Sign in

Byron Lab

@thebyronlab.bsky.social
1.4K followers 1.2K following 30 posts

🔬 Cell adhesion networks lab 🥼 A new cell systems biology team 📍 University of Manchester, UK 🔗 linktr.ee/TheByronLab

PostsRepliesMedia
Byron Lab @thebyronlab.bsky.social · 18/09/2026
Registration is open for the 8th Workshop IRE on Translational Oncology, focussed on the extracellular matrix in cancer! Regina Elena National Cancer Institute, Rome, 19–20 October 2026. Registration is free of charge and you can sign up at www.mitcongressi.it/index.php?la...
The 8th Workshop IRE on Translational Oncology. Rome, 19-20 October 2026
100
Reposted by Byron Lab
American Statistical Association History of Statistics @hos-asa.bsky.social · 21/07/2026
Few statisticians know that Frank Yates, pioneer of experimental design, is responsible for the annoying practice of indicating 3 tiers of statistical significance by stars (*p ≤ 0.05, **p ≤0.01, ***p ≤ 0.001). He soon regretted it and “vehemently opposed its unthinking use”. And here we are.
112954
Byron Lab @thebyronlab.bsky.social · 22/07/2026
Two proud graduations from our lab @manchester.ac.uk this week! 🎓 Huge congratulations to our MSci and BSc Medical Biochemistry research project students, Morgan and Hugo. Thank you for all your hard work and contributions to the lab @mcf-uom.bsky.social @fbmh-uom.bsky.social 🔬 #Science #HigherEd
Morgan and Hugo graduating in Medical Biochemistry from the University of Manchester
012
Reposted by Byron Lab
Ivaska Lab @ivaskalab.bsky.social · 04/12/2025
We are very happy to share our latest work exploring the role of newly synthetized integrin-α5 using RUSH. We found that a subset goes to the PM via unconventional secretion! Big thanks to all involved! Read more at doi.org/10.1083/jcb.... @mathildemathieu.bsky.social @martina-lerche.bsky.social
doi.org
Regulation of cell dynamics by rapid integrin transport through the biosynthetic pathway | Journal of Cell Biology | Rockefeller University Press
The study reveals that newly synthesized integrins can bypass the Golgi to be actively delivered to specific plasma membrane regions, where they enhance ce
02812
Reposted by Byron Lab
Doug Dyer @douglaspdyer.bsky.social · 20/11/2025
Delighted to share our new pre-print from PhD student Ziyun Zhang joint with @tracyh9494.bsky.social demonstrating that lung alveolar macrophages have a dense glycocalyx and interstitial macrophages do not, @mcrcellmatrix.bsky.social @lydiabeckeriii.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
Airway macrophage specific expression of a dense glycocalyx and its remodelling following viral infection
The glycocalyx is best studied for its regulation of immune cell trafficking from the vasculature into inflamed tissues. The glycocalyx is composed of a range of glycans and glyco-proteins that form a...
1239
Reposted by Byron Lab
Paraskevi Kritsiligkou @parikki.bsky.social · 11/11/2025
🌍🌎🌏Open to students worldwide! I m super excited for this project 🎉
054
Reposted by Byron Lab
Ben Goult @bengoult.bsky.social · 11/11/2025
🧠 Fully funded 4-year PhD studentship 🧠 Please repost BBSRC NWD project with @parikki.bsky.social and @iamabyron.bsky.social Come join us to look at how mechanical and oxidative stress signalling pathways converge on the synaptic scaffold protein talin. www.findaphd.com/phds/project...
findaphd.com
(BBSRC NWD) A novel redox mechanosignalling nexus in the synapse that is misregulated in neurodegeneration at University of Liverpool on FindAPhD.com
PhD Project - (BBSRC NWD) A novel redox mechanosignalling nexus in the synapse that is misregulated in neurodegeneration at University of Liverpool, listed on FindAPhD.com
149
Byron Lab @thebyronlab.bsky.social · 06/11/2025
Two days left to apply for a Medical Research Council-funded PhD opportunity in the lab. This is a student-led project, so you can work with us to develop an exciting project in a research area of mutual interest! www.bmh.manchester.ac.uk/study/resear... @mcf-uom.bsky.social @fbmh-uom.bsky.social
bmh.manchester.ac.uk
MRC Doctoral Training Partnership
Find out more about the Medical Research Council (MRC) Doctoral Training Partnership (DTP) studentships for postgraduate researchers undertaking PhDs in biomedical, clinical and health services areas.
021
Byron Lab @thebyronlab.bsky.social · 06/11/2025
Fantastic talks from the lab at this week's @mcf-uom.bsky.social Lab Showcase - well done Josie, Julio and Morgan! Calls for cake 🍰
Cake topped with icing, sprinkles and jelly beans to celebrate great presentations by Byron Lab members!
000
Reposted by Byron Lab
Isabela Corina Fortunato, PhD @icfortunato.bsky.social · 27/09/2025
Happy to share that my PhD has finally taken the shape of a paper! ✨ Huge thanks to all authors, especially @davidbrueckner.bsky.social & @ehannezo.bsky.social for leading the modeling and @raimonsunyer.bsky.social & @xaviertrepat.bsky.social for their invaluable supervision. 🧵👇
34412
Byron Lab @thebyronlab.bsky.social · 26/09/2025
Shoutout to our fantastic project and masters students! 🧪✨ It was a pleasure to have you in the lab @mcf-uom.bsky.social – your energy and hard work truly made a difference! 💫 #LabLife #CellBiology #ResearchStudents #ThankYou #AcademicLife @fbmh-uom.bsky.social @manchester.ac.uk
130
Reposted by Byron Lab
Sara Wickstrom @sarawickstrom.bsky.social · 12/09/2025
My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...
jobs.mpi-muenster.mpg.de
Computational image analyst (m/f/d)
The Max Planck Institute for Molecular Biomedicine in Münster, Germany, has an opening for a
18685
Byron Lab @thebyronlab.bsky.social · 08/09/2025
Fantastic time at the Adhere2 conference on cell adhesion - on the lovely Dalmatian coast. #CellBiology #research #conference
111
Byron Lab @thebyronlab.bsky.social · 18/07/2025
Very enjoyable visit to the @qmbci.bsky.social yesterday, discussing fantastic science and presenting our work 🔬 Thank you for warmly hosting, @tysonsharp.bsky.social! @susanagodinho.bsky.social @drtanyasoliman.bsky.social @cruk-cityoflondon.bsky.social @qmul.bsky.social #research #collaboration
Queen Mary University of London
040
Reposted by Byron Lab
Faculty of Biology, Medicine and Health @fbmh-uom.bsky.social · 16/07/2025
A new £50m Medical Research Council Centre is set to study how environmental exposures cause chronic inflammatory diseases. www.manchester.ac.uk/about/news/n...
manchester.ac.uk
New £50m MRC Centre to study how environmental exposures cause chronic inflammatory diseases
The environment is increasingly acknowledged to play a critical role in our risk of developing diseases, with 30,000 deaths attributed to air pollution alone in the UK each year. A new research centre...
12612
Reposted by Byron Lab
Johanna Ivaska @johannaivaska.bsky.social · 16/07/2025
Excited to share our most recent study on #integrintraffic #cancer #migration #focaladhesion by @ivaskalab.bsky.social @drpaulinamoreno.bsky.social Niklas Jäntti et al www.sciencedirect.com/science/arti...
sciencedirect.com
EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration
Epithelial protein lost in neoplasm (EPLIN), an actin-binding protein, has been described as both a tumor promoter and tumor suppressor in different c…
13915
Reposted by Byron Lab
Diego Fernando Garcia @diegofgar.bsky.social · 14/07/2025
We're Hiring: Postdoctoral Position in Cross-Linking Mass Spectrometry Join our team at the Center for Structural Mass Spectrometry at the Martin Luther University Halle-Wittenberg (Sinz Lab) to develop and apply cross-linking mass spectrometry techniques for studying protein interactions.
144
Reposted by Byron Lab
Worboys Lab @worboyslab.bsky.social · 14/07/2025
Delighted to advertise a collaborative postdoc position available in the lab to develop new proximity labelling tools, funded by a BBSRC Transformative Research Technology grant: www.jobs.manchester.ac.uk/Job/JobDetai... #ChemicalBiology #SyntheticChemistry
jobs.manchester.ac.uk
Research Associate in Synthetic Chemistry and Chemical Biology:Oxford Road
046
Byron Lab @thebyronlab.bsky.social · 09/07/2025
Just back from a fantastic research visit to the Regina Elena National Cancer Institute, Rome, working with Dr Paola Nisticò and the Tumor Immunology & Immunotherapy team 🔬 Amazing cancer biology research, inspiring discussions and such warm hospitality from the team ☀️ #CancerResearch #Collaboration
Several members of the Tumor Immunology and Immunotherapy team from the Regina Elena National Cancer Institute in Rome gathered around a table.
151
Reposted by Byron Lab
Yasset Perez-Riverol @ypriverol.bsky.social · 08/07/2025
Had a chat with @ajbrenes.com at #BSPR2025 about data reuse, and how some datasets, once combined and reused for a new biological question, are absolute gold. It's always worth depositing your data. 💿 Here are the statistics of his #HipSci dataset, which has remained at 2% after 6 years. 📈
193
Reposted by Byron Lab
Hallou Lab @halloulab.bsky.social · 17/03/2025
🚨 Paper Alert 🚨 Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!! www.nature.com/articles/s41...
nature.com
A computational pipeline for spatial mechano-transcriptomics - Nature Methods
The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic and mechanical state.
1013953
Reposted by Byron Lab
eupaproteomics.bsky.social @eupaproteomics.bsky.social · 17/03/2025
Free Hands-On Training in Mass Spectrometry Imaging (MSI)! A unique training opportunity in MSI, open to both national and international attendees in collaboration with BMSS and catapult. For more information please check this link: www.bmss.org.uk/meetings/bms...
023
Reposted by Byron Lab
Institute of Genetics and Cancer @uoe-igc.bsky.social · 13/03/2025
Do you want to play a pivotal role in groundbreaking research at IGC? In this role you will work at the intersection of computational and experimental science, leveraging cutting-edge technologies to address fundamental questions in genetics and disease. Apply by 31 March: edin.ac/3R5dEBU
Bioinformatician, apply by 31 March text overlaying image of IGC building
054
Reposted by Byron Lab
Benoit Ladoux @bladoux.bsky.social · 14/03/2025
Happy to share our new publication in @naturematerials.bsky.social on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats @luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉 www.nature.com/articles/s41...
16933
Reposted by Byron Lab
Sara Wickstrom @sarawickstrom.bsky.social · 10/03/2025
Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...
nature.com
Measuring and manipulating mechanical forces during development - Nature Cell Biology
This Review discusses the recent advances in experimental approaches to interrogate the mechanical forces that mediate tissue deformations during development, highlighting the insights afforded at bot...
116272
Reposted by Byron Lab
Faculty of Biology, Medicine and Health @fbmh-uom.bsky.social · 12/03/2025
It’s #BritishScienceWeek and our researchers, academics and students have been at Manchester Museum! Students from far and wide, alongside the general public and visitors to the museum, have been finding out about the exciting work going on in the Faculty @officialuom.bsky.social.
1123
Reposted by Byron Lab
FBMH Doctoral Academy @fbmhdocacad.bsky.social · 06/03/2025
Come and find out how the Protein and Metabolite Analysis group can support your research at the Protein and Metabolite Analysis 2025 Showcase! 📅 31 March 2025 | 🕒 9am - 3:00pm 📍 Michael Smith Building Lecture Theatre Register here: www.eventbrite.co.uk/e/protein-me...
001
Reposted by Byron Lab
FocalPlane @focalplane.bsky.social · 06/03/2025
@the-node.bsky.social #biologists100 reporter @jens-cells.bsky.social is putting together a conference survival guide. What are your top tips for getting the most out of your conference experience.
032
Reposted by Byron Lab
Manuel Thery @manuelthery.bsky.social · 05/03/2025
Unique opportunity to join the CytoMorpho Lab (in Paris ❤️) as a postdoc to work on the self-organization and polarization of reconstituted networks made of microtubules, motors and actin filaments in vitro. Experience required. Please Repost 🙏 thanks !
06277
Reposted by Byron Lab
Dylan Burnette @mag2art.bsky.social · 05/03/2025
"Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties" and are distinct from other large EVs both in their content and morphology. This video shows a blebbisome (magenta) in the same field of view as forming migrasomes (yellow). www.nature.com/articles/s41...
062
Reposted by Byron Lab
Chloé Yeung @ccstorytime.bsky.social · 05/03/2025
Maybe of interest to the talented ECR network of @themeshwork.bsky.social ? www.manchester.ac.uk/research/bic...
manchester.ac.uk
Bicentenary PhD Studentships and Fellowships | The University of Manchester
Learn more about the Bicentenary PhD Studentships and Fellowships launched as part of The University of Manchester's 200th year.
045
Reposted by Byron Lab
Clare Buckley Lab @buckleylab.bsky.social · 24/02/2025
Happy to share our new paper about working part-time in academia. We hope it can help to get the conversation going about this important aspect of EDI and research culture elifesciences.org/articles/106... @elife.bsky.social @emiliapsantos.bsky.social @englishse.bsky.social @hammofish.bsky.social
elifesciences.org
Point of View: To be, or not to be, part-time in academia
Part-time working can be beneficial for individual academics, and also for academia as a whole.
0125
Byron Lab @thebyronlab.bsky.social · 05/03/2025
Fantastic postdoc opportunities available @fbmh-uom.bsky.social! 💡 Please get in touch if you're interested in using biomaterials, cell biology, 'omics technologies and data science to investigate cell adhesion networks and gene expression in cancer #science #research #jobs #careers
011
Reposted by Byron Lab
Kate Miroshnikova @katemiro.bsky.social · 08/01/2025
Excited to share the first paper from my lab 🤩 - a great collaboration with Dani Fachinetti lab - we discover a #mechanosensitive nuclear envelope #checkpoint that arrests cells directly post chromosome mis-segregation rdcu.be/d5AC9 👇🧵 #cancer #mechanics #p53 #chromatin
815040
Reposted by Byron Lab
dfachinetti.bsky.social @dfachinetti.bsky.social · 08/01/2025
#1 Happy to share our last work published in @NatureCellBio about a new cell cycle checkpoint that senses nuclear shape & mechanics to guarantee genome integrity www.nature.com/articles/s41.... Great work from @sol-herve.bsky.social & Andrea Scelfo in close collaboration with @katemiro.bsky.social
nature.com
Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpoint - Nature Cell Biology
Hervé, Scelfo et al. show that chromosome mis-segregation induces mTORC2- and ATR-mediated p53 activation through a mechanosensitive checkpoint at the nuclear envelope triggered by altered heterochrom...
1010332
Reposted by Byron Lab
Manchester Institute of Biotechnology @uommib.bsky.social · 21/12/2024
Did you catch us on BBC Breakfast this morning? Dr Neil Dixon and Dr Micaela Chacón explain how biotechnology could be used to help us with our Christmas waste. Start from 17:45: www.bbc.co.uk/iplayer/epis...
202
Reposted by Byron Lab
The University of Manchester @manchester.ac.uk · 17/12/2024
World leading researchers at our University are making an impact right around the world 🧬🔬 Here’s a taste of some of @fbmh-uom.bsky.social's most popular and interesting stories from 2024 👇 www.manchester.ac.uk/about/news/2...
manchester.ac.uk
2024 in the news from the Faculty of Biology, Medicine and Health
Welcome to the 2024 annual review from the biology, medicine and health beat. Yet again, our world leading researchers are making an impact right around the world, so here’s a taste of  some of our mo...
144
Byron Lab @thebyronlab.bsky.social · 20/12/2024
📣 PhD opportunity in the lab! 💡 Are you interested in developing biomaterials to understand how cancer cells sense their surroundings to control gene activity? 🔗 For info on the project, and for details on how to apply, click here: www.findaphd.com/phds/project... 📧 Do get in touch if interested!
findaphd.com
(BBSRC NWD) Developing biomaterials to engineer how cancer cells sense force to regulate gene expression at The University of Manchester on FindAPhD.com
PhD Project - (BBSRC NWD) Developing biomaterials to engineer how cancer cells sense force to regulate gene expression at The University of Manchester, listed on FindAPhD.com
114
Reposted by Byron Lab
The University of Bath @uniofbath.bsky.social · 13/12/2024
We welcomed scientists from around the world to Bath this week for the annual Skin@Bath Symposium, who brought together global experts to discuss cutting-edge research in skin research, including therapies for skin-related disorders, such as skin cancers and arthritic psoriasis. #WeAreInternational
3103
Byron Lab @thebyronlab.bsky.social · 13/12/2024
Great to be at the Skin@Bath Symposium learning about all things skin! Thrilled to have presented our work in the squamous cancers session, expertly chaired by @walkolab.bsky.social from @qmulfmd.bsky.social First time at this meeting, so v nice to meet new colleagues @birdbathcharity.bsky.social
Bath Abbey lit up on a dark evening, surrounding by illuminated Christmas market stalls.Adam Byron (@iamabyron@bsky.social) presenting a talk at the International Skin@Bath Symposium.
100
Reposted by Byron Lab
Sally Lowell @cellysally.bsky.social · 10/12/2024
It is becoming increasingly confusing to work out where to publish if you want to comply with your funders OA policy (or with your own principles). This tool is very helpful journalcheckertool.org
journalcheckertool.org
Journal Checker Tool: Check which publishing options are supported by your funder’s OA policy |
JCT enables researchers to check whether they can comply with their funders Plan S aligned OA policy based on the journal, the funder and the institution affiliated with the research to be published.
2249
Byron Lab @thebyronlab.bsky.social · 05/12/2024
Fantastic to see the insides (and outside) of the brand new Dalton building @manmetuni.bsky.social - amazing space housing the Faculty of Science and Engineering. @iamabyron.bsky.social gave a Department of Life Sciences Research Seminar with a great view of the city!
External view of the new Dalton building at Manchester Metropolitan University Adam Byron delivering a talk at the Department of Life Sciences Research Seminar series at Manchester Metropolitan University. Photograph by Jim Pritchett
031
Reposted by Byron Lab
Macaulay Turner @macaulayturner.bsky.social · 22/11/2024
Get down to the engineering building to see some NanoSIMS #UoM-TBM
092
Byron Lab @thebyronlab.bsky.social · 29/11/2024
Visited the Tiny But Mighty biotech image exhibition @official-uom.bsky.social today. A collection of tiny things that have big impact on biology, engineering and health! Wonderful images from colleagues @uomscieng.bsky.social @fbmh-uom.bsky.social @cruk-mi.bsky.social @mcf-uom.bsky.social #sciart
An image introducing the University of Manchester Tiny But Mighty biotechnology image exhibitionSpeeding up research, an image by Craig Markin showing a high-throughput microfluidic enzyme kinetics deviceUnderstanding cell behaviour, an image by Adam Byron displaying network analysis of a cell-adhesion protein complexA view across the exhibition space at the University of Manchester
172
Byron Lab @thebyronlab.bsky.social · 22/11/2024
A nice Bluesky intro. Plus, hard to resist not having a go! scholargoggler.com
Cloud of words in various colours and sizes based on the Google Scholar profile for Adam Byron. Some of the largest words include cell, analysis, cancer, adhesion, proteomic, integrin, complexes, breast, signalling, extracellular, matrix, novel, protein, complex, proteomics, regulates, stem, expression, human, role, activation, array, data, FAK, gene, immune, kindlin-1, lobular, networks, assembly
0121
Byron Lab @thebyronlab.bsky.social · 20/11/2024
👋 #introduction: We are a new cell systems biology team @fbmh-uom.bsky.social #UoM. We study #CellAdhesion #networks in health and disease, especially #cancer. Fascinated by how adhesion proteins help #cells function in so many ways!
041