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Jim Januzzi

@jimjanuzzi.bsky.social
1K followers 295 following 32 posts

Formerly known as @JJHeart_Doc on the "bird" app. Professor of Medicine, Harvard; Cardiologist, MGH; Chief Scientific Officer, Baim Institute; Team MD for the Boston Red Sox. I used to be disgusted. Now I try to be amused.

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Reposted by Jim Januzzi
American College of Cardiology @accintouch.bsky.social · 11/11/2025
“Philanthropy can lead to some really remarkable changes in how leadership can be cultivated, research can be distributed and health care can be improved.” 🗣️ ACC Philanthropic Fundraising Committee Chair Dr. @jimjanuzzi.bsky.social 📽️ bit.ly/4qQrkBv #ACCPresident @chriskramermd.bsky.social
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Jim Januzzi @jimjanuzzi.bsky.social · 31/10/2025
I don't post much anymore, but I felt it worth reminding our colleagues that "follow up with your cardiologist ASAP" is not a guideline supported move nor a therapeutic intervention for someone discharged with ongoing new onset atrial flutter with RVR on a Friday afternoon. #cardiosky
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JACC Journals @jaccjournals.bsky.social · 29/09/2025
Selective in vitro enhancement of cardiac myosin motor function and myofilament force generation by danicamtiv prompted clinical evaluation. A short course of danicamtiv was generally well tolerated in participants with #DCM bit.ly/4mE3vcM #HFSA2025 #JACC #cvGenetics @jimjanuzzi.bsky.social
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Jonathan Davis, MD, MPHS @jonathandavishf.bsky.social · 14/05/2025
Short & sweet! Check out our review of #SGLT2i & #GLP1RA in #HeartFailure! Great work Jose Lopez & team! @ucsfcardiology.bsky.social @amitgoyalmd.bsky.social @robmentz.bsky.social @dranulala.bsky.social @jimjanuzzi.bsky.social @sjgreene-md.bsky.social www.uscjournal.com/articles/sho...
uscjournal.com
The Short and Sweet on Sodium–Glucose Cotransporter Inhibitors and Glucagon-like Peptide-1 Receptor Agonists in Heart Failure
Heart failure (HF) affects 6 million people in the US, and type 2 diabetes (T2D) is a significant risk factor for HF. Since 2008, regulatory agencies have required cardiovascular safety trials
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Shalen Fairbanks @shaykim.bsky.social · 10/05/2025
Great presentation by @jimjanuzzi.bsky.social at #ACCAsia in Singapore on optimizing decongestion using diuretics and GDMT in patients with HF. Access more HF resources in the @accintouch.bsky.social Guidelines Hub: acc.org/guidelines
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Parham Eshtehardi MD @cardioobdoc.bsky.social · 06/05/2025
Get to Know Your Leaders | Leading With Purpose: Meet Chris Kramer, MD, FACC @chriskramermd.bsky.social #CardiologyMagazine #CardioSky www.acc.org/Latest-in-Ca... @accintouch.bsky.social @jaccjournals.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @vietheartpa.bsky.social
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Jim Januzzi @jimjanuzzi.bsky.social · 17/04/2025
The weekend cannot come fast enough.
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B Grrl @bgrrl.bsky.social · 16/04/2025
Hope for tx of nHCM: According to the company, this partial fatty acid oxidation (pFOX) inhibitor is an oral compound that promotes a shift in the heart’s preference from fatty acids to glucose, resulting in energy generation by the mitochondria. #HCM #CardioSky #Cardiomyopathy #Cardiology
pharmaceutical-business-review.com
Imbria secures $57.5m to advance ninerafaxstat through Phase IIb trial
Imbria has secured $57.5m in a Series B funding round to support the progression of ninerafaxstat through a Phase IIb trial in nHCM.
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Reposted by Jim Januzzi
Henry Han @hancardiomd.bsky.social · 15/04/2025
Clinical and plasma proteomic characterization of heart failure with supranormal left ventricular ejection fraction: An emerging entity of heart failure #EJHF @escardio.bsky.social #CardioSky @shelleyzieroth.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @cardioobdoc.bsky.social
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Jim Januzzi @jimjanuzzi.bsky.social · 03/04/2025
Back to the Garden with @julijanuzzi.bsky.social @celticsnba.bsky.social
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Jim Januzzi @jimjanuzzi.bsky.social · 01/04/2025
I am so incredibly grateful to the @accintouch.bsky.social for the honor of being named the 2025 Distinguished Clinical Researcher. I am blessed to have stood on the shoulders of giants during my career and am thankful to @mgbresearch.bsky.social and #BaimInstitute for support.
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Anju Bhardwaj MD @docbhardwaj.bsky.social · 01/04/2025
Congratulations @jimjanuzzi.bsky.social Very well deserved 👏👏
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Dr Ada Stefanescu @dradastefanescu.bsky.social · 01/04/2025
Congratulations @jimjanuzzi.bsky.social on your @accintouch.bsky.social Distinguished Scientist Award!! #ACC25
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American College of Cardiology @accintouch.bsky.social · 31/03/2025
Congratulations to new #ACCPresident Christopher M. Kramer, MD, FACC! Inspired by a movie classic, he shared: “Today I want to talk to you about two Fantastic Voyage-Related themes: innovation and mentorship.” 💬 bit.ly/41RJlF6 @ChrisKramerMD #ACC25 #ACCLeadership
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Cristina Popa @nephroseeker.medsky.social · 30/03/2025
FRESH-UP Trial #ACC25 #medsky RCT comparing liberal vs restricted fluid intake (≤1500 ml/d) in 504 pts with stable chronic HF 🌊No difference in status health quantified by Kansas City Cardiomyopathy Questionnaire at 3 mths 🌊 More thirst distress with restriction www.nature.com/articles/s41...
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Joe Cuthbert @jjcuthbert.bsky.social · 31/03/2025
Fluid restriction associated with trend to worse QoL and greater thirst in stable outpatients with HF. No difference in safety. www.nature.com/articles/s41...
nature.com
Liberal fluid intake versus fluid restriction in chronic heart failure: a randomized clinical trial - Nature Medicine
While fluid restriction is typically recommended for patients with chronic heart failure, this randomized clinical trial showed no difference in health status, as assessed by patient-reported outcomes...
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allisonghaysmd.bsky.social @allisonghaysmd.bsky.social · 30/03/2025
Terrific @accintouch.bsky.social @acc25 session on the intersection of heart failure and imaging. Great job @purviparwani.bsky.social @michaelsalerno.bsky.social moderating the interesting case-based discussions @jimjanuzzi.bsky.social
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Jim Januzzi @jimjanuzzi.bsky.social · 27/03/2025
Opening day for the @redsox.com Let’s go #MLB2025 #DirtyWater @heartbobh.bsky.social
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Jim Januzzi @jimjanuzzi.bsky.social · 24/03/2025
Happy birthday to a person who makes the world more beautiful. Walking the beach where just a few months ago our buddy was having the time of his life. Glad to share the moment together. There are blue skies beyond this. Happiest of birthdays, RSJ. @robertasensen.bsky.social
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Jim Januzzi @jimjanuzzi.bsky.social · 22/03/2025
I did not have habitually watching eaglets on my 2025 bingo card but we are completely here for #JackieandShadow and their babies. #FOBBV #eagles @robertasensen.bsky.social
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Jim Januzzi @jimjanuzzi.bsky.social · 19/03/2025
Enough is enough. I have deleted my Twitter account. Not worth it anymore.
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Jim Januzzi @jimjanuzzi.bsky.social · 18/03/2025
One more day to purchase tickets! www.acc.org/75thGala #cardiosky
acc.org
75thgala - American College of Cardiology
The ACC Foundation Anniversary Gala will unite our members, friends and partners to celebrate the remarkable achievements of the past 75 years and raise funds to continue advancing our Mission.
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Jim Januzzi @jimjanuzzi.bsky.social · 03/03/2025
Courtside @thebostonceltics.bsky.social with @robertasensen.bsky.social and the fam.
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Parham Eshtehardi MD @cardioobdoc.bsky.social · 19/02/2025
In pts undergoing 99mTc PYP imaging for suspected #ATTR, hs-cTnT & NT-proBNP can effectively rule out diagnosis, although in a small subset of patients #CardioSky www.jacc.org/doi/10.1016/... @jaccjournals.bsky.social @vietheartpa.bsky.social @load-dependent.bsky.social @jimjanuzzi.bsky.social
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Jim Januzzi @jimjanuzzi.bsky.social · 12/01/2025
Game time, Courtside with @julijanuzzi.bsky.social @thebostonceltics.bsky.social
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Parham Eshtehardi MD @cardioobdoc.bsky.social · 02/01/2025
Aortic Stenosis, Heart Failure, & Aortic Valve Replacement #CardioSky #MedSky #TAVR #TAVI @jama.com @jimjanuzzi.bsky.social @robmentz.bsky.social @drdevireddy.bsky.social @hvanspall.bsky.social @anastasiasmihaili.bsky.social jamanetwork.com/journals/jam...
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Jim Januzzi @jimjanuzzi.bsky.social · 26/12/2024
Really interesting data about how BAG3 variants modify cardiomyopathy risk.
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Jim Januzzi @jimjanuzzi.bsky.social · 25/12/2024
Merry Christmas to all My favorite gift of the season is now on the tree. #IYKYK
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Greg Bryson @glbryson.bsky.social · 21/12/2024
Older news but still noteworthy. Among patients with HFrEF and HFpEF, withdrawal of SGLT2i led to increased CV death, HF symptoms, fasting glucose, BP, BNP and decreased Hb. Events occurred within 30 days of withdrawal. Are we sure that's what we want to do preop? www.ahajournals.org/doi/10.1161/...
ahajournals.org
Blinded Withdrawal of Long-Term Randomized Treatment With Empagliflozin or Placebo in Patients With Heart Failure | Circulation
BACKGROUND: It is not known whether the benefits of sodium-glucose cotransporter 2 inhibitors in heart failure persist after years of therapy. METHODS: In the EMPEROR-Reduced (Empagliflozin Outcome ...
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Jim Januzzi @jimjanuzzi.bsky.social · 21/12/2024
The holidays begin with a little snow. It’s hard to tell but these trees are 30-40 feet tall. Happy Friday, all.
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Harlan M. Krumholz @hmkyale.bsky.social · 11/12/2024
Patients are also welcome to suggest research questions. For all: Submit your questions here: www.jacc.org/priorities-f... Together, we can address the evidence gaps that matter most! #Cardiology #ClinicalResearch #HeartHealth
jacc.org
JACC | Priorities for Evidence Generation
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Harlan M. Krumholz @hmkyale.bsky.social · 11/12/2024
Clinicians, your voice matters! 🩺 @JACCJournals & @US_FDA are teaming up to tackle urgent evidence gaps in cardiovascular care. Share the key questions you face in practice about FDA-regulated products and help shape the future of research. www.jacc.org/doi/10.1016/...
jacc.org
Giving Cardiovascular Clinicians a Voice in Evidence Generation: A Collaboration Between FDA and JACC
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Chris Georgenes @bostondrummer.bsky.social · 07/12/2024
It Ain’t Over ‘Till It’s Over by Lenny Kravitz #drumcover
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Harriette Van Spall MD MPH 🇨🇦 @hvanspall.bsky.social · 02/12/2024
An R2 as high as 90% is rare!! 🔺In this metaanalysis of #HF #RCTs, Tx effect of interventions on HF 🏥s & all-cause 🏥s were HIGHLY correlated (R2 = 90.1%; 95% CI 62.3%-99.8%) 🔺HHF is a suitable clinical endpoint in HF RCTs for many reasons, including the one above
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Harlan M. Krumholz @hmkyale.bsky.social · 28/11/2024
As Editor-in-Chief of JACC, I’m thankful for the inspiring community that advances cardiovascular health. From groundbreaking submissions to engaged readers and reviewers, and our team, you make our journey possible. Here’s my Thanksgiving message of gratitude:
buff.ly
Happy Thanksgiving | JACC
JACC editor-in-chief Harlan M. Krumholz, MD, SM relays his gratitude for the past few months and enthusiasm for staff, editors, reviewers, readers, and autho...
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Jim Januzzi @jimjanuzzi.bsky.social · 01/12/2024
Starting the day with some music theory and coffee with #RickBeato www.youtube.com/watch?v=FaMP...
youtube.com
The Beatles: What Makes This Song Great?
YouTube video by Rick Beato
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Jim Januzzi @jimjanuzzi.bsky.social · 30/11/2024
www.tctmd.com/news/once-bu...
tctmd.com
Once Burned, Twice Shy, Cardiologists Ditch X for Bluesky
Though X (formerly Twitter) was once a place many cardiologists found community and opportunity, many are jumping ship.
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Parham Eshtehardi MD @cardioobdoc.bsky.social · 24/11/2024
Intensive lifestyle intervention, cardiac biomarkers & CV outcomes in diabetes: #LookAHEAD cardiac biomarker ancillary study #JACC #CardioSky #MedSky #EndoSky @jaccjournals.bsky.social @accintouch.bsky.social @jimjanuzzi.bsky.social www.jacc.org/doi/10.1016/...
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Art Schuermans @artschuermans.bsky.social · 21/11/2024
What does the circulating proteome teach us about common heart diseases? Thrilled to share our analysis identifying new biomarkers, drug targets, and prediction models for these conditions. Mentored (supremely) by @mchonig.bsky.social and @pnatarajanmd.bsky.social nature.com/articles/s44... (1/x)
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Anuradha Lala-Trindade (Anu Lala) MD @dranulala.bsky.social · 20/11/2024
Go figure🤷🏽‍♀️ May we use these platforms to inform, educate, connect & uplift - for the common good/evolution 🙏🏽❤️🫀🧘🏽‍♀️ @drmarthagulati.bsky.social @cardioobdoc.bsky.social @robmentz.bsky.social @jimjanuzzi.bsky.social @glaucomflecken.bsky.social #CardioSky #MedSky
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Dr Rajiv Sankaranarayanan @drrajivsankar.bsky.social · 19/11/2024
Welcome UK’s patientled HFcharity #BeatHF @carysbarton.bsky.social @poppybrooks.bsky.social @asanakpan.bsky.social @robmentz.bsky.social @dranulala.bsky.social @drmarthagulati.bsky.social @jimjanuzzi.bsky.social @shelleyzieroth.bsky.social @anastasiasmihaili.bsky.social @hancardiomd.bsky.social
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Jim Januzzi @jimjanuzzi.bsky.social · 17/11/2024
Hey everyone, another refugee from #Twitter here. Looking forward to engage with medically oriented folks. Glad to be here.
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