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Karen Dixon

@dixon-lab.bsky.social
114 followers 119 following 3 posts

Cancer Immunology Lab in Basel 🇨🇭.

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Karen Dixon @dixon-lab.bsky.social · 26/04/2026
Honoured to be part of this fantastic cohort pushing new directions in cancer research. Excited for what’s ahead!!
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Carolyn King @immunologyking.bsky.social · 06/03/2026
New paper out: HIF-1α+ CD4+ T cells coordinate a tissue-resident immune cell network in the lung www.sciencedirect.com/science/arti...
sciencedirect.com
HIF-1α+ CD4+ T cells coordinate a tissue-resident immune cell network in the lung
A deeper understanding of how tissue-localized immune cells arise and function is critical for developing mucosal vaccines. Currently, there are no mu…
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Jeremy Borniger @jborniger.bsky.social · 15/12/2025
www.cell.com/neuron/fullt... new paper from our group demonstrating how breast tumors dysregulate rhythms in the HPA axis to drive their own growth. Great collaboration with the @corina-amor.bsky.social and @cheadlelab.bsky.social labs @cshlnews.bsky.social
cell.com
Aberrant hypothalamic neuronal activity blunts glucocorticoid diurnal rhythms in murine breast cancer
Gomez, Wu, et al. demonstrate that breast cancer promotes blunted glucocorticoid diurnal rhythms via disinhibition of PVNCRH neurons. Restoration of normal glucocorticoid rhythms via endogenous activa...
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Seth Thomas Scanlon @immunoeditor.bsky.social · 29/04/2025
@dixon-lab.bsky.social, Gonzalo Fernandez Lahore, & @kuchroolab.bsky.social discuss the emerging roles for #TIM3 in regulating #MyeloidCell #immune responses!
science.org
Beyond T cell exhaustion: TIM-3 regulation of myeloid cells
We provide a comprehensive review of 20 years of research on TIM-3 functions in myeloid cells and T cell exhaustion.
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Karen Dixon @dixon-lab.bsky.social · 27/04/2025
Tremendously honoured to be recognised by the AACR among these fantastic scientists - Can't wait to hear more about the phenomenal work is doing! #AACR25 @theaacr.bsky.social
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Ayshwarya Subramanian @ayshwaryas.bsky.social · 10/04/2025
Grateful to share our study on the potential for immune checkpoint blockade in late-onset #AlzheimersDisease out @nature.com today. Co-led with Kimi, Zhuoran, Ahad @kuchroolab.bsky.social in a big team effort @genelayinstitute.bsky.social @broadinstitute.org @harvardmed.bsky.social  /1
nature.com
Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease - Nature
The immune-checkpoint molecule TIM-3 regulates microglial homeostasis, and its microglial-specific deletion reduced cognitive impairment in a mouse model of Alzheimer’s disease.
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Jeremy Borniger @jborniger.bsky.social · 20/03/2025
academic.oup.com/sleep/advanc... excited to share our lab’s first data paper, led by stellar lab tech Leah Boyd in a fun collab with @erinmgibson.bsky.social :) one step closer to understanding and combating chemotherapy-associated behavioral comorbidities.
academic.oup.com
Enduring NREM sleep fragmentation following methotrexate chemotherapy in cancer-naïve mice
AbstractStudy objectives. Sleep disruption is common in people with cancer and survivors, but understanding the mechanisms driving these problems is diffic
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Erin Gibson @erinmgibson.bsky.social · 20/03/2025
A great collab with @jborniger.bsky.social lab showing persistent NREM sleep disturbances with chemotherapy exposure irrespective of cancer presence. Important work in our understanding of how cancer treatments can impart lasting neurological changes.
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Michelle Monje @michellemonje.bsky.social · 19/02/2025
Delighted to share the published version of this work from brilliant #CancerNeuroscience post-doc Tara Barron detailing GABAergic neuron-to-glioma synapses in #DIPG/#DMG. 🧵 Open access link: www.nature.com/articles/s41...
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Toni Choueiri, MD @drchoueiri.bsky.social · 05/02/2025
Our paper in @nature.com is finally published: a prospective trial of a personalized Neoantigen Vaccine in Kidney Cancer www.nature.com/articles/s41... This is teamwork with @danafarber.bsky.social @yalecancer.bsky.social @harvardmed.bsky.social + Wu lab www.nature.com/articles/s41...
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Scheff Research Lab @schefflab.bsky.social · 30/01/2025
📢New publication out: Sensory Neurotransmission and Pain in Solid Tumor Progression! This review article by first author @andremartel.bsky.social details recent work on the bidirectional relationship between sensory neurons and #cancer cells. authors.elsevier.com/sd/article/S... #neurobiology
Proposed cycle between nociceptive input and autonomic output in cancer. Sensitization of nociceptive sensory neurons by the tumor microenvironment leads to propagation of orthodromic signaling towards the central nervous system (CNS).
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