Researchers have used advanced X-ray crystallography methods to determine the structure of an archaeal protein at unprecedented resolution

Registration for the 2026 CCP4 Northern Structural Biology Meeting is now open! Join us at Newcastle University from Wednesday 11 to Friday 13 November 2026 (now expanded to three days up from two last year). We’re expecting around 100 delegates from universities across the North of England and beyond, with talks from PhD students and …

CCP4 Northern meeting 2026 keynote speaker announced: Prof. Laura Spagnolo (Glasgow) will speak 11–13 Nov in Newcastle.

This EMBO Workshop on Marine Microbial Chemical Communication will bring together researchers at the forefront of understanding the chemical crosstalk of microbial interactions in the ocean. As micr…

Nature Microbiology, Published online: 30 June 2026; doi:10.1038/s41564-026-02412-5Screening 1,572 compounds for mycomembrane permeation plus cheminformatic and machine learning analyses reveals features associated with improved permeation in the pathogen Mycobacterium tuberculosis and model organism M. smegmatis.

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Structural analysis of endogenously expressed proteins in Mycobacterium smegmatis reveals an asymmetric short-chain/long-chain hybrid acyl‑CoA carboxylase that comprises 16 subunits with (AccA3)4–AccE...

Covering: This review covers literature from 2015 to present.It is widely recognised that there is a significant gap between bacterial natural product potential and detected/described products. As suc...

β-mannans are plant structural and storage polysaccharides prevalent in the human diet. Their degradation in the gastrointestinal tract is mediated by the human gut microbiota (HGM) through expression...

Structures of the heterodimeric ATP-binding cassette (ABC) transporter TM287/288 have previously been determined in several states indicating large conformational changes during its reaction cycle. Ho...

Iron is an essential element that can be growth-limiting in microbial communities, particularly those present within host organisms. To acquire iro...

PhD Project - Resolving the mechanism of Mycobacterium tuberculosis antibiotic tolerance through single-molecule microscopy at Newcastle University, listed on FindAPhD.com

PhD Project - Molecular mechanisms of siderophore-mediated iron uptake in Fungi at Newcastle University, listed on FindAPhD.com

PhD Project - Hiding in plain sight: How a multi-drug resistant pathogen evades detection and killing by human neutrophils at Newcastle University, listed on FindAPhD.com

Thousands across the UK set to benefit from re-opening of the historic Erasmus+ programme

Research Fellow - AR3262, School of Biology Salary: Grade 6 / £38,784 pa Start date: 1 July 2026 Full time Fixed term: 36 months, <p><span>Applications are sought for a committed Post-doctoral Research Fellow to work with Dr Rafael Guimaraes da Silva conducting research for a Leverhulme Trust Research Grant funded project to dissect catalysis and allostery in a gut microbiome ATP phosphoribosyltransferase enzyme.&nbsp; The primary duties will be to uncover the catalytic and allosteric mechanisms via protein crystallography and enzymology.</span></p> <p><span>The successful applicant will have (or be near to completion of) a PhD in Biochemistry or Structural Biology with expertise in X-ray crystallography and enzymology.&nbsp;</span></p> <p><span>The post is available for 36 months starting 1^st July 2026 or as soon as possible thereafter. </span></p> <p><span>Further information and informal enquiries may be directed to Dr Rafael Guimaraes da Silva at&nbsp;</span>rgds@st-andrews.ac.uk</p> <p>&nbsp;</p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;"><strong>Benefits:</strong></p> <ul style="margin-top: 0px; margin-bottom: 1rem; padding-left: 2rem;"> <li style="margin: 0cm 0cm 4pt; text-align: justify; line-height: normal;"><span style="line-height: normal;">&nbsp; &nbsp; &nbsp; &nbsp;</span><span>Financial contribution to&nbsp;</span><a href="https://www.st-andrews.ac.uk/hr/payandpensions/removalandrelocationpolicy/" style="color: #565661; background-color: transparent;">relocation</a>&nbsp;<span>(subject to eligibility)</span></li> </ul> <ul style="margin-top: 0px; margin-bottom: 1rem; padding-left: 2rem;"> <li style="margin: 0cm 0cm 4pt; text-align: justify; line-height: normal;"><span style="line-height: normal;">&nbsp; &nbsp; &nbsp; &nbsp;</span><span>Membership of the USS Pension Scheme with generous employer contributions of 14.5%</span></li> </ul> <ul style="margin-top: 0px; margin-bottom: 1rem; padding-left: 2rem;"> <li style="margin: 0cm 0cm 4pt; text-align: justify; line-height: normal;"><span style="line-height: normal;">&nbsp; &nbsp; &nbsp; &nbsp;</span><span>A hybrid working environment, including partial homeworking where appropriate and a range of family friendly policies, supporting work-life balance</span></li> </ul> <ul style="margin-top: 0px; margin-bottom: 1rem; padding-left: 2rem;"> <li style="margin: 0cm 0cm 4pt; text-align: justify; line-height: normal;"><span style="line-height: normal;">&nbsp; &nbsp; &nbsp; &nbsp;</span><span>Staff discount scheme for local and national goods and services</span></li> </ul> <ul style="margin-top: 0px; margin-bottom: 1rem; padding-left: 2rem;"> <li style="margin: 0cm 0cm 4pt; text-align: justify; line-height: normal;"><span style="line-height: normal;">&nbsp; &nbsp; &nbsp; &nbsp;</span><span>Free staff parking, employee Carshare and Cycle to Work Schemes and subsidised local bus travel</span></li> </ul> <ul style="margin-top: 0px; margin-bottom: 1rem; padding-left: 2rem;"> <li style="margin: 0cm 0cm 4pt; text-align: justify; line-height: normal;"><span style="line-height: normal;">&nbsp; &nbsp; &nbsp; &nbsp;</span><span>Subsidised sports membership, reduced tuition fees on degree programmes for staff, access to training and development opportunities including LinkedIn Learning, access to library facilities, salary sacrifice scheme</span></li> </ul> <ul style="margin-top: 0px; margin-bottom: 1rem; padding-left: 2rem;"> <li style="margin: 0cm 0cm 4pt; text-align: justify; line-height: normal;"><span style="line-height: normal;">&nbsp; &nbsp; &nbsp; &nbsp;</span><span>34 Days Annual Leave plus 5 Public Holidays.</span></li> </ul> <p><span><br> </span></p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;"><em>At St Andrews, equality, diversity, and inclusion are central to who we are and form a core pillar of our University Strategy. We are committed to creating a fair, inclusive and supportive workplace, reflected in our participation in national diversity charters and awards, including Athena Swan, Carer Positive and the Race Equality Charter.&nbsp;</em></p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;"><em>We particularly welcome applications from people from Black, Asian, minority ethnic and minority religions backgrounds and from LGBTQ+ and disabled people.&nbsp;</em></p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;">&nbsp;</p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;"><strong>Closing date: 17 April 2026</strong></p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;"><strong>Interview date: 11 May 2026</strong></p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;"><strong>Job Description:&nbsp;<a href="https://www.vacancies.st-andrews.ac.uk//ViewAttachment.aspx?enc=jmxpV+AcVus8i/wvT3FZXrrCOvCUGNWd9uca/tGZrAJOxn0uaIw998B27m1Z2faQPrIL0fNvKayeQQ9Vm6dRjh8e9IpvpaUCTN3uAzHFqby4lpmr7kDQu7hbKVYB1s1b" target="_blank" title="AR3262RS FPs.pdf">AR3262RS FPs.pdf</a><br> </strong></p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;"><strong>Ref no: AR3262RS</strong></p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;"><strong>&nbsp;</strong></p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;">School of Biology</p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;">Salary: Grade 6 / &pound;38,784 pa</p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;">Start date: 1 July 2026</p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;">Full time</p> <p style="margin-top: 0px; margin-bottom: 1rem; text-align: justify;">Fixed term: 36 months</p>, Working Hours : Full Time School/Unit : School of Biology Job Family : Academic (Research) ,

Different nontuberculous mycobacteria (NTM) species display unique replication profiles in acidic pH in vitro which correlates to their replication within human macrophages. Inhibition of the acidic ...