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Robin Anger

@robinanger.bsky.social
144 followers 365 following 2 posts

Research Engineer (PhD) | Microbiologist & Microscopist Cryo-EM & Cryo-CLEM Specialist 🔬 Working at European Institute of Chemistry & Biology, France 🇫🇷 www.iecb.u-bordeaux.fr #cryoEM #cryoET #CryoCLEM #microsky

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Reposted by Robin Anger
Sholto David @sholtodavid.bsky.social · 20/09/2026
Today I'm posting a video about Neurodigitech LLC which has provided clearly photoshopped neurons to research teams that published these images in Nature, JBC, and more. A year after I uncovered this only one paper has been corrected. It's in Frontiers. youtu.be/4g_1_AWOVpI
youtu.be
Faked Images of Neurons in Major Journals
YouTube video by Sholto David
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Reposted by Robin Anger
ChimeraX @chimerax.ucsf.edu · 25/09/2026
Make natural language requests to ChimeraX with the new Pellaeon plugin developed by Yam Amir that works with many free and paid large language models. Get Pellaeon using ChimeraX menu Tools / More Tools.... cxtoolshed.rbvi.ucsf.edu/apps/chimera...
PAR1 molecular structure shown in ChimeraX using Pellaeon chat bot.
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Reposted by Robin Anger
Alex Noble @alexjamesnoble.bsky.social · 25/09/2026
We finally built what I've always wanted: A cryoEM papers database that is updated continually, searchable, and categorized! It's live right now at www.cryoarcana.com/cryoem-papers
CryoArcana CryoEM Papers Feed
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Zach Marin @zacsimile.bsky.social · 17/09/2026
Happy to share our publication on MicroClaw, an AI agent that turns natural language requests into operations on any microscope controlled by Micro-Manager: www.biorxiv.org/content/10.6.... The software is single-click installable (download and click install.bat) at github.com/Micro-Claw/m....
biorxiv.org
Microscope control with a natural language agent
Microscopy underpins modern biology, but acquiring high-quality data from complex experiments at scale remains challenging. Smart microscopy can standardize and automate data collection, but each expe...
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Reposted by Robin Anger
Ben Engel @cellarchlab.com · 18/06/2026
OK— so @phaips.vd.st & @florentwaltz.bsky.social have been testing extensively, and it's pretty clear that MissAlignment may be the best thing to happen to #TeamTomo in the last couple years. One issue: we have to re-process all our data again, hopefully for the last time 😅. Congrats and THANK YOU!!
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Reposted by Robin Anger
Nilesh Banavali @nilesh-banavali.bsky.social · 13/06/2026
Continuous recording beam image shift speeds up single particle and tomographic data collection. www.nature.com/articles/s41...
nature.com
Ultra-rapid cryo-EM data acquisition method enabled by continuous recording based beam image shift - Nature Communications
The authors report continuous recording beam-image shift (CR-BIS), a continuous recording strategy that overcomes camera delays to markedly accelerate cryo-EM data acquisition, improving throughput fo...
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Reposted by Robin Anger
RCSB Protein Data Bank @rcsbpdb.bsky.social · 08/06/2026
Watch the Tutorial: Introduction to Molecular Animation Learn how to use ChimeraX to create simple animations that can enrich your presentations, websites, and social media
pdb101.rcsb.org
PDB101: Tutorial: Introduction to Molecular Animation
PDB-101: Training, Outreach, and Education portal of RCSB PDB
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Structura Biotechnology @structurabio.bsky.social · 02/06/2026
For years, the #cryoEM community viewed ~50 kDa as the practical lower size limit for SPA. This was challenged by Kim et al., who introduced the HR-HAIR method and demonstrated structure determination of proteins below 30 kDa using #CryoSPARC. Read more 👉 bit.ly/3RHMxAt
bit.ly
CryoSPARC | The Resolution Revolution Is Still Ongoing
High-Resolution Ab-Initio Reconstruction: Extending Cryo-EM to Smaller Particles with CryoSPARC™
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Reposted by Robin Anger
Ben Cooper @bfcoop.bsky.social · 02/06/2026
It's a small project, but hopefully useful for others running RELION jobs. GitHub: github.com/bfcoop/relio... Feedback and feature suggestions are very welcome! #CryoEM #RELION #StructuralBiology #OpenSource
github.com
GitHub - bfcoop/relion_tracker: Track metrics from RELION optimiser STAR files directly in the terminal.
Track metrics from RELION optimiser STAR files directly in the terminal. - bfcoop/relion_tracker
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Reposted by Robin Anger
Ali Shaib @alishaib.bsky.social · 01/06/2026
Hello #world, meet 1,000× Expansion Microscopy. A small gel would grow to the size of an Olympic swimming pool, while amino-acid-scale distances become visible with ordinary light microscopy. Led by Helena Hu from @eboyden3.bsky.social's lab, in collab with us. Story: www.biorxiv.org/content/10.6...
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Science Magazine @science.org · 28/05/2026
Researchers have identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation. scim.ag/4nTQ3nq
How animals sense Earth’s magnetic field is one of biology’s enduring mysteries. Researchers have now identified superparamagnetic macrophages in the livers of rock pigeons (Columba livia) to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation.

Photo: Andreas Teichmann/laif/Redux
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Reese Richardson @reeserichardson.bsky.social · 28/05/2026
TL;DR: We've identified more than 100 cases of apparent manipulation in Thermo Fisher Scientific's antibody verification data. @sholtodavid.bsky.social @johanduchene.bsky.social reeserichardson.blog/2026/05/28/h...
reeserichardson.blog
How much of Thermo Fisher’s antibody data has been manipulated?
We’ve documented more than 100 instances of apparent data manipulation in Thermo’s catalog
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Robin Anger @robinanger.bsky.social · 26/05/2026
Don't ignore the "contaminants" on your grids ! We noticed this filament while solving the S. sanguinis T4P structure during my PhD. It turned out to be an incredible eDNA-protease assembly: literally a suspension bridge of proteins & DNA ! 🌉 Happy to finally share this story. #CryoEM #Microbiology
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Reposted by Robin Anger
Ariane Briegel @arianebriegel.bsky.social · 08/05/2026
Exciting times for our lab- recent developments in cryoET tools and workflows now allow us apply these to study microbes in the host context. #teamtomo www.sciencedirect.com/science/arti...
sciencedirect.com
Beyond resolution: Cryo-electron tomography of microbial nanomachines in native host context
Cryo-electron tomography (cryo-ET) has revolutionized visualization of bacterial nanomachines by revealing molecular structures in situ under near-nat…
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Reposted by Robin Anger
Gabriel Oka @okagu.bsky.social · 11/05/2026
Happy to share our new bioRxiv preprint: “To Kill or not to Kill: A Conserved Trans-Intoxication Protection Factor Blocks X-T4SS-Mediated Fratricide through Interaction with VirB5” www.biorxiv.org/content/10.6...
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SBGrid Consortium @sbgrid.bsky.social · 06/05/2026
New Title Alert: AF3Complex- is a model equipped with the same improvements as AF2Complex, along with a novel method for excluding ligands, built on AlphaFold 3. Learn more here: buff.ly/GPEgFSF #SBGrid #Software #Predictions
buff.ly
GitHub - Jfeldman34/AF3Complex
Contribute to Jfeldman34/AF3Complex development by creating an account on GitHub.
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Rémi Fronzes @fronzeslab.bsky.social · 28/04/2026
Still possible to register for the 14th Young Scientists' Symposium! 📅 4-5 June 2026 @iecb.bsky.social @univbordeaux.bsky.social Fantastic lineup of keynote speakers. @marionjasnin.bsky.social @amjjbonvin.bsky.social @olallalab.bsky.social
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Young Scientists' Symposium @yss-iecb.bsky.social · 15/04/2026
📢 Les inscriptions au Young Scientists' Symposium 2026 sont désormais ouvertes ! Pensez à vous inscrire et à diffuser l’information autour de vous 👇 Inscriptions : bit.ly/3OiYTxG Modèle d'abstract pour les présentations orales et/ou posters : lnkd.in/e2x8KJMG
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ChimeraX @chimerax.ucsf.edu · 24/02/2026
The new ChimeraX CubeNTube plugin allows erasing parts of maps using cube, cylinder, and custom shapes and has undo. Created by Tamino Cairoli. Available from ChimeraX menu Tools / More Tools....
ChimeraX screenshot showing CubeNTube plugin.
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Reposted by Robin Anger
Hanjin Liu @liu-hanjin.bsky.social · 22/02/2026
Since last year, I've been making a RELION GUI that supports viewing, navigating and running jobs in a way completely compatible with the original RELION pipeline. Now it's working nicely for both SPA and tomography! Please try it out - github.com/hanjinliu/hi...
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Rémi Fronzes @fronzeslab.bsky.social · 13/12/2025
🔬 Just out in @NatureComms! Using cryo-CLEM and cryo-ET, we reveal the unique ultrastructure of dopaminergic varicosities in the striatum. Amazing collaboration with @davip-bdx.bsky.social and Etienne Herzog @iins-bordeaux.bsky.social Congratulations to Paul and Robin for this fantastic work! 🎉
nature.com
Cryo-correlative light and electron tomography of dopaminergic axonal varicosities reveals non-synaptic modulation of cortico-striatal synapses - Nature Communications
The basic features of dopamine release sites are still largely unknown. Here, the authors determine the ultrastructure of fluorescent dopaminergic and glutamatergic synaptosomes in mouse striatum usin...
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Rémi Fronzes @fronzeslab.bsky.social · 24/11/2025
Very happy to share our work on lipopolysaccharide assembly by the Lpt complex, published today in @natcomms.nature.com Fantastic collaboration with @raffaeleieva.bsky.social l and t @pstansfeld.bsky.social Congrats to all authors, especially Haoxiang, Axel & Violette 🔗 doi.org/10.1038/s414...
doi.org
Structural basis of lipopolysaccharide assembly by the outer membrane translocon holo-complex - Nature Communications
The asymmetric distribution of lipopolysaccharide (LPS) on the surface of the bacterial outer membrane is essential and crucial for antibiotic resistance. Here, authors characterize the LPS translocon...
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Rémi Fronzes @fronzeslab.bsky.social · 21/11/2025
Our latest T7SS study is now out in Science Advances! We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery. www.science.org/doi/10.1126/...
science.org
A ubiquitin-like protein controls assembly of a bacterial type VIIb secretion system
Cryo-EM structure reveals how a ubiquitin-like protein orchestrates assembly of a bacterial weapon system.
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Guenter Resch @nexperion.net · 23/09/2025
Happy to announce "Technical Innovations Using #SerialEM: A Community Meeting", a new format of hybrid meeting David Mastronarde and I are organizing in April 2026. For more info, a preliminary list of speakers, pre-registration etc. visit www.nexperion.net/semcm2026
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Reposted by Robin Anger
Ben Engel @cellarchlab.com · 07/05/2025
“The Website” is here! It can be intimidating getting into analysis of #CryoET data, and software is evolving all the time👩‍💻🚀. @phaips.vd.st & @florentwaltz.bsky.social put our lab’s workflows into an online guide. We hope this helps lower the bar to joining #TeamTomo. Feedback much appreciated! 🧪🧶🧬🔬
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Reposted by Robin Anger
Dawid Zyla @dzyla.bsky.social · 27/04/2025
1/5: Over the last few months, I have been working on an update for the #FollowRelionGracefully dashboard, which offers improved real-time job previews for #cryoEM #Relion jobs.
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Lorenz Lamm @lorenzlamm.bsky.social · 25/04/2025
🦠🧠 MemBrain update! 🧠🦠 We’ve updated our preprint! It now covers the full MemBrain v2 pipeline for end-to-end membrane analysis in #CryoET: segmentation, particle picking, and spatial statistics. 🔗 Preprint: doi.org/10.1101/2024... 🔗 Code: github.com/CellArchLab/... 🧵(1/6) #TeamTomo
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Reposted by Robin Anger
Ben Engel @cellarchlab.com · 20/03/2025
We're on the cover of @science.org this week. Awesome work by @florentwaltz.bsky.social. #CryoET is reaching crazy resolutions inside cells, and this is just the beginning. Fantastic interpretation of the proton motive force by @verenaresch.bsky.social. Always a pleasure making #SciArt with you!🧪🧶🧬🌾
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Reposted by Robin Anger
ChimeraX @chimerax.ucsf.edu · 17/03/2025
ChimeraX can be used to find pockets and cavities in protein structures using the Find Cavities tool or kvfinder command. This feature is available in daily builds from 10 March 2025 or later.
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Reposted by Robin Anger
cryoEM papers @cryoempapers.bsky.social · 14/03/2025
AreTomoLive: Automated reconstruction of comprehensively-corrected and denoised cryo-electron tomograms in real-time and at high throughput www.biorxiv.org/content/10.1101/2025.03.11.642690v1 #cryoEM
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Rémi Fronzes @fronzeslab.bsky.social · 07/03/2025
Stand up for science in Bordeaux
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cryoEM papers @cryoempapers.bsky.social · 20/02/2025
Cryo-iCLEM: Cryo correlative light and electron microscopy with immersion objectives pubmed.ncbi.nlm.nih.gov/39971020/ #cryoEM
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IMP @impvienna.bsky.social · 12/02/2025
🔬Our @haselbachlab.bsky.social with Pavol Harar have developed ‘FakET’! The new method creates ‘fake’ electron microscopy images to train AI, reducing manual work in particle identification. Read the full story: www.imp.ac.at/news/article... @viennabiocenter.bsky.social #AI #cryoem #microscopy
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Carol Willing @willingc.bsky.social · 13/02/2025
Are you using @napari.org or want to learn more? I've curated a list of videos about napari and its uses on YouTube. If I missed a video, please let me know. www.youtube.com/playlist?lis...
youtube.com
napari - scientific image viewer - YouTube
napari (https://napari.org) is a fast, interactive viewer for multi-dimensional images in Python. Napari is a Python library for n-dimensional image visualis...
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Constantin Pape @cppape.bsky.social · 12/02/2025
After a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool. www.nature.com/articles/s41...
Improvements in LM (top) and EM (bottom) of our micro-sam model (finetuned) compared to the default SAM model.
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Structural Biology Communications @actacrystf.iucr.org · 11/02/2025
CryoCrane, a visualization tool for cryo-EM screening data, aims to provide an intuitive way to visualize micrographs and to speed up data analysis. #CryoEM #SampleOptimization #GridScreening doi.org/10.1107/S205...
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Paul Lapios 🧘‍♂️ @paulosh.bsky.social · 12/02/2025
Very happy to share our last preprint where we investigated the vesicular organization of dopamine hub synapses with cryo-CLEM. It is a brain structure that emerges as an important regulator of striatal activity. Many thanks to David Perrais, Etienne Herzog and the lab of @fronzeslab.bsky.social !
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STCmicrobeblog @stcmicrobeblog.bsky.social · 05/02/2025
@stevestuwill.bsky.social you posted on 𝕏 on Dec 5, 2020 this stunning video - why not repeat on 🔵bsky ? (sorry, I did)... "Time-lapse footage of a vampire amoeba: a microscopic organism that feeds on algal cells by breaking through their cell walls and sucking out their insides." #ProtistsOnSky
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Benedikt Wimmer @bwmr.net · 06/02/2025
Hey #teamtomo, if you often find yourself using the excellent membrain-seg from @lorenzlamm.bsky.social et al., you might find my napari plugin "napari-segselect" useful. Let's say your tomogram contains the edges of two bacterial cells, each with a membrane and cell wall:
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camnowell.bsky.social @camnowell.bsky.social · 05/02/2025
Answering the call of @haesleinhuepf.bsky.social, Christian Tischer, Pete Bankhead, @kbias.bsky.social @bethcimini.bsky.social My Fiji training notes are now FAIR. All online in an open format to download and use for teaching and training. All in Google Doc or PDF formats bit.ly/4hkfEBF
bit.ly
Home
This site contains the complete version of the Fiji Training Manual that is written and maintained by Cameron Nowell of the Monash Institue of Pharmaceutical Science. This manual is provided under the...
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Nature @nature.com · 29/01/2025
DeepSeek's open AI model is giving scientists worldwide the opportunity to train custom reasoning models designed to solve problems in their disciplines. go.nature.com/4azXz07
go.nature.com
Scientists flock to DeepSeek: how they’re using the blockbuster AI model
Researchers are testing how well the open model can perform scientific tasks — in topics from mathematics to cognitive neuroscience.
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Rémi Fronzes @fronzeslab.bsky.social · 29/01/2025
I am starting to assemble a starter pack with past and current members of our institute @iecb.bsky.social Send me a message if you wish to be included. go.bsky.app/L86XUk1
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Reposted by Robin Anger
Science Magazine @science.org · 17/01/2025
An #AI model created to design proteins simulates 500 million years of protein evolution in developing a previously unknown bright fluorescent protein. Learn more in a new Science study: scim.ag/40l2z3J
RESEARCH ARTICLE Simulating 500 million years of evolution with a language model.

Figure 1E, shown here, displays unconditional generations from ESM3 98B (colored by sequence identity to the nearest sequence in the training set), embedded by ESM3, and projected by UMAP alongside randomly sampled sequences from UniProt (in gray). Generations are diverse, high quality, and cover the distribution of natural sequences.
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Rémi Fronzes @fronzeslab.bsky.social · 26/01/2025
We are very pleased to share our latest preprint on the architecture of the membrane complex of the type 7 secretion system involved in bacterial competition in B. subtilis. #CryoEM #microsky
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SBGrid Consortium @sbgrid.bsky.social · 23/01/2025
In case you missed our first webinar of 2025, it is now available. Lorenz Lamm from MUDS - Munich School for Data Science presented MemBrainv2- an end-to-end tool for the analysis of membranes in cryo-electron tomography. buff.ly/4hutFwf #SBGridwebinars #ScienceMatters
buff.ly
MemBrainv2
SBGrid webinars are hosted with partial support from the NIH R25 Continuing Education for Structural Biology Mentors #GM151273, in collaboration with Co-PI J...
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Nature @nature.com · 13/01/2025
A decade in, expansion microscopy is unlocking insights across biology and medicine go.nature.com/4adlNgg
go.nature.com
‘Expansion microscopy’ turns ten: how a tissue-swelling method brought super-resolution imaging to the masses
A decade in, expansion microscopy is unlocking insights across biology and medicine.
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Cascales Lab @cascaleslab.bsky.social · 18/01/2025
We have an open PhD position to work on bacterial secretion systems. Please RT, write us or apply through the CNRS job portal: t.co/HxX23Od1oa
t.co
https://emploi.cnrs.fr/Offres/Doctorant/UMR7255-ERICAS-004/Default.aspx?lang=EN
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