bioRxiv Genomics @biorxiv-genomic.bsky.social · 56mMulti-omic long-read sequencing reveals nucleosome control of transcriptional fidelity at the isoform level www.biorxiv.org/content/10.64898/20… 010
bioRxiv Genomics @biorxiv-genomic.bsky.social · 57mSystematic mapping of enhancers, silencers, and topological elements with prime editing deletion screens www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 1hRandom mtDNA mutagenesis maps genotype-phenotype associations across metabolic contexts and lineages www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 1hCentromeric islands constrain CENP-A domain size and position www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 2hHigh-throughput identification of chromatin-opening transcription factors www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 2hThe adaptive architecture of tRNA dependencies across physiological tumor environments www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 2hFine-tuning genomic models on rare splicing events identifies a novel biomarker of TDP-43 pathology www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 2hCerberus: bidirectional state space blocks improve accuracy and efficiency of regulatory sequence models www.biorxiv.org/content/10.64898/20… 011
bioRxiv Genomics @biorxiv-genomic.bsky.social · 3hSTEER-seq: a recombinase based platform for pooled multimodal single-cell perturbation screening www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 4hSingle-nucleus multi-omics reveals reversible molecular signatures in skeletal muscle of patients with heart failure with preserved ejection fraction www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 13hSeascape genomics reveals shared spatial genetic structure in three co-occurring sea snakes www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 14hProtein response to deleterious episodes of GC-biased gene conversion in mammals of different Ne www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 08/10/2026The impact of sex and ancestry on the molecular landscape of pancreatic adenocarcinoma www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 08/10/2026Sex-dependent DNA methylation in amyotrophic lateral sclerosis www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 08/10/2026Heterochromatin protein 1α acts as an essential stabilizer of chromatin packing domains www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 08/10/2026A gene-centric analysis of copy number variation reveals tumour suppressor modulation of cancer risk and novel associations with common diseases www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 07/10/2026Genome-wide structural variants uncover strain-specific genes and evolutionary genomic determinants of a fungal maize pathogen www.biorxiv.org/content/10.64898/20… 022
bioRxiv Genomics @biorxiv-genomic.bsky.social · 07/10/2026Chromosome-scale genome assembly of the North American invasive Asteraceae, Tanacetum vulgare (common tansy) www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 07/10/2026Synergistic effects of hypergravity and immune challenge on the zebrafish larval transcriptome www.biorxiv.org/content/10.64898/20… 010
bioRxiv Genomics @biorxiv-genomic.bsky.social · 07/10/2026Analysis of Naturally Arising Simple Deletions in Single Human Colon Crypts with Age www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 06/10/2026Gene transcriptional profiling to assess Chinook salmon osmoregulatory resilience to salinity challenges www.biorxiv.org/content/10.64898/20… 010
bioRxiv Genomics @biorxiv-genomic.bsky.social · 06/10/2026Coordinated microRNA-mRNA regulatory remodelling across the compressed maturation of the African killifish (Nothobranchius furzeri) www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 06/10/2026A map of RBP-miRNA regulatory connections for deciphering the mechanisms of transcriptome remodeling in cancer www.biorxiv.org/content/10.64898/20… 010
bioRxiv Genomics @biorxiv-genomic.bsky.social · 06/10/2026MERFISH-based pooled genetic screening reveals cell non-autonomous phenotypes in intact tissue www.biorxiv.org/content/10.64898/20… 020
bioRxiv Genomics @biorxiv-genomic.bsky.social · 06/10/2026A near-ubiquitous plasmid characterises Second Pandemic Yersinia pestis www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 06/10/2026Conservation of gene co-expression networks and neuropsychiatric-neurological disease gene programs between mouse and human frontal cortex at single-cell resolution www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 06/10/2026Haplotype-phased, chromosome-level, annotated genome assembly of the soybean rust pathogen Phakopsora pachyrhizi www.biorxiv.org/content/10.64898/20… 010
bioRxiv Genomics @biorxiv-genomic.bsky.social · 06/10/2026Hidden but Expanding Sampling Bias Distorts Prokaryotic Genome Collections www.biorxiv.org/content/10.64898/20… 021
bioRxiv Genomics @biorxiv-genomic.bsky.social · 05/10/2026Defining the spectrum of cellular protection against cadmium stress by Dsup expressed in yeast www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 05/10/2026Pangenome and transcriptome analyses reveal extensive diversity and breeding signatures in the oat GDSL-esterase/lipase gene family www.biorxiv.org/content/10.64898/20… 010
bioRxiv Genomics @biorxiv-genomic.bsky.social · 05/10/2026The mammalian genome is punctuated by regularly spaced nucleosome islands www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 05/10/2026Genetic exchange drives relatedness of large linear and circular extrachromosomal elements of archaea www.biorxiv.org/content/10.64898/20… 011
bioRxiv Genomics @biorxiv-genomic.bsky.social · 05/10/2026Distinct sequence grammars of nucleosomal and linker DNA shape mutational and methylation landscapes in cancer www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 05/10/2026Disease-associated mutations directionally modulate epigenetic age in iPSC-derived tissues www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 02/10/2026X-Y divergence of house fly (Musca domestica) proto-sex chromosomes follows distinct evolutionary trajectories despite residing in the same genome www.biorxiv.org/content/10.64898/20… 086
bioRxiv Genomics @biorxiv-genomic.bsky.social · 02/10/2026Method-dependent biases in cell type detection between single-cell and single-nucleus RNA sequencing in the photosymbiotic acoel Praesagittifera naikaiensis www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 02/10/2026Genome-wide mapping of endogenous topoisomerase cleavage complexes reveals TOP1 at the interface of DNA topological regulation and genome instability www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 02/10/2026Topoisomerase-mediated resolution of negative DNA supercoiling sustains human transcription and gene activation www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 02/10/2026Applying AlphaGenome Variant Impact for SNV Prioritization www.biorxiv.org/content/10.64898/20… 020
bioRxiv Genomics @biorxiv-genomic.bsky.social · 02/10/2026Genetic risk and inflammatory signaling converge on cell type-specific regulatory programs in type 1 diabetes www.biorxiv.org/content/10.64898/20… 020
bioRxiv Genomics @biorxiv-genomic.bsky.social · 01/10/2026Scalable saturation mutagenesis reveals gene regulatory architecture and rare variant effects www.biorxiv.org/content/10.64898/20… 041
bioRxiv Genomics @biorxiv-genomic.bsky.social · 01/10/2026The Genome In A Bottle HG002 assembly-based variant benchmark set enables comprehensive benchmarking of small and structural variants. www.biorxiv.org/content/10.64898/20… 032
bioRxiv Genomics @biorxiv-genomic.bsky.social · 01/10/2026Chromosome-level genome assembly of the Olympia oyster (Ostrea lurida), the only oyster species native to the West Coast of North America www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 01/10/2026Factors underlying creativity show distinct genetic architecture and genetic correlations with psychiatric disorders www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 01/10/2026Intelligence and the Big Five personality traits share a genetic and biological basis www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 01/10/2026Genomic structural variation in clownfish adaptive radiation www.biorxiv.org/content/10.64898/20… 021
bioRxiv Genomics @biorxiv-genomic.bsky.social · 01/10/2026Phylodynamic analysis reveals asymmetric and accelerating global spread of dengue virus www.biorxiv.org/content/10.64898/20… 011
bioRxiv Genomics @biorxiv-genomic.bsky.social · 01/10/2026Whole-genome characterization of Plasmodium falciparum population structure and drug resistance across Uganda and neighboring countries www.biorxiv.org/content/10.64898/20… 000
bioRxiv Genomics @biorxiv-genomic.bsky.social · 01/10/2026Rapid whole genome- and annotation-based multilocus sequence typing of the fungal pathogen Histoplasma capsulatum www.biorxiv.org/content/10.64898/20… 011
bioRxiv Genomics @biorxiv-genomic.bsky.social · 30/09/2026Evo 2 as a classification machine: evidence from in-context learning and mechanistic interpretability www.biorxiv.org/content/10.64898/20… 012
