This randomized clinical trial estimates the effect size of connectivity- vs scalp-based targeting of accelerated transcranial magnetic stimulation for treatment-resistant depression.

Tumour network mapping of diffuse midline glioma (DMG) defines a conserved and prognostically important brain network in children with DMG, consistent with the hypothesis that DMGs exploit otherw...

Combining a computational framework and optogenetic and chemogenetic manipulations within and downstream of the cortico-basal ganglia circuit identifies the specific cortico-basal ganglia synapse...

After a January paper questioned the validity of an approach called lesion network mapping, its users are pressure testing their results.

Bahners et al. identify a brain network linked to optimal therapeutic outcomes in patients with Parkinson’s disease receiving deep brain stimulation. This

The absence of visual mental imagery, called aphantasia, occurs congenitally in up to 3% of the general population, but the brain regions responsible …

Explore cutting-edge advances in brain medicine with this interdisciplinary course designed to equip clinicians with integrated tools for assessing and managing complex brain disorders, featuring expe...

Two new studies add to a remarkable body of evidence for benefit

The lesion network mapping method, used to identify disease-specific brain networks for clinical stimulation, produces a nearly identical network map for any given condition, according to a new study.

The lesion network mapping method links diverse brain lesions to similar functional brain networks, reflecting general brain organization rather than disorder-specific circuits.

Dystonia is one of the most prevalent movement disorders, but its neural substrates have remained enigmatic despite decades of research. Brain lesions leading to dystonia offer unique causal inference...

Depression is a common and debilitating psychiatric disorder that is associated with substantial morbidity and mortality. For nearly 40 years, scientists have attempted to localize depression in the b...

NextBrain is an open source, probabilistic atlas of the entire human brain, assembled using artificial-intelligence-enabled registration and segmentation methods to reconstruct the multimodal serial h...

Today, BD², or Breakthrough Discoveries for thriving with Bipolar Disorder, announced its third round of Discovery Research grants, totaling nearly $18 million – expanding a comprehensive global effor...

An internationally recognized scientist, her work has transformed our understanding of the brain networks that play a central role in many mental health disorders, including obsessive compulsive disor...