Viruses are ubiquitous mobile genetic elements that are obligate symbionts of cellular life forms and replicate exclusively within host cells. The ...

Illumina and Oxford Nanopore as main contenders in this field

Scientists have found smallpox viruses in the remains of people in Chile from around 500 years ago, revealing how the virus may have evolved into a global killer.

Aguirre et al. describe a model of gene regulatory networks and show how their properties shape the distribution of genetic effects on gene expression. Their results imply constraints on real network ...

Nature Human Behaviour - Polygenic risk scores are not genetic predispositions

Limited access to medical professionals and irresponsible prescribing practices are contributing to antimicrobial resistance in low-resource settings.

This Review discusses how long noncoding RNAs (lncRNAs) control transcription activation by RNA polymerase II, including how they are produced at active enhancers or chromatin-domain boundaries and ac...

Healthy coral reefs have an acoustic signature known to be attractive to coral and fish larvae during settlement. Here the authors use playback experiments in the field to show that healthy reef sound...

A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields

Travelling wave delay of the basilar membrane in age-related hearing loss

Abstract. Interphase chromosomes are mainly shaped by loop extrusion and compartmentalisation mechanisms. However, their temporal component and cause-effec

In 1926, in response to urban sprawl and increasing motor car traffic, a group met at Oriel College to ‘to form a Society for the preservation of Footpaths, Bridlepaths and Commons in the neighbourhoo...

INSTALL overcomes fundamental challenges for DNA delivery and integration methods by synergizing immune-stealth nucleic acids with recombinases to enable kilobase-scale integration strategies without ...

The Institute of Human Genetics invites applications for a Principal Investigator position in its main research areas. Read more...

A tissue-engineered esophageal segment is functional in minipigs.

ANTIBIOTIC prescriptions in Australia have increased, antibiotic resistance is on the up, and less than half the antibiotics given after surgeries were appropriate, according to the Australian Centre ...

In this Review, Castañeda-Barba, Top and Stalder use the One Health framework to synthesize the recent literature on the ecological and evolutionary factors that determine the successful local and glo...

Antimicrobial resistance threatens our health and economic security. Organizations are urged to sign the Davos Compact on AMR to tackle this global threat.

YouTube video by John Greally

Microflora Danica—an atlas of Danish environmental microbiomes—reveals that although human-disturbed habitats have high alpha diversity, species reoccur, revealing hidden homogeneity.

From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...

The inquiry says an earlier lockdown could have saved 23,000 lives in the first wave in England - and lockdown could have been avoided altogether with earlier interventions.

Early loss of small extraislet β cells in children with type 1 diabetes could explain age-related differences in disease.

Differences in a specific region of the Neanderthal genetic code may have contributed to their distinctive protruding jawline, a study suggests.

Biotech, Next Generation Sequencing, Single cell and Spatial Biology, Next Generation Proteomics, Synthetic Biology, Small Molecules and Biologics pharma, and related topics. Click to read Rhymes with...

Decisions about critical care are almost always made without access to genetic information. The authors report the application of a new method of DNA sequencing in infants in a neonatal intensive c...

Reassessing Discovery: Rosalind Franklin, Scientific Visualization, and the Structure of DNA - Volume 79 Issue 1

In primed human pluripotent stem cells (hPSCs) resembling post-implantation epiblast, numerous lineage-specific enhancers assume the poised chromatin state, co-marked by H3K4me1 and Polycomb-associate...

My vision was based on sharing, not exploitation – and here’s why it’s still worth fighting for

The cerebellum is implicated in nearly every domain of human cognition, yet our understanding of how this subcortical structure contributes to cognition remains elusive. Efforts on this front have ten...

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