Reposted by Fernando RossineSternberg Lab @sternberglab.bsky.social · 12/05/20261/9 New preprint from the Sternberg Lab in collaboration with the Nishimasu Lab! We uncover how the DRT3 antiphage immune system pairs two reverse transcriptases, one RNA-templated and one protein-templated, to build a double-stranded DNA effector. doi.org/10.64898/202... 27028
Reposted by Fernando RossineTami Lieberman @contaminatedsci.bsky.social · 06/05/2026Dr. Indra Gonzalez Ojeda gave a great thesis defense this morning, including some wisdom for starting PhD students, or frankly, anyone. 26017
Fernando Rossine @fernpizza.bsky.social · 27/11/2025This Plasmid Project was directly inspired by the results on multilevel selection that Dan introduced me to! In this thread he explains some fundamental theoretical results that were so influential to me as a Scientist. Looking forward to more Math-driven experiments!!! Thanks Dan! 041
Reposted by Fernando RossineLiana Merk @bacteriyay.bsky.social · 20/11/2025This is it!!! This is the work I never want to stop hearing about. Kepler’s creativity and curiosity really shine through in this paper. Give it a read and enjoy 😎 1103
Fernando Rossine @fernpizza.bsky.social · 21/11/2025This has been an intense, crazy week. My plasmid competition paper is finally out and we have a new preprint on Bioarxiv! Plus I'm leaving the US after 10 years here. See you soon America! Hello Zurich!!! 3393
Fernando Rossine @fernpizza.bsky.social · 21/11/2025When different kinds of mobile genetic elements get together, they become even more powerful catalysts for microbial evolution! In this work we discovered a mechanism by which Insertion Sequences drive their spread across Plasmids, which helps explain this evolutionary potential! 132
Fernando Rossine @fernpizza.bsky.social · 21/02/2025I'm so happy that I can finally share the results of my first postdoc paper with @baym.lol!!! Turns out plasmids are an amazing system to study multi-scale evolution and we can track within-cell and between-cell dynamics! (1/n) www.biorxiv.org/content/earl...biorxiv.orgIntracellular competition shapes plasmid population dynamicsConflicts between levels of biological organization are central to evolution, from populations of multicellular organisms to selfish genetic elements in microbes. Plasmids are extrachromosomal, self-r... 1019784