better worm images? Our new paper explains how light scatters from the worm body and reveals practical strategies for improving imaging quality. Check out our new paper in iScience @cp-iscience.bsky.social: www.cell.com/iscience/ful... 0124
Reposted by Xantha KarpMark Peifer (He, him) @peiferlabunc.bsky.social · 23/06/2026This is the biggest threat to American science thus far, and that says a lot, I wrote--the template makes it easy to personalize. 🧪 12413
Xantha Karp @xanthakarp.bsky.social · 14/06/2026The Central Michigan University contingent had a fantastic time at #wormtopicmeeting2026 in Madison! C. elegans meetings are the best 0394
Reposted by Xantha KarpColette Delawalla, PhD @cdelawalla.bsky.social · 01/06/2026Best time to start Standing Up for Science was years ago. Second best time is NOW. 📣Leave public comment ☎️Contact Congress 🚨Register for the @standupforscience.net Emergency Science Meeting tomorrow at 4pm et ONE STOP SHOP: fight2win.standupforscience.netfight2win.standupforscience.netStand up for ScienceStand up for Science 010046
Reposted by Xantha KarpThiago Carvalho @cyrilpedia.bsky.social · 31/05/2026'If a control experiment fails, does that mean that the entire experiment is poorly designed and you must restart from scratch? Often, yes— but not always. I present five examples where failed control experiments triggered entirely new fields of research.' link.springer.com/article/10.1...link.springer.comThe controls that got out of control - EMBO ReportsEMBO Reports - When experimental controls go wrong, it does not necessarily mean your experiment is flawed. It might well be the first sign of something unexpected. 07540
Reposted by Xantha KarpColette Delawalla, PhD @cdelawalla.bsky.social · 29/05/2026🚨The OMB rule will be the end of science as we know it. MARK YOU CALENDAR for the @standupforscience.net EMERGENCY SCIENCE MEETING June 2nd, 4pm et. We will be giving an overview & assigning EVERY SCIENTIST IN AMERICA their marching orders. REGISTER: events.standupforscience.net/stand-up-for...events.standupforscience.netEmergency Science Meeting by Stand Up for Science[discussing OMB-2026-0034?] 16839
Reposted by Xantha KarpJavier Apfeld @javierapfeld.bsky.social · 28/05/2026Hey worm people, if you have been a mentor or mentee in the C. elegans Mentor Match program, can you record a short video with advice to future participants? So far we have 3 videos, it would be nice to get to >20. Click on the link below to help us out!padlet.comC. elegans Mentor Match TestimonialsMade with Padlet 031
Reposted by Xantha KarpJeremy Berg @jeremymberg.bsky.social · 27/05/2026I heard from several sources yesterday that NIH is planning to release a Request for Information (RFI) that apparently will include this: Scores and percentiles for NIH grant applications will not be shared with applicants although they will be provided to NIH program officers and staff. 1/3static.klipy.comHuh KermitALT: Huh Kermit 14159103
Reposted by Xantha KarpGenetics Society of America @genetics-gsa.bsky.social · 26/05/2026👉️ Are you an undergraduate student interested in genetics? 👉 Do you want to learn how to read a research paper properly? 🪱 Read the #WormBase article in the May issue of #GENETICS, which provides a step-wise guide on understanding a #Celegans study. 🔗 buff.ly/fUkhQum 033
Reposted by Xantha KarpJavier Apfeld @javierapfeld.bsky.social · 27/05/2026Worm friends, we need your help! For the next C. elegans Mentor Match cycle, we’re gathering testimonials from past mentors and mentees. One of our biggest challenges is recruiting new mentees, and hearing directly from past participants could really help. Please record a short video, and share!padlet.comC. elegans Mentor Match TestimonialsMade with Padlet 01518
Reposted by Xantha KarpZebrafish Rock! @zebrafishrock.bsky.social · 25/05/2026Dearest shoalmates: Please consider posting a comment to the NIH regarding the Strategic Plan that includes reducing funding for animal research. Responses from the research community are currently greatly underrepresented compared w/ advocacy groups opposing animal experimentation. 🔗 below ⬇️ 1/2 22927
Reposted by Xantha KarpBuck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 09/05/2026Opening for a #postdocjob in modeling of #genetics of host- #microbiome interactions in #Celegans at @bcmhouston.bsky.social — take a look here: www.linkedin.com/jobs/view/44... Questions or apply via cover letter, CV, and references to bucks [at] bcm.edu . Hiring ASAP! #microsky #jobs 🦠🪱🧬linkedin.comBaylor College of Medicine hiring Postdoctoral Fellow in Genetics of Host-Microbiome Interactions in Houston, TX | LinkedInPosted 7:15:27 PM. Company DescriptionBaylor College of Medicine, located in the Texas Medical Center in Houston, is…See this and similar jobs on LinkedIn. 11221
Reposted by Xantha KarpDenis Wirtz @deniswirtz.bsky.social · 09/05/2026Download our updated database of postdoc fellowships from different foundations and agencies. We identified 275 fellowships. For each entry, we provide description of the fellowship, focus, amount, deadline, eligibility, etc. Download this database here: research.jhu.edu/rdt/funding-... 04326
Reposted by Xantha KarpNick Burton @nickburton.bsky.social · 07/05/2026As one of the postdocs in my lab will be leaving to take a faculty position soon I will likely be placing a new ad in the coming week for someone with experience mapping C. elegans mutants from screens or doing bacterial genetics. If anyone knows/has candidates #Celegans #worms #bacteria #genetics 089
Reposted by Xantha KarpJonathan Pettitt @genotripe.bsky.social · 04/05/2026New paper from the lab. "Cap-adjacent 2′-O-ribose methylation of RNA in C. elegans is required for postembryonic growth and germline development in the presence of the decapping exonuclease EOL-1". This thread explains the background to the paper and our key findings. doi.org/10.1093/nar/... 1/15doi.orgCap-adjacent 2′-O-ribose methylation of RNA in C. elegans is required for postembryonic growth and germline development in the presence of the decapping exonuclease EOL-1Abstract. Cap-adjacent 2′-O-ribose methylation (cOMe) of the first two transcribed nucleotides of RNA polymerase II transcripts is a conserved feature in m 3188
Xantha Karp @xanthakarp.bsky.social · 23/04/2026The Karp lab had a fantastic day at the Midwest C. elegans meeting last week with 6 undergrads and 3 grad students presenting. Thanks to @nickburton.bsky.social and the other organizers for all their work. It’s such a pleasure to get together and talk about science. 040
Reposted by Xantha KarpDan Richards @dan-m-richards.bsky.social · 16/04/2026Normally non-toxic bacteria, when induced to produce the bioplastic PHB, kill C. elegans! PHB has been in the microbiology text books for over a century — in this new study I co-authored with Gabrielle Giese in the Walhout lab we show this bioplastic is also relevant for host-microbe interactions! 1123
Reposted by Xantha KarpNeedhi Bhalla 💅🏽 @needhibhalla.bsky.social · 15/04/2026I'm excited to tell you about the most recent preprint in my lab, demonstrating that a conserved spindle matrix protein, NPP-21/TPR, is required for the stronger checkpoint in germline cells during embryogenesis in C. elegans 76421
Reposted by Xantha KarpGenetics Society of America @genetics-gsa.bsky.social · 01/04/2026⚒️ NEW TOOLBOX for #Celegans researchers 🪱 Theresa Gibney and Ariel Pani developed a method that allows for a standardized workflow to generate N-terminal and internal tags in any background and without the need for genetic balancers. Paper in #GENETICS:🔗 buff.ly/wXMml3x 0114
Reposted by Xantha KarpSavage-Dunn lab @cswormlab.bsky.social · 27/03/2026It’s great to see our latest microPublication go live! Four undergraduate researchers worked with grad student Kat Yamamoto to demonstrate a correlation between fat storage and survival of #Celegans on pathogenic bacteria! Congrats Alan, Grace, Tiffany, and Daniel! #undergradinthelab #proudPI 4166
Reposted by Xantha KarpMark Peifer (He, him) @peiferlabunc.bsky.social · 16/03/2026Science professors and educators all have a role in combating this eugenics resurgence www.sciencedirect.com/science/arti... 312952
Reposted by Xantha KarpMaureen Barr @barrlab.bsky.social · 16/03/2026New preprint! An ECM gene acts cell non-autonomously from neighbor neurons to regulate ciliary function, protein localization, extracellular vesicle shedding, and ultrastructure @katiejacobs.bsky.social is the lead in another great collaboration w/ David Hall www.biorxiv.org/content/10.6... 44814
Reposted by Xantha KarpMax Heiman @heiman.bsky.social · 13/03/2026NYT feature on their website's front page about our local C. elegans colleague Will Mair and NIH funding www.nytimes.com/2026/03/13/u...nytimes.comHis Harvard Lab Was Thriving. Then Came the Cuts. 15421
Reposted by Xantha KarpAntebi Lab @antebilab.bsky.social · 26/02/20261/4 Our preprint “Modulation of the RNase P/MRP complex and mitochondrial ribosome enhances cytosolic ribosome coordination and sustains longevity” is now live @biorxivpreprint.bsky.social 📄 #agingbiology #ribosome 👉https://www.biorxiv.org/content/10.64898/2026.02.23.707525v1 142
Reposted by Xantha KarpTeresa Lee @snickclunk.bsky.social · 23/02/2026🪱Worm-friends! Join us this summer in Madison for the C. elegans topic meeting(s) - MAPSS *and* DevCell 🪱 Early birds get the you-know-what, and the early registration deadline is THIS FRI: conferences.union.wisc.edu/ceaging/ It's buy-one-get-one, and who out there doesn't love a deal?? 🙌conferences.union.wisc.eduAging, Metabolism, Stress, Pathogenesis and Small RNAs in C. elegans | Hosted By Wisconsin Union Conference Services 064