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Ján Bíňovský

@jbinovsky.bsky.social
1.1K followers 1.3K following 62 posts

Postdoc @MPI of Biochemistry, Sokolova Lab 🇩🇪 | PhD @CEITEC_Brno, Plevka Lab 🇨🇿 | biochemistry & structural biology 🧬🔬

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Ján Bíňovský @jbinovsky.bsky.social · 27/09/2026
Passing this along, because I am genuinely curious about answers.
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Ján Bíňovský @jbinovsky.bsky.social · 23/09/2026
Note to self: Do not work late just because of the view! #postdocsky
View through an open laboratory window at sunset. Pink and orange clouds stretch across a pale blue sky above the dark silhouettes of trees and nearby buildings.
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Ján Bíňovský @jbinovsky.bsky.social · 04/09/2026
Phages are weird. Some have T replaced by U in their DNA. In my new role as a #postdoc in Maria Sokolova’s group at the @mpibiochem.bsky.social, I’ll investigate how their transcription machinery recognizes and reads this unusual genome 🧬 1/2
Selfie of a man in a red sweater standing outside the Max Planck Institute in Martinsried. Behind him, a large black wall sign reads “max-planck-institute martinsried” and “biochemie biologische intelligenz.”
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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 14/07/2026
A beautiful journey through the nuclear pore complex with #cryoET - samples prepared via the Arctis Cryo-Plasma-FIB, data collected with the Glacios Cryo-TEM and segmented in Amira Software. #TeamTomo - See what’s possible with 200 kV cryo-ET: ter.li/n2a8i5po
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Ján Bíňovský @jbinovsky.bsky.social · 10/07/2026
"Why paying peer reviewers works, according to a journal’s editor-in-chief" I wonder if this is going to change anything.....old idea, new data, uncertain impact. Your thoughts? www.nature.com/articles/d41...
nature.com
Why paying peer reviewers works, according to a journal’s editor-in-chief
A biology journal that paid peer reviewers found that the approach cut the time to a first editorial decision by 85% and maintained high-quality reviews.
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Ján Bíňovský @jbinovsky.bsky.social · 02/07/2026
🔥My first (co)first-author paper is out🔥 The surfaces of Gram+ and Gram- bacteria are markedly different from each other. How are phages equipped to breach the Gram+ envelope❓ 💡We report a baseplate structure uniquely adapted to infect Gram+ S. aureus. A 🧵⬇️ 1/8 #phagesky #cryoEM 🧪
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Ján Bíňovský @jbinovsky.bsky.social · 19/06/2026
I love when real life issues get explained by science (scientists) so elegantly 👏🏻
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Microbes.Info @microbesinfo.bsky.social · 10/03/2026
High-Resolution #virus blueprint offers new hope against #antibiotic resistance ... | #antibioticresistance | #bacteria | #bacteriophages | #phage | By @universityofotago.bsky.social via scitechdaily .com
scitechdaily.com
Stunning High-Resolution Virus Blueprint Offers New Hope Against Antibiotic Resistance
A detailed 3D map of a bacteria-hunting virus reveals ancient origins and new promise against superbugs.
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Aritz Roa-Eguiara @aritz-roa.bsky.social · 07/03/2026
🚨Preprint! Happy to share the research from my PhD “Genome delivery of a contractile tailed phage and its superinfection exclusion mechanism”. We use cryoEM to study the genome ejection of the phage T4, revealing how the tape measure protein regulates the process. www.biorxiv.org/content/10.6...
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Ján Bíňovský @jbinovsky.bsky.social · 19/05/2025
Much needed addition to the AlphaFold Database! 💻 Large potential for use in #StructuralBiology #Phage research.
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Ján Bíňovský @jbinovsky.bsky.social · 28/04/2025
Always happy to provide "wonderfully bad mmCIF files" to make #chimeraX better!
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Ján Bíňovský @jbinovsky.bsky.social · 18/04/2025
Nice work and awesome #scicomm thread!
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Ed Hutchinson @socialinfluenza.bsky.social · 30/01/2025
Our study on pasteurising influenza viruses in milk is now out! It's a nice simple story: influenza viruses (including H5N1) are killed really effectively by pasteurisation, but in raw milk they stay infectious - obvious public health implications of both points... (1/2) rdcu.be/d73te
A picture of a Fresian cow whose markings resemble influenza viruses
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Rita Strack @ritastrack.bsky.social · 22/01/2025
I'd like to draw your attention to this truly excellent paper from the Taraska lab on cryoET of plasma membrane associated proteins. Everyone who is thinking about probes in the cryoET space should also see what they could do with ferritag (fig 6) www.nature.com/articles/s41...
This is a scientific figure from the paper mentioned in the post. It shows fluorescence and electron microscopy images and associated schematics for using the ferritag to image clathrin coated pit proteins.
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Ján Bíňovský @jbinovsky.bsky.social · 13/01/2025
I appreciate the stats! Thanks, @pdbeurope.bsky.social for a summary!
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Janet Iwasa @jiwasa.bsky.social · 07/01/2025
I'm happy and humbled to take on a new role with @rcsbpdb.bsky.social. I'll be continuing David Goodsell's work on the Molecule of the Month, starting with my first article on Assembly Line Polyketide Synthases! Check it out (animation included!) pdb101.rcsb.org/motm/301
pdb101.rcsb.org
PDB101: Molecule of the Month: Assembly Line Polyketide Synthases
Large multienzyme complexes that synthesize diverse small molecules in a stepwise manner.
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Ján Bíňovský @jbinovsky.bsky.social · 06/01/2025
Amazing work and resource! 😍
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Fabian Eisenstein @eisfabian.bsky.social · 17/12/2024
SPACEtomo v1.2 is online! github.com/eisfabian/SP... - Improved GUIs for lamella detection, target selection and CLEM registration make it the best target selection workflow for PACEtomo on any kind of lamella sample. - Easier installation and configuration Any feedback is much appreciated! :)
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Ján Bíňovský @jbinovsky.bsky.social · 17/12/2024
🎄Xmas office cleaning 🗑️ ...and how do you organize your thoughts? 🫵 #PhDlife #PhDSky #mindmap
The image is a mind map drawn on white paper, used for organizing thoughts before writing a paragraph. It contains various interconnected words and phrases, with many items circled, underlined, or checked off using green and red pens. Some words and phrases are marked with red circles, possibly indicating key points, while others have green checkmarks denoting completion. Additional notes and arrows are scattered across the sheet, suggesting a workflow for developing ideas. The lower section includes handwritten notes in red and green ink, outlining tasks like measuring angles, verifying structures, and calculating specific parameters.
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Ján Bíňovský @jbinovsky.bsky.social · 11/12/2024
I knew it wouldn't be long before we see #cryoEM structures of a #phage cousin infecting #Archea 🦠 🧪 Beautiful structures from @daumlab.bsky.social, congrats!
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Ján Bíňovský @jbinovsky.bsky.social · 22/11/2024
Dear #StructuralBiology #PhD #PostDoc peers, join in!
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Ján Bíňovský @jbinovsky.bsky.social · 15/11/2024
Another useful starter pack 👇
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Ján Bíňovský @jbinovsky.bsky.social · 14/11/2024
In case someone is looking for this...
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Ján Bíňovský @jbinovsky.bsky.social · 08/11/2024
Just uploaded a revised version of the manuscript on bioRxiv 🙌 We made some changes to the text and figures, mainly to clarify the naming of proteins. Yeah, it's a challenge to describe things within two different 10MDa structures 🐘
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Ján Bíňovský @jbinovsky.bsky.social · 23/09/2024
🚀Announcing my first (co)first-author manuscript 🚀 "Cell attachment and tail contraction of S. aureus phage phi812" 🔗 bit.ly/Phi812 Explore the structural details of phage interaction with Gram+ bacteria 🤯 #PhageTherapy #cryoEM 🧪 | 🧬🧶 | 🦠 1/11
bit.ly
Cell attachment and tail contraction of S. aureus phage phi812
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Ján Bíňovský @jbinovsky.bsky.social · 08/08/2024
Reading a lot about contractile phages and injection systems, the idea of leveraging them for cargo delivery always amazed me 🤯 and it's no longer just an idea 🧪 Here, a T. gondii secretion system was hijacked to deliver therapeutic proteins to neurons. Link to study: rdcu.be/dQozB
rdcu.be
Engineering Toxoplasma gondii secretion systems for intracellular delivery of multiple large therapeutic proteins to neurons
Nature Microbiology - Toxoplasma gondii secretion systems can be engineered to deliver multiple large therapeutic proteins to neurons in vitro and in vivo.
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Ján Bíňovský @jbinovsky.bsky.social · 31/07/2024
Using MS Word's "Dictate" function these days: "I did an internshit..." "I learned to cry electron microscopy" ...how am I supposed to write a motivation letter with this? 😢
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Kristian G. Andersen @kgandersen.bsky.social · 05/07/2024
Really good 15 min TWiV episode with Paul Offit outlining how false and irresponsible the recent lab leak nonsense from @nytimes.com is. I for one appreciate the brevity - there really is nothing more to it. If you're interested in the topic, give it a listen. www.youtube.com/watch?v=Ukv9...
youtube.com
Beyond the Noise #40: Lab leak mania
In this episode Dr. Offit asks, why did the New York Times publish an op-ed supporting the lab leak theory when all evidence supports a zoonotic spillover?Sh...
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Ján Bíňovský @jbinovsky.bsky.social · 02/07/2024
Manuscript submitted 🤞 Brace for new structural insights into a bacteriophage landing onto the host cell 🚀
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Ján Bíňovský @jbinovsky.bsky.social · 22/03/2024
📰 I find myself questioning my scientific career from time to time. This is an encouraging piece. "Meaningfulness in a scientific career is about more than tangible outputs." www.nature.com/articles/d41...
nature.com
Meaningfulness in a scientific career is about more than tangible outputs
Letter to the Editor
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Ján Bíňovský @jbinovsky.bsky.social · 21/03/2024
Just finished registration for the Gordon Research Seminar (GRS), complementing the conference (GRC) on 3D #ElectronMicrocopy 🔥 Looking forward to attending the GRC/S for the first time! Am I gonna meet someone from my BlueSky bubble? 🙌
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Ján Bíňovský @jbinovsky.bsky.social · 15/02/2024
📰 Some positive news for the afternoon reading: a survey about trust in scientists. "...trust levels are fairly high across a range of demographics." "It’s about the leadership of political parties and how they treat scientists." www.nature.com/articles/d41...
nature.com
Largest post-pandemic survey finds trust in scientists is high
Study of more than 70,000 people suggests that trust levels vary among countries and are linked to political orientation. Study of more than 70,000 people suggests that trust levels vary among countri...
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Kaitlyn Abe @kaitlynabe.bsky.social · 09/02/2024
I am excited to share that my work with @cijilim.bsky.social on protecting fragile samples from air-water-interface damage during cryo-EM plunge freezing is in preprint! www.biorxiv.org/content/10.1...
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Ján Bíňovský @jbinovsky.bsky.social · 07/02/2024
POV: renaming protein chains in your model. Symmetry mates not included.
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Ján Bíňovský @jbinovsky.bsky.social · 01/02/2024
🚨 Scientific Illustrator Needed 🚨 I'm seeking a skilled illustrator to visualize a cool phage structure using molecular animation in 3D, ideally something dynamic, if possible. Please share and drop suggestions! What details should I provide initially, and what are typical timelines & costs?
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Ján Bíňovský @jbinovsky.bsky.social · 29/01/2024
My colleague, a structural biologist skilled in cryoEM and cryoET, is looking for a postdoc in 🇪🇺 Despite her outstanding CV, apparently, 🇷🇺 passport seems to be a hurdle. Any recommendations for open-minded institutions? x.com/LMumrik/stat...
x.com
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