Ivy League universities have dominated recent news headlines, having become popular targets for critics of higher education. But the threats they face—cuts to federal research funding, assaults on aca...

A decade on from the launch of an ambitious project, it’s time to revisit the reasons for constructing a human genome from scratch.

A functional screen reveals phage sponge proteins that bind Pycsar, Thoeris and CBASS signalling molecules to inhibit bacterial immunity.

Posted on behalf of the Swiss National Reference Center for Emerging Viral Infections, Geneva University Hospitals and the Institute of Medical Virology, University of Zurich (Partner Laboratory Natio...

A minimal PyTorch re-implementation of AlphaFold2's model & training - ChrisHayduk/minAlphaFold2

The mitochondrial oxidative phosphorylation system powering most aerobic organisms is typically depicted as two spatially segregated machineries(1): electron transport chain complexes I-IV (ETC CI-CIV

Hanahan revisits the evolving framework of cancer hallmarks, synthesizing 25 years of conceptual refinement into a multidimensional view of tumor biology. This review highlights how aberrant capabilit...

The EMBO Journal - Cell division involves the complete reorganization of the cellular architecture, requiring precise coordination of cellular processes in space and time, but how does this control...

Mirdita Lab builds scalable bioinformatics methods.

EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.

Intrinsically disordered proteins can aggregate in many distinct conformations (polymorphs). Polymorphs are a striking example of fold-switching: one primary structure able to form distinct tertiary s...

Marglous et al. generated a database of anti-glycan antibody sequences, expressed and characterized a library of 154 antibodies, and generated DNA-barcoded antibodies for single-cell transcriptome and glycome profiling. Glycans associated with cancer stem cells and metastasis were uncovered, demonstrating utility for basic and clinical research.