iiinova — where your digital self keeps evolving

Biosciences Area at Berkeley Lab @biosci.lbl.gov · 26/09/2026

Congratulations to Hakyung Lee of #BioBSE and the Advanced BioProcess Development Unit (ABPDU)! 🎉 We look forward to your Bay Area Regional Slam debut in October!

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 24/09/2026

Jack here! I recently met with Kateryna Zhalnina of #BioEGSB to get an overview of a new EcoPOD-centered project and how they're being used reduce ♻️ nitrogen pollution. EcoPODs are fabricated ecosystems designed for large plants, allowing researchers to better mimic how plants exist in the field 🌾.

A person with long brown hair and wearing a lab coat poses in front of two EcoPODs.

A group of researchers in lab coats pose in front of an EcoPOD, with a sorghum plant ready to be loaded behind them.

EcoPOD growth chamber with potted plants, overhead camera/sensors, in-soil sensors and connected control hardware.

Lab air-handling unit: stacked beige HEPA filter boxes with ducts and a computer showing a green-screen interface.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 23/09/2026

Today at 3 p.m.: Cheer on Hakyung, Flavien, and Sora as they take the stage for the 2026 Berkeley Lab Research SLAM. Watch in person in the Building 50 Auditorium (only IRL attendees are eligible to cast votes for the "Audience Choice" winner) or virtually at streaming.lbl.gov. #LabSLAM2026 #NPAW

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 21/09/2026

#BioBSE scientist @jaykeasling.bsky.social received the @uofcalifornia.bsky.social Regents Innovation Award for Distinguished Lifetime achievement. Jay, CEO of the @jbei.lbl.gov, received the award for a career of sustained innovation and visionary research in synthetic biology. 🙌

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 18/09/2026

Our final 2026 Berkeley Lab Research SLAM contender, Sora Yu, is a postdoc in the #BioEGSB Division studying microbiomes and metabolic engineering. She will present her talk, "Can't Move Out? Remodel the Neighbors!" to a panel of esteemed judges and vie for a top-three spot. Go, Sora! 🤩🎉

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 17/09/2026

Our next Berkeley Lab Research SLAM finalist, Flavien Maucourt, is a postdoctoral researcher in the #BioEGSB Division. On Sept 23, he'll give us the outlook for phage therapy as an antibiotic alternative, in just 3 minutes! Bonne chance, Flavien!

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 15/09/2026

The 9th annual Berkeley Lab Research SLAM is September 23. We're pleased to introduce our Biosciences 2026 contenders. First up is Hakyung Lee, a postdoctoral researcher in the #BioBSE Division who will present her research on a "picky, metal-shopping bacterium." We're rooting for you, Hakyung! 🤩🎉

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Reposted by Biosciences Area at Berkeley Lab

Joint Genome Institute @jgi.doe.gov · 02/09/2026

A Lake Mendota time series found invasive zooplankton prompted giant viruses to increase replication rates while maintaining protective DNA mechanisms—suggesting viral-like capability + bacterial-like stability More: jgi.doe.gov/user-science/science-st…

Digital mockup of a giant virus from JGI Genome Portal (credit: Ella Maru Studio)

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 03/09/2026

After 30 years, the @als.lbl.gov, a DOE Office of Science user facility located at Berkeley Lab, has reached its performance limits. Upgrades to harness brighter, more coherent light are in progress and will enable new research breakthroughs—in fields from physics to biology—for decades to come.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 02/09/2026

Jack here! I recently went to see the Multimodal Optical Scope with Adaptive Imaging Correction (MOSAIC) instrument in person. MOSAIC is a powerful new microscope 🔬 that combines 10+ imaging techniques into a single machine, allowing users to swiftly switch between modes without disrupting a sample.

Members of the lab where MOSAIC was developed pose for a group photo.

MOSAIC interior with motors, mirrors, lenses and cables that redirect light into new paths when modes change.

3D control software screenshot of MOSAIC: optical system with colored light paths and labeled components.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 31/08/2026

Congrats to #BioBSE researchers Aindrila Mukhopadhyay and co-PI Aparajitha Srinivasan on their funded FY27 FICUS Research proposal! The will study dynamic stress adaptation in a microbe, which could boost #biomanufacturing. www.emsl.pnnl.gov/news/ten-pro... @berkeleylab.lbl.gov @jgi.doe.gov

emsl.pnnl.gov

Ten Proposals Selected for Fiscal Year 2027 FICUS Research Call

Projects were designed to address high-risk, high-payoff activities within three topic areas

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 25/08/2026

Jack here! I visited #BioMBIB researcher Aris Polyzos to learn about his team's latest work, which identified an overlooked aspect of Huntington's disease. They were able to draw a link to Huntington's neurodegeneration by looking at DNA breakage; they were then able to reverse it in mice.

Two people smile at the camera, the one on the left is wearing safety glasses. Between them a large imaging tool is on, displaying large clumps of neurons in software.

A large machine called a cryotome, used for thinly slicing frozen samples.

A person in a lab coat is standing at a microscope with a digital display, the display is showing macrophages.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 24/08/2026

Congratulations to #BioMBIB faculty scientist @jenniferdoudna.bsky.social on being named a 2026 American Chemical Society @acs.org fellow! 🎉

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 21/08/2026

Researchers at Berkeley Lab and collaborating institutions developed a reconfigurable microscope that consolidates more than ten imaging techniques into one instrument. It processes its massive datasets using nersc.bsky.social + computational tools developed by #BioMBIB's Gokul Upadhyayula.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 19/08/2026

Jack Here! I met with #BioEGSB researcher Laura Cook to learn about her team's work to uncover the underlying mechanisms behind how faces 🐔 🐭 are structured. Laura's team is focused on studying enhancers—regions of genetic information that control when, where, and how much of a gene is expressed.🧬

Two people in lab coats look towards a computer monitor, the person on the left is pointing at the screen.

Two researchers face the camera with a computer monitor in the background.

A researcher wearing a protective gown and hair net looks into a microscope.

A collage of many bird and rodent faces, the birds are in the top grids and the rodents in the bottom.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 17/08/2026

Berkeley Lab #BioMBIB researchers in collab with @hsph.harvard.edu colleagues revealed an overlooked characteristic of Huntington's disease and demonstrated in mice that treatment with an antioxidant suppressed the neurodegenerative damage and symptoms of the disease. Read more via link in comments.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 13/08/2026

Jack here! To learn how researchers are upcycling ♻️ the industrial paper byproduct lignin, I visited Ning Sun at the Advanced BioProcess Development Unit (ABPDU). Lignin is a major waste 🔥 product from paper; Ning's team developed a method to convert it into useful chemicals (benzylamines). ✨

Two people in lab coats stand, smiling to the camera, in front of a large vat with many pipes attached.

A large industrial mixer used in a lab setting for mixing, stirring, homogenizing and dispersing compounds.

$A fractional distillation setup with many glass flasks attached.$

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 11/08/2026

"[Sorghum is] grown in some of the most challenging environments in the world, which I think is pretty interesting, often where heat, drought, poor soils, and limited inputs are real constraints." Nadia Shakoor, @danforthcenter.bsky.social #genomics @jgi.doe.gov @berkeleylab.lbl.gov

bsky.app

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 10/08/2026

When people ingest shellfish harvested from waters affected by a red tide, the harmful saxitoxin can lead to paralytic shellfish poisoning. No antidote exists, but researchers recently confirmed a naturally occurring protein in frogs can reverse the lethal effects of red tide toxin in mice. Link 👇.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 07/08/2026

Faces are one of the most diverse anatomical features, but how can the facial structure of birds and mammals vary so drastically when we share the majority of our DNA? Work from #BioEGSB researchers Laura Cook and @axelvisel.bsky.social uncovers what may be the driving force of facial morphology.

A collage highlighting the differences in faces between birds and mammals, the top column contains 5 birds, the bottom column contains 5 rodents.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 06/08/2026

Can we hack photosynthesis to fight climate change? 🌱 A review co-authored by #BioMBIB's Kris Niyogi maps out how genome-edited crops could become a cornerstone of global carbon management through enhanced carbon sequestration! Read more: www.nature.com/articles/s44...

nature.com

Genome engineering of plant photosynthesis for carbon sequestration - Nature Reviews Bioengineering

Gene editing to enhance photosynthesis in crop plants offers a strategy to boost plant carbon capture and mitigate climate change. This Review explores the agronomic, molecular and technical challenge...

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 04/08/2026

A hidden treasure lies within lignin—every year 100 million tons of lignin is produced, yet most of it is wasted. Researchers at @berkeleylab.lbl.gov developed a scalable method for turning lignin into benzylamines, chemicals used in the production of dye, fertilizer, pesticide, and pharmaceuticals

Two researchers in lab coats and safety glasses hold a beaker of dark liquid and a dish of brown powder in a lab.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 03/08/2026

We are excited to see so many familiar faces among the recipients of the @jgi.doe.gov - @molecularfoundry.lbl.gov Critical Minerals & Materials call. We are looking forward to writing about all of your great discoveries! @berkeleylab.lbl.gov

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 31/07/2026

Jack here! I toured the SIBYLS Beamline at the @als.lbl.gov with #BioMBIB researcher Scott Classen. Scott is working on BilboMD, a computational platform for predicting protein structures based off real world X-ray data. The website is free, making it super easy for other researchers to use.✨

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 30/07/2026

Today is #NationalInternDay, and we are thrilled to spotlight Jack Addison, a SULI intern who has worked with our communications team this summer. Jack has been the creative force behind our first-person social media content. Thank you for helping us share the story of Biosciences Area research!

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 29/07/2026

Today we wrap up our retiree celebration by wishing Bill Jagust all the best as he embarks on a new chapter after 39 years on #TeamBioSci. He redefined the PET brain imaging program using new tracers to study aging and dementia and will continue as a professor at UC Berkeley. Congratulations, Bill!

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 28/07/2026

Berkeley Lab researchers combined experimental data with AI and supercomputers to develop a new web-based platform that accelerates structural insights. Learn about how they're bringing a new angle to studying proteins: biosciences.lbl.gov/2026/07/27/a-ne…

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 27/07/2026

Continuing our retiree celebration, today we acknowledge Olga Diaz's 21+ years with Berkeley Lab—18 of them as executive assistant to @jbei.lbl.gov CEO Jay Keasling @keaslinglab.bsky.social . Thanks for supporting science on #TeamBioSci, Olga!

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 23/07/2026

Congratulations to Eltra Green on her impending retirement at the end of the year. As business manager for the Biosciences at Berkeley Operations Center, Eltra has kept us "in the pink"—her favorite color 🩷. #TeamBioSci wishes you all the best! 🎉

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 22/07/2026

Today we're kicking off a celebration of our 2026 retirees by acknowledging Wendi Lynch's 10 years of service as a senior administrator for the @jgi.doe.gov. Thank you for supporting science on #TeamBioSci, Wendi. Enjoy your next adventure!

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 21/07/2026

Hi, Jack here! I recently met #BioEGSB’s Peter Andeer for a tour of the EcoBOT self-driving lab. The latest in a line of evolving plant–microbe 🌱🦠 research tech developed at Berkeley Lab, EcoBOT autonomously manages small ecosystems, EcoFABs, that control growth conditions to the microbial level 🧫.

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Reposted by Biosciences Area at Berkeley Lab

Joint Genome Institute @jgi.doe.gov · 13/07/2026

Straight from the headlines! Learn more about the July cover story from @natmicrobiol.nature.com on the latest episode of our #GenomeInsider podcast — "The Mobilome in the Mire" 🦠 Find it here: jgi.doe.gov/user-science... @simrouxvirus.bsky.social @scbagby.bsky.social @biosci.lbl.gov

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 13/07/2026

A recent article about fungal dye production included work by @jbei.lbl.gov & #BioBSE scientist Aindrila Mukhopadhyay. Making synthetic indigo is a toxic process. Aindrila’s team engineered genes into the fungus Rhodosporidium Toruloides to naturally produce the similar indigoidine dye. Read more 👇.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 07/07/2026

Built by a team of Berkeley Lab biologists, mathematicians, and engineers, EcoBOT is a self-driving lab that uses advanced computer vision to track plant growth with unprecedented precision. It then applies algorithms to analyze that data and autonomously design and perform follow-up experiments.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 02/07/2026

Hi all, Jack here! I recently toured Theia, the powerful custom cryo-EM project led by #BioMBIB scientist Holger Müller. Typical cryo-EMs sacrifice resolution for contrast; Theia uses a laser phase plate to increase contrast while maintaining a higher resolution thanks to its custom configuration.

Two people wearing protective glasses stand next to each other, smiling in front of a tall, complex lab instrument, a cryogenic electron microscope, with many cables and large metal parts.

Cryogenic electron microscope interior with the tall microscope column, liquid nitrogen chamber, and numerous bundled cables and control modules. Text boxes on the image say, "Cryo-EMs start with an electron beam that passes through the specimen and into an objective lens. Theia uniquely has an abberation corrector and the laser phase plate." and "The liquid nitrogen freezes samples to about -190°C"

A researcher points towards an array of mirrors inside a cryogenic electron microscope cabinet while looking towards someone asking a question. The array surrounds the microscope body, cables and control modules are present in the background.

Lab laser optics with steel chamber holding a phase plate. In the background are cables, and an array of mirrors ends into an attached smaller chamber. Text boxes on the image say, "Here is where the laser enters to be focused by a pair of mirrors, building up the intensity to be the brightest continuous laser focus ever." And, "This chamber contains the laser phase plate."

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 29/06/2026

Hi everyone, my name is Jack. I'm a SULI summer intern at Berkeley Lab. Over the next several weeks I’ll be creating posts sharing my experiences learning about cool research projects across the Biosciences Area. I hope you enjoy this series as I much as I enjoy making it!

Person with dark shoulder-length hair wearing a dark long-sleeve t-shirt and jeans stands near some large rocks in front of the facade of a building with a large number 92.

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Joint Genome Institute @jgi.doe.gov · 25/06/2026

One more reason to watch the World Cup ⚽: In 2022, JGI User @szintri.bsky.social and his team looked at grasses for clues about crop resilience — and spotted their study species on stadium pitches! Hear their story: jointgeno.me/s04e01

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 22/06/2026

Theia is a custom cryo-EM that uses a laser-based phase-contrast plate to produce high-res images. #BioMBIB's Holger Müller led R&D in collab w/ @berkeleylab.lbl.gov & @ucberkeleyofficial.bsky.social physicists and machinists with support from @biohub.org.

f.mtr.cool

Enjoy the videos and music that you love, upload original content and share it all with friends, family and the world on YouTube.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 19/06/2026

Congratulations to @jbei.lbl.gov's Corinne Scown on being named one of the 2026 Top Agri-food Pioneers by the World Food Prize Foundation! Scown's work focuses on modeling the economic and environmental impacts of advanced pathways to bio-based fuels and products. Link to read more in comments. 👇

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 18/06/2026

Structural biology + AI-assisted computer modeling + Directed evolution = A faster path to protein design. By manipulating the “promiscuity” of a designed protein, a team including #BioMBIB faculty scientist James Fraser created two novel proteins with specialized functions. Link in comments. 👇

Colorful graphic with a photo of a researcher and a quote about how observing promiscuous protein binding enabled the creation of an enzyme 10x more active than previous designs.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 12/06/2026

Leveraging new tools and large-scale data mining, @jgi.doe.gov researchers nearly tripled the available fungal mitochondrial genome data, unlocking new potential for AI-driven studies of energy metabolism. 🍄 Read the full story: lnkd.in/guExxUg5

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 11/06/2026

Phage Foundry lead @vivekmutalik.bsky.social was mentioned in a Q&A by Aeron Hammack of the @molecularfoundry.lbl.gov. Phages are bacterial antagonists useful in medicine; Phage Foundry is making a database of them. Mutalik’s team saves researchers resources by bypassing a demanding research phase.

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Innovative Genomics Institute @innovativegenomics.bsky.social · 08/06/2026

Out today in Nature, new research from Jennifer Doudna, postdoc @jingkunzeng.bsky.social, and collaborators shows a #CRISPR-based method for selectively killing "undruggable" #cancers by recognizing cells with cancer-causing mutations and shredding their DNA. Learn more: ow.ly/NRss50Z8tQK

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 05/06/2026

Quantum tech is growing, but the industry faces a critical shortage of trained scientists and engineers. Berkeley Lab’s A-LIFT Office and Sandia National Laboratories are bridging this gap through the QCaMP program! Read more about our impact and how to get involved: go.lbl.gov/QCaMP

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 03/06/2026

Nuclear medicine got it's start in what would become the Biosciences Area at @berkeleylab.lbl.gov. The field is now undergoing a massive evolution. Hear about the shift from traditional beta-emitting isotopes to the high-energy power of alpha emitters. 🎧 youtu.be/xHwxfi71RCE

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 28/05/2026

How can quantum-related phenomena exist in the "warm, wet, and noisy" environments of living systems? A new @pnas.org perspective from @princeton.edu's Gregory Scholes and #BioMBIB’s Graham Fleming lays out where the field of quantum biology stands — and where it's going next.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 27/05/2026

At Berkeley Lab, we share our main campus with a plethora of critters—snakes, turkeys, deer, and bobcats, to name a few. But we don't have baby bison like @fermilab.bsky.social does! Enjoy a few pics courtesy of our fellow national lab colleagues for #WildlifeWednesday.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 20/05/2026

@ucsanfrancisco.bsky.social researchers led by #BioMBIB faculty scientist @fraserlab.com pioneered a new method to guide rapid design of super-powered proteins. They leveraged nat'l lab light sources including the @als.lbl.gov's beamline 8.3.1 run by fellow MBIB faculty scientist James Holton.

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 12/05/2026

Gary Karpen, a senior faculty scientist in #BioBSE and @berkeleymcb.bsky.social professor, is among the 2026 class elected to the @nasonline.org. Karpen studies how the structure, organization, and maintenance of genetic material impact inheritance and cell function. go.lbl.gov/Karpen-NAS

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Biosciences Area at Berkeley Lab @biosci.lbl.gov · 07/05/2026

Stop by the @berkeleylab.lbl.gov booth at #SynBioBeta2026 and learn how to work with the Agile BioFoundry and @jgi.doe.gov to access our resources!

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