Abstract. Amino acid-based phylogenetics usually relies on first clustering and aligning orthologous proteins. This approach is powerful but computationall

CLIMB is a cloud computing infrastructure for microbial bioinformatics — notebook servers, shared storage and reproducible workflows for genomics, metagenomics and pathogen surveillance researchers ac...

This year I went on two puffin watching experiences, and it is about time I reflect on this with a listicle / ranking. All on islands with decreasing populations of people and increasing populations o...

Agentic coding models such as codex and claude code are really useful for software engineering tasks. We sadly (and unsurprisingly) seem to be exiting the era of highly subsidised costs to get us hook...

The decision for the one-off vaccine programme follows the unprecedented outbreak in Kent this year.

This is a brief update to the previous menB analysis we’d posted here. UKHSA have released a technical briefing and further data which includes four further isolates from the outbreak, and a high qual...

A snakelike pipeline combining ggCaller and Panaroo. - samhorsfield96/ggCallaroo

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We’ve done a quick analysis on the meningitis outbreak genome to try and answer whether there is anything obviously genetically unusual about the publicly available outbreak strain. We aimed for three...

Previous posts on menB: First thoughts and summary Working hypothesis for outbreak UKHSA have sequenced one of the isolates from the outbreak, which is on PubMLST (190637). This is excellent and UKHSA...

Posted some thoughts on the menB outbreak yesterday. Now nine more cases, total at 27. A few more thoughts today, also after discussing with some others. A local factor seems necessary. I think pathog...

A cluster of meningitis cases is currently dominating the UK news. At least five of the cases have been confirmed as serotype B (menB), from what I can tell the others have not yet been analysed. My P...

Interactive exploration of large phylogenetic trees

Latest AlphaFold Database update adds high-value datasets for microbial and viral proteins, generated by specialist communities

We’re on a journey to advance and democratize artificial intelligence through open source and open science.

Do you want to lead groundbreaking research in computational biology? Join us at EMBL-EBI! EMBL's European Bioinformatics Institute (EMBL-EBI) is seeking talented and highly-motivated scientists to jo...

Mostly for personal reference for next year, here were my xmas dinner notes. I forgot about stuffing, and didn’t make yorkshire puddings properly because our main oven is broken (we have a convection ...

Dr Anders Bergström, School of Biological Sciences, University of East Anglia Professor Cock van Oosterhout, School of Environmental Sciences, University of East Anglia Dr Selina Brace…