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Explore an exciting academic career as a Research Assistant/ Associate in Bacteria-Host Interactions. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

UKRI is updating its grant assessment approach to speed up grant decisions, respond to generative AI and ensure we continue backing the best talent and ideas.

Maset et al. show that bladder conditions strongly influence how urinary tract infections respond to antibiotics and bacteriophages, highlighting the need for more realistic lab models to improve diag...

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Asymptomatic gut colonization is a reservoir for antimicrobial resistance (AMR) such as by the bacterium Acinetobacter baumannii. Geary and Ren, et al., report that A. baumannii evolved a regulator that helps sense competition from the gut microbiota.

Immune responses to urinary tract infections distinguished preterm birth in mice and were linked to birth outcomes in a human pregnancy cohort.

Inside cells, DNA is intimately associated with proteins, forming chromatin. The protein constituents of chromatin vary across the tree of life: histones are the principal building blocks of chromatin...

Transcription underpins the expression of genetic information and is viewed as a series of independent initiation and termination events. In bacteria, promoters and terminators of transcription are th...

In this study, authors investigate the evolution of bacterial resistance to antisense peptide nucleic acid (PNA) antibiotics. They observe that this typically occurs mainly by reducing drug uptake via...

Bioeconomy Assistant Professor The Department of Bacteriology is seeking applicants at the Assistant Professor level to launch a research program in the New Bioeconomy. Applicants may be interested in...

Manchester University

ALT: Liam Gallagher: Oasis Rooftop Walk

Cholera causes severe diarrheal illness in young children, but the mechanisms underlying age-dependent susceptibility remain unclear. Experimental cholera in neonatal mice recapitulates age-dependent ...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

L-type pyocins are a class of bacteriocin-like proteins with antibacterial activity. Here, the authors show that these proteins kill the pathogen Pseudomonas aeruginosa by inhibiting the BAM complex a...

This long-term genomic surveillance identifies a widely disseminated carbapenem-resistant Klebsiella pneumoniae (CRKP) sublineage with enhanced invasiveness but no increased mortality, revealing immun...

Laboratory Manager/Senior Scientist position in the Molecular Mucosal Immunology group at Oxford

In Streptomyces spp., a conserved biosynthetic gene megacluster produces an arsenal of distinct antimicrobials that converge on bacterial biotin biosynthesis as a naturally evolved combination therapy...

Mycobacteria have not yet been reported to engage in interbacterial competition via secretion of proteinaceous toxins. Here, Benedict et al. show that some mycobacteria can use their type-VII secretio...

H-NS is an abundant nucleoid-associated protein found in Enterobacterales species. Some conjugative plasmids encode H-NS homologues, which are thought to facilitate plasmid maintenance and reduce the ...

Abstract. DNA replication and transcription occur simultaneously on the same template, leading to conflicts between the two machineries. Conflicts stall re

Author summary All living organisms require nutrients to grow, survive, and cause disease. Bacteria like Proteus mirabilis, which causes urinary tract infections, rely on specialized systems to import...

To colonize their host and cause disease, enteric pathogens must deploy their virulence factors to establish distinct nutrient niches. How anaerobic p…

Gutierrez et al. show that cholera toxin induces epithelial LDHA-dependent L-lactate production in the small intestine, creating a nutrient niche that Vibrio cholerae exploits through LldD-mediated L-...

Discover an exciting academic career path as a Lecturer (Above the Bar) in Environmental Microbiology & Biotechnology at jobs.ac.uk. Don't miss out on this job opportunity - apply today!

Author summary Extraintestinal pathogenic Escherichia coli (ExPEC) colonise the human gut without causing disease but can disseminate to the urinary tract and bloodstream. Understanding the mechanisms...