Current treatment options for Mycobacterium marinum infections are extensive and challenging. In this work, authors explore the potential of functionalized mesoporous silica nanoparticles as a carrier for delivery of drugs against M. marinum.

Lipids play a critical role in the physiology, life cycle, and pathogenicity of mycobacteria. They largely participate in host–pathogen interactions and fulfill important functions ranging from cell w...

Leclercq et al report the structure of a glycosylated lipooctapeptide (GL8P) produced by Mycobacterium abscessus. GL8P is shown to induce a strong humoral response in infected patients and to…

Background Mycobacterium abscessus is an emerging pathogen causing severe pulmonary infections, particularly in individuals with underlying conditions, such as cystic fibrosis or chronic obstructive p...

This study sheds light into the complex process of intracellular lipid accumulation and storage in the survival and persistence of pathogenic mycobacteria, which is of clinical relevance. By identifying the proteins involved in the formation of ...

Mycobacteria produce a large repertoire of surface-exposed lipids with major biological functions. Among these lipids, trehalose polyphleates (TPPs) are instrumental in the infection of <i>Mycobacterium abscessus</i> by the therapeutic phage BPs. However, while the biosynthesis and transport of TPPs …

Background Mycobacterium abscessus is an emerging pathogen causing severe pulmonary infections, particularly in individuals with underlying conditions, such as cystic fibrosis or chronic obstructive p...

Scientific Reports - Comprehensive pan-genome analysis of Mycobacterium marinum: insights into genomic diversity, evolution, and pathogenicity