La plateforme de cryo-microscopie électronique à l’Institut européen de chimie et biologie (IECB) est renforcée par l’acquisition de deux nouveaux microscopes, Glacios 2 et Talos L120. Ces équipements de pointe offrent aux chercheurs une capacité unique pour explorer l’architecture moléculaire et cellulaire avec une précision inédite, positionnant Bordeaux comme un acteur majeur dans ce domaine en France.

Uncontrolled activation of the rat sarcoma (RAS)–extracellular signal–regulated kinase (ERK) pathway drives tumor growth, often because of oncogenic BRAF mutations. BRAF regulation, involving monomeri...

Eucaryotic EndoU are endoribonucleases that require calcium ions to cleave RNA substrates. Here, the authors solved the structure of calcium-activated human EndoU and proposed a structural model for U...

Bacterial films are a hazard throughout the healthcare system, and as antibiotic resistance increases there is an even greater imperative...

Chitin is the most important nitrogen-containing polysaccharide found on Earth. This polysaccharide is a polymer of an N-acetylglucosamine and it is a…

Pathogenic fungal and bacterial cells are enveloped within a cell wall, a molecular barrier at their cell surface, and a critical architecture that constantly evolves during pathogenesis. Understandin...

Bacterial films are a hazard throughout the healthcare system, and as antibiotic resistance increases there is an even greater imperative...

Nature Communications - This study reveals how the intrinsically disordered region of eIF4B governs its transition from monomers to oligomers and condensed droplets, providing key insights into how...

imageimageThe bacterial hexameric ATPases RadA and ComM mediate DNA branch migration in the homologous recombination pathway of genetic transformation in distinct bacterial species. This study offers ...

Bacteria can synthesize and secrete cellulosic polymers using membrane-associated multiprotein complexes consisting of cellulose synthases and accessory subunits. Here, Anso et al. use cryogenic elect...