Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to a...

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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Kári Stefánsson, founder and long-time CEO of DeCode Genetics, has officially stepped down from his leadership role at the company he established nearly three decades ago. The announcement marks the e...

This cohort study uses whole-exome sequencing, genome-wide genotyping, baseline lipid levels, and incident events to assess the association of genetic predisposition to low-density lipoprotein cholest...

Site: The General Hospital Corporation At Mass General Brigham, we know it takes a surprising range of talented professionals to advance our mission—from doctors, nurses, business people and tech expe...

This clinical trial evaluates the efficacy of combining coronary artery calcium scoring with a prevention strategy to limit plaque progression in intermediate-risk patients with a family history of pr...

People of South Asian descent are more likely to be affected by heart disease, but their risks often go unnoticed. Researchers are looking to genetics to learn more and prevent early deaths.

MultiSTAAR provides a general and flexible statistical framework for functionally informed multi-trait rare variant analysis of biobank-scale sequencing studies by jointly analyzing multiple traits an...