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Ayele Argaw-Denboba

@denbobalab.bsky.social
259 followers 410 following 1 posts

Gut microbiota, Developmental metabolism, Epigenetic inheritance|Group Leader@MPI-IE

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Reposted by Ayele Argaw-Denboba
Bork Group at EMBL Heidelberg @borklab.bsky.social · 19/12/2024
As an "EIPOD" interdisciplinary postdoc in @jamiehackett.bsky.social and our lab, @denbobalab.bsky.social found that "Paternal microbiome perturbations impact offspring fitness" (2024): antibiotic treatment of male mice led to low birth weight & higher mortality in offspring www.nature.com/artic...
nature.com
Paternal microbiome perturbations impact offspring fitness
Nature - Disturbances in the gut microbiota of male mice manifest as fitness defects in their offspring by affecting plancenta function, revealing a paternal gut–germline axis.
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Reposted by Ayele Argaw-Denboba
Max Planck Institute of Immunobiology and Epigenetics @mpi-ie.bsky.social · 07/12/2024
The Epigenetics Meeting in Freiburg is known for being pretty packed. Thus, right after the keynote by Patrick Cramer, we continued with Rob Martienssen, Hiten Madhani @hitenmadhani.bsky.social, Valérie Hilgers, Ayele Denboba @denbobalab.bsky.social as well as Yoichi Shinkai from RIKEN.
Rob Martienssen (CSHL) and Yoichi Shinkai (Riken)Hiten Madhani (UCSF): »Epigenetic memory over geological timescales«Valérie Hilgers and her lab investigate the molecular mechanisms underlying neuron-specific RNA signatures. The lab aims to understand how RNA processing affects neuronal development and functionAyele Denboba: »Modelling epigenetic inheritance through gut microbiota-germline interactions« /// The lab aims to decipher the regulatory role of gut microbiota in gametogenesis, embryogenesis, epigenetic inheritance mechanisms, and identify microbiome-sourced metabolites that regulate chromatin functions.
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Ayele Argaw-Denboba @handle.invalid · 02/12/2024
Highly recommend - exciting project and best mentor to grow as a scientist!👇
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Reposted by Ayele Argaw-Denboba
Jamie Hackett @jamiehackett.bsky.social · 02/12/2024
Postdoc positions in epigenetics! We have several opportunities to investigate big picture questions on (epi)genome function & mechanisms Based @embl.org near Rome (Italy), we offer full scientific support/facilities, training & funding. Also...☀️🏛️🍕🏖️ See👇or contact me for other options. Pls RS
Advert detailing a postdoctoral scientist position at EMBL Rome. Contact: jamie.hackett@embl.it
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Reposted by Ayele Argaw-Denboba
Jamie Hackett @jamiehackett.bsky.social · 28/11/2024
Starter packs are fab, but skew towards established folks Cue intros into all the amazing people in our lab… give them a follow 🚶 First up Marzia Munafo. Leading a spectacular oocyte epigenomics project (watch this space 👀) and science illustrator extraordinaire. Check out the beautiful works 👇👇
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