Cell-cycle remodeling is fundamental to pluripotency and lineage commitment, yet whether its transcriptional and post-transcriptional architecture is conserved across species and developmental states ...

The following will be offered in this call:Up to 8 FPI positions associated with the “Proyectos de Generación de Conocimiento 2025” Call (funded by the Agencia Estatal de Investigación AEI- MICINN).Ch...

Muscle function depends on the ability of myofibrils to withstand and repair mechanical damage, yet how adult muscles remodel damaged myofibrils remains poorly understood. Here, we establish a Drosoph...

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A renowned scientist at UMass Chan Medical School is moving his lab to Canada. The Canadian government named RNA researcher Phillip Zamore among the first recipients of awards that will total more tha...

Popular vendors’ catalogs feature more than 18,000 manipulated images

Derived from patient tumor samples and available to researchers around the world, the cells will aid the development of new cancer treatments.

Super-fast and accurate demultiplexing of direct RNA-seq runs (Pryszcz*, Diensthuber*, et al., Genome Res 2025) - novoalab/SeqTagger

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Super-enhancers have been proposed to cluster in the nucleus when compared to other genomic elements. Le et al. found that super-enhancer clustering was rare and driven by non-specific interactions. P...

While cancer looms large in the public and scientific minds, this can result in a quite narrow view of its range and manifestations. The centering of human clinical investigations and the popularity o...

Background Following our previous investigation of 456 articles published by the IHU-Méditerranée Infection (IHU-Mi) institute in Marseille, France, subsequent editorial actions, institutional reviews...

Mutations found in Colombian families raised hopes for treatments. Altered patient data and suspect images call their benefits into question

Richa et al. show that Notch signaling and cell mechanics work together to ensure the robust selection of a single neural precursor that never initiates Notch-dependent transcription. One cell is bias...

Adult intestinal size plasticity is driven not only by epithelial stem cells but also by remodeling of the surrounding visceral musculature. Sex- and reproduction-dependent muscle remodeling controls ...

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Beyond telomere protection, TRF2 couples stem cell identity to regenerative repair through lineage-specific gene regulation.

The Wnt family ligands carry a lipid moiety that must be shielded from the aqueous environment. During secretion, this is achieved by the cargo receptor Wntless. The effect of acute endocytosis inhibi...