Rémi Fronzes @fronzeslab.bsky.social · 29/09/2026CryoFIB SEM installed at the @bic-bordeaux.bsky.social 🍾🎉🍾🎉 3439
Reposted by Rémi FronzesCarl Zimmer @carlzimmer.com · 27/09/2026Four days ago, a scientist was surprised by the news that Anthropic discovered new virus genes for making DNA. He says he’s been studying them for years—and feeding his data to Anthropic’s AI as part of his own research. Coincidence? Here’s my story. nyti.ms/3VSWaycnyti.msDid Anthropic’s A.I. Really Make a Scientific Discovery on Its Own? (Gift Article)An expert at the University of Copenhagen said his team had been sharing its research with the company’s A.I. model, Claude, and that its new finding matched their work. 892115864
Reposted by Rémi FronzesRasmus Jensen @rasmusjensen.bsky.social · 25/09/2026🎉 Out today in Cell: the paper I've been looking forward to sharing for a long time 🎉 We used cryo-ET to find a molecular machine nobody knew existed on the surface of a minimal bacterium, and worked out what it does. 🧵(1/7) #TeamTomo #cryoET 1023190
Rémi Fronzes @fronzeslab.bsky.social · 24/09/2026Indeed.journals.asm.orgAs a component of aseptic technique, Bunsen burners do not universally decrease deposition of microbe-containing particles | Microbiology SpectrumThe ability to manipulate and control microbial presence in built environments is imperative to research and medicine. The lack of documented evidence relating Bunsen burner use and airborne contamina... 010
Reposted by Rémi FronzesCathy Spangler @cathyspangler.bsky.social · 22/09/2026I'm excited to share our new preprint, where we show that fine-tuning gold nanoparticle conjugation to different Fab structural elements can produce powerful, rigidly coupled, labeling tools for in-situ cryo-ET. Take a look if you want to see an AuNP in an EM map!🔬🧠 www.biorxiv.org/content/10.6... 14922
Reposted by Rémi FronzesElia Stahl @eliastahl.bsky.social · 21/09/2026Next speaker for our @iecb.bsky.social seminar is Kira Gysel from @au.dk. This week Friday (25.09.2026, 11:00 AM) at the IECB auditorium. "Decoding the carbohydrate language of plant–microbe interactions" Open to the full scientific community of @univbordeaux.bsky.social @deptse-ub.bsky.social 164
Rémi Fronzes @fronzeslab.bsky.social · 20/09/2026yesterday was another perfect day for a little stroll in the mountains. 050
Reposted by Rémi FronzesAlexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 19/09/2026Oh mais ça a l'air pas mal du tout ça. Vivement que Emmy, Mistral et le CNRS nous propose la même chose 😬😭 #ESR #AI www.anthropic.com/research/cla...anthropic.comHow Claude is uplifting biomolecular modelingAnthropic is an AI safety and research company that's working to build reliable, interpretable, and steerable AI systems. 272
Reposted by Rémi FronzesSéamus Holden 🔬🦠🧫 @seamusholden.bsky.social · 18/09/2026Really impressing MINFLUX tracking of molecular motors www.nature.com/articles/s41... #bioimagingnature.comCharacterizing dynamics of productive dynein stepping by MINFLUX - Nature Structural & Molecular BiologySlivka et al. track dynein’s microtubule-binding domain with minimal fluorescence photon flux, revealing transient backward ‘dips’ before steps. These dips represent microtubule release upon ATP bindi... 0168
Rémi Fronzes @fronzeslab.bsky.social · 18/09/2026@cnrs banned Claude from our labs. We are not allowed to use it and cannot pay access to these ressources with research grants. This is a NONSENSE. We are wasting time and money. And above all undermine our competitiveness 2110
Rémi Fronzes @fronzeslab.bsky.social · 15/09/2026Using Claude science for a « in silico » structural biology project. Definitely very useful to automate processing pipelines and data processing. But makes a lot of errors and is going in the wrong direction if not carefully guided and monitored. To be handled with great care 0102
Reposted by Rémi FronzesSergey Ovchinnikov @sokrypton.org · 14/09/2026Finally a more intuitaive way to learn pLDDT/pAE? 😎 sokrypton.github.io/protein_figh... (Character idea from @hannes-stark.bsky.social & Alex Waldherr) 727697
Rémi Fronzes @fronzeslab.bsky.social · 13/09/2026Here is the problem with IA leadership. One day they say something that seems reasonable (regulation, safeguards), and the next something completely nuts… It shows that these people cannot be trusted to manage such a sensitive technology. 120
Rémi Fronzes @fronzeslab.bsky.social · 12/09/2026Glaçant…lemonde.frIA : le patron d’Anthropic, Dario Amodei, appelle à ralentir la vitesse de développement de l’intelligence artificielle avant que des agents soient « capables de prendre le contrôle d’internet »Le message publié samedi par Dario Amodei survient quelques jours après qu’un chercheur d’Anthropic, Jacob Coxon, a annoncé quitter la start-up californienne, l’accusant de minimiser le risque existen... 200
Reposted by Rémi FronzesChristophe Zimmer @chzimmer.bsky.social · 10/09/2026Can you tell how an antibiotic kills bacteria just by watching them under a regular microscope — without any dyes ? Yes, it turns out, at least if you are a deep neural net. 12316
Reposted by Rémi FronzesBen Engel @cellarchlab.com · 08/09/2026MemBrain v2 is on @natmethods.nature.com now? I never had a @biorxivpreprint.bsky.social with 164 citations before😅 ...Which is also to say: Thank you to the amazing #TeamTomo community, many of whom not only beta tested, but also contributed diverse training data. This one belongs to all of us! 🤗🔬🧪 011027
Rémi Fronzes @fronzeslab.bsky.social · 07/09/2026Met some locals during my trail run this weekend. They were not impressed by my pace. 1151
Reposted by Rémi FronzesJeremy Berg @jeremymberg.bsky.social · 05/09/2026Freddy would have been 80 today. What a great talent. www.youtube.com/watch?v=frdB...youtube.comQueen - Live Aid 1985 Full ConcertYouTube video by uploader.JP8 37014
Rémi Fronzes @fronzeslab.bsky.social · 01/09/2026@krastevalab.bsky.social and @remaut-lab.bsky.social will probably enjoy this one. 060
Reposted by Rémi FronzesAlex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 31/08/2026Our new paper with @ckellison.bsky.social. is finally out! We identify an ancient and widely conserved mechanism that promotes initiation of fiber polymerization in type IV pili and type II secretion systems.pnas.orgβ-strand addition within tip initiation complexes licenses assembly of diverse type IV filaments | PNASPilC/PilY1 proteins are tip-located adhesins of type IV pili (T4P) that are critical for T4P function in diverse behaviors including twitching moti... 57924
Rémi Fronzes @fronzeslab.bsky.social · 30/08/2026Or me, if I were still at the bench in the lab 😬 050
Reposted by Rémi FronzesGabriel Oka @okagu.bsky.social · 28/08/2026🧬 Happy to share our new preprint: ppigFinder, a desktop tool integrating bacterial genome analysis with large-scale AlphaFold 3 protein–protein interaction screening. We showcase it by exploring the VirD4 interactome of Xanthomonas citri. 💻 github.com/leepusp/ppig...github.comGitHub - leepusp/ppigfinderContribute to leepusp/ppigfinder development by creating an account on GitHub. 0114
Rémi Fronzes @fronzeslab.bsky.social · 26/08/2026This is a massive scandal... We should all check our antibody stocks and if the validation data appears faked/manipulated, we should ask for a refund. That's the least these companies could do. 130
Reposted by Rémi FronzesTracy Palmer @proftracypalmer.bsky.social · 25/08/2026Happy to see this work preprinted! Only our second foray into the mycobacterial T7SS 0187
Rémi Fronzes @fronzeslab.bsky.social · 25/08/2026No cheating. Share the last photo of the sky from your photo roll 200
Rémi Fronzes @fronzeslab.bsky.social · 23/08/2026Guess what I’m going to do with that ! 🤤🤤🤤 #simplepleasures 170
Reposted by Rémi FronzesMelaine Le Roy @subfossilguy.bsky.social · 22/08/2026Unprecedented... 70 days! France has just ended yesterday the longest series above the norm (1991-2020) ever measured! 🥵 Four heat waves—and another one before that, in May… That’s what our future will look like—only worse! 😱 📈 via Nicolas Berrod 625687
Rémi Fronzes @fronzeslab.bsky.social · 21/08/2026Super série d’émissions ! Extrêmement intéressant. J’ai binge-écouté tous les podcasts. 1192
Reposted by Rémi Fronzesanna brogan @apbrogan.bsky.social · 18/08/2026This is now published! For those interested in microbial mechanotransduction: www.cell.com/current-biol...cell.comMicrobial GAIN domains undergo autoproteolysis and enable release of diverse cell-surface-associated proteinsBrogan and Rudner report the identification of a microbial autoproteolytic domain that is structurally homologous to the GAIN domain of eukaryotic adhesion GPCRs. Rather than participating in transmem... 13921
Rémi Fronzes @fronzeslab.bsky.social · 19/08/2026Nice trail run to the pic du Sauvegarde near Luchon this morning. 1600 D+ 18km. 070
Reposted by Rémi FronzesNature Microbiology @natmicrobiol.nature.com · 17/08/2026Out Now! Quinone-transporting filaments expand bioenergetic capacity in Gram-positive Bacillota #MicroSkygo.nature.comQuinone-transporting filaments expand bioenergetic capacity in Gram-positive BacillotaNature Microbiology, Published online: 17 August 2026; doi:10.1038/s41564-026-02450-zBacillus subtilis Ncp and NADH dehydrogenase form tube-like filaments with phospholipid-lined chambers that associate with quinones, which can expand bioenergetic capacity and support respiratory electron transfer. 03210
Reposted by Rémi FronzesÁkos T Kovács @evolvedbiofilm.bsky.social · 15/08/2026Constitutive, endogenous, fluorescent membrane reporters for dynamic cell cycle analysis in Bacillus subtilis in Appl Environ Microbiol from Stephen Jacobson, Dan Kearns journals.asm.org/doi/10.1128/...journals.asm.orgConstitutive, endogenous, fluorescent membrane reporters for dynamic cell cycle analysis in Bacillus subtilis | Applied and Environmental MicrobiologyBacterial cells are fully divided when the new membrane separates the cytoplasm of each daughter. Reproducible staining of bacterial membranes with exogenous labels for fluorescence microscopy can be ... 063
Rémi Fronzes @fronzeslab.bsky.social · 11/08/2026Ça fait des millénaires que les éclipses solaires fascinent l’humanité !!! Mais bon… Qui aurait pu prévoir ? 140
Rémi Fronzes @fronzeslab.bsky.social · 04/08/2026Donc ? on essaie de faire quelque chose ou on continue à regarder ailleurs ? #dontlookuplemonde.frJuillet 2026 a été le mois le plus chaud jamais enregistré en France depuis le début des mesures, en 1900Le mois dernier a aussi été le troisième mois de juillet le moins pluvieux dans le pays, provoquant une sécheresse des sols record, avec des conséquences importantes sur l’agriculture et favorisant le... 010
Reposted by Rémi FronzesKate Beckham @kshbeckham.bsky.social · 03/08/2026Happy to share our recent story on the Type VII secretion system. Here were present new insights into the regulation of secretion mediated by the central pore. Thanks to all authors involved in the work. 🙂 14920
Reposted by Rémi Fronzesc0nc0rdance @c0nc0rdance.bsky.social · 01/08/2026The headlines are still covering the cyclosporiasis outbreak from lettuce, but let's talk about a different summer, long ago. The headlines in Bavaria would have called it "summer diarrhea" & it was killing babies. Enter our hero, Professor Theodor Escherich of the Julius Hospital, Würzburg. 321990
Reposted by Rémi FronzesLe Canard enchaîné @lecanardenchaine.fr · 01/08/2026En février 2024, Gabriel Attal n’était pas seul aux manettes quand le budget de la sécurité civile a été tronçonné. Thomas Cazenave, l’actuel maire de Bordeaux, était sous-ministre des Comptes publics. f.mtr.coolIncendies et manque de Canadair : Emmanuel Macron a empilé les promesses fumeuses | Le Canard enchaînéEn 2022, le président de la République avait annoncé le renouvellement complet de la flotte plus que vieillissante de Canadair, mais les commandes de bombardiers…… 10251153
Rémi Fronzes @fronzeslab.bsky.social · 01/08/2026Yes, it is shocking. I confirm. What we are experiencing is not a « normal » summer. 020
Reposted by Rémi FronzesChristophe Cassou @cassouman40.bsky.social · 31/07/2026Nous ne sommes ni en stress ni en crise climatique mais en #FailliteClimatique. Les incendies 2026 actent la #FaillitePyrique qui impose de sortir des gestions de crise devenue quasi-annuelle mais de gérer le dépôt de bilan! 🙏@franceculture.fr pour cette matinale!👇 www.radiofrance.fr/francecultur...radiofrance.frChristophe Cassou face à l’été cataclysmique : vivre ce que l’on a passé sa vie à annoncerLes incendies et les canicules à répétition depuis la fin du printemps ne sont qu’un avant-goût de ce nous vivrons dans quelques étés. C’est ce dont les scientifiques nous alertent depuis longtemps. C... 13469281
Reposted by Rémi FronzesJCB @baretjc.bsky.social · 30/07/2026www.gov.uk/government/n...gov.ukJoint Statement by the Ministers of Foreign Affairs of the United Kingdom of Great Britain and Northern Ireland and the Kingdom of Spain on Wildfires and Action on Climate ChangeThe UK and Spain agreed that the climate crisis is an urgent policy priority and committed to co-leading the green transition, strengthening clean energy cooperation and advancing international climat... 121
Rémi Fronzes @fronzeslab.bsky.social · 30/07/2026Back home. The fires are not fully contained yet, but what will stay with me is the solidarity, for the firefighters and for everyone who was evacuated and suddenly found themselves with nothing. Happy to se that the word “fraternité” in our motto still means something. 160
Rémi Fronzes @fronzeslab.bsky.social · 28/07/2026Today is going to be decisive. After two relatively stable nights, the fire is going to be reactivated by the wind and heatwave. Very much impressed by the strength and dedication of our firemen/women!!! 030
Rémi Fronzes @fronzeslab.bsky.social · 26/07/2026For scale, the burnt zone now runs from Lacanau near the coast to Marcheprime, at the gates of Bordeaux. About 40 km, close to an hour by road. And it is still strong and moving southeast, straight towards the southwestern suburbs of the city. 250
Reposted by Rémi Fronzesabberior @abberior.rocks · 24/07/2026Tubulin (green) & #BILBO1 (magenta) in #Trypanosoma brucei. 3D MINFLUX shows BILBO1's nanoscale architecture at the flagellar pocket collar. More: Zelená et al., PLOS Biology (link in reply). Image: Mélanie Bonhivers (@mbonhivers.bsky.social), CNRS/Univ. Bordeaux #fluorescencefriday #MINFLUX 0105
Rémi Fronzes @fronzeslab.bsky.social · 24/07/2026What a mess… so sad to see all these very familiar places go up in flames. My thoughts are with the people who have lost their homes or workplaces, and with everyone evacuated overnight.theguardian.comFrance orders evacuation of Cap Ferret peninsula as wildfire spreads – Europe liveEvacuees have been told to leave the area before 10am, using hundreds of mobilised boats or the only road linking the area with the mainland 010
Rémi Fronzes @fronzeslab.bsky.social · 23/07/2026Four years after the megafires at La Teste and Landiras, Gironde is burning again. So far, 3,400 hectares between Saumos and Le Porge, around 20,000 people evacuated. All my thoughts to those directly affected, and huge admiration and thanks to our firefighters. Real heroes. 011