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Peter Andersen

@germline.bsky.social
3.1K followers 866 following 159 posts

Germline genome regulation & genetic conflicts piRNAs | paralogs | epigenetics | transposons | flies Group leader, Aarhus University, Denmark (mbg.au.dk/pan) YOLO but germ cells are immortal and I wanna know how they do that.

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Reposted by Peter Andersen
Pravrutha Raman @pravrutharaman.bsky.social · 08/10/2026
Now that we have moved coasts, I am thrilled to share that the ChromEvo (Raman) lab is officially open at UMass Boston 🎉 We ask how CHROMatin EVOlution leads to functional innovation and we are hiring at multiple levels. Read on and share with folks who maybe interested chromevoramanlab.github.io
The logo with a phylogenetic tree, a budding yeast, a fly and a nucleosome that has Raman lab Chrom Evo written in the middle
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Peter Andersen @germline.bsky.social · 17h
Wow. Looking forward to reading this. Congrats!
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Antoine Molaro @antoinemolaro.bsky.social · 08/10/2026
Hello World ! Its pre-print time ! Awesome collaboration led by Michel Cohen-Tannoudji (not on Bsky) and the one and only @deborahbourchis.bsky.social. #BFF We solved the molecular mechanism underlying a mysterious hybrid incompatibility in mice: the DDK syndrome. 🧵🍿 www.biorxiv.org/content/10.6...
biorxiv.org
Transposable Element insertions Repurpose Immune Endonucleases as Drivers of Reproductive Isolation in Mice
The emergence of reproductive barriers between closely related populations is a fundamental step in speciation, yet the underlying genetic mechanisms remain poorly understood in mammals. Here we resol...
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Plaschka lab @plaschkalab.bsky.social · 08/10/2026
After excising an intron, the spliceosome gets trapped on the branched intron-lariat RNA. How are such dead-end spliceosomes terminated? Our latest paper led by @vytaute.bsky.social investigates the mechanism of spliceosome termination www.nature.com/articles/s41... (1/6)
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Maëlle Bellec @bellecmaelle.bsky.social · 07/10/2026
DNA → RNA → protein. From single mRNAs to an entire developing vertebrate embryo, we can now watch this last step unfold in real time. Our paper is out today! 🐟🔬 www.science.org/doi/10.1126/...
science.org
Real-time single-molecule imaging in zebrafish embryos uncovers noncanonical translation
Precise spatiotemporal control of protein synthesis is essential during embryogenesis, yet directly measuring translation kinetics in vivo remains challenging in vertebrates. In particular, it remains...
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ching-hochang.bsky.social @ching-hochang.bsky.social · 08/10/2026
Research is full of uncertainty, but every once in a while, nature works out exactly as you hypothesized. In 2019, while finishing my PhD, I pitched a bold idea in an email to @harmitmalik.bsky.social (below). Seven years later, it feels surreal to see that hypothesis become empirical reality. 🧵👇
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 08/10/2026
I'm not going to lie, this review puts the various challenges driving multicellularity very elegantly. For anyone excited about this field, this review is a must read. And damn this video is very very nice ! Congrats Will, Kai and Ozan.
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Alex de Mendoza @alexdemendoza.bsky.social · 06/10/2026
It's live! The next @embo.org #EvoChromo meeting will take place next year October in St Feliu de Guíxols (Spain), check it out here: meetings.embo.org/event/27-chr.... It's been great to co-organise with @dodonova-sveta.bsky.social @kellervalsecchi.bsky.social @cedricfeschotte.bsky.social & Nick I.
meetings.embo.org
Chromatin evolution from molecules to genomes
Technological advances over the past decade have enabled genome-wide mapping of chromatin organization across diverse organisms at unprecedented resolution. These studies have uncovered both conserve…
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Thibaut Brunet @thibautbrunet.bsky.social · 05/10/2026
One reason (among many) to study protists: as a toolbox, nature is unbeatable
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worm @rfksbrainworm.bsky.social · 02/10/2026
If you ever wondered why visible light is those particular wavelengths, it's because life evolved to see in the narrow range where water is transparent
Diagram of absorption of emf by water. There's a gap right that dips in the 500 nm range
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Magnus Kjærgaard @proteinmagnus.bsky.social · 30/09/2026
How does the extreme thermostability of de novo designed proteins arise? We aimed to answer this question by combined chemical and thermal denaturation of de novo designed minibinders in a paper out now in Protein Science (@proteinsociety.bsky.social): dx.doi.org/10.1002/pro....
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Maria Hondele @mariahondele.bsky.social · 29/09/2026
Nuclear speckles are “hot”, but how do they actually sequester mRNPs? We find that stalled mRNPs are retained in nuclear speckles by a combinatorial RNA-binding protein network. www.biorxiv.org/content/10.6...
biorxiv.org
A combinatorial pre-mRNP retention factor network couples nuclear speckle architecture to splicing quality control
Cells must prevent incompletely spliced transcripts from entering the cytoplasm, yet how splicing status is recognized and converted into selective nuclear retention remains unclear. Here, we identify...
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William Garland @willgarland.bsky.social · 29/09/2026
New from the lab! We uncover how the cap-binding complex promotes first-intron splicing: ZC3H18 recruits splicing factors while competing with the RNA-decay machinery, linking two alternative fates for newly made RNA. doi.org/10.1016/j.mo...
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Evgeny Kvon @evgenykvon.bsky.social · 29/09/2026
This is a really cool finding, congrats! It also reminds me of a recent paper from John Lis's lab showing that LTR promoter transcription in the NMU enhancer attenuates its activity: pubmed.ncbi.nlm.nih.gov/42468524/. So it appears to be a broader mechanism?
pubmed.ncbi.nlm.nih.gov
Checking your browser - reCAPTCHA
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Maxim Greenberg @maxvcg.bsky.social · 29/09/2026
Two more days to submit your abstract!!
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Nature Reviews Genetics @natrevgenet.nature.com · 29/09/2026
FYI: New online! The mechanistic and evolutionary diversity of programmed DNA elimination
dlvr.it
The mechanistic and evolutionary diversity of programmed DNA elimination
Nature Reviews Genetics, Published online: 08 September 2026; doi:10.1038/s41576-026-01004-7Programmed DNA elimination is a developmentally regulated process in which specific DNA sequences are reproducibly removed from particular cell lineages. Here, the authors review the mechanistic diversity and evolutionary dynamics of DNA elimination, spanning chromosome breakage, whole-chromosome elimination and whole-genome elimination.
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bioRxiv Genomics @biorxiv-genomic.bsky.social · 20/09/2026
Updated Transposable Element Libraries for Drosophila melanogaster in Dfam 4.0 www.biorxiv.org/content/10.64898/20…
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Mark A. Hanson @hansonmark.bsky.social · 26/09/2026
I'm surprised a community of publishing writers can blame AI for the problems of peer review when those same writers cite our study, "the strain on scientific publishing", which characterizes how this problem existed before AI. bit.ly/StrainQSS It's the incentives structure, not the AI. 1/n
scholarlykitchen.sspnet.org
Ask the Chefs: Peer Review Capacity — Uncomfortable Truths and Overlooked Conversations - The Scholarly Kitchen
For Peer Review Week 2026, we asked the Chefs two questions: What is one uncomfortable truth about peer review that the scholarly publishing community doesn’t talk about enough? And, beyond recruiting...
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Leah Houri-Zeevi @leahhouri.bsky.social · 25/09/2026
🩸🩸🩸TODAY WE SHARE TWO MAJOR DISCOVERIES🩸🩸🩸 1. We peered into genomes and brains of the rare mosquitoes that QUIT feeding on blood and found what biting is built from 2. Humans got rid of isoleucine in their blood, malaria suffers from it, and mosquito proteomes budget for it THREADS>
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Peter Andersen @germline.bsky.social · 25/09/2026
Transposons are going wild man This banger also just dropped: bsky.app/profile/maya...
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KamilSJaron.bsky.social @kamilsjaron.bsky.social · 18/09/2026
I am so excited to see this preprint out. I started working on springtails with @laurarossevo.bsky.social in 2019, but this pinnacle of our efforts manifested only with heroric leadership of Sam Ebdon! So, what's the deal? 👇
Globular springtail Allacma fusca. Female, one of the samples in the linked preprint.
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Cedric Feschotte @cedricfeschotte.bsky.social · 24/09/2026
Thrilled to see this published today! Truly special because we made the initial discovery >15 yrs ago! We found two copies of a human gene called BC200 embedded in a human poxvirus. BC200 blurs the line between gene & transposon—both functional & mutagenic! www.science.org/doi/10.1126/... 🧵1/n
science.org
Escape of the BC200 gene to a human poxvirus reveals its persistent transposition in primates
Transposable elements mobilize within and occasionally between genomes, including from host to virus. We identified two insertions of the human BC200 noncoding RNA gene in the poxvirus molluscum conta...
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Peter Andersen @germline.bsky.social · 24/09/2026
Incredibly cool new transposon biology!
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Randall Munroe @xkcd.com · 22/09/2026
Tyrannosaurus xkcd.com/3300/
Comic. [Person with long hair pointing to diagram with Tyrannosaurus Rex standing next to a person.] PERSON: We now believe the primary prey of Tyrannosaurus Rex was these humans who kept standing next to it for scale.
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Peter Andersen @germline.bsky.social · 08/09/2026
We are recruiting a PhD student 🥼🙋 Topic: how germ cells bend gene expression dogmas Fly genetics + proteomics + genomics. Fully funded. Aarhus University 🇩🇰 info on the project and how to apply👇 mbg.au.dk/en/peter-and... I'd really appreciate it if you'd help spread the word. Thanks
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Ben Parker @ben-parker.bsky.social · 21/09/2026
Excited that our new paper with @henrylabsymbio.bsky.social and Kerry Oliver is out @pnas.org! We show that mobile genetic elements can spread adaptive host-benefiting traits across heritable insect symbionts on eco-evolutionary timescales.🧵 www.pnas.org/doi/10.1073/...
pnas.org
Phenotypic divergence is driven by mobile genetic elements in a heritable insect symbiont | PNAS
Heritable microbes profoundly influence insect biology, yet the traits they confer often evolve rapidly and differ among closely related symbiont s...
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Peter Andersen @germline.bsky.social · 20/09/2026
Looks really interesting. Congrats to you and all involved, Maria!
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Maria Hondele @mariahondele.bsky.social · 18/09/2026
The heatwave is finally over - just in time for our “Frosty Foci” to finally come online! ❄️🦠 We found that E. coli builds a transient nucleolus-like ribosome biogenesis compartment during cold adaptation, when RNA (mis)folding makes ribosome biogenesis challenging.
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André Marques @amarques.bsky.social · 16/09/2026
Out today in Nature: sex without crossovers. Rhynchospora tenuis makes pollen, fertilises and sets seed, yet 0 crossovers in 10,997 pollen nuclei. Chromosome drive and ~87% seed abortion rebuild the mother's genotype, so the offspring are clones. doi.org/10.1038/s415...
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Lily Khadempour @khadlily.bsky.social · 15/09/2026
I'm happy to share my new paper "A new conceptual framework for host-microbe symbiosis" If you've seen me give a talk in the last 5 years, then you've seen me talk about this. It's been a journey. academic.oup.com/ismehm/artic... #MicroSky #MicrobiomeSky
academic.oup.com
A new conceptual framework for host-microbe symbiosis
Abstract. Host-microbe relationships are studied across biological disciplines, with unique but overlapping conceptual frameworks arising from each of them
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Peter Andersen @germline.bsky.social · 16/09/2026
Enjoy the meeting!
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Peter Andersen @germline.bsky.social · 16/09/2026
The early bird gets the worm.. s to worm school in time.
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Maxim Greenberg @maxvcg.bsky.social · 15/09/2026
Very happy to announce that @emboreports.org will be sponsoring a cash prize for the best poster at Ctrl+Epi+Edit ✒️🧬! Still time to register and submit an abstract (speaking slots still open also), but it's filling up, so act fast! Thanks for the support 🙏 ctrlepiedit.sciencesconf.org
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Magnus Kjærgaard @proteinmagnus.bsky.social · 13/09/2026
How does linear motifs drive dephosphorylation - and does it matter where and how strong the motifs are? These are the question Evi answers in her brand new pre-print: www.biorxiv.org/content/10.6...
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Tobias Warnecke @tobiaswarnecke.bsky.social · 11/09/2026
One of the coolest projects I've seen over the last few years. If you have a chance to invite @florianmayer.bsky.social for a talk, you definitely should! You'd be in for a treat.
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fly paper broadcast @fly-broadcast.bsky.social · 09/09/2026
Pathway to Independence - an interview with Maëlle Bellec #Drosophila
pubmed.ncbi.nlm.nih.gov
Pathway to Independence - an interview with Maëlle Bellec #Drosophila
PubMed link
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 11/09/2026
Very proud of the team, led by @baukjeje.bsky.social & @fmikus.bsky.social To all of you doing #Expansion #Microscopy #UExM Try Concanavalin A. Its cheap, easy to use & labels the #nuclear #Envelope @moorefound.bsky.social @embl.org @sciencesunige.bsky.social @erc.europa.eu @snsf.ch
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Anton Goloborodko @golobor.bsky.social · 10/09/2026
New preprint from our group (led solely by our student Vladimir Dmitriev): a valency-bounding correction (VBC) for coarse-grained MD. It lets you cap how many neighbours a particle can bind, without introducing explicit patches or fixed bond directions. arxiv.org/abs/2609.07842 1/
arxiv.org
Valency-bounding correction potential for coarse-grained molecular dynamics simulations
Many systems in soft and living matter bind through a limited number of bonds per particle: proteins associate via discrete surface patches, nucleic acids form one-to-one contacts, and the phase behav...
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Laura Ross @laurarossevo.bsky.social · 10/09/2026
My lab @ Edinburgh university is recruiting a postdoc to work on the weird and wonderful germline-specific chromosomes of flies. elxw.fa.em3.oraclecloud.com/hcmUI/Candid... collaboration with @germline.bsky.social and yukiko yamashita funded by @novonordisk.bsky.social please repost!
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Robert Kofler @rokofler.bsky.social · 10/09/2026
super proud - my very first review is online www.annualreviews.org/content/jour... many thanks to @signor-molevol.bsky.social @rpianezza.bsky.social @almoroscarpa.bsky.social for the fun collaboration
annualreviews.org
The History of Transposable Element Invasions in Drosophila melanogaster
As a fundamental biological principle, genomic information is typically transmitted vertically from parent to offspring. Occasionally, however, genetic material is transferred horizontally between spe...
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Antoine Molaro @antoinemolaro.bsky.social · 09/09/2026
Hello World ! Reminder about our open postdoc position 🧪🧬 Reviewing applications until October - get in touch to know more about what's hot in the lab these days ! Application details in the post below 👇👇 #EvoEpi #MolaroLab #watwat #ERC
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Laura Ross @laurarossevo.bsky.social · 08/09/2026
Ever wondered why diverse organism shrink their genome in specific cells? We try to make sense of these curious cases of programmed DNA elimination in a review that came out today @naturerevgenet.bsky.social trebuchet.public.springernature.app/get_content/... @sandraduharcourt.bsky.social
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Virginia Busetto @virginiabusetto.bsky.social · 08/09/2026
Very excited to share our new preprint: “A pseudohelicase-centered complex couples assembly-dependent RNA cleavage to poly(UG)ylation”! 🎉 Want to know more? 🧵👇 www.biorxiv.org/content/10.6...
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sandraduharcourt.bsky.social @sandraduharcourt.bsky.social · 08/09/2026
Very happy to see our Nature Reviews Genetics article on programmed DNA elimination across eukaryotes out! A fantastic collective effort with an amazing group of colleagues, born from inspiring discussions at the Fondation des Treilles. rdcu.be/tmvKgsPZNhBa @laurarossevo.bsky.social
rdcu.be
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Peter Andersen @germline.bsky.social · 08/09/2026
We are recruiting a PhD student 🥼🙋 Topic: how germ cells bend gene expression dogmas Fly genetics + proteomics + genomics. Fully funded. Aarhus University 🇩🇰 info on the project and how to apply👇 mbg.au.dk/en/peter-and... I'd really appreciate it if you'd help spread the word. Thanks
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Madalena M. Reimão Pinto @madalenamrp.bsky.social · 07/09/2026
Applications for the IMPRS Bio-MAP PhD program now open! 🎉 dipp.cmcb.tu-dresden.de/ausschreibun...
dipp.cmcb.tu-dresden.de
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Peter Andersen @germline.bsky.social · 07/09/2026
Thanks for pointing this out. It's a column layout issue. My vanity with making preprints pretty is a failsafe supply of mistakes like this. Will be fixed in v2 soon-to-come...
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Peter Andersen @germline.bsky.social · 07/09/2026
Thanks, Geoff! The exceptional TEs were actually our starting point, exactly thinking we could use TE promoter divergence to identify which TFs different TEs use. That turned out to be a difficult and underpowered path (at least for us). I still like the idea and would love to figure a solution.
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Torben Heick Jensen @heick.bsky.social · 05/09/2026
2. call for a postdoc position with Torben Heick Jensen, Aarhus University, Denmark. Get in touch for further information or simply apply using this link: www.au.dk/om/stillinge...
au.dk
Postdoc position in Nuclear RNA Biology - Ledig stilling på Aarhus Universitet
Ledig stilling ved Institut for Molekylærbiologi og Genetik - RNA-biologi og -innovation, Aarhus Universitet
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Anton Goloborodko @golobor.bsky.social · 03/09/2026
1/ out in @science.org! We found a new asymmetry in large-scale chromosome structure: sister chromatids are shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! A close collaboration w/ @gerlichlab.bsky.social , led by @flaviacorsi.bsky.social www.science.org/doi/10.1126/...
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