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Stimulating Brains

@stimulatingbrains.org
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A podcast & talk series about brain stimulation and stimulating brains. Home at the @netstim.org

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Lead-DBS @lead-dbs.org · 19/09/2026
New publication using Lead-DBS: In this article by Hanafi et al., the authors tested gait-adaptation kinematics, EEG, and FDG‑PET in Parkinson's patients during virtual obstacle avoidance with active versus paused STN‑DBS and... Check out the paper here 👇👇 doi.org/10.1016/j.brs.2026.103207
Title card for publication: Subthalamic DBS Engages Right-lateralized Frontal Control to Improve Gait Adaptation in Parkinson’s Disease
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 12/09/2026
New publication using Lead-DBS: In this article by Kist et al., patients with OCD treated with subthalamic deep brain stimulation performed visual detection and confidence judgments with EEG, showing intact detection but poor... Check out the paper here 👇👇 doi.org/10.1038/s41398-026-04423-6
Title card for publication: Assessing the effect of subthalamic stimulation on metaperception in obsessive-compulsive disorder
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 11/09/2026
New publication using Lead-DBS: In this article by Singh et al., a three‑center retrospective study of 22 patients with drug‑resistant insular epilepsy treated with responsive neurostimulation or chronic subthreshold stimulation repor... Check out the paper here 👇👇 doi.org/10.1002/epi.70479
Title card for publication: Invasive network neuromodulation for insular epilepsy: A three-center retrospective study
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 10/09/2026
New publication using Lead-DBS: In this article by Huang et al., the authors mapped pain-related networks using rapid stereo-EEG to enable personalized multinodal stimulation for refractory facial pain. Check out the paper here 👇👇 doi.org/10.1016/j.brs.2026.103176
Title card for publication: Rapid stereo-EEG network mapping enables personalized multinodal stimulation for refractory facial pain
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 09/09/2026
New publication using Lead-DBS: In this article by Meyer et al., the authors tested in 19 Parkinson’s patients whether subthalamic deep brain stimulation modulates automatic response inhibition and showed that stimulation spe... Check out the paper here 👇👇 doi.org/10.1093/braincomms/fcag325
Title card for publication: Hyperdirect projections from the supplementary motor area mediate subthalamic stimulation effects on movement initiation and inhibition in Parkinson’s disease
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 08/09/2026
New publication using Lead-DBS: In this article by Dary et al., they tested whether circadian modulation of aperiodic and oscillatory intracranial EEG could serve as a biomarker of seizure burden in 19 patients with Lennox–Gastaut syn... Check out the paper here 👇👇 doi.org/10.1002/epi.70457
Title card for publication: Circadian modulation of aperiodic background and oscillatory activity as a biomarker of seizure burden in Lennox-Gastaut syndrome
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 07/09/2026
New publication using Lead-DBS: In this article by Liu et al., the authors tested direct substantia nigra DBS in Parkinson's disease at 10, 30, and 130 Hz, observed a frequency-dependent acute motor and stride-length benefit w... Check out the paper here 👇👇 doi.org/10.1016/j.brs.2026.103186
Title card for publication: Direct Substantia Nigra Deep Brain Stimulation in Parkinson’s Disease: Efficacy, Safety, and the Frequency-Response Relationship
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 06/09/2026
New publication using Lead-DBS: In this article by Goede et al., the authors used DBS network mapping across multiple patient cohorts to show that rest tremor and action tremor map to distinct subnetworks within the primary... Check out the paper here 👇👇 doi.org/10.1016/j.celrep.2026.117404
Title card for publication: Action and rest tremor map to distinct networks within the primary motor cortex
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Stimulating Brains @stimulatingbrains.org · 25/08/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/81-theodore-s…
Quote card for Stimulating Brains #81: Theodore Schwartz - Gray Matters: brain surgery from the inside, the history and the future of neurosurgery. Quote from Theodore Schwartz: Every heartbeat, every respiration, the brain moves. And so it's like operating on a beating heart, you know, you're operating on a beating brain.
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 24/08/2026
Classic publication using Lead-DBS: In this article by Wilkins et al., the authors tested whether swing time variability is a behavioral marker of cortical cholinergic integrity in Parkinson's disease and... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Gait variability is linked to the atrophy of the Nucleus Basalis of Meynert and is resistant to STN DBS in Parkinson's disease
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 23/08/2026
New publication using Lead-DBS: In this article by Las Vegas Sands Corp. et al., the authors report a lawsuit filed by Las Vegas Sands Corp. against unknown registrants of multiple domain names, including www.wn0000.com, www.wn... Check out the paper here 👇👇 doi.org/10.1089/glre.2016.201011
Title card for publication: LAS VEGAS SANDS CORP., a Nevada corporation, Plaintiff, v. UKNOWN REGISTRANTS OF www.wn0000.com, www.wn1111.com, www.wn2222.com, www.wn3333.com, www.wn4444.com, www.wn5555.com, www.wn6666.com, www.wn7777.com, www.wn8888.com, www.wn9999.com, www.112211.com, www.4456888.com, www.4489888.com, www.001148.com, and www.2289888.com, Defendants.
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Stimulating Brains @stimulatingbrains.org · 21/08/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/78-keith-mull…
Quote card for Stimulating Brains #78: Keith Mullett — Medtronic, pain, and the prehistory of modern DBS. Quote from Keith Mullett: The whole concept of stimulation as an alternative to drug therapy was to avoid the overuse of opioids.
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Lead-DBS @lead-dbs.org · 21/08/2026
Classic publication using Lead-DBS: In this article by Mosley et al., the authors tested whether individual variability in initiation, inhibition and strategy use in Parkinson's patients receiving subthala... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Subthalamic deep brain stimulation identifies frontal networks supporting initiation, inhibition and strategy use in Parkinson's disease
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 20/08/2026
Classic publication using Lead-DBS: In this article by Suresh et al., the authors tested nocturnal centromedian thalamic nucleus DBS in a patient with drug‑resistant idiopathic generalized epilepsy u... Check out the paper here 👇👇 www.frontiersin.org/articles/10.338…
Title card for publication: Case report: Nocturnal low-frequency stimulation of the centromedian thalamic nucleus improves sleep quality and seizure control
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 19/08/2026
Classic publication using Lead-DBS: In this article by Davidson et al., the authors tested deep brain stimulation of the nucleus accumbens as a treatment for severe alcohol use disorder in a phase I pilot trial. Check out the paper here 👇👇 www.nature.com/articles/s41380-022-…
Title card for publication: Deep brain stimulation of the nucleus accumbens in the treatment of severe alcohol use disorder: a phase I pilot trial
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Stimulating Brains @stimulatingbrains.org · 18/08/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/79-karl-frist…
Quote card for Stimulating Brains #79: Karl Friston — The Origins of SPM and the Making of Modern Human Brain Mapping. Quote from Karl Friston: So the very first implementation of SPM was actually writing down the statistical equations in an Excel spreadsheet, where each cell in the Excel spreadsheet was corresponding to a voxel.
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 18/08/2026
Classic publication using Lead-DBS: In this article by Coblentz et al., the authors reported outcomes of GPi deep brain stimulation in 11 pediatric patients with refractory dystonia and used MR... Check out the paper here 👇👇 thejns.org/view/journals/j-neurosur…
Title card for publication: Mapping efficacious deep brain stimulation for pediatric dystonia
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 17/08/2026
Classic publication using Lead-DBS: In this article by Wong et al., the authors report a case of GPi deep brain stimulation–induced ‘‘dystypia’’ (impaired typing), document improvement with the device... Check out the paper here 👇👇 www.frontiersin.org/articles/10.338…
Title card for publication: Case Report: Globus Pallidus Internus (GPi) Deep Brain Stimulation Induced Keyboard Typing Dysfunction
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Stimulating Brains @stimulatingbrains.org · 16/08/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/71-harold-sac…
Quote card for Stimulating Brains #71: Harold Sackeim – The founding editor of Brain Stimulation and a founding figure in modern electroconvulsive therapy. Quote from Harold Sackeim: Helplessness is the default state. We're born helpless. What we do is learn control or what I call resilience.
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Lead-DBS @lead-dbs.org · 16/08/2026
Classic publication using Lead-DBS: In this article by Bouwens Van Der Vlis et al., the authors report clinical outcomes in eight refractory OCD patients treated with ventral capsule/ventral striatum DBS a... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Ventral Capsule/Ventral Striatum Stimulation in Obsessive-Compulsive Disorder: Toward a Unified Connectomic Target for Deep Brain Stimulation?
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Lead-DBS @lead-dbs.org · 15/08/2026
New publication using Lead-DBS: In this article by Bryant et al., the authors introduce subcortex_visualization, an open-source Python and R toolbox providing standardized, vector-based 2D visualizations of region-level subco... Check out the paper here 👇👇 doi.org/10.64898/2026.01.23.699785
Title card for publication: Subcortex visualization: A toolbox for custom data visualization in the subcortex and cerebellum
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Stimulating Brains @stimulatingbrains.org · 14/08/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/69-terrence-s…
Quote card for Stimulating Brains #69: Terence Sanger – Pushing Boundaries in Pediatric DBS: From Multi-Electrode Stimulation to Closed-Loop Strategies. Quote from Terence Sanger: DBS is like trying to fix a computer using a hairdryer. You know, you can warm it up, you can cool it down, but sometimes that's what it needs.
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 14/08/2026
New publication using Lead-DBS: In this article by Chen et al., they tested whether long‑latency reflex II (LLR II) is modulated by STN‑DBS parameters and dopaminergic medication in Parkinson's disease, finding higher LLR II with clin... Check out the paper here 👇👇 doi.org/10.1002/mds.70508
Title card for publication: Subthalamic Nucleus Deep Brain Stimulation Enhanced Long‐Latency Reflex
                    <scp>II</scp>
                    in Parkinson's Disease Through Rapid Subthalamic–Cortical Modulation
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 13/08/2026
Classic publication using Lead-DBS: In this article by Filip et al., the authors tested whether subthalamic nucleus deep brain stimulation normalizes resting-state functional MRI metrics in Parkinson’s dis... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Mixed anxiety-depressive disorder in Parkinson’s disease associated with worse resting state functional response to deep brain stimulation of subthalamic nucleus
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 12/08/2026
Classic publication using Lead-DBS: In this article by Hell et al., the authors recorded subthalamic nucleus LFPs in Parkinson’s patients during walking and rest with and without stimulation and showed gai... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Subthalamic oscillatory activity and connectivity during gait in Parkinson's disease
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 11/08/2026
Classic publication using Lead-DBS: In this article by Dembek et al., the authors tested five published DBS sweetspot-mapping methods in silico across eight scenarios and found highly variable identified s... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Sweetspot Mapping in Deep Brain Stimulation: Strengths and Limitations of Current Approaches
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Lead-DBS @lead-dbs.org · 10/08/2026
Classic publication using Lead-DBS: In this article by Ge et al., the authors prospectively tested deep brain stimulation of the nucleus accumbens with or without the anterior limb of the internal capsule in 20 treatm... Check out the paper here 👇👇 www.nature.com/articles/s41398-025-…
Title card for publication: Effects of deep brain stimulation of the nucleus accumbens and anterior limb of the internal capsule on heroin addiction: Over five years of long-term follow-up in a prospective open-label pilot study
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Lead-DBS @lead-dbs.org · 09/08/2026
Classic publication using Lead-DBS: In this article by Zhang et al., the authors showed that electrode reconstruction can assist postoperative contact selection in deep brain stimulation. Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Electrode Reconstruction Assists Postoperative Contact Selection in Deep Brain Stimulation
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Reposted by Stimulating Brains
Lead-DBS @lead-dbs.org · 08/08/2026
New publication using Lead-DBS: In this article by Unknown et al., they announce a ScienceDirect article in press in Assessing Writing. Check out the paper here 👇👇 doi.org/10.1016/s1075-2935(04)00016…
Title card for publication: Announcement (ScienceDirect Article in Press)
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Stimulating Brains @stimulatingbrains.org · 07/08/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/67-jonathan-d…
Quote card for Stimulating Brains #67: Jonathan Downar – TMS for depression: Towards a One-Day protocol. Quote from Jonathan Downar: It's possible that up to 50% of the cost of a TMS session right now is just people arguing over whether to pay the other half.
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Lead-DBS @lead-dbs.org · 07/08/2026
New publication using Lead-DBS: In this article by Luo et al., the authors identified brain circuits associated with gait impairment after stroke and with gait changes following subthalamic DBS for Parkinson's disease, and found lesio... Check out the paper here 👇👇 doi.org/10.1002/ana.78320
Title card for publication: A Human Gait Circuit Derived from Brain Lesions and Deep Brain Stimulation
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Lead-DBS @lead-dbs.org · 05/08/2026
Classic publication using Lead-DBS: In this article by Segura-Amil et al., the authors used patient-specific probabilistic tractography in 20 Parkinson's disease patients with bilateral STN DBS to build models link... Check out the paper here 👇👇 onlinelibrary.wiley.com/doi/10.1002…
Title card for publication: Programming of subthalamic nucleus deep brain stimulation with hyperdirect pathway and corticospinal tract‐guided parameter suggestions
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Stimulating Brains @stimulatingbrains.org · 04/08/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/72-john-rolst…
Quote card for Stimulating Brains #72: John Rolston — Closed-Loop Stimulation, Seizure Dynamics, and the New Frontiers of Epilepsy Treatment. Quote from John Rolston: There's gene therapy and cell therapy for epilepsy that are coming online. We're learning more about the genes that are involved in it and seeing things like post-mitotic mutations in the brain.
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Lead-DBS @lead-dbs.org · 04/08/2026
Classic publication using Lead-DBS: In this article by Ehlen et al., the authors tested effects of thalamic (VIM) deep brain stimulation in essential tremor patients on verbal fluency, finding DBS ON prolo... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Thalamic deep brain stimulation decelerates automatic lexical activation
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Stimulating Brains @stimulatingbrains.org · 03/08/2026
New on Stimulating Brains: @doriswang.bsky.social on adaptive DBS synchronized with the moment-by-moment rhythm of walking—and what it could mean for gait and falls in Parkinson’s disease. 🎧 stimulatingbrains.org/82-doris-wan... #DeepBrainStimulation #AdaptiveDBS #ParkinsonsDisease #Neurosurgery
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Lead-DBS @lead-dbs.org · 02/08/2026
Classic publication using Lead-DBS: In this article by Provenza et al., the authors used continuous ventral-striatum recordings from 12 people with treatment‑resistant OCD receiving DBS to show that pre‑stimulation th... Check out the paper here 👇👇 www.nature.com/articles/s41591-024-…
Title card for publication: Disruption of neural periodicity predicts clinical response after deep brain stimulation for obsessive-compulsive disorder
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Stimulating Brains @stimulatingbrains.org · 31/07/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/58-ali-rezai-…
Quote card for Stimulating Brains #58: Ali Rezai – Long lasting Effects of Focused Ultrasound for Addiction. Quote from Ali Rezai: I think the future of functional neurosurgery is exciting, but again, it's the convergence of imaging, technological innovations.
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Stimulating Brains @stimulatingbrains.org · 30/07/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/54-phil-starr…
Quote card for Stimulating Brains #54: Phil Starr – Using cortical signals to guide DBS, how lesions may produce brain signals and open collaborations in the field.. Quote from Phil Starr: I think for me, doing what I do best, which is human invasive brain reporting, has been the best thing I've ever done.
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Lead-DBS @lead-dbs.org · 30/07/2026
Classic publication using Lead-DBS: In this article by Zvarova et al., the authors developed and validated a multimodal neuroimaging‑informed model—combining active contact coordinates, electric fields, tract activations, and structur... Check out the paper here 👇👇 doi.org/10.1002/ana.78206
Title card for publication: Multimodal Image Guidance in Subthalamic Deep Brain Stimulation for Parkinson's Disease
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Stimulating Brains @stimulatingbrains.org · 29/07/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/68-todd-herri…
Quote card for Stimulating Brains #68: Todd Herrington – The Future of Neuromodulation: Insights from the ADAPT PD Trial and Beyond. Quote from Todd Herrington: In a single patient with Parkinson's disease, I think this was really a breakthrough of a feasibility trial, but also did show some really promising results.
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Lead-DBS @lead-dbs.org · 29/07/2026
New publication using Lead-DBS: In this review by Hagelschuer et al., the authors summarize current knowledge on deep brain stimulation in pediatric acquired dystonia, covering short- and long-term motor and non-motor effects... Check out the paper here 👇👇 doi.org/10.3389/fneur.2026.1735832
Title card for publication: Deep brain stimulation in children with acquired dystonia
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Stimulating Brains @stimulatingbrains.org · 28/07/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/64-balint-var…
Quote card for Stimulating Brains #64: Balint Varkuti – Making Use of Side-Effects: Redefining Brain Computer Interfaces with Ceregate. Quote from Balint Varkuti: I think at Brain Lab, it was really when I think I was at the first surgery that was done with the new software we made.
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Lead-DBS @lead-dbs.org · 28/07/2026
Classic publication using Lead-DBS: In this article by Sarica et al., the authors tested MRI‑guided transcranial ultrasound stimulation (TUS) of M1, GPi, or occipital control in Parkinson’s patients with STN electrodes and... Check out the paper here 👇👇 doi.org/10.1126/scitranslmed.ady1883
Title card for publication: Transcranial ultrasound stimulation of motor networks in Parkinson’s disease informed by local field potential dynamics
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Stimulating Brains @stimulatingbrains.org · 27/07/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/63-mark-mcaul…
Quote card for Stimulating Brains #63: Mark McAuley & Susan Boehnke – Patient-led Research, Patient-Centered Care and Neuroscience Education. Quote from Mark McAuley & Susan Boehnke: I'm really a proponent of getting more undergraduates involved in the research process because I think they're just a great way to make amazing future doctors, scientists, and industry leaders potentially.
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Lead-DBS @lead-dbs.org · 27/07/2026
Classic publication using Lead-DBS: In this article by Balachandar et al., the authors recorded GPi-DBS local field potentials in 10 children longitudinally and showed that status dystonicus is a distinct state charac... Check out the paper here 👇👇 www.nature.com/articles/s41467-025-…
Title card for publication: Status dystonicus is a distinct state characterized by pallidal beta-band activity
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Lead-DBS @lead-dbs.org · 24/07/2026
New publication using Lead-DBS: In this article by Mazurek et al., the authors tested whether ICD‑10‑derived frailty (RAI) and age predicted outcomes after unilateral MRgFUS thalamotomy for essential tremor in 481 patients, finding ne... Check out the paper here 👇👇 doi.org/10.1002/mds.70435
Title card for publication: Frailty and Tremor Recurrence after Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) Thalamotomy for Essential Tremor: An Age-Driven Association
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Andreas Horn @andreashorn.org · 27/07/2026
New perspective out @thelancetneuro.bsky.social w Anna Latorre, Marie Vidhailet et al. – where we further develop the idea that appendicular dystonia preferentially maps to BG networks while axial/cervical forms to cerebellar interations. Check it out here 👇👇 www.thelancet.com/journals/lan...
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Stimulating Brains @stimulatingbrains.org · 26/07/2026
🎧 Tune in here 🎶 🎧 👇👇 stimulatingbrains.org/70-rees-cosgr…
Quote card for Stimulating Brains #70: Rees Cosgrove – When Neurosurgery Chooses You: Rediscovering the Lost Art of Lesions and the Future of Brain Stimulation. Quote from Rees Cosgrove: No, but so I don't think I really, I have a feeling, neurosurgery chose me.
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Lead-DBS @lead-dbs.org · 26/07/2026
Classic publication using Lead-DBS: In this article by Leplus et al., the authors tested somatotopy of the sensory ventroposterior thalamus in six chronic neuropathic pain patients using directional deep brain sti... Check out the paper here 👇👇 onlinelibrary.wiley.com/doi/10.1002…
Title card for publication: Somatotopy of the sensory thalamus: inputs from directional deep brain stimulation in pain patients
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