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Bahne Bahners

@bahnebahners.bsky.social
1.7K followers 484 following 59 posts

Research Fellow @ Brigham & Women‘s Hospital and Harvard Medical School interested in #DBS⚡️#MEG 🧲 #EEG 🧠 #Parkinson 🌷 @netstim.org scholar.google.com/citations?hl=de&…

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Reposted by Bahne Bahners
Andreas Horn @andreashorn.org · 18/04/2026
Which way best defines the optimal deep brain stimulation target in #Parkinsons? x-y-z coordinates? sweet spots? fiber tracts? whole-brain networks? @patriciazvarova.bsky.social has just answered this question: All of them. New study out now in AoN: onlinelibrary.wiley.com/doi/epdf/10....
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Marvin Petersen @petersenm.bsky.social · 23/02/2026
New preprint: Revisiting the methodological foundation of lesion network mapping. doi.org/10.64898/202... A thread.
doi.org
Revisiting the methodological foundation of lesion network mapping
Lesion network mapping (LNM) links focal brain lesions to distributed neural circuits by projecting lesion locations through a normative functional connectome. van den Heuvel and colleagues recently s...
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Andreas Horn @andreashorn.org · 27/02/2026
A recent @natneuro.nature.com paper analyzed lesion network mapping and raised concerns about the validity of the method. See below 👇 for our response. www.biorxiv.org/content/10.6...
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Network Stimulation Institute @netstim.org · 22/02/2026
Netstim on route to the DBS summit in Würzburg! Looking forward to seeing everybody soon!
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Network Stimulation Institute @netstim.org · 20/02/2026
For the first time, we characterized the Parkinson's Disease Response Network across space and time, simultaneously. Fantastic work led by @bahnebahners.bsky.social out in BRAIN now 👇👇
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The Science of Parkinson's @scienceofpd.bsky.social · 15/02/2026
Researchers report the identification of "a deep brain stimulation response network that resembles the previously defined MRI network & operates in the high beta band"; Maximal connectivity to this network was associated with optimal DBS outcomes academic.oup.com/brain/advanc...
academic.oup.com
The deep brain stimulation response network in Parkinson’s disease operates in the high beta band
Bahners et al. identify a brain network linked to optimal therapeutic outcomes in patients with Parkinson’s disease receiving deep brain stimulation. This
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Universität zu Köln @unicologne.bsky.social · 06/02/2026
🧠 Deep brain stimulation for Parkinson’s disease achieves its best results when a precisely defined brain network operating in the high beta frequency range is targeted. This was shown by a team @andreashorn.org @bahnebahners.bsky.social in both space and time for the first time.👇 uni.koeln/5LYV7
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Universität zu Köln @unicologne.bsky.social · 06/02/2026
🧠 Die Tiefe Hirnstimulation bei Parkinson zeigt ihre bestmögliche Wirkung, wenn ein präzises Gehirnnetzwerk im Beta-Frequenzbereich (20–35 Hz) stimuliert wird – das zeigt ein Team um @andreashorn.org @bahnebahners.bsky.social jetzt erstmals gleichzeitig räumlich und zeitlich👇 youtu.be/ZrREFuDI-as
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Bahne Bahners @bahnebahners.bsky.social · 30/01/2026
🚨 New research alert: What happens at the cortex during pallidal #DBS in patients with cervical #dystonia? 🧠 ⚡ ---> www.researchgate.net/publication/... <-----
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David Brang @dbrang.bsky.social · 20/01/2026
Interpreting EEG requires understanding how the skull smears electrical fields as they propagate from the cortex. I made a browser-based simulator for my EEG class to visualize how dipole depth/orientation change the topomap. dbrang.github.io/EEG-Dipole-D... Github page: github.com/dbrang/EEG-D...
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Michael Okun @michaelokun.bsky.social · 25/12/2025
Can Christmas calm the Parkinson's brain? Feldmann, Neumann colleagues describe in a paper in Movement Disorders how Christmas alters brain signals recorded from deep brain stimulation systems in the setting of Parkinson’s disease. @parkinsondotorg.bsky.social #christmas #xmas
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Jonathan Peelle @jpeelle.bsky.social · 23/12/2025
Looking forward to reading this paper (see thread). 👀 #neuroskyence
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PessoaBrain @pessoabrain.bsky.social · 23/12/2025
**Rethinking the centrality of brain areas in understanding functional organization** New paper I anticipate will become a classic in neuroscience and a must-read for students at all levels. Understanding brain function beyond brain areas. #neuroskyence www.nature.com/articles/s41...
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Andreas Horn @andreashorn.org · 19/12/2025
What is the status of DBS for epilepsy? Find out in our new review/metaanalysis spearheaded by @laurenahart.bsky.social & Garance Meyer in JNNP: pubmed.ncbi.nlm.nih.gov/40666371/ A 🧵 — please RT for reach! 🙏
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Yangfan Peng @yangfanpeng.bsky.social · 13/12/2025
🥳Excited to share our latest human multipatch paper, now out in @natneuro.nature.com 🧠 We studied the cellular and synaptic physiology of human L2–3 pyramidal neurons and identified subtype-specific local connectivity rules across individuals. www.nature.com/articles/s41... Join us: penglab.de
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 01/12/2025
Longitudinal Changes in Cortical Response Dynamics with Deep Brain Stimulation to the Subcallosal Cingulate for Treatment-Resistant Depression www.biorxiv.org/content/10.1101/202…
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JAMA Neurology @jamaneurology.com · 22/11/2025
Long-term adaptive deep brain stimulation (aDBS) provided tolerable, effective, and safe therapy in persons with Parkinson disease whose symptoms were previously stable while receiving continuous DBS. ja.ma/3M2ENGl
Figure 2. Changes in Motor Diary shows raw data for change in on-time: ST aDBS, DT aDBS, and Motor diary data: ST aDBS, DT aDBS. Graphs show individual participants, observed mean time h/d, asleep, off-time, on-time with TD, and without TD.
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Bahne Bahners @bahnebahners.bsky.social · 23/11/2025
#neuroskyence
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jhirschmann.bsky.social @jhirschmann.bsky.social · 30/10/2025
New paper out in npj Digital Medicine! Fayed Rassoulou demonstrates how electrophysiology + machine learning can help identify the optimal contact for deep brain stimulation. rdcu.be/eNgG1
rdcu.be
Electrophysiological signatures predict the therapeutic window of deep brain stimulation electrode contacts
npj Digital Medicine - Electrophysiological signatures predict the therapeutic window of deep brain stimulation electrode contacts
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Sarang Dalal @sarangnemo.bsky.social · 08/10/2025
📈🧠 We're looking for brains! 🧠📈 Postdoc + PhD positions are available to help pioneer fetal MEG with optically pumped magnetometers, measuring prenatal responses to sound and light to understand how we start making sense of the world even before we're born. 🐣 Please get in touch to hear more!
schematic of fetal OPM-MEG
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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · 25/10/2025
There's still time to apply! #neurojobs
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Lauren Hart @laurenahart.bsky.social · 24/06/2025
🧠 ⚡️ Preprint alert ⚡️ 🧠 I️n the most comprehensive review of DBS in epilepsy, with 124 studies, 1,210 patients, and 20 anatomical targets we map where stimulation works best and why. Deep Brain Stimulation for Epilepsy: Optimal Targeting and Clinical Outcomes www.researchgate.net/publication/...
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Alexander Li Cohen @drdrxanderli.bsky.social · 17/06/2025
Thrilled our ADHD network mapping work is now out in Annals of the Child Neurology Society, and honored to be featured on the cover! 🔗 Full article: onlinelibrary.wiley.com/doi/full/10.... @childneurosoc.bsky.social @bostonchildrens.bsky.social @simonwarfield.bsky.social @braincircuits.bsky.social
onlinelibrary.wiley.com
Coordinate Network Mapping of Focal Brain Volume Differences in ADHD Reveals Common Patterns That Lack Specificity: A Systematic Review
Objective Attention-deficit/hyperactivity disorder (ADHD) has been associated with decreased regional brain volume, yet no consistent localization has emerged across studies. This discrepancy has be...
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Sergiu Groppa @segroppa.bsky.social · 10/06/2025
Take a look at our new work, providing explanations for the mechanisms of deep brain stimulation, with insights into the modulation of motor- premotor cortex activity from mouse-based and translatable research methodologies for future therapy solutions shorturl.at/5Atjh
shorturl.at
Frequency- and layer-specific effects of high-frequency STN stimulation on mouse motor cortical areas in vivo
Abstract. High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective evidence-based therapy for Parkinson’s disease; howe
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Benjamin Kay @benjaminkay.bsky.social · 22/05/2025
My med school textbook says stimulants like Ritalin treat hyperactivity by “stimulating” the brain’s attention and cognitive control systems. We studied children taking stimulants in the ABCD Study, and the largest differences were actually in arousal and reward networks! Check out our preprint!
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Lukas Goede @lukasgoede.bsky.social · 22/05/2025
Tremor is a common symptom across many neurological disorders. But is there a shared tremor circuit across disorders - one that could guide treatment, regardless of diagnosis? We think: yes. Our study is out now in @natcomms.nature.com: 🔗 www.nature.com/articles/s41... 🧵 A thread.
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Lukas Goede @lukasgoede.bsky.social · 19/05/2025
Big thanks to @patriciazvarova.bsky.social and @bahnebahners.bsky.social for their wonderful contributions, and to @andreashorn.org for his mentorship on this project! Read the full study here: onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Patient Selection in Deep Brain Stimulation: A Role for Transcranial Direct Current Stimulation to Enhance the Levodopa Challenge?
Dopaminergic medication and deep brain stimulation (DBS) improve motor symptoms in Parkinson's disease (PD), but levodopa response alone may not predict DBS outcomes. We retrospectively analyzed 19 P....
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Bahne Bahners @bahnebahners.bsky.social · 09/04/2025
🚨 🥁 Preprint alert: The Deep Brain Stimulation Response Network in Parkinson’s Disease Operates in the High Beta Band ->> www.researchgate.net/publication/... <<--
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Frederic Schaper @fredschaper.bsky.social · 24/03/2025
Is generalized epilepsy a seizure of the whole brain or a specific brain network? In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome. Paper: nature.com/articles/s41... A 🧵 below:
nature.com
A generalized epilepsy network derived from brain abnormalities and deep brain stimulation - Nature Communications
Ji et al. identify an idiopathic generalised epilepsy network that links heterogeneously distributed brain abnormalities to a common brain network and deep brain stimulation sites which reduce general...
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Jim Thompson @jimthommo.bsky.social · 25/03/2025
This is amazing work!
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Andreas Horn @andreashorn.org · 04/04/2025
Congratulations to *Dr.* @barbarahollunder.bsky.social for a summa cum laude in her PhD earned at Charité today! Barbara is already a rock-star with multiple awards including the @dbsthinktank.bsky.social rising star award, an @ohbmofficial.bsky.social merit award and multiple German awards. …
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Prof. Vladimir Litvak @vlitvak.bsky.social · 04/04/2025
Well done @barbarahollunder.bsky.social and I believe the excellent mentors deserve a lot of credit as well.
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Colin Hoy @colinwhoy.bsky.social · 01/03/2025
Very helpful to see this comprehensive view of what dopamine and DBS are doing in the cortico-basal ganglia loops!
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Andreas Horn @andreashorn.org · 21/03/2025
Interested in an update on connectomic and adaptive deep brain stimulation for obsessive compulsive disorder? Take a look at our summary of this exciting field and how things could be brought together out now in BPS: www.biologicalpsychiatryjournal.com/article/S000... A brief 🧵
biologicalpsychiatryjournal.com
Deep Brain Stimulation response circuits in Obsessive Compulsive Disorder
In the field of deep brain stimulation (DBS), two major themes are currently making significant progress. First, the framework of connectomic DBS, in which circuits that are associated with improvemen...
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Earl K. Miller @earlkmiller.bsky.social · 12/03/2025
Yeah they do Traveling Waves Integrate Spatial Information Through Time Blog: kempnerinstitute.harvard.edu/research/dee... Paper: arxiv.org/abs/2502.06034 #neuroscience
kempnerinstitute.harvard.edu
Traveling Waves Integrate Spatial Information Through Time - Kempner Institute
The act of vision is a coordinated activity involving millions of neurons in the visual cortex, which communicate over distances spanning up to centimeters on the cortical surface. How do […]
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Andreas Horn @andreashorn.org · 03/03/2025
Had a wonderful conversation with Jonathan Downar on @stimulatingbrains.org – Jonathan is one of the folks who may make you feel you have been wasting your time for the last years – but does so in a positive, very inspiring way. Certainly one of the key thought leaders in the neuromod space! Tune in
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Thomas S. Binns @tsbinns.com · 18/02/2025
Excited to have my PhD project paper exploring the network mechanisms of neuromodulation accepted for publication! We show how deep brain stimulation and medication exert a shared modulation of motor network synchrony in Parkinson's disease.
Schematic summary of therapeutic effects of dopamine and deep brain stimulation (DBS) across spatial, spectral, and temporal scales in Parkinson's disease.
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Andreas Horn @andreashorn.org · 28/02/2025
Very excited by this paper led by Savir Madan & @laurenahart.bsky.social, which introduces the first self-train dataset for learning Lead-DBS and a nice tool to self-assess how well localizations compare to expert solutions.
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Andreas Horn @andreashorn.org · 27/02/2025
Look what arrived in the mail today as a belated New Years gift – thanks Christian Lüscher & lab – very honored to be a remote lab member!
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Andrew Pines @andrewpines.bsky.social · 26/02/2025
Super cool talk by @karaannjohnson.bsky.social showing how evoked resonant neural activity (ERNA) can be used to guide DBS localization, direction, and (possibly even) more!
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Andrew Pines @andrewpines.bsky.social · 26/02/2025
Awesome work by @barbarahollunder.bsky.social showing how 4 different diseases that can all be modulated at a tiny nuclei (STN) can be differentiated by white matter tracts (to be a little hipster: I’ve been a fan of this since it was a preprint)
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Andreas Horn @andreashorn.org · 26/02/2025
Second talk of @barbarahollunder.bsky.social at #BrainStimConf – great overview on STN-DBS for multiple disorders 👇👇 (paper here: www.nature.com/articles/s41...)
nature.com
Mapping dysfunctional circuits in the frontal cortex using deep brain stimulation - Nature Neuroscience
Hollunder et al. identify networks where deep brain stimulation reduces symptoms for Parkinson’s disease, Tourette’s syndrome, dystonia and obsessive-compulsive disorder. This revealed a fronto-rostra...
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Andrew Pines @andrewpines.bsky.social · 26/02/2025
Really thought-provoking talk by @julianneumann.bsky.social going over many things, including STN DBS but not Sinemet decreases cortical beta, and a super interesting theory about closed-loop timing of stimulation to beta phase
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Andreas Horn @andreashorn.org · 17/02/2025
I am excited to announce that I will be founding an institute for network stimulation at the University Hospital Cologne – already this coming May!
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Andreas Horn @andreashorn.org · 12/02/2025
Do lesions that cause psychosis fall into a common brain network? Exciting new work by @andrewpines.bsky.social, @shansiddiqi.bsky.social and colleagues – tweetorial below by the first author, paper here: jamanetwork.com/journals/jam...
jamanetwork.com
Mapping Lesions That Cause Psychosis
This case-control study analyzes published cases of lesion-induced psychosisTo assess whether lesions that cause secondary psychosis have functional connections to a common brain circuit
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Michael Fox @foxmdphd.bsky.social · 13/02/2025
Can damage to a specific brain circuit cause psychosis? New paper out today by @andrewpines.bsky.social @shansiddiqi.bsky.social says Yes! Hub of the circuit is in the hippocampus - great alignment with NMDA encephalitis. @braincircuits.bsky.social
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Andrew Pines @andrewpines.bsky.social · 12/02/2025
What brain regions are involved in causing psychotic symptoms? Take a moment away from the existential dread about the future of science, and join me in this summary of some incredibly cool stuff that could help patients! 1/n🧵
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Can Sarica @cansarica.bsky.social · 08/02/2025
Honored to be invited by @foxmdphd.bsky.social to give a talk on mapping tremor response zones in thalamus @harvardmed.beky.social this Friday. It was a privilege to discuss with brilliant scientists like Dr. Cosgrove, Dr. Horn @andreashorn.org, Dr. Bubrick, and Dr. Siddiqi @shansiddiqi.bsky.social.
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Andreas Horn @andreashorn.org · 19/01/2025
Interested in modeling DBS induced white matter activations? Konstantin Butenko has a new preprint on all the options available within OSS-DBS / @lead-dbs.org including Electric Field Projections and probabilistic Pathway Activation Modeling: www.medrxiv.org/content/10.1...
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nanditharajamani.bsky.social @nanditharajamani.bsky.social · 17/01/2025
This is going to be fantastic! 🙌 Aysu will talk about her multi center project on different targets for Tourette syndrome & Dr. Gunduz will give a fantastic talk on how engineering can play a role in neuroscience! Register here!!! stimulatingbrains.org/talk-series/ I can't wait!!!
stimulatingbrains.org
Talk Series – Stimulating Brains
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