New analysis refutes James Watson’s claim he was first to recognize significance of famed photograph 51

Ning Xu - Abnormal beating of airway cilia from a child with Primary Ciliary Dyskinesia (PCD), a genetic disorder affecting respiratory function.

Bulk transcriptome and proteome correlate only modestly, but this has not been investigated in the same cell or across cell-state changes. Here we introduce a scalable technology that quantifies thous...

The complexity of spatial omics data presents analytical challenges and demands substantial computing resources. Here, the authors introduce Sopa, a technology-invariant, memory-efficient pipeline wit...

Gene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores...

Copy number variations (CNVs) drive cancer progression. So far, spatial CNV inference has relied on whole transcriptome-based sequencing technologies. However, advances in image-based spatial transcri...

The spatial organization of tissues emerges from cell interactions across multiple scales, yet current spatial omics analysis tools often emphasize local neighborhoods and may not summarize broader ti...

Wow! It's amazing to see how the Basel Spatial Omics Symposium has grown in recent years. This year, we are holding the third edition. It initially started as a local Microscopy Network Basel event to...

As every year, we celebrated the DBM Best Publication Award during our annual Summer Symposium today. This year, the award has a new name – the DBM Paper Prize – but its purpose remains the same: the ...

Each year, the European Research Council (ERC) awards Starting Grants to support outstanding early-career researchers in establishing ambitious and innovative research programs. We are delighted to an...

GHT-SELEX—high-throughput SELEX with fragmented genomic DNA—shows that transcription factors can be rather particular about which genomic loci they bind, and that C2H2 zinc finger proteins often engage different fingers at different sites.

Thank you for taking the time to complete this Bioconductor developer survey. For the purposes of this survey, "developer" includes package developers as well as contributors involved in…

In a debate that has been building for years, a growing coalition of reformers has concluded that the research project grant (RPG) approach used by many science funders in the United States and based ...

High-dimensional data are visualized through representation on tree structures.

International Journal of Obesity - Rapid and long-lasting remodelling of the blood transcriptome following bariatric surgery

Background Following our previous investigation of 456 articles published by the IHU-Méditerranée Infection (IHU-Mi) institute in Marseille, France, subsequent editorial actions, institutional reviews...

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