The development of compact and efficient CRISPR-Cas systems is crucial for biomedical and therapeutic genome editing, particularly in vivo applications based on viral delivery. Here, we performed a co...

The ability to discriminate thousands of odors in our environment requires each olfactory neuron to express a single olfactory receptor from hundreds of available genes. The biochemical mechanism enfo...

The control of transcription factor (TF) concentrations is crucial for the precise regulation of gene expression and cell fate decisions during development. Yet, TF concentrations can display substant...

imageimagePaternal environmental exposures have been linked with modulation of phenotype and disease risk in offspring via largely unclear mechanisms. This study employs in vitro fertilization and sin...

Dynamic gene regulation requires precise cooperation between transcription factors and chromatin modifiers at regulatory elements to achieve not only activation or repression, but also appropriate tra...

We are seeking to recruit a highly motivated scientist to establish and lead an independent research laboratory at the EMBL Epigenetics and Neurobiology Unit in Rome. EMBL provides a unique environmen...

We offer a wide range of challenging scientific and non-scientific positions at all of our European locations and encourage applications from international candidates at all career levels.

Nature - Disturbances in the gut microbiota of male mice manifest as fitness defects in their offspring by affecting plancenta function, revealing a paternal gut–germline axis.

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The 2025 Gordon Research Conference on Developmental Biology will be held in Pomona, California. Apply today to reserve your spot.

Sex chromosomes are emerging as key regulators of adult health and disease in males (XY) and females (XX), but their impact on embryo development is poorly understood. Using single-cell RNA sequencing...

The graduate program IMPRS for Biology And Computation (IMPRS-BAC) provides an education for students at the interface of molecular life sciences and computational sciences. This is based on perspective and supervision from both ends - experimental and computational - and suits students with degrees in molecular biology, biochemistry, mathematics, bioinformatics or any related areas. If you have a passion for epigenetics, bioinformatics, developmental biology, mathematics, sequence analysis, gene regulation, RNA biology, mechanobiology, protein biochemistry, stem cells and differentiation, statistics, molecular evolution or biophysics and want to work at the Max Planck Institute for Molecular Genetics or the Freie Universität Berlin - this is the program for you!

The paternal preconception environment has been implicated as a modulator of phenotypic traits and disease risk in F1 offspring. However, the prevalence and mechanisms of such intergenerational epigen...

Nucleosomes at actively transcribed promoters have specific histone post-transcriptional modifications and histone variants. These features are thought to contribute to the formation and maintenance o...

The principal objective of DANIO-ReCODE is to provide world-class doctoral training to a new generation of early-career researchers interested in understanding the complex and multilayered process of ...

Developmental Dynamics of Tissue Formation