Reposted by Institut Pasteur | 130 years of biomedical research
Our paper outlining a deep learning-based phenotypic screening method to discover new TB drugs is out in @science.org #ScienceAdvances 💊🦠
It's the result of a great collaboration between the labs of @chzimmer.bsky.social and @awehenkel.bsky.social at @pasteur.fr!
📃 www.science.org/doi/10.1126/...
science.org
Deep learning extracts MoA-specific signatures from high-throughput images of chemically and genetically perturbed Corynebacteria
To address drug-resistant tuberculosis, the leading single-pathogen infectious killer, drugs with novel modes of action (MoAs) are urgently needed. Phenotypic screening of chemical libraries can ident...