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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 15/09/2026

🏆 Botond Roska and José-Alain Sahel receive the 2026 António Champalimaud Vision Award, the world’s largest prize in vision and ophthalmology. €1 million will support their future research. 🔗 iob.ch/news-insight... #VisionRestoration #IOBBasel #Optogenetics #Ophthalmology

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 26/06/2026

🚀 Warm congratulations to @timayupov.bsky.social, appointed Group Leader at IOB. The new Mitochondrial Biology and Therapy Group studies mitochondrial dysfunction in neurodegeneration and develops targeted mitochondrial therapies using MitoCatch.

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 23/04/2026

Warm congratulations from IOB to Katherine A. High, Jean Bennett & Albert Maguire on the 2026 Breakthrough Prize 👏 Katherine High, CEO of our first spin-off RhyGaze, combines scientific rigor with a clear focus on delivering therapies for vision loss. 🔗 breakthroughprize.org/Laureates/2/...

breakthroughprize.org

Breakthrough Prize – Life Sciences Breakthrough Prize Laureates – Katherine A. High

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 21/04/2026

👁‍🗨We turn science into sight.Congratulations to our Director, Botond Roska, on receiving the 2026 Future Vision Award alongside Connie Cepko & Daniel Ting. 🎬 Watch the short movies: futurevisionfound.org/2026-films #Neuroscience #Vision #Retina #Ophthalmology #Blindness #ScienceInnovation #Eye

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 15/04/2026

💡What if we could reboot sick cells? IOB scientists @timayupov.bsky.social, @vmorenojuan.bsky.social and collaborators led by Botond Roska have developed #MitoCatch, a system that delivers healthy mitochondria directly to diseased cells. A step toward precision mitochondrial medicine. Pic©IOB 🧵👇

Targeted mitochondrial delivery: Extracellular donor mitochondria are delivered specifically to neurons via bispecific protein binders.

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 30/03/2026

👁️ What keeps vision cells alive? A new study just published in Neuron (S. Spirig, @alvaroherreronav.bsky.social et al.) screened 2,700+ compounds across 20,000 lab grown human retinas to find out. 🧵👇

3D retinal organoid, stained.
© IOB, 2026

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 24/03/2026

🤖As deepfakes rise, a chip could bring back trust A new sensor technology secures data at the moment it is captured, making manipulation detectable. Image © Felix Franke, IOB, 2026, generated with AI 🧵👇

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 09/03/2026

👁️‍🗨️Restoring vision: Warm congratulations to our Director and Group Leader Botond Roska who has been awarded the 24th Perl-UNC Neuroscience Prize for developing approaches to decode retinal circuitry and restore vision. #AcademicBlueSky #Neuroscience #Vision #Retina #Ophthalmology #Blindness

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 24/02/2026

🧪 🧫 Photoreceptors depend on exquisitely organised cilia, with disruptions in microtubule regulation compromising retinal health. Beyond providing molecular diagnoses to affected families, this work deepens our understanding of ciliary biology, and highlights why fundamental research matters. #Cilia

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 24/02/2026

📏🔬In collaboration with @computingcaitie.bsky.social and @cellarchlab.com, SAXO6 localization was mapped along ciliary microtubules with direct links to α-tubulin, linking this structural protein class to human retinal disease for the first time. 👉 @ajhgnews.bsky.social #Ophthalmology

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 24/02/2026

🧬 New IRD gene identified! IOB researchers (@abimoye.bsky.social, @mquinodoz.bsky.social, @carlorivolta.bsky.social) found pathogenic variants in SAXO6 (formerly MDM1) in families with a rare late-onset retinal degeneration. 🔗 www.cell.com/ajhg/fulltex... #AcademicBlueSky So what’s SAXO6 doing?

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 24/02/2026

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 09/01/2026

🧬 Major breakthrough: IOB researchers identify new genetic cause of inherited blindness in overlooked RNA genes. The discovery solves decades-old diagnostic mystery and opens new pathways for many patients worldwide. ➡️ www.nature.com/articles/s41... #AcademicBlueSky #Genetics #VisionResearch #IRDs

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 09/12/2025

🌟New hope for vision restoration: Congratulations to Bence György on his 5-year @erc.europa.eu Consolidator Grant. His proposal was selected among 3121 applications from across Europe - a strong vote of confidence in our work at IOB! #ERCCoG #BaseEditing #VisionResearch #Blindness #AcademicBlueSky

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 09/12/2025

🌟New hope for vision restoration: Warm congratulations to Bence György on his 5-year @erc.europa.eu Consolidator Grant to advance base editing for genetic macular degeneration and explore therapies for corneal blindness. #ERCCoG #BaseEditing #VisionResearch #Blindness #AcademicBlueSky

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 30/09/2025

🎉 Big congratulations to @karkam.bsky.social who has just been awarded the PRO RETINA Research Award 2025 for her latest paper in American Journal of Human Genetics! #ResearchAward #AcademicBlueSky #Ophthalmology #MacularDystrophy #Lysosomes #RetinalDisease #VisionResearch #RareDiseases

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 30/09/2025

🚨 CALL FOR APPLICATIONS 🚨 Looking for your next academic step? Join our interdisciplinary IOB MD-PhD / PhD Program to explore the visual system and pioneer therapies for eye diseases. ⏰ Deadline: November 16, 2025 (midnight CET) 🔗 iob.ch/phd-md-phd-program #IOB #Basel #PhDProgram #VisionScience

iob.ch

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 18/09/2025

Can a blind retina be made sensitive to infrared light? Our team shows that an engineered human TRPV1 channel, delivered by AAV, elicits robust responses without foreign proteins or nanoparticles. 🔗 bit.ly/4gt0LO5 #AcademicBlueSky #ProteinEngineering #TRPChannels #SyntheticBiology #Vision #Retina

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Reposted by IOB - Institute of Molecular and Clinical Ophthalmology Basel

IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 17/09/2025

🧬 How can we navigate the genetic complexity of inherited retinal diseases? Our new paper in @ajhgnews.bsky.social presents RetiGene, a curated atlas of IRD genes, built with @erdc-team.bsky.social, to support diagnosis, research and therapy. 👉 bit.ly/467U1S9 #AcademicBlueSky #IRDs #VisionResearch

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 17/09/2025

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 16/09/2025

🔬👁️ Organoids in the spotlight! Magdalena Renner, leading IOB’s organoid platform, shares how high-throughput organoid systems are transforming research and speeding up the path to therapies for eye diseases. Read more: bit.ly/4mquwjP #VisionResearch #HistoBrick #Blindness #Retina #AcademicBlueSky

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Reposted by IOB - Institute of Molecular and Clinical Ophthalmology Basel

Georg Kosche @gek0s.bsky.social · 15/09/2025

Single-cell electroporation is performed via patch pipette and under 2-photon visual guidance in vivo. A short voltage pulse train is applied through the pipette to deliver RNA molecules into a targeted cell. The video below shows this process in cortical neurons expressing GCaMP6s.

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 09/09/2025

👏Warm congratulations to our former IOB postdoctoral fellow @fionamuellner.bsky.social on her new role as Group Leader at @dandrite.bsky.social & Associate Professor at Aarhus University — and on receiving a prestigious ERC Starting Grant! @erc.europa.eu

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 14/08/2025

This changes how we think about vision: timing coordination starts in the eye - not the brain! Check out @anbucci.bsky.social & @ffranke.bsky.social's discovery: nature.com/articles/s41... #Neuroscience #Vision #RGCs #RetinalResearch #AcademicBlueSky #EyeResearch #ScientificDiscovery

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 13/08/2025

🧠👁️ How does your eye prevent seeing a scrambled world? @anbucci.bsky.social and @ffranke.bsky.social reveal the eye's secret "clockwork": bigger axons = faster signals = perfect visual timing! 📖 Full paper nature.com/articles/s41593-025-02011-3 #Vision #AcademicSky #Neuroscience #Retina Image ©IOB

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 13/08/2025

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 04/06/2025

🚨 We are hiring! IOB is looking for an enthusiastic IT career starter (Level 1 Helpdesk) to join our support team. Whether you are a student, graduate, or making a career change, this entry-level role is a great opportunity to launch your path in IT. Interested? 👉 iob.ch/join-iob/ope... #AcademicSky

iob.ch

Open Positions: IOB

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 13/05/2025

🧬👁️Discover how research and patient care come together in the latest Novartis Live magazine — with stories from the labs and clinics shaping the future of vision. 🔗 bit.ly/4km6XZ0 #IOB #VisionScience #TranslationalResearch #Basel #Ophthalmology #AcademicSky #Novartis

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 08/05/2025

🔬 We are hiring! Research Assistant/Associate (100%) – Molecular Mechanisms of Myopia 📍 Location: Basel 🧪 Background in molecular biology, genomics, neuroscience or related field 💼 Full-time position Apply now or share! iob.ch/join-iob/ope...

iob.ch

Open Positions: IOB

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 16/04/2025

What controls eye growth? 10 key insights from decades of myopia research - from retinal feedback to red light therapy, here is what we know: 🔗 onlinelibrary.wiley.com/doi/10.1111/... #Myopia #VisionResearch #Ophthalmology #GlobalHealth #AcademicBlueSky Image © IOB, generated with Google AI, 2025

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 15/04/2025

🧬IOB researchers (@Mukhtarullah.bsky.social @karkam.bsky.social @carlorivolta.bsky.social @mquinodoz.bsky.social) and international team uncover genetic signatures of eye diseases in Pakistan 📖 doi.org/10.1038/s415... #Genetics #Vision #AcademicSky Image © IOB, generated with Google AI, Gemini

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 21/03/2025

🧠 Brain efficiency doesn't need perfect organization Random neural responses can lead to better information processing than precisely tuned ones. www.sciencedirect.com/science/arti... @ravadasilveira.bsky.social | image © IOB, 2025 #AcademicSky #Neuroscience #ScienceNews

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 24/02/2025

🧠 How does your brain create mental maps? New research reveals a surprisingly simple mathematical principle behind complex spatial representations! From rodents to bats, same rules apply 🐁🦇 #Neuroscience #BrainScience #ScienceNews #AcademicBluesky Read more here: www.cell.com/neuron/fullt...

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Tamas Dalmay @tdalmay.bsky.social · 12/02/2025

How do different sensory signals combine in the computation of cognitive maps? I’m thrilled to share our new preprint, in which we investigate this question in the context of the head-direction system: www.biorxiv.org/content/10.1...

biorxiv.org

Joint visual-vestibular computation of head direction and reflexive eye movement

Several cognitive maps have been identified, but what sensory signals drive them and how these are combined are not well understood. One such map, the head-direction representation, is believed to be ...

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 11/02/2025

🔍 Did you ever wonder why your eyes make tiny movements even when trying to hold still? Those movements are not a bug, they are an essential feature for sharp vision! Here is why: www.pnas.org/doi/epub/10.... #AcademicSky #Neuroscience #Ophthalmology Illustration ©IOB, 2025

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 21/01/2025

👁️ Advancing Vision Research 👁️ Our latest study with collaborators from CSEM introduces a HistoBrick array made from a novel material mix, optimizing cryosectioning and immunohistochemistry for retinal organoids and small tissues. 📖 Learn more: rdcu.be/d5o8Z #Organoids #AcademicSky Picture © IOB

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University of Basel @unibas.ch · 09/01/2025

A research team from @iobswiss.bsky.social and the University of Basel has developed a therapy to treat Stargardt disease, which often leads to vision loss. Its study shows promising results using a precise technique for gene correction.

unibas.ch

Precision gene editing could prevent vision loss from Stargardt disease

Researchers have developed a therapy to treat Stargardt disease, the most common form of inherited macular degeneration, which often leads to vision loss. Their study shows promising results using a p...

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 21/01/2025

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 10/01/2025

We are pleased to share that RhyGaze, IOB's first spin-off, has secured Series A funding with an USD 86 million investment to advance vision restoration therapy. Read more: iob.ch/news-view-al... #Biotech #Basel #Innovation #LifeSciences #GeneTherapy #Ophthalmology #RhyGaze #BioTechHub

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 08/01/2025

✨Thrilled about our new publication in Nature Medicine! We are excited to offer a potential new avenue for treating Stargardt disease! Read the paper here: nature.com/articles/s41... Watch the video: iob.ch/fileadmin/ge... Press release here: iob.ch/news-view-al... © 2025 IOB

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 08/01/2025

✨Scientific breakthrough: IOB researchers have achieved a significant advance in developing a new treatment for Stargardt disease, the most common form of inherited macular degeneration. Read more: www.nature.com/articles/s41... Watch full movie: iob.ch/news-view-al... #AcademicSky #neuroscience

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IOB - Institute of Molecular and Clinical Ophthalmology Basel @iobswiss.bsky.social · 08/01/2025

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