A new Gallup survey reveals that more Americans are choosing to abstain from alcohol.

The criticism of The Lancet, NEJM and JAMA is not new, but the health secretary may use his position to influence research that journals publish.

The manuscript reports on patient with a USP5 mutation that gives rise to insensitivity to pain. The patient’s pathology is phenocopied in a knock-in mouse

YouTube video by Broad Institute

Sleep is an essential component of our daily life. A mutation in human salt induced kinase 3 (hSIK3), which is critical for regulating sleep durati...

Podcast Episode · Parallax by Ankur Kalra · 04/28/2025 · 55m

NEW HAVEN, CT—Calling such concern for linguistic precision a clear indicator of a thriving country, a panel of historians from Yale University issued a statement Thursday announcing that quibbling over the exact definition of a concentration camp was a sign of a healthy society. “Studies of the past tell us that nitpicking the particular semantics […]

Nature Metabolism, Published online: 15 April 2025; doi:10.1038/s42255-025-01277-yA Nature Metabolism study shows that, under acute stress, fatty acids liberated by lipolysis of white fat cells cause release from local macrophages of the growth-differentiation factor GDF15, which, in turn, binds to the receptor GFRAL in the brain, evoking anxiety.

Bile acid metabolism meets glucagon-like peptide 1 signaling in osteoarthritis

Diabetes is a leading cause of global mortality and disability, and its economic burden is substantial. This Review focuses on type 2 diabetes, which makes up 90–95% of all diabetes cases. Type 2 diab...

Nature Reviews Genetics, Published online: 20 March 2025; doi:10.1038/s41576-025-00833-2In this Journal Club, Minoli Perera reflects on a 2005 sequencing study by Cohen et al., who discovered two common loss-of-function mutations with large effects on plasma cholesterol levels thanks to the inclusion of African American study participants.

Amid growing wealth disparity, we have little information on how health among older Americans compares with that among older Europeans across the distribution of wealth. We performed a longitudinal...

Administration officials reversed a decision made during the Biden presidency that would have given millions of people access to weight-loss drugs paid for Medicare and Medicaid.

Explore the role of cardiovascular health in maternal well-being. Learn warning signs, improve communication, and access life-saving tools.