iiinova — where your digital self keeps evolving

Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 12/09/2026

Wonder if it is a coincidence that the documentary movie titled NAZA, on Israel’s preempted AI-assisted genocide against Palestinians, rhymes not only with GAZA, but also with NAZI.

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 26/08/2026

Yoshiki Sasai, another scientist who made a mistake & took his life from the onslaught of media. His death allows the community to continue "robbing" him from being credited for making the 1st brain organoids already in 2008-2011. e.g. sciencedirect.com/science/arti... nature.com/articles/nat...

sciencedirect.com

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 22/08/2026

MUST READ: "The question is not simply whether our institutions can open their doors to racialised people. It is whether, they r afforded the same freedom to be individuals that others take for granted: to succeed, to struggle, to make mistakes, to be held accountable proportionately,...to belong."

mentalhealtheurope.org

When scrutiny exposes a double standard: Jason Arday, racism and the cost to mental health - Mental Health Europe

Written by Nabil Sanaullah, MHE Communications Manager, and Ann-Katrin Orr, MHE Policy Officer The death of Professor Jason Arday, who it appears took his own life at the age of […]

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 22/08/2026

First time i see this & i LOVE it! - option of writing an author name in a paper also in ARABIC!

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 27/07/2026

Enjoyed r summarizing this important & reproducible (yes we tried it) paper on how DMSO is sufficient to induce human balstoids from human naive PSCs, emphasizing (again) the great importance cell state has on embryo models formed. Congrat to Mo Li group & @KAUST . www.nature.com/articles/s41...

nature.com

Signaling-independent boosting of human blastoid formation - Cell Research

Cell Research - Signaling-independent boosting of human blastoid formation

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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 09/06/2026

"Humbled to receive this recognition. This belongs as much to my team, my family, & to my home, Palestine: the people, the place, the joyful stubbornness to enjoy life." Cheers buddy @gautamdey.bsky.social Thx to my mentors @sophiemartinlab.bsky.social, @paveltomancak.bsky.social, & Pierre Gönczy.

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Nicolas Rivron @nicolasrivron.bsky.social · 11/04/2026

Hi all! 👋 leeboratory.bsky.social and I are recruiting a VIP³ postdoc to join our teams and decode the genetic logic of how blastoids transit to the post-implantation stage. MolBio, genetics and computational approaches. If this sounds like you (or someone you know), we’d love to hear from you! 🚀

leeboratory.bsky.social

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 05/04/2026

This is another sad Easter for us. Decided to spend it in the lab to be with my team relentlessly coming to lab. Trying to raise our spirit again while blasting the famous Fairouz Sung Recital for Easter, enchanting magical voice with Greek Orthodox inspired chanting. www.youtube.com/watch?v=eiLa...

youtube.com

Ya Mariyam El Bekr

YouTube video by Fairuz - Topic

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 29/03/2026

The Hanna lab Tissue Culture squad is not shaken by the sirens … we developed many tricks how to walk to the shelter and run back quickly before the cells are over trypsinized :)

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 14/03/2026

1/3 "LET's LIBERATE the IRANIAN GAYS FROM THEIR REGIME"!! I am really still surprised that the Great liberating Nations on this Earth Israel ( the ethno-zionist occupier and ethnic cleanser of 7 million oppressed and rightless palestinians since 80 years) and the USA ...

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 03/03/2026

#Escapism: when you insist on having your new lab office reading armchair installed the week your pre-validated lab coordinates for missile targeting may get validated again any minute :)

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 22/01/2026

1/n A Message from the Arab Students and Researchers Regarding Joining the General Strike against Organized Crime Dear Weizmann Institute Community, The Arab community is currently enduring one of the harshest periods in recent years.

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 25/10/2025

MIT Technology Review article about our research on human embryo models in this day & age. I didn't agree to interview because what i find as over-sensational writing style & i disagree with several things.. BUT Antonio managed to put together an interesting mix of events and ideas worth reading.

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 04/10/2025

Last day of intense science discussions and presentations at the HFSP Science Summit Japan was held in Kyoto university. It has been an amazing 5 days of listening to great scientists from Japan and all over the world. An unforgettable visit.

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 03/10/2025

Another great day in Japan science summit with Intriguing science and science policy discussions at University of Tokyo.

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 03/10/2025

Finally .. incredible much awaited wok on deriving avian naive ESCs “Derivation of embryonic stem cells across avian species” www.nature.com/articles/s41...

nature.com

Derivation of embryonic stem cells across avian species - Nature Biotechnology

Embryonic stem cells for chicken and seven other avian species are derived.

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 28/09/2025

EEE meeting is BACK! Early Embryogenesis & Epigenetics conference in Berlin 02/2026. Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open - w.molgen.mpg.de/embryo2026

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Denis Duboule @denisduboule.bsky.social · 19/09/2025

Having fun @amartinezarias.bsky.social party! 🙏🏻🎉💐 Great meeting #InHoxWeSortOfTrust

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Human Frontier Science Program @hfspo.bsky.social · 03/09/2025

🧪 HFSP & partners present Science Summit Japan 2025! 🗓️Oct 1–4 📍Tohoku University, RIKEN, UThe University of Tokyo & Kyoto University. ✨ Nobel Laureates, HFSP Nakasone Awardees & top researchers engaging with young scientists. More info 👉https://bit.ly/45WGRWM

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 28/08/2025

Shout out re @isscr.org awards nomination deadline SEP 30 2025! Please note the great revision & efforts that have been made to recognize excellence in industry, policy makers, clinical translation etc & from across the globe. Self-nominations are equally welcomed! www.isscr.org/awards

isscr.org

Awards + Nominations — International Society for Stem Cell Research

The ISSCR Awards portfolio recognizes outstanding achievements and research potential in the field of stem cell research around the world. The ISSCR awards honor scientists’ innovative work to harness...

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 14/08/2025

Tnx to @hfspo.bsky.social for humbling opportunity to present our work #HFSPNakasoneAward lecture. Tnx to Hanna lab, current & former members, collaborators, mentors. @weizmanninstitute.bsky.social for critical backing, @isscr.org for guidelines, funding agencies & dear philanthropists for funding

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Marta Shahbazi @marta-shahbazi.bsky.social · 09/08/2025

🤩 Very excited to share our new work! We have derived euploid and aneuploid trophoblast organoids and extra-embryonic mesoderm cell lines from early human embryos. In doing so, we have characterised the tissue requirements for their specification. If you want to know more, continue reading….

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Harmit Singh Malik @harmitmalik.bsky.social · 06/08/2025

To have this paper appear the same day that RFK Jr is canceling all mRNA vaccine funding is further indication that irony is not dead, even though we might all be soon.

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 05/08/2025

1/n Dear friends, in light of the current events in Palestine and to help spread awareness, a large number of filmmakers have made their FILMS about PALESTINE AVAILABLE FOR ONLINE FOR FREE Below, we are sharing links to films that you can watch and share to spread our message to the world:

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Nitzan Gonen @nitzan-gonen.bsky.social · 27/07/2025

1/n Very excited to share our recent paper published on @ScienceAdvances where we dissect the gene regulatory landscape guiding mouse sex determination! science.org/doi/10.1126/... A huge well done to @IsabelleStevant.genomic.social.ap.brid.gy, Meshi and Elisheva who spearhead this project!

science.org

The gene regulatory landscape driving mouse gonadal supporting cell differentiation

Multiomics analysis revealed the regulatory elements and transcription factors responsible for gonadal sex determination.

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Megan Molteni @mmolteni.bsky.social · 14/07/2025

Fascinating story today from @levfacher.bsky.social about a rehab center where patients are currently being treated for substance use disorder with GLP-1 drugs — even as clinical trials measuring their effectiveness as anti-addiction medications remain years from reading out data.

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Camp Lab @graycamplab.bsky.social · 11/07/2025

Neuron programming! Pro-neural TFs + 480 morphogen conditions + scRNA-seq --> Diverse iN subtypes of forebrain, midbrain, hindbrain, spinal cord, and PNS. @hsiuchuanlin.bsky.social‬ @jasperjanssens.bsky.social‬ and Treutlein Lab! @science.org www.science.org/doi/10.1126/... #NGN2 #ASCL1

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Human Frontier Science Program @hfspo.bsky.social · 09/07/2025

🎉 Full house in Melbourne for the kickoff of the 24th HFSP Awardees Meeting! Congrats to @jacob-hanna.bsky.social, 2025 HFSP Nakasone Awardee, who was honored at today’s ceremony. Let the science begin! 🧪 #HFSPmtg2025 #NakasoneAward #sts

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 23/06/2025

Fantastic work from @bulutkarslioglu.bsky.social group. we r happy to contribute on the role of hypoxia in proper gastrulation ex utero as originally noted in Aguilera-Castrejon et al. Nature 2021 for robust gastrulation. Now this is shown to be important for taking gastruloids to the next level.

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 18/06/2025

These r very sad days for me & colleagues @WeizmannScience & many civilians in our region. Yet, i am also stoked to be the 2025 recipient of the Nakasone Award by the Human Frontiers - HFSP. I would have never imagined in my wildest dreams to be on such a list. Tnx! www.hfsp.org/hfsp-nakason...

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 15/06/2025

After being stuck in Hong Kong after ISSCR meeting unable to fly back home, I managed to get on a plane to London to stay with family, only to learn in the air that our institute was hit. My team is all safe. My lab sustained serious blast damage but we shall overcome! #PeaceNow tnx for messages :)

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 13/06/2025

thanks and also for a great meeting and great podcasts.

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James Briscoe @jamesbriscoe.bsky.social · 15/05/2025

Beautiful work from @santoslab.bsky.social A 3D model of human amnion from hESCs These recapitulate amniotic sac development, revealing GATA3 as key amniogenesis driver & autoregulatory BMP/Wnt feedback loops And check out the size of them in the video www.cell.com/cell/fulltex...

cell.com

Post-gastrulation amnioids as a stem cell-derived model of human extra-embryonic development

An embryonic stem cell-based 3D model that accurately recapitulates the size, morphology, and functional features of the human amnion at 4 weeks, termed the post-gastrulation amnioid (PGA), is develop...

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 05/05/2025

We truly enjoyed summarizing this tour de force work in Developmental Cell on understanding human cleavage stage ZGA arrest by using single-embryo single-cell allele-specific RNA-seq by Peng Yuan team, & catching up on other recent advancements in ZGA research. www.cell.com/developmenta...

cell.com

Human-specific contributors to cleavage-stage embryonic arrest during maternal to zygotic transition

Understanding the functional regulatory landscape of maternal-to-zygotic transition (MZT) during early human embryo development remains a challenge. In this issue of Developmental Cell, Guo et al. ass...

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 28/03/2025

Saddened by the news about the passing of Prof. Hannah Engelberg-Kulka. Beyond her great contributions to science, to me as a student & many others at the Hebrew University, she was a great source of kindness, mentorship & relentless encouragement. RIP www.haaretz.co.il/magazine/obi...

haaretz.co.il

החוקרת שגילתה למה חיידקים מתאבדים מתה בגיל 92

הארץ

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ophirklein.bsky.social @ophirklein.bsky.social · 26/01/2025

Excited that our new lab website is starting to come together - thanks to the team, particularly Pauline Marangoni and Zhulin Dixon, for assembling this, and stay tuned for additional updates ophirkleinlab.org

ophirkleinlab.org

Home - Klein Lab

We are interested in understanding how organs form in the embryo and how they renew and regenerate in the adult. We research how development and regeneration

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 24/01/2025

Kind of fun to see the Cell chose our 2022 paper on Mouse Synthetic Embryo Models among highlighted landmark studies they published in the last decade (Cell line 2014-2024).

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 04/01/2025

Super nice work from the Naomi Morris group. The aspect of "co-development" elucidated by showing reciprocal interactions between somites & neural tube (via comparing somite only gastruloids vs. those that also have a neural tube) is a unique demonstration of the power of developmental models.

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 24/12/2024

A true masterpiece .. from chick development , to careful dissection of progenitor populations identity , to signaling needed to induce them to recapitulate notochord in human pscs . (Great way to open my Christmas family retreat on the couch). www.nature.com/articles/s41...

nature.com

Timely TGFβ signalling inhibition induces notochord - Nature

Through analysis of developing chick embryos and in vitro differentiation of embryonic stem cells, a study develops a method to generate a model of the human trunk with a notochord.

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 18/12/2024

Dear friends: While trying to make tripple knockin NUCLEAR fluorescent reporter lines, we've great signals with H2B-EGFP & H2B-tdTomato. But we r struggling with H2B-tagBFP regardless of the locus targeted. Anyone has a suggestion for a different H2B flourescent tag to combine with GFP & tdTomato?

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Alfonso Martinez Arias @amartinezarias.bsky.social · 17/12/2024

We've wondered for a while why #gastruloids are so sensitive to initial cell numbers. Here www.biorxiv.org/content/10.1... led by U, Fiuza, we explore this & observe effects of a number of variables on final structure and think what this tells us @ embryogenesis #IInNumbersWeTrust #NotInTheGenes

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 17/12/2024

Somebody sent me this from Paris. Since it is not me in the photo, i guess i may have a clone or twin brother working there.

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Johanna Joyce @johannajoyce.bsky.social · 14/12/2024

#50ScientistsThatInspire 🧪 Valentina Greco, a developmental biologist, explores the mechanisms governing an organism’s cellular communication.. "I hope that one day, our #diverse genders, races, countries of origin, sexual orientations, etc. will be welcomed in any field we choose to enter" 🧵

cell.com

Developmental and stem cell biologist Valentina Greco on building inclusivity by embracing difficult conversations and different perspectives

Advice on cultivating a healthy lab environment by valuing the people as much as the science and more from Dr. Greco.

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Didier Mazel @amazeld.bsky.social · 08/12/2024

We are opening a call for applications 2025 – Creation of new junior research groups at the Institut Pasteur in Paris @pasteur.fr all details on our web site : research.pasteur.fr/en/call/call...

research.pasteur.fr

Call for applications 2025 – Creation of new research groups at the Institut Pasteur | Research - Institut Pasteur

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 03/12/2024

When you officially buy Shawarma sandwich holders for the lab TC room, because it is the best way to make aggregates settle in a flask! Welcome to the middle east!

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