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Rémi Fronzes

@fronzeslab.bsky.social
3.3K followers 3.7K following 996 posts

🔬 CNRS Research Director, Bordeaux Structural biologist & microbiologist 🏃‍♂️ Runner & 🚴 Cyclist (mostly Velotaf) ⛰️ Mountain & nature lover 🏛️ Formerly at UCL/Birkbeck & Institut Pasteur 🦠 Trying to figure out how bacteria fight, defend & adapt

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Rémi Fronzes @fronzeslab.bsky.social · 29/09/2026
CryoFIB SEM installed at the @bic-bordeaux.bsky.social 🍾🎉🍾🎉
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Carl Zimmer @carlzimmer.com · 27/09/2026
Four days ago, a scientist was surprised by the news that Anthropic discovered new virus genes for making DNA. He says he’s been studying them for years—and feeding his data to Anthropic’s AI as part of his own research. Coincidence? Here’s my story. nyti.ms/3VSWayc
nyti.ms
Did Anthropic’s A.I. Really Make a Scientific Discovery on Its Own? (Gift Article)
An expert at the University of Copenhagen said his team had been sharing its research with the company’s A.I. model, Claude, and that its new finding matched their work.
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Rasmus Jensen @rasmusjensen.bsky.social · 25/09/2026
🎉 Out today in Cell: the paper I've been looking forward to sharing for a long time 🎉 We used cryo-ET to find a molecular machine nobody knew existed on the surface of a minimal bacterium, and worked out what it does. 🧵(1/7) #TeamTomo #cryoET
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Rémi Fronzes @fronzeslab.bsky.social · 24/09/2026
Indeed.
journals.asm.org
As a component of aseptic technique, Bunsen burners do not universally decrease deposition of microbe-containing particles | Microbiology Spectrum
The ability to manipulate and control microbial presence in built environments is imperative to research and medicine. The lack of documented evidence relating Bunsen burner use and airborne contamina...
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Cathy Spangler @cathyspangler.bsky.social · 22/09/2026
I'm excited to share our new preprint, where we show that fine-tuning gold nanoparticle conjugation to different Fab structural elements can produce powerful, rigidly coupled, labeling tools for in-situ cryo-ET. Take a look if you want to see an AuNP in an EM map!🔬🧠 www.biorxiv.org/content/10.6...
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Elia Stahl @eliastahl.bsky.social · 21/09/2026
Next speaker for our @iecb.bsky.social seminar is Kira Gysel from @au.dk. This week Friday (25.09.2026, 11:00 AM) at the IECB auditorium. "Decoding the carbohydrate language of plant–microbe interactions" Open to the full scientific community of @univbordeaux.bsky.social @deptse-ub.bsky.social
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Rémi Fronzes @fronzeslab.bsky.social · 20/09/2026
yesterday was another perfect day for a little stroll in the mountains.
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Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 19/09/2026
Oh mais ça a l'air pas mal du tout ça. Vivement que Emmy, Mistral et le CNRS nous propose la même chose 😬😭 #ESR #AI www.anthropic.com/research/cla...
anthropic.com
How Claude is uplifting biomolecular modeling
Anthropic is an AI safety and research company that's working to build reliable, interpretable, and steerable AI systems.
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Séamus Holden 🔬🦠🧫 @seamusholden.bsky.social · 18/09/2026
Really impressing MINFLUX tracking of molecular motors www.nature.com/articles/s41... #bioimaging
nature.com
Characterizing dynamics of productive dynein stepping by MINFLUX - Nature Structural & Molecular Biology
Slivka et al. track dynein’s microtubule-binding domain with minimal fluorescence photon flux, revealing transient backward ‘dips’ before steps. These dips represent microtubule release upon ATP bindi...
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Rémi Fronzes @fronzeslab.bsky.social · 18/09/2026
@cnrs banned Claude from our labs. We are not allowed to use it and cannot pay access to these ressources with research grants. This is a NONSENSE. We are wasting time and money. And above all undermine our competitiveness
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Rémi Fronzes @fronzeslab.bsky.social · 15/09/2026
Using Claude science for a « in silico » structural biology project. Definitely very useful to automate processing pipelines and data processing. But makes a lot of errors and is going in the wrong direction if not carefully guided and monitored. To be handled with great care
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Sergey Ovchinnikov @sokrypton.org · 14/09/2026
Finally a more intuitaive way to learn pLDDT/pAE? 😎 sokrypton.github.io/protein_figh... (Character idea from @hannes-stark.bsky.social & Alex Waldherr)
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Rémi Fronzes @fronzeslab.bsky.social · 13/09/2026
Here is the problem with IA leadership. One day they say something that seems reasonable (regulation, safeguards), and the next something completely nuts… It shows that these people cannot be trusted to manage such a sensitive technology.
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Rémi Fronzes @fronzeslab.bsky.social · 12/09/2026
Glaçant…
lemonde.fr
IA : le patron d’Anthropic, Dario Amodei, appelle à ralentir la vitesse de développement de l’intelligence artificielle avant que des agents soient « capables de prendre le contrôle d’internet »
Le message publié samedi par Dario Amodei survient quelques jours après qu’un chercheur d’Anthropic, Jacob Coxon, a annoncé quitter la start-up californienne, l’accusant de minimiser le risque existen...
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Christophe Zimmer @chzimmer.bsky.social · 10/09/2026
Can you tell how an antibiotic kills bacteria just by watching them under a regular microscope — without any dyes ? Yes, it turns out, at least if you are a deep neural net.
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Ben Engel @cellarchlab.com · 08/09/2026
MemBrain v2 is on @natmethods.nature.com now? I never had a @biorxivpreprint.bsky.social with 164 citations before😅 ...Which is also to say: Thank you to the amazing #TeamTomo community, many of whom not only beta tested, but also contributed diverse training data. This one belongs to all of us! 🤗🔬🧪
BioRxiv FTW
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Rémi Fronzes @fronzeslab.bsky.social · 07/09/2026
Met some locals during my trail run this weekend. They were not impressed by my pace.
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Jeremy Berg @jeremymberg.bsky.social · 05/09/2026
Freddy would have been 80 today. What a great talent. www.youtube.com/watch?v=frdB...
youtube.com
Queen - Live Aid 1985 Full Concert
YouTube video by uploader.JP8
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Rémi Fronzes @fronzeslab.bsky.social · 04/09/2026
François Jacob and Jacques Monod.
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Rémi Fronzes @fronzeslab.bsky.social · 01/09/2026
@krastevalab.bsky.social and @remaut-lab.bsky.social will probably enjoy this one.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 31/08/2026
Our new paper with @ckellison.bsky.social. is finally out! We identify an ancient and widely conserved mechanism that promotes initiation of fiber polymerization in type IV pili and type II secretion systems.
pnas.org
β-strand addition within tip initiation complexes licenses assembly of diverse type IV filaments | PNAS
PilC/PilY1 proteins are tip-located adhesins of type IV pili (T4P) that are critical for T4P function in diverse behaviors including twitching moti...
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Rémi Fronzes @fronzeslab.bsky.social · 30/08/2026
Or me, if I were still at the bench in the lab 😬
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Rémi Fronzes @fronzeslab.bsky.social · 30/08/2026
My kids cooking… 😂
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Gabriel Oka @okagu.bsky.social · 28/08/2026
🧬 Happy to share our new preprint: ppigFinder, a desktop tool integrating bacterial genome analysis with large-scale AlphaFold 3 protein–protein interaction screening. We showcase it by exploring the VirD4 interactome of Xanthomonas citri. 💻 github.com/leepusp/ppig...
github.com
GitHub - leepusp/ppigfinder
Contribute to leepusp/ppigfinder development by creating an account on GitHub.
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Rémi Fronzes @fronzeslab.bsky.social · 26/08/2026
This is a massive scandal... We should all check our antibody stocks and if the validation data appears faked/manipulated, we should ask for a refund. That's the least these companies could do.
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Tracy Palmer @proftracypalmer.bsky.social · 25/08/2026
Happy to see this work preprinted! Only our second foray into the mycobacterial T7SS
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Rémi Fronzes @fronzeslab.bsky.social · 25/08/2026
No cheating. Share the last photo of the sky from your photo roll
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Rémi Fronzes @fronzeslab.bsky.social · 23/08/2026
Guess what I’m going to do with that ! 🤤🤤🤤 #simplepleasures
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Melaine Le Roy @subfossilguy.bsky.social · 22/08/2026
Unprecedented... 70 days! France has just ended yesterday the longest series above the norm (1991-2020) ever measured! 🥵 Four heat waves—and another one before that, in May… That’s what our future will look like—only worse! 😱 📈 via Nicolas Berrod
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Rémi Fronzes @fronzeslab.bsky.social · 21/08/2026
💯
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Rémi Fronzes @fronzeslab.bsky.social · 21/08/2026
Super série d’émissions ! Extrêmement intéressant. J’ai binge-écouté tous les podcasts.
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anna brogan @apbrogan.bsky.social · 18/08/2026
This is now published! For those interested in microbial mechanotransduction: www.cell.com/current-biol...
cell.com
Microbial GAIN domains undergo autoproteolysis and enable release of diverse cell-surface-associated proteins
Brogan and Rudner report the identification of a microbial autoproteolytic domain that is structurally homologous to the GAIN domain of eukaryotic adhesion GPCRs. Rather than participating in transmem...
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Rémi Fronzes @fronzeslab.bsky.social · 19/08/2026
Nice trail run to the pic du Sauvegarde near Luchon this morning. 1600 D+ 18km.
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Nature Microbiology @natmicrobiol.nature.com · 17/08/2026
Out Now! Quinone-transporting filaments expand bioenergetic capacity in Gram-positive Bacillota #MicroSky
go.nature.com
Quinone-transporting filaments expand bioenergetic capacity in Gram-positive Bacillota
Nature Microbiology, Published online: 17 August 2026; doi:10.1038/s41564-026-02450-zBacillus subtilis Ncp and NADH dehydrogenase form tube-like filaments with phospholipid-lined chambers that associate with quinones, which can expand bioenergetic capacity and support respiratory electron transfer.
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Ákos T Kovács @evolvedbiofilm.bsky.social · 15/08/2026
Constitutive, endogenous, fluorescent membrane reporters for dynamic cell cycle analysis in Bacillus subtilis in Appl Environ Microbiol from Stephen Jacobson, Dan Kearns journals.asm.org/doi/10.1128/...
journals.asm.org
Constitutive, endogenous, fluorescent membrane reporters for dynamic cell cycle analysis in Bacillus subtilis | Applied and Environmental Microbiology
Bacterial cells are fully divided when the new membrane separates the cytoplasm of each daughter. Reproducible staining of bacterial membranes with exogenous labels for fluorescence microscopy can be ...
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Rémi Fronzes @fronzeslab.bsky.social · 11/08/2026
Ça fait des millénaires que les éclipses solaires fascinent l’humanité !!! Mais bon… Qui aurait pu prévoir ?
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Rémi Fronzes @fronzeslab.bsky.social · 04/08/2026
Donc ? on essaie de faire quelque chose ou on continue à regarder ailleurs ? #dontlookup
lemonde.fr
Juillet 2026 a été le mois le plus chaud jamais enregistré en France depuis le début des mesures, en 1900
Le mois dernier a aussi été le troisième mois de juillet le moins pluvieux dans le pays, provoquant une sécheresse des sols record, avec des conséquences importantes sur l’agriculture et favorisant le...
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Kate Beckham @kshbeckham.bsky.social · 03/08/2026
Happy to share our recent story on the Type VII secretion system. Here were present new insights into the regulation of secretion mediated by the central pore. Thanks to all authors involved in the work. 🙂
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c0nc0rdance @c0nc0rdance.bsky.social · 01/08/2026
The headlines are still covering the cyclosporiasis outbreak from lettuce, but let's talk about a different summer, long ago. The headlines in Bavaria would have called it "summer diarrhea" & it was killing babies. Enter our hero, Professor Theodor Escherich of the Julius Hospital, Würzburg.
Signed portrait of Theodor Escherich, MD (1857-1911). Dr. Escherich was a German-Austrian pediatrician, best known for his discovery of the Escherichia coli bacterium
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Le Canard enchaîné @lecanardenchaine.fr · 01/08/2026
En février 2024, Gabriel Attal n’était pas seul aux manettes quand le budget de la sécurité civile a été tronçonné. Thomas Cazenave, l’actuel maire de Bordeaux, était sous-ministre des Comptes publics. 
f.mtr.cool
Incendies et manque de Canadair : Emmanuel Macron a empilé les promesses fumeuses | Le Canard enchaîné
En 2022, le président de la République avait annoncé le renouvellement complet de la flotte plus que vieillissante de Canadair, mais les commandes de bombardiers……
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Rémi Fronzes @fronzeslab.bsky.social · 01/08/2026
Yes, it is shocking. I confirm. What we are experiencing is not a « normal » summer.
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Christophe Cassou @cassouman40.bsky.social · 31/07/2026
Nous ne sommes ni en stress ni en crise climatique mais en #FailliteClimatique. Les incendies 2026 actent la #FaillitePyrique qui impose de sortir des gestions de crise devenue quasi-annuelle mais de gérer le dépôt de bilan! 🙏@franceculture.fr pour cette matinale!👇 www.radiofrance.fr/francecultur...
radiofrance.fr
Christophe Cassou face à l’été cataclysmique : vivre ce que l’on a passé sa vie à annoncer
Les incendies et les canicules à répétition depuis la fin du printemps ne sont qu’un avant-goût de ce nous vivrons dans quelques étés. C’est ce dont les scientifiques nous alertent depuis longtemps. C...
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JCB @baretjc.bsky.social · 30/07/2026
www.gov.uk/government/n...
gov.uk
Joint Statement by the Ministers of Foreign Affairs of the United Kingdom of Great Britain and Northern Ireland and the Kingdom of Spain on Wildfires and Action on Climate Change
The UK and Spain agreed that the climate crisis is an urgent policy priority and committed to co-leading the green transition, strengthening clean energy cooperation and advancing international climat...
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Rémi Fronzes @fronzeslab.bsky.social · 30/07/2026
Back home. The fires are not fully contained yet, but what will stay with me is the solidarity, for the firefighters and for everyone who was evacuated and suddenly found themselves with nothing. Happy to se that the word “fraternité” in our motto still means something.
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Rémi Fronzes @fronzeslab.bsky.social · 28/07/2026
Today is going to be decisive. After two relatively stable nights, the fire is going to be reactivated by the wind and heatwave. Very much impressed by the strength and dedication of our firemen/women!!!
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Rémi Fronzes @fronzeslab.bsky.social · 26/07/2026
For scale, the burnt zone now runs from Lacanau near the coast to Marcheprime, at the gates of Bordeaux. About 40 km, close to an hour by road. And it is still strong and moving southeast, straight towards the southwestern suburbs of the city.
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Rémi Fronzes @fronzeslab.bsky.social · 25/07/2026
Evacuating… what a mess
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abberior @abberior.rocks · 24/07/2026
Tubulin (green) & #BILBO1 (magenta) in #Trypanosoma brucei. 3D MINFLUX shows BILBO1's nanoscale architecture at the flagellar pocket collar. More: Zelená et al., PLOS Biology (link in reply). Image: Mélanie Bonhivers (@mbonhivers.bsky.social), CNRS/Univ. Bordeaux #fluorescencefriday #MINFLUX
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Rémi Fronzes @fronzeslab.bsky.social · 24/07/2026
What a mess… so sad to see all these very familiar places go up in flames. My thoughts are with the people who have lost their homes or workplaces, and with everyone evacuated overnight.
theguardian.com
France orders evacuation of Cap Ferret peninsula as wildfire spreads – Europe live
Evacuees have been told to leave the area before 10am, using hundreds of mobilised boats or the only road linking the area with the mainland
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Rémi Fronzes @fronzeslab.bsky.social · 23/07/2026
Four years after the megafires at La Teste and Landiras, Gironde is burning again. So far, 3,400 hectares between Saumos and Le Porge, around 20,000 people evacuated. All my thoughts to those directly affected, and huge admiration and thanks to our firefighters. Real heroes.
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