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Sachin Kotak

@spindlebehavior.bsky.social

89 followers 117 following 17 posts

Cell Biologist interested in fundamental cell division processes working @iiscbangalore

Posts Replies Media

Sachin Kotak @spindlebehavior.bsky.social · 15/09/2026

Can light build centrosome-like activity? 💡🔬 Yes! We introduce LISA (Light-Induced Spindle Assembly), now in @emboreports.org. By clustering Aurora A with optogenetics, we build centrosome-like activity that nucleates microtubules and rescues spindle defects after centrosome loss. shorturl.at/9h3VQ

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sveta-lab @svetac.bsky.social · 06/12/2025

Proud of two covers from India this year in JCB....both so beautiful, @rpadinjat.bsky.social and @spindlebehavior.bsky.social

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Sachin Kotak @spindlebehavior.bsky.social · 04/12/2025

Happy to see our work on how Aurora A kinase orchestrates nuclear organization by regulating the material properties of spindle pole–localized NuMA at mitotic exit featured on the cover. Grateful to the students for creating this beautiful image!

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The EMBO Journal @embojournal.org · 19/09/2025

New Aurora A kinase role in maintaining proper nuclear shape organization at mitotic exit: NuMA inhibition causes its dynamic-to-solid material-state transition, leading to bending of segregated mitotic chromosomes Sachin Kotak @spindlebehavior.bsky.social et al www.embopress.org/doi/full/10....

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Sachin Kotak @spindlebehavior.bsky.social · 13/09/2025

Happy to share our work in @embojournal 👉 shorturl.at/zXNyn For decades, we’ve known cells dismantle & rebuild the nuclear envelope in sync with spindle poles. But why does this coordination matter? And how do pole material properties ensure error-free division? Follow this thread to know more 👇

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Shweta Tyagi @shwetatyagi.bsky.social · 09/07/2025

It’s happening on the 15th!! #centrosome, #microtubules, #centromere, #mitosis, #cellbiology @kaustuvsanyal.bsky.social @viji-draviam.bsky.social @spindlebehavior.bsky.social

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Reposted by Sachin Kotak

Rockefeller University Press @rupress.org · 07/07/2025

The cover of @jcb.org's July issue (rupress.org/jcb/issue/22...) shows a confocal timelapse imaging of #Celegans one-cell embryo expressing fluorescently labeled plasma membrane, microtubules, chromosomes, and ZEN-4, a plus-end directed kinesin motor protein (Adhikary et al. doi.org/10.1083/jcb....)

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