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David Schoppik

@schoppik.com
1.3K followers 1K following 674 posts

Studying how balance develops, functions, and fails at NYU Langone. www.schoppiklab.com . "And worse I may be yet: the worst is not so long as we can say, 'This is the worst.’” -- King Lear (Act IV Scene I)

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David Schoppik @schoppik.com · 29/09/2026
Ever relevant @xkcd.com xkcd.com/927/
xkcd.com
Standards
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Michael Lin, MD PhD @michaelzlin.bsky.social · 29/09/2026
Excited to share a new study from our lab in Cell: “Non-invasive control of gene editing in vivo by photoswitchable Cas12f and focused ultrasound” We engineered a compact CRISPR system that can be activated at specific locations in the body using focused ultrasound (🧵) www.cell.com/cell/fulltex...
cell.com
Non-invasive control of gene editing in vivo by photoswitchable Cas12f and focused ultrasound
Remote activation of a single-AAV-deliverable photoswitchable Cas12f system enables precise spatial and temporal control of genome editing in deep tissues without surgery or implanted devices.
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David Schoppik @schoppik.com · 29/09/2026
Cool, congrats, great, happy for you, and do call me when you get to Deuteronomy.
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David Schoppik @schoppik.com · 29/09/2026
"They get rich, you die. It's trying." was right there 😅
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Tessa Montague @tessamontague.bsky.social · 29/09/2026
I'm excited to share our new preprint: Generation of a transgenic cephalopod tinyurl.com/pc86jxz8 Cephalopods (cuttlefish, octopus & squid) are crazy critters that dynamically camouflage to their surroundings by changing the color, pattern, & texture of their skin, which they control w their brain.
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 28/09/2026
Repeated Inertial Stimulation Reveals Divergent Plasticity in Peripheral and Central Vestibular Pathways www.biorxiv.org/content/10.64898/20…
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Rebecca Solnit @rebeccasolnit.bsky.social · 28/09/2026
Campus rape is really widespread; statistics suggest a significant percent of women who go to college will be raped there; feminism opened up a good conversation about it around 2012-13; it's weird when people treated Cornell like an isolated rather than dramatic example of a pervasive problem.
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Rainer Friedrich @rainerfriedrichlab.bsky.social · 26/09/2026
Precise structural and functional organization of the olfactory bulb neuropil early in development, revealed by volume EM, dense reconstruction and 2P calcium imaging in zebrafish. Great work by Ruth and others in collaboration with @michalwj.bsky.social www.biorxiv.org/content/10.6...
biorxiv.org
Fine ultrastructural organization of glomerular neuropil in the developing zebrafish olfactory bulb
Across animal phyla, odor information is represented in the first olfactory processing center by combinatorial activation of discrete glomeruli. To examine how this organization of olfactory processin...
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Scott Juntti @scottjuntti.bsky.social · 27/09/2026
When a fish sees the world move, it immediately swims with it. This is the optomotor response: a visual reflex found across animals that helps us maintain our position and orientation as our surroundings appear to drift. 🐟👀
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David Schoppik @schoppik.com · 27/09/2026
Love that alternating pec fin gait!
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David Schoppik @schoppik.com · 26/09/2026
<waiting patiently w/CB over here>
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Caroline Bartman @cbartman.bsky.social · 26/09/2026
Are there key discoveries made with spatial RNA seq? Or what are your favorite spatial rna seq papers? Pls reski!
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David Schoppik @schoppik.com · 26/09/2026
Rainy Saturday project complete.
Picture of granola with apricots, dried cherries / blueberries, pecans and pumpkin seeds.
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David Schoppik @schoppik.com · 26/09/2026
IA IA oh?
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David Schoppik @schoppik.com · 26/09/2026
Amazing sky before the storm tonight in #nyc.
The Chrysler and Chanin buildings against a purple-pink sky.
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David Schoppik @schoppik.com · 25/09/2026
Like the monk said, "Before enlightenment: carry water, chop wood. After enlightenment: carry water, chop wood."
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David Schoppik @schoppik.com · 25/09/2026
static.klipy.com
Gromit Snapping Fingers
ALT: Gromit Snapping Fingers
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David Schoppik @schoppik.com · 25/09/2026
prob worth deleting this one to fix that typo
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Cedric Feschotte @cedricfeschotte.bsky.social · 24/09/2026
Thrilled to see this published today! Truly special because we made the initial discovery >15 yrs ago! We found two copies of a human gene called BC200 embedded in a human poxvirus. BC200 blurs the line between gene & transposon—both functional & mutagenic! www.science.org/doi/10.1126/... 🧵1/n
science.org
Escape of the BC200 gene to a human poxvirus reveals its persistent transposition in primates
Transposable elements mobilize within and occasionally between genomes, including from host to virus. We identified two insertions of the human BC200 noncoding RNA gene in the poxvirus molluscum conta...
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David Schoppik @schoppik.com · 24/09/2026
I wonder if there is much overlap between the gatekeepers at beauty pageant fellowships and study section members....
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Portugues Lab @portugueslab.bsky.social · 24/09/2026
The Department of Neurobiology and Behavior at Cornell University is hiring! Come and do cutting edge research on the neural basis of natural behaviors at NBB (nbb.cornell.edu). No animal too small, no behavior too strange! Apply here: academicjobsonline.org/ajo/jobs/32592
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David Schoppik @schoppik.com · 24/09/2026
Yes, there’s a superior (Castelvetrano) and inferior (Kalamata).
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David Schoppik @schoppik.com · 24/09/2026
That deserves a proper 👏🏻
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David Schoppik @schoppik.com · 24/09/2026
Let's be fair Harmit none of our first drafts are easy....
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Matt Lovett-Barron @mlovettbarron.bsky.social · 23/09/2026
Our lab's latest paper on the neurobiology of collective behavior is now published www.nature.com/articles/s41... This is the work of a great team in the lab - led by Jo-Hsien Yu, with Geoff Meyerhof, Jimjohn Milan, and Julia Napoli @nature.com @danionella.bsky.social
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Ann Clemens @annmclemens.bsky.social · 12/08/2026
preprint🚨 ✨A Stickiness Response System in Rats tinyurl.com/4wnu88v9 What underlies that sticky, icky feeling? Sticky sensing is surprisingly underexplored. we investigated its neural and behavioural basis Congrats to Sandra, @simonerencken.bsky.social @jasmine-stone.bsky.social Adam, Tom & Pam! 👏
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Florian T. Merkle, PhD @florianmerkle.bsky.social · 22/09/2026
Seeking a PhD at Cambridge in collaboration with NovoNordisk? Consider this funded opportunity titled "Human cellular models of leptin signalling and resistance": bbsrcdtp.lifesci.cam.ac.uk/project-refe... Application details: bbsrcdtp.lifesci.cam.ac.uk/how-apply Thanks for spreading the word!
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Dan Grimes @dangrimes.bsky.social · 22/09/2026
1/11. New preprint from our lab! Serotonergic Control of Spine Morphology During Growth in Zebrafish www.biorxiv.org/content/10.6...
biorxiv.org
Serotonergic Control of Spine Morphology During Growth in Zebrafish
Scoliosis is a three-dimensional deformity of the vertebral column that commonly emerges during growth, yet the biological mechanisms that initiate and drive curve progression remain poorly understood...
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David Schoppik @schoppik.com · 20/09/2026
Link doesn’t resolve correctly?
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Margarita Parada-Kusz @margaritapk.bsky.social · 18/09/2026
Two parallel neural ectoderm progenitors contribute to the developing brain www.nature.com/articles/s41...
nature.com
Two parallel neural ectoderm progenitors contribute to the developing brain - Nature Neuroscience
This study shows that the brain arises from two distinct progenitors: one forms the forebrain and midbrain, whereas the other generates the hindbrain. These insights enable the generation of human hin...
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Sweta Agrawal @hokuba.bsky.social · 16/09/2026
The Agrawal lab has published its first paper! "Sticking the landing: leg mechanosensory feedback coordinates the transition from flight to landing" www.biorxiv.org/content/10.6... This project was led by a technician in the lab, Tse-Wei (Wayne) Kuo. Brief 🧵on what we found
agrawal-lab-workspace.slack.com
Slack
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David Schoppik @schoppik.com · 14/09/2026
Are you even playing Wisconsin?
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David Schoppik @schoppik.com · 12/09/2026
This is timely, lucid, and something worth having handy the next time it comes up. Because it will keep coming up.
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David Schoppik @schoppik.com · 12/09/2026
Thank you! This is exceptionally lucid & helpful.
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 11/09/2026
“the only certainty we have is the certainty we had at the start: At fifteen seconds after 9:41 a.m., on September 11, 2001, a photographer named Richard Drew took a picture of a man falling through the sky—falling through time as well as through space…The picture is his cenotaph“
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Philippe Batut @philippebatut.bsky.social · 10/09/2026
🧬🔬 Why are enhancers transcribed and how does that impact gene regulation? I’m really excited to share our new paper in @science.org showing that noncoding RNAs control the timing of gene activation in embryos. With Mike Levine #ScienceResearch @columbiamed.bsky.social A few highlights below... 🧵👇
science.org
Noncoding transcription controls the developmental dynamics of long-range gene regulation
The genomic regions regulating gene expression are often themselves transcribed into a variety of noncoding RNAs (ncRNAs). However, the regulatory roles of this noncoding transcription remain largely ...
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David Schoppik @schoppik.com · 11/09/2026
This looks really neat. Excited to read the full paper.
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Rainer Friedrich @rainerfriedrichlab.bsky.social · 10/09/2026
Just out in Nat Neurosci: disentangling of neural odor manifolds in "olfactory cortex" of adult zebrafish after learning. Great work by Bo, Nesibe et al and wonderful collaboration with @sueyeonchung.bsky.social that fundamentally changed my view of olfactory cortex. www.nature.com/articles/s41...
rdcu.be
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David Schoppik @schoppik.com · 10/09/2026
This is a great resource that encapsulates a lot of hard-won knowhow.
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H. P. Read @readhpr.bsky.social · 06/09/2026
Lovely article about a 99-year-old retired math professor who recently published a major result. It's the story of mentorship and multi-generational collaboration. www.nytimes.com/2026/09/06/s...
nytimes.com
The 92-Year-Old Mathematician and the Teenage Apprentice (Gift Article)
Joan Birman thought her major discoveries were behind her. Then came an email from a young neighbor — a girl who knew little but wanted to learn.
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David Schoppik @schoppik.com · 06/09/2026
100% agree! This will be the first year in decades that I don't make this cake, but it's only b/c my daughter got into baking and I am excited to pass the torch....
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David Schoppik @schoppik.com · 05/09/2026
Excellent points. This might be your best “I am large, I contain multitudes.” thread yet. Thanks.
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Mekka Okereke @mekka.mekka-tech.com · 05/09/2026
Nathan wrote a good article. I'm quote tweeting in the Black way (to talk about a different point without derailing his thread). 🤔If Ben thinks you need to play football to build character, learn teamwork, leadership, etc, and girls don't play football... what does that say about his view of women?
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Andrew Straw @andrewstraw.bsky.social · 04/09/2026
We are hiring! Come join us in the Straw Lab at the @biologyunifreiburg.bsky.social . Seeking a scientist to work on the neural and computational mechanisms of visual navigation in honey bees. uni-freiburg.de/en/job/00005...
Bee trajectories in agricultural landscape and two photon microscope for in-vivo calcium activity imaging.
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David Schoppik @schoppik.com · 04/09/2026
Congrats!
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David Schoppik @schoppik.com · 02/09/2026
I thought the point was to empty the building? 😝
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David Schoppik @schoppik.com · 01/09/2026
jo-newyork.com is truly special and it looks like they have spots for the 5:30-6 seating tomorrow b/c nobody really knows about it yet.
jo-newyork.com
Jō -Japanese cuisine-
JŌ(縄)refers to a rope composed of plant stalks, fibers, or paper, that in Japanese culture has been utilized for centuries for various purposes.
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Al Yankovic @alyankovic.bsky.social · 31/08/2026
“Lost media” no longer! I finally got permission to upload “AL’S BRAIN,” an 11-minute educational 3-D film attraction which ran at the Orange County and Western Washington fairs, and hasn’t been seen publicly since 2009. You can watch the whole thing here: youtu.be/2xujU87ZHt4
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David Schoppik @schoppik.com · 31/08/2026
On the off-chance you're serious or someone reading this is, this sticks nicely to the underside of the fabric and you'll feel so silly about putting it there that you'll never forget your umbrella again: www.elevationlab.com/collections/...
elevationlab.com
AirTag Fabric Extreme
The first waterproof AirTag fabric mount. Installs in seconds to luggage, purses, bags or jackets. Flexes &amp; moves with your fabric. Discreet. Top easily screws on and off.  Engineered to withstand...
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Dayu Lin @moccalin.bsky.social · 26/08/2026
Happy to share our new study comparing aggression level across 7 strains of mice, led by a talented undergraduate student, Xiuzhi Dai. Strain differences in aggression can be explained a lot by differences in the physiological properties of VMHvl cells. www.nature.com/articles/s41...
nature.com
Hypothalamic representation of aggressiveness across mouse strains - Nature Communications
Genetics profoundly influences aggression by shaping neural circuits, but the underlying mechanisms remain unclear. Here, authors show that strain differences in male mouse aggression are linked to di...
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