Leading AIs from OpenAI, Anthropic and Google opted to use nuclear weapons in simulated war games in 95 per cent of cases

The absence of visual mental imagery, called aphantasia, occurs congenitally in up to 3% of the general population, but the brain regions responsible …

Background The benefits of amyloid-β monoclonal antibodies for Alzheimer’s disease are tempered by the risk of amyloid-related imaging abnormalities (ARIA). Detailed real-world characterization of ARI...

The lesion network mapping method links diverse brain lesions to similar functional brain networks, reflecting general brain organization rather than disorder-specific circuits.

Study shows criminality is associated with damage to a key brain pathway involved in emotional control and judgment

Objective Attention-deficit/hyperactivity disorder (ADHD) has been associated with decreased regional brain volume, yet no consistent localization has emerged across studies. This discrepancy has be...

Molecular Psychiatry - White matter disconnection in acquired criminality

Background Visual mental imagery, the ability to volitionally form perceptual representations without corresponding external stimuli, allows reliving of past events, solving problems and imagining the...

Nature Reviews Neurology, Published online: 01 May 2025; doi:10.1038/s41582-025-01091-wPlasma biomarker tests for Alzheimer disease are becoming increasingly reliable, which enables implementation in clinical settings in which cerebrospinal fluid analysis and PET scans are unavailable. However, a new study shows that some patients have discordant plasma and PET biomarker results. Clinicians need clear guidance to identify and manage patients who do not fit into standard clinical or biological categories.

Scientists have long been aware of a paradox of neurodegenerative disease – that as the brain deteriorates, in some patients creativity flourishes. Researchers have used imaging techniques to map cre...

Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.

This cross-sectional study examines National Institutes of Health and pharmaceutical industry investments in recent drug approvals.

This study using network mapping of meta-analytic data investigates whether creativity maps to a specific brain circuit and whether damage to that circuit aligns with creativity changes observed in pe...

This case-control study analyzes published cases of lesion-induced psychosisTo assess whether lesions that cause secondary psychosis have functional connections to a common brain circuit

How do you know you have heard right? Metacognition, the ability to assess and monitor one’s own cognitive state, is key to understanding human communication in complex environments. However, the foun...

This cohort study of more than 13 million individuals aged 14 to 65 years examines changes in the population-attributable risk fraction for cannabis use disorder associated with schizophrenia after li...

YouTube video by The Royal Society

In an unprecedented move, research-grant reviews have been suspended indefinitely at the world’s largest public funder of biomedical research.

Measuring metacognitive ability is one of the enduring challenges in cognitive science. The current paper develops formal tests of the quality of different measures and assesses how current metrics pe...

Researchers are learning what causes Alice in Wonderland syndrome, a rare neurological condition that can appear to warp bodies, time and reality itself

Researchers are learning what causes Alice in Wonderland syndrome, a rare neurological condition that can appear to warp bodies, time and reality itself

Three distinguished scientists on leaving academia to advance biomedical research

Our ability to identify associations between behaviour and brain imaging is important for uncovering markers of cognition and disease. Here, the authors illustrate the importance of the reliability of...