Ribosome hibernation helps cells survive stress by reversibly silencing translation and preserving ribosomal complexes. Although well characterized in bacteria and eukaryotes, archaeal hibernation rem...

Bacteriophages (phages), viruses that parasitize bacteria, hold tremendous potential as antimicrobial agents, microbiome modulators, and industrial biocontrol tools; yet clinical and environmental app...

Communications Biology - Two coinfecting archaeal viruses provide insights into virus-virus interactions

Transposable elements mobilize within and occasionally between genomes, including from host to virus. We identified two insertions of the human BC200 noncoding RNA gene in the poxvirus molluscum conta...

Viruses are ubiquitous mobile genetic elements that are obligate symbionts of cellular life forms and replicate exclusively within host cells. The ...

CRISPR-Cas provides RNA-mediated adaptive immunity, but how its first RNA-guided effector arose is unclear. In this study, we report the discovery of Viral Interference Programmable Repeat (VIPR) syst...

Taillefer et al. show that a bacterial type VI secretion system is lost or attenuated during experimental evolution when it provides no competitive advantage but is maintained in the presence of susce...

Viruses are ubiquitous mobile genetic elements that are obligate symbionts of cellular life forms and replicate exclusively within host cells. The ...

Many prokaryotes are diderms. They divide using an FtsZ division ring to simultaneously constrict physically coupled inner and outer membranes to form daughter cells with two membranes. Currently, onl...

Author summary Bacteriophages are among the most abundant biological entities in the oceans. While most known phages use a tail to recognize and infect bacteria, simpler non-tailed phages may be just ...

Recent discoveries on bacterial immunity have revealed that several protein domains involved in anti-phage defense are conserved in eukaryotes, such as SIRim, TIR, PNP and gasdermin. Bacterial immune ...

During replisome assembly of monkeypox virus, the hexameric helicase–primase E5 undergoes large-scale conformational changes that allow two of its primase domains to interact with the polymerase F8 th...

Bacterial ribosomes can synthesize proteins encoded within their own RNA.

The Secor Lab seeks a postdoctoral researcher to investigate bacteriophage biology in the Lyme disease spirochete Borrelia burgdorferi. The successful candidate will help define how phiBB-1 controls h...

Animal cells extensively remodel their cytoskeleton during differentiation and can notably switch between two major motility modes: flagellum-based swimming and actin-based crawling. We previously sho...

In this Review, Abergel et al. overview infection cycles across the Nucleocytoviricota phylum, highlighting shared mechanisms and lineage-specific features spanning viral entry, viral factory formation, genome replication, virion morphogenesis and egress, and discuss key unresolved questions in the field.

Abstract. A virus with a circular single-stranded DNA genome, HthCRESSV1, was discovered in an oomycete, Halophytophthora thermoambigua, isolated from brac

A genomic screen reveals homologues of ESCRT components in mirusviruses that infect unicellular aquatic eukaryotes.

Biol Chem · 26 Aug 2026 — A long-lasting dogma regarding the membranes of prokaryotes is the distinct lipid composition of archaea and bacteria. Bacterial phospholipids consist of acyl chains that are...

The International Committee on Taxonomy of Viruses (ICTV) is considering a proposal submitted in July 2025 to create an optional additional taxonomic rank below the level of species. This was designed...

A genomic screen reveals homologues of ESCRT components in mirusviruses that infect unicellular aquatic eukaryotes.

Nature Microbiology, Published online: 26 August 2026; doi:10.1038/s41564-026-02470-9A genomic screen reveals homologues of ESCRT components in mirusviruses that infect unicellular aquatic eukaryotes.

Dibsy et al. show that proteasomal degradation of the Aurora B kinase is required for cytokinetic abscission in human cells. Aurora B degradation reduces the phosphorylation of its substrate, CHMP4C, ...

Inside cells, DNA is intimately associated with proteins, forming chromatin. The protein constituents of chromatin vary across the tree of life: histones are the principal building blocks of chromatin...

Background Asgard archaea, broadly considered as a group of archaea that exhibit the closest evolutionary relationship with eukaryotes, encode diverse defense systems and are infected by distinct viru...

Author summary Bacteriophages, or phages, are viruses that infect bacteria and play central roles in shaping microbial communities across ecosystems. Despite their ecological importance, the bacterial...

Archaea and bacteria routinely live side by side in microbial communities and must interact at least on occasion. Whether such cross-Domain interactions are dominated by mutual disregard, co-operation...