Reposted by Phill StansfeldBiochemical Society @biochemsoc.bsky.social · 09/04/2026Visiting from Sydney, we were honoured to present Renae Ryan with the 2025 International Award today! Renae closed out the Membrane Proteins Conference with her fascinating insights into the twisted link between glutamate transporters and Episodic Ataxia. 1133
Reposted by Phill StansfeldBiochemical Society @biochemsoc.bsky.social · 07/04/2026Congratulations to Doryen Bubeck who was presented with the 2026 GlaxoSmithKline Award at Membrane Proteins Conference today! Doryen's research into the membrane attack complex has opened new lines of investigation into the importance of lipids in immune homeostasis 0114
Phill Stansfeld @pstansfeld.bsky.social · 13/04/2026Thanks for visiting @figlegend.bsky.social. Safe travels back to Singapore. 020
Reposted by Phill Stansfelddavidroper2.bsky.social @davidroper2.bsky.social · 13/04/2026Last Friday Phill Stansfeld & I played host to Dr Shu Sin Chng from National University of Singapore on his latest research in Gram negative bacterial membrane biogenesis, a core aspect of joint interests relevant to discovery of next generation antibiotics and combating the rise of AMR 161
Reposted by Phill StansfeldMarc van der Kamp @marcvanderkamp.bsky.social · 20/03/2026Registration is open for the #CCPBioSim Annual Conference, 6-8 July, Bristol, UK! See: www.ccpbiosim.ac.uk/bristol2026 Delighted to be hosting the conference @bristoluni.bsky.social, with the theme "Biomolecular simulation across scales, for understanding and design" #compchem #compbio #biodesignccpbiosim.ac.ukCCPBioSim Annual Conference 167
Reposted by Phill StansfeldSéamus Holden 🔬🦠🧫 @seamusholden.bsky.social · 26/01/2026SAVE THE DATE! The next instalment of the long-running Bacterial and Archaeal Cell Division Conference will take place at www.marriott.com/en-us/hotels..., Italy from the 20th to 23rd of April 2027. Organisers: me, @s-lab.bsky.social, @awehenkel.bsky.social. More info soon. #MicroSkymarriott.com 03024
Phill Stansfeld @pstansfeld.bsky.social · 06/02/2026Should be a great meeting - Link here: www.eventsforce.net/biochemsoc/f...eventsforce.net 010
Reposted by Phill StansfeldLorraine Reese @lorraine-reese.bsky.social · 06/02/2026Internationally renowned as one of the leaders in neurotransmitter transport research, don't miss Professor Renae Ryan (@renaeryan.bsky.social) present her #BiochemSoc International Award Lecture at Membrane #Proteins Conference 2026! 🧪 095
Reposted by Phill StansfeldBiochemical Society @biochemsoc.bsky.social · 07/01/2026Save £100 if you book your place for Membrane Proteins Conference before 7 January 2026. Taking place on 7–9 April 2026 in Birmingham, don’t miss the chance to listen to expert researchers discussing membrane proteins in diverse biological processes. 🧪 ow.ly/rhHJ50XNBLI 046
Phill Stansfeld @pstansfeld.bsky.social · 25/12/2025🌟 New Tool Alert! We present MemPrO – a toolkit for orienting and building membrane protein systems: ✅ Membrane protein orientation ✅ Mixed membrane building ✅ Double membranes & curvature ✅ Peptidoglycan cell wall support 🔗 github.com/pstansfeld/mempro 📖 pubs.acs.org/doi/10.1021/...pubs.acs.orgMemPrO: A Predictive Tool for Membrane Protein OrientationMembrane proteins play a vital role in numerous cellular processes, including ion transport, intercellular communication, and antibiotic resistance. Ensuring their accurate orientation within lipid bi... 04913
Reposted by Phill StansfeldChris Mulligan @chrismulligan.bsky.social · 17/12/2025🚨My lab is hiring a postdoc!🚨 If you’re interested in working out the mechanism and physiological impact of bacterial lipid transport processes then please apply! Job advert is here: tinyurl.com/4swddfda Get in touch by email (c.mulligan@kent.ac.uk) for informal enquiries Please repost! Thanks! 1117
Reposted by Phill StansfeldVasileios Petrou @vasileiospetrou.bsky.social · 09/12/2025I'm happy to share that our work describing the #cryoEM #structure of the glycosyltransferase ArnC from Salmonella enterica has been published in Nature Communications. #membrane #protein #PetrouLab The article is open access and available at: www.nature.com/articles/s41...nature.comStructural basis of undecaprenyl phosphate glycosylation leading to polymyxin resistance in Gram-negative bacteria - Nature CommunicationsThe study reveals the structure of ArnC, a membrane glycosyltransferase that modifies undecaprenyl phosphate with aminoarabinose (L-Ara4N), leading to polymyxin resistance. The structure of ArnC in tw... 1257
Reposted by Phill StansfeldVasileios Petrou @vasileiospetrou.bsky.social · 09/12/2025Congratulations to the entire team, including lead author Khuram Ashraf and our excellent collaborators @pstansfeld.bsky.social (and team) and Jason Kaelber. The original preprint thread with additional information is here: bsky.app/profile/vasi... 031
Reposted by Phill StansfeldAllister Crow @allistercrow.bsky.social · 26/11/2025Type VII ABC transporters underpin many core activities in the bacterial cell envelope - including efflux, cell division and lipoprotein trafficking. A new paper in PLOS Biology reveals YbbAP-TesA as a novel Type VII system in E. coli. dx.plos.org/10.1371/jour...dx.plos.orgStructural characterization of the YbbAP-TesA ABC transporter identifies it as a lipid hydrolase complex that extracts hydrophobic compounds from the bacterial inner membraneIn E.coli, three of the four Type VII ABC transporter systems have been structurally characterized. This study solves cryo-EM structures of the fourth Type VII ABC system, YbbAP-TesA, and suggests tha... 02210
Phill Stansfeld @pstansfeld.bsky.social · 24/11/2025Super collaboration with @raffaeleieva.bsky.social and @fronzeslab.bsky.social on the LptDEMY complex. 0154
Reposted by Phill StansfeldRaffaele Ieva @raffaeleieva.bsky.social · 24/11/2025rdcu.be/eRxNf here our new study on the characterization of the lipopolysaccharide holotranslocon, LptDE and the newly identified subunits LptM and LptY. Great collaboration with @fronzeslab.bsky.social @pstansfeld.bsky.social @JulienMarcoux @YvesQuentinrdcu.beStructural basis of lipopolysaccharide assembly by the outer membrane translocon holo-complexNature Communications - The asymmetric distribution of lipopolysaccharide (LPS) on the surface of the bacterial outer membrane is essential and crucial for antibiotic resistance. Here, authors... 33115
Phill Stansfeld @pstansfeld.bsky.social · 12/11/2025Kat Blow has developed CCD2MD, a suite of packages for preparing co-folded outputs for MD simulations. Created for protein–lipid interactions in integral membrane proteins, it also works for peripheral and lipid-anchored proteins too. pubs.acs.org/doi/full/10.... github.com/keb721/ccd2mdpubs.acs.orgCCD2MD: A Suite of Packages for Preparing Co-Folded Outputs for Molecular Dynamics SimulationsProtein–lipid interactions play a crucial role in the stability and function of membrane proteins. While experimental approaches to characterize these interactions in a native-like membrane environmen... 0205
Phill Stansfeld @pstansfeld.bsky.social · 24/10/2025Biochemical Society's Membrane Protein Conference 7–9 April 2026 Birmingham, UK | Leonardo Royal Hotel - Abstracts welcome for talks & posters - Bursaries available! - Register & submit here: www.eventsforce.net/biochemsoc/f... #MembraneProteins #CallForAbstracts @biochemsoc.bsky.social 01011
Phill Stansfeld @pstansfeld.bsky.social · 04/10/2025Just in time for Becca’s thesis submission, their paper on MreB membrane interactions is published in @biophysj.bsky.social: www.cell.com/biophysj/ful... 🎉cell.comMreB filaments in the elongasome modulate E. coli membrane curvatureMreB, a bacterial actin homolog, plays a pivotal role in defining the shape of rod-shaped bacteria by coordinating peptidoglycan synthesis during cell elongation. It forms filaments that interact with... 0103
Phill Stansfeld @pstansfeld.bsky.social · 17/09/2025Fantastic WEHeraeus symposium at the Bad Honnef Physikzentrum, perfectly organised by @djanuliene.bsky.social and @arnemoeller.bsky.social. Thank you for the invitation. 0110
Phill Stansfeld @pstansfeld.bsky.social · 07/07/2025Józef Lewandowski and I have a JPIAMR-funded Postdoctoral position available. We are seeking a candidate to study antibiotic interactions with bacterial membranes using MD Simulations. The successful applicant will be part of a larger consortium of academic and industrial partners. bit.ly/3TVs74Owarwick-careers.tal.netResearch Fellow (110633-0625) - University of WarwickTitle: Research Fellow (110633-0625). Application Deadline: . Position Type: Fixed Term 044
Phill Stansfeld @pstansfeld.bsky.social · 07/07/2025Also a couple of back-to-back @natcomms.nature.com papers with @chelseabrown.bsky.social on Mycobacterial enzymes in collaboration with the Mancia lab et al.: doi.org/10.1038/s414... doi.org/10.1038/s414...doi.orgMechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE - Nature CommunicationsHere the authors investigate of the structural basis of substrate recognition and the catalytic mechanism of the mannosyltransferase PimE, which is crucial for the biosynthesis of phosphatidyl-myo-ino... 0154
Phill Stansfeld @pstansfeld.bsky.social · 07/07/2025New Paper with @deanelab.bsky.social: www.nature.com/articles/s41...nature.comConformational dynamics and membrane insertion mechanism of B4GALNT1 in ganglioside synthesis - Nature CommunicationsGangliosides are bioactive lipids important for neuronal cell function. Here, authors reveal the dynamic structure of the ganglioside synthetic enzyme B4GALNT1 and demonstrate how it inserts into memb... 060
Phill Stansfeld @pstansfeld.bsky.social · 07/07/2025New paper out, with a contribution from Dom Gurvic and I; led by Andy Lovering and @lalouxlab.bsky.social: www.nature.com/articles/s41...nature.comA porin-like protein used by bacterial predators defines a wider lipid-trapping superfamilyNature Communications - This study reveals that an outer membrane protein from the predator Bdellovibrio bacteriovorus forms a pentameric assembly that traps a lipid monolayer within. This allows... 0337
Reposted by Phill StansfeldRobin Corey @robincorey.bsky.social · 27/03/2025Check out our new paper with Michael Landreh, @pstansfeld.bsky.social and others in @elife.bsky.social : Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization doi.org/10.7554/eLif...doi.orgEngineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization 0145
Reposted by Phill StansfeldMelissa Webby @melissawebby.bsky.social · 11/12/2024You or someone you know interested in cell envelopes and getting a PhD? Come join me warwick.ac.uk/fac/cross_fa... or have a look at some of the other fantastic projects on offer @uni-of-warwick.bsky.socialwarwick.ac.ukDr Melissa WebbyDr Melissa Webby 0510
Reposted by Phill StansfeldMartin Vögele @martinvoegele.bsky.social · 29/11/2023An interesting tool that employs MD Simulations to explain lipid densities in cryo-EM maps. www.nature.com/articles/s41...nature.comLipIDens: simulation assisted interpretation of lipid densities in cryo-EM structures of membrane pr...Interpretation of lipid-like densities in cryo-EM structures of membrane proteins is challenging. Here authors present LipIDens, enabling molecular dynamics analysis of protein-lipid interactions. 081
Phill Stansfeld @pstansfeld.bsky.social · 13/10/2023🚨Job Alert🚨 As part of our BBSRC sLoLa award, David Roper, @seamusholden.bsky.social and I have three 5-year PDRA positions available. Each is individually tailored to our groups, but will be part of the larger interdisciplinary team; also including Stephen Cochrane's group at QUB: t.co/alJ0re8BBht.co3 x Research Fellow positions available to work on collaborative project - Coventry3 x Research Fellow positions available to work on collaborative project between the Roper, Holden & Stansfeld laboratories at the School of Life S... 22223