Upon DNA breakage, a genomic locus undergoes alterations in three-dimensional chromatin architecture to facilitate signaling and repair. Although cells possess mechanisms to repair damaged DNA, it is ...

Many questions remain regarding Earth’s earliest crust owing to the rarity of Hadean (>4.03 billion-year-old) rocks and minerals. The Nuvvuagittuq Greenstone Belt (NGB) in Canada may be the only known...

It took Ed Roberts over a year to find a senior scientist to work at his cancer research laboratory in Scotland, a delay he blames on high UK visa costs that made it harder to attract international workers.

Skin injury releases damage-encoded systemic signals that can initiate immunity to novel antigens introduced at distal barrier sites.

More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada.

A population of neutrophils in the skin produces extracellular matrix, providing a defence strategy by reinforcing the barrier properties of the skin and helping to block the entry of pathogens.

The Trump administration’s rapid terminations of NIH grants is its most aggressive attempt yet to control American science.

The US government has begun slashing US$400 million in research grants at Columbia University over pro-Palestinian campus protests.

The brain of a man who died nearly 2000 years ago was turned to glass by extreme conditions during the eruption of Mount Vesuvius. Researchers studied the strange material found in the man’s skull and spine and deduced the presence of a super-heated ash cloud that would have caused the tissue to first liquify then rapidly cool into glass - a unique event that has even preserved some brain structures. Read the paper here: https://go.nature.com/4bnpr81 For more stories like these sign up for the Nature Briefing: An essential round-up of science news, opinion and analysis, free in your inbox every weekday: https://go.nature.com/371OcVF

Genetically modified mice have traits geared towards cold tolerance, in step towards modifying elephants

US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.

Adipose manipulation transplantation can reduce tumor growth and proliferation in vitro and in mouse models.

As US federal grants remain frozen and budget cuts loom, anxiety and fear grip early-career researchers.

High living costs paired with stagnant stipends are being blamed for a drop in PhD enrolments in several countries.

Union describe reductions as ‘cruel’ as university says it will run out of money without changes

ID: 4897. Title: Postdoctoral Research Associate . Application Deadline:

Conventional chemotherapy has successfully cured millions of patients with cancer, yet the mechanisms of action for this remain unclear. In this Perspective, Letai and de The assess the existing mecha...

Large-scale experimental analysis of Human Domainome 1, a library containing more than 500,000 missense mutation variants across more than 500 human protein domains, reveals that 60% of pathogenic mis...

In their Review article, Fuchs and colleagues discuss how a single or a few mutations in adult cells can lead to invasive cancers without a high mutational burden, demonstrating that non-genetic ...

Lu et al. perform systematic functional analyses using data from the TRACERx cohort of patients with non-small-cell lung cancer and delineate how FAT1 regulates homologous recombination repair, chromo...

This case series examines treatment with anti–programmed cell death 1 (PD1) immunotherapy for patients with basal cell nevus syndrome.

All of statistics and much of science depends on probability — an astonishing achievement, considering no one’s really sure what it is.

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