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BD²

@bipolardiscoveries.org
595 followers 90 following 190 posts

BD² is a collective force shortening the time it takes to get from scientific breakthroughs to improved clinical care for bipolar disorder. bipolardiscoveries.org

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BD² @bipolardiscoveries.org · 29/09/2026
💈💈New funding opportunity: BD² is seeking additional clinic sites in the U.S., Canada & U.K. to join the Integrated Network, connecting longitudinal #BipolarDisorder research with collaborative learning to improve care. 💰 Up to $2.35M/site over 5 years 📅 Apply by Jan 15: bit.ly/4hj0iyJ
BD² funding opportunity graphic on a dark teal background. Text reads: “Funding Opportunity Now Open. Up to $2.35M per clinic site over 5 years. Apply by Jan. 15.”
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BD² @bipolardiscoveries.org · 25/09/2026
💈💈New funding opportunity: BD² Discovery Research Cycle 5 seeks proposals on #BipolarDisorder’s biological mechanisms, especially women’s health, sex differences & hormones, or projects using the BD² Integrated Network. 🧠 📅 Webinar: Oct 7 | LOIs: Nov 20 🔗 Apply: bit.ly/4hj0iyJ #Neuroskyence
Graphic with a blue textured background. A white box with a yellow outline reads “Funding Opportunity Now Open” with subheading “$15 million is available to support bold, multidisciplinary research”. A yellow button reading “Apply by Nov 20” is in the bottom right corner, and the BD² logo is in the bottom left corner.
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BD² @bipolardiscoveries.org · 24/09/2026
Applicant webinar: Discovery Research Cycle 5 💈💈 On Oct 7, BD² will review the RFA scope, eligibility, LOI requirements, open science expectations & key dates—and answer applicant questions. 👉 Register: bit.ly/4ydpIow 👉 Apply: bit.ly/4hj0iyJ
Graphic with blue leftside panel titled “Discovery Research RFA Webinar” with the date and time listed as October 7 at 2:00pm ET. A yellow button below says “Register Now.” On the right, headshots are pictured on a gray textured background for Daniel Pham, PhD, Head of Science and Innovation and Kelsey Barcomb, PhD, Program Manager, Discovery Research. The BD² logo is in the bottom righthand corner.
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BD² @bipolardiscoveries.org · 22/09/2026
💈💈BD² is awarding more than $13M in grants to 3 new Discovery Research teams studying the biology of mood state switching in #BipolarDisorder. The teams are led by @drlaramieduncan.bsky.social, PhD, Susan Dymecki, MD, PhD, & Akira Sawa, MD, PhD. 🔗 bit.ly/4rrCblZ #BipolarDisorder #Neuroskyence
Graphic with a blue textured side panel on the left reading "BD² Awards Over $13 Million in Grants to Understand the Mechanisms of Mood State Switching in Bipolar Disorder." Beneath the title, the institutions Harvard Medical School, Johns Hopkins University, and Stanford University are listed. On the right, 11 principal investigators' headshots are pictured. The BD² logo is in the bottom lefthand corner.
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BD² @bipolardiscoveries.org · 17/09/2026
Breakthroughs happen faster when science is open, shared, and built on together. ⚡ For #OpenScienceWeek, the BD² team shares what open science looks like in practice and why it’s central to changing the future of #BipolarDisorder research. 🔗 www.bipolardiscoveries.org/bd2-open-sci...
Quote graphic featuring Cara Altimus, PhD, CEO of BD², with her headshot on a dark teal background. Text reads: “BD² enables bold and collaborative science so people living with bipolar disorder can thrive. To make this happen, we need as many minds and ideas working on this as possible. That’s the core of why open science is embedded in everything BD² does.”
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BD² @bipolardiscoveries.org · 16/09/2026
From preprints to publications to shared data, open science makes research easier to access, test, and build on. This #OpenScienceWeek, dive into BD² research across bioRxiv, PMC, and Zenodo to explore the outputs shaping the future of bipolar disorder research.
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BD² @bipolardiscoveries.org · 13/08/2026
📬 Looking for the latest in bipolar disorder research? Subscribe to BD²’s newsletter for scientific findings, funding opportunities, and news from across the BD² community: www.bipolardiscoveries.org/newsletter-signup/
bipolardiscoveries.org
Thrive Updates
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BD² @bipolardiscoveries.org · 05/08/2026
🔬AKAP11 is one of the strongest risk genes identified for #BipolarDisorder. The protein it encodes interacts with GSK3β, a proposed target of lithium. Connections like this could deepen our understanding of bipolar disorder and help inform more targeted treatments. ▶️ bit.ly/3SiTBnj
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BD² @bipolardiscoveries.org · 03/08/2026
🧠📈Great to see the BD² community at the 2026 NYC Neuromodulation Conference—sharing ideas, connecting across the field, and bringing our neuromodulation teams together. @foxmdphd.bsky.social @umnbme.bsky.social @stanfordmedicine.bsky.social @weillcornell.bsky.social @sinaibrain.bsky.social
Group picture of the attendees of the NYC Neuromodulation Conference standing together smiling at the camera.
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BD² @bipolardiscoveries.org · 30/07/2026
🧬 1,500 participants. 12 sites. Whole-genome sequencing underway. BD²’s Integrated Network combines genetic, clinical, and real-world data to advance research and outcomes for people with #BipolarDisorder. Hear from Cara Altimus, PhD, & Benjamin Neale, PhD, on The Genetics Podcast: bit.ly/3SiTBnj
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BD² @bipolardiscoveries.org · 28/07/2026
⏰ One week left to apply for the BD² Data Science Fellowship. Postdocs can apply for up to $125,000 per year over two years to analyze existing BD² datasets and advance data-driven #BipolarDisorder research. Apply by July 31: bit.ly/4ajk768
Graphic with a purple and blue gradient background reading “Funding Opportunity Now Open” in large blue letters. A subheader underneath reads “New funding is available to support up to 8 data science projects for early-career researchers.” The BD² logo is in the bottom left corner and a turquoise button reading “Apply by July 31” is in the bottom right corner.
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BD² @bipolardiscoveries.org · 23/07/2026
🚀 We’re hiring a Director of Partnerships to build BD²’s development program and help fuel breakthrough discoveries in bipolar disorder research. We’re looking for an exceptional leader to shape our strategy, grow our community, and scale our impact. 🔗 Apply: bit.ly/3TaXrQ4
A graphic with a blue textured background. A white box in the center with a lime green outline reads “We’re Hiring: Director of Patnerships” with the subheading “We’re looking for a development professional to scale our impact.” A lime green button in the bottom right corner says “Apply Now.”
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BD² @bipolardiscoveries.org · 21/07/2026
🧬 Applications are open for the BD² Data Science Fellowship. Postdocs can apply for up to $125,000 per year over two years to analyze existing BD² datasets and advance data-driven #BipolarDisorder research. Apply by July 31: bit.ly/4ajk768
Graphic with a purple and blue gradient background reading “Funding Opportunity Now Open” in large blue letters. A subheader underneath reads “New funding is available to support up to 8 data science projects for early-career researchers.” The BD² logo is in the bottom left corner and a turquoise button reading “Apply by July 31” is in the bottom right corner.
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BD² @bipolardiscoveries.org · 14/07/2026
🧠 BD² PI @ignaciosaezphd.bsky.social and his team are using deep brain stimulation and epilepsy-based brain recordings to better understand the circuits that drive mood changes in bipolar disorder. The more we learn about these circuits, the closer we get to treatments tailored to brain biology.
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BD² @bipolardiscoveries.org · 08/07/2026
📊 A breakthrough method in genetic sequencing With support from BD², scientists at the Broad Institute developed the Blended Genome Exome (BGE), a low-cost genome sequencing method that delivers high quality genetic data. Read the paper: www.nature.com/articles/s41...
nature.com
A blended genome and exome sequencing method captures genetic variation in an unbiased and cost-effective manner - Nature Genetics
Blended genome exome (BGE) is a sequencing method that captures genetic variation in an unbiased and cost-effective manner. Applying BGE to sequence samples from underrepresented populations leads to ...
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BD² @bipolardiscoveries.org · 07/07/2026
🔬 BD² Lead PI Ziad Nahas, MD, MSCR, and his team at @umnbme.bsky.social are using advanced tools to better understand the individual neurobiological patterns that underlie mood episodes. This precision matters for diagnosis, prediction, and ultimately, more personalized care.
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BD² @bipolardiscoveries.org · 02/07/2026
📬Want to stay updated with all things BD²? Never miss a funding opportunity or scientific finding with our Thrive Updates Newsletter: www.bipolardiscoveries.org/newsletter-s...
bipolardiscoveries.org
Thrive Updates
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BD² @bipolardiscoveries.org · 30/06/2026
Siloed data limits what we can learn. Real progress in bipolar research comes from integration — aligned data collection, collaboration across teams, and transparent public release. 🔗 www.bipolardiscoveries.org/our-work/data-release ▶️ bit.ly/4cJpyMk
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BD² @bipolardiscoveries.org · 22/06/2026
BD² is connecting longitudinal research with clinical care to advance precision medicine for bipolar disorder. @dr-altimusprime.bsky.social and @emilybaxi.bsky.social joined the Empowered Patient Podcast to discuss BD²’s data release, longitudinal cohort study, and more. 🎧: bit.ly/3SmB8GB
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Accelerating Bipolar Disorder Research to Transform Diagnosis and Treatments with Cara Altimus and Emily Baxi BD2
Podcast Episode · Empowered Patient Podcast · June 18 · 22m
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BD² @bipolardiscoveries.org · 16/06/2026
🔬 What does bipolar disorder research look like from inside a Learning Health Network? Watch Michigan Medicine’s “Inside the Study” webinar to hear researchers, clinicians, and participants discuss the BD² Integrated Network and its work to improve diagnosis and treatment. ▶️: bit.ly/4flWKfL
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Inside the Study
The Heinz C. Prechter Bipolar Research Program presents "Inside the Study" featuring research and lived experience experts, Dr. Kelly Ryan, Christine Grimm, N.P., Dr. Alexandra Vinson, and Sarah, and moderated by Jack DiCarlantonio. This webinar highlights the BD²: Breakthrough Discoveries for Thriving with Bipolar Disorder research study. In 2023, the Heinz C. Prechter Bipolar Research Program was named as one of the six inaugural institutions in the BD² Integrated Network to engage people living with bipolar disorder in a long-term research study and build a rich database to better understand the condition, its treatment, and to support improvements in care. The BD² Integrated Network has since expanded its clinical sites to 11 institutions across the United States and Canada. Along with the long-term studies and databases, the BD² Integrated Network sites are working together to design and implement a Learning Health Network (LHN) for bipolar disorder. Learn more about the background of the Prechter Program’s role in the BD²: Breakthrough Discoveries for Thriving with Bipolar Disorder study, what participation is like, what the team is finding so far, and more. Learn more: - Heinz C. Prechter Bipolar Research Program: https://medresearch.umich.edu/labs-departments/centers/prechter-program - BD²: Breakthrough Discoveries for Thriving with Bipolar Disorder: https://medresearch.umich.edu/labs-departments/centers/prechter-program/research/breakthrough-discoveries-thriving-bipolar-disorder - BD² Integrated Network: https://www.bipolardiscoveries.org/our-work/integrated-network/
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BD² @bipolardiscoveries.org · 11/06/2026
🧬 Genetic discovery is transforming our understanding of bipolar disorder. Now, it’s about translating that knowledge into better care. On The Genetics Podcast, Cara Altimus & Benjamin Neale discuss how genetics + longitudinal data can drive more precise diagnosis & treatment. 🎧 bit.ly/3SiTBnj
Cara Altimus and Benjamin Neale transposed onto a red background. The Genetics Podcast logo is in the top left corner. The podcast title: "How BD² is using genetics and deep phenotyping to transform bipolar research with Cara Altimus and Ben Neale is written across the bottom in white text. The bottom right corner reads "Ep 243."
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BD² @bipolardiscoveries.org · 10/06/2026
We believe science moves faster when barriers come down. BD² is proud to endorse @asapbio.bsky.social’s Preprint Policy Framework to advance a new way of communicating scientific research, accelerate open science, and connect discovery to care. 🔗 asapbio.org/preprint-pol...
asapbio.org
Advancing Openly Licensed Preprints: Aligning Across A Standard Preprints Policy Framework – ASAPbio
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BD² @bipolardiscoveries.org · 09/06/2026
🧠 “By releasing these data to the public, we can massively expand the capacity to generate insights—beyond any single investigator or network.” — Katherine Burdick, PhD, on the BD² Integrated Network data release 🧬Explore the release: bit.ly/4vLaaHO ▶️Watch more: bit.ly/4cJpyMk
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BD² @bipolardiscoveries.org · 03/06/2026
Matthew Woodworth, a member of Team Tam (@jennymtam.bsky.social), shares how lived experience and a fascination with brain organoids inform his work to better understand bipolar disorder. His story underscores why open conversation, empathy, and research all matter. 🔗Read more: bit.ly/4nXO95f
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BD² @bipolardiscoveries.org · 01/06/2026
🧬 New: BD² Data Science Fellowship BD² is accepting applications for postdocs using data science to generate new insights from existing BD² datasets. New funding is available to support up to 8 fellowships advancing #BipolarDisorder research. Apply by July 31: bit.ly/4ajk768
Graphic with a purple and blue gradient background reading “Funding Opportunity Now Open” in large blue letters. A subheader underneath reads “New funding is available to support up to 8 data science projects for early-career researchers.” The BD² logo is in the bottom left corner and a turquoise button reading “Apply by July 31” is in the bottom right corner.
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BD² @bipolardiscoveries.org · 28/05/2026
We’re growing 🌱 Hiring a Science Communications Manager to help shape BD²’s voice and translate complex bipolar disorder research into clear, compelling stories. This role spans content strategy, science translation, digital channels, researcher engagement, & media support. Apply: bit.ly/3PQYa7F
Graphic with a textured blue gradient background and BD² logo in the bottom left corner. A large white rounded rectangle with a yellow outline contains the headline “We’re Hiring” in bold navy text. Below, navy text reads, “We’re seeking a Science Communications Manager to translate science into impact.” A yellow button in the lower right reads “Apply Now.”
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BD² @bipolardiscoveries.org · 28/05/2026
Women’s health is essential to understanding #BipolarDisorder. For International Day of Action for Women’s Health, hear from BD²’s Women’s Health Workgroup on reproductive transitions, research gaps, and more equitable care. 🎬 bit.ly/49VDsu0
Graphic with a purple textured background and the quote “For a long time, women have been underrepresented or oversimplified in mental health research, even though there are real biological, clinical, and social factors that shape how bipolar disorder shows up and how care is delivered.” Attributed to Emily Baxi, BD² Integrated Network Program Director. The BD² logo is in the bottom right corner.
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BD² @bipolardiscoveries.org · 26/05/2026
BD² Discovery Research Program Director Daniel Pham, PhD, recently spoke at the NCI Center for Cancer Research Fellows and Young Investigators Colloquium. He discussed his career journey and the opportunities for early-career researchers at philanthropic organizations.
Daniel Pham smiling behind the podium at the NCI Research Fellows and Young Investigators Colloquium.
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BD² @bipolardiscoveries.org · 21/05/2026
Progress in mental health research requires better data, deeper understanding, and care shaped by lived experience. Through the Integrated Network, BD² participants are helping advance patient-centered bipolar disorder care. 🔗 Explore our first dataset bit.ly/4tF5f9N #MentalHealthAwarenessMonth
Quote from a researcher at McMaster University reading "By integrating biological, psychological, and social data, we can move beyond trial-and-error care toward a more precise, patient-centered approach." Displayed on a green textured background.Quote from a researcher at UCLA reading "Grounding symptoms in biology can counter stigma and help patients better understand — and engage in — their care." Displayed on a green textured background.Quote from a researcher at UCLA reading "Participants are grateful that a project like BD² exists. Many have mentioned that they feel there is still so much to learn about bipolar disorder, and they hope that this research can help lead the way." Displayed on a green textured background.Quote from a researcher at University of Michigan reading "A few themes have emerged across participants: resilience, the ability to find meaning in their disorder, and deep gratitude that this study exists. Many share our goal of improving the lives of others living with bipolar disorder." Displayed on a green textured background.
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BD² @bipolardiscoveries.org · 19/05/2026
📚 Philanthropic funding, strategic collaboration, and real-time data sharing help BD² move #BipolarDisorder research forward faster. Read more from @dr-altimusprime.bsky.social’s conversation with Paul Karon from Inside Philanthropy:
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BD² @bipolardiscoveries.org · 15/05/2026
💡BD² is redefining collaborative mental health science—with philanthropy driving connection, discovery, and real-world impact grounded in lived experience. CEO Cara Altimus, PhD, spoke with Inside Philanthropy about how this model is advancing progress toward better care: tinyurl.com/mjunfss9
tinyurl.com
Inside a Megadonor-Backed Funder’s Fight to Treat Bipolar Disorder
The BD2 initiative has been assembling an international network to coordinate research and standards of care. Backers include Sergey Brin and Dalio Philanthropies.
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BD² @bipolardiscoveries.org · 12/05/2026
Charles Lynch, PhD, and the BD² Discovery team at @weillcornell.bsky.social, in collaboration with @stanfordmedicine.bsky.social, are leveraging individualized brain imaging to map circuits and inform targeted interventions in #bipolardisorder.
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BD² @bipolardiscoveries.org · 07/05/2026
We’re growing our team 🌱 Hiring a PhD/postdoc-level intern to support program ops and research coordination across a global bipolar disorder research network. From meeting prep and grant tracking to decks and newsletters, you’ll turn complex science into clear, actionable work. 🔗: bit.ly/4tlBaLO
A graphic with a textured blue background and a large white text box outlined in yellow. The headline reads “Internship Opportunity Now Open,” with supporting text: “We’re hiring an intern to support bold, multidisciplinary research.” A yellow button reads “Apply Now,” and the BD² logo appears in the bottom left.
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BD² @bipolardiscoveries.org · 06/05/2026
📊 We’re sharing the largest multi‑modal psychiatric dataset—built across 6 sites with shared standards, aligned protocols & rigorous QA. The result: trusted, accessible data ready to drive new discoveries and collaborations. 🔗 www.bipolardiscoveries.org/our-work/dat...
Blue graphic with a title reading “BD² Integrated Network Data Release” and a subtitle reading “Largest multi-modal psychiatric dataset now available to accelerate breakthroughs in bipolar disorder”. The BD² logo is in the top righthand corner.
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BD² @bipolardiscoveries.org · 30/04/2026
🔍 What’s driving momentum in bipolar disorder research? At BD²’s poster session, researchers shared how studying bipolar disorder more deeply and collaboratively helps link science with real patient experience. That connection is what’s accelerating discovery. 🎥
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BD² @bipolardiscoveries.org · 29/04/2026
Mental health is brain health. In STAT, Eric J. Nestler, MD, PhD, BD² Discoveries Scientific Chair, and colleagues argue that the divide between psychiatric & neurological conditions is a mistake and limits progress. Earlier, integrated approaches are key to improving lives. 🔗 bit.ly/4eLTg5S
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BD² @bipolardiscoveries.org · 28/04/2026
“It’s not just about investing in bipolar research—it’s about improving care and building a community.” — @dr-altimusprime.bsky.social, PhD BD² is expanding access to data to spark ideas and drive impact for people with bipolar disorder. 📺: bit.ly/4cJpyMk
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BD² @bipolardiscoveries.org · 24/04/2026
🧠 @foxmdphd.bsky.social and his BD² Discovery Research team at @mgbresearch.bsky.social are mapping brain circuits tied to specific bipolar symptoms—unlocking targeted neuromodulation treatments rather than one-size-fits-all approaches.
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BD² @bipolardiscoveries.org · 23/04/2026
📊"The public release of data means more investigators, clinicians, and individuals with lived experience can start answering these questions. The time is now." - Mark Frye, MD, BD² SSC member and Integrated Network co-chair, on BD²’s first data release 🧠Learn more about the release: bit.ly/4vLaaHO
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BD² @bipolardiscoveries.org · 21/04/2026
Our first public data release is live, shaped by the lived experiences of our participants. Years in the making, this dataset lays the groundwork to accelerate discovery, advance precision medicine, and support people with bipolar disorder in thriving: now and in the future. 🔗 bit.ly/4tF5f9N
Yellow graphic with a white outlined illustration of five people in the top right corner. White text reads "615 participants included in de-identified data."
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BD² @bipolardiscoveries.org · 17/04/2026
📢 We're excited to welcome Erin Ross, BD²’s Director of Operations. Erin brings deep experience in science philanthropy and operations, and she will help align strategy and execution to advance bipolar disorder research. Welcome, Erin!
Headshot of Erin Ross smiling outdoors wearing a blue blazer over a white blouse.
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BD² @bipolardiscoveries.org · 16/04/2026
What’s next for addiction medicine and recovery care? Emily Baxi, PhD—BD²’s IN Program Director—joins leaders in science, policy, and patient advocacy at Hope on the Horizon. Hosted by @sciam.bsky.social Custom Media + WVU Rockefeller Neuroscience Institute April 22 | DC 🔗 luma.com/hopeonhorizon
luma.com
Hope on the Horizon: The Science and Communities Redefining Addiction Care · Luma
An exclusive event co-hosted by Rockefeller Neuroscience Institute and Scientific American Custom Media --------- Please join us on April 22nd for an engaging…
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BD² @bipolardiscoveries.org · 15/04/2026
🧬 What’s powering the next wave of bipolar disorder research? Investigators across the BD² network are exploring bioenergetics, organoids, proteomics, and new shared data—working toward a future where everyone with bipolar disorder can thrive. Hear from a few of them at our latest Poster Session. 🎥
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BD² @bipolardiscoveries.org · 07/04/2026
When clinicians and researchers work together toward the goal of improving lives for those with #bipolardisorder, collaboration shifts how research progresses. Hear from Tracy Young-Pearse, PhD, on BD²'s integrated approach in the latest #InvestigatorInsights. 🧠
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BD² @bipolardiscoveries.org · 03/04/2026
🔬Our network is doing amazing work! Learn more about what the CircaVent team is doing to drive discovery in #bipolar research.
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BD² @bipolardiscoveries.org · 03/04/2026
Bipolar disorder research has long been slowed by fragmented data. BD²’s first Integrated Network data release helps change that, bringing together rich, longitudinal data to support more connected, collaborative discovery. 🔗See what more connected data unlocks: bit.ly/4tF5f9N
Graphic of rainbow data points over a black background with the white text reading "BD² Integrated Network Data Release" across the center.
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Reposted by BD²
The Wyss Institute at Harvard University @wyssinstitute.bsky.social · 30/03/2026
Katharina Meyer is welcoming. She's a great host & collaborates with members of the multidisciplinary CircaVent Team. They are developing brain organoids to study bipolar disorder to identify better therapeutics. Learn more about Katharina & her work in this month’s #HOWyss. #WorldBipolarDay
wyss.harvard.edu
Katharina Meyer on improving our understanding and treatment of bipolar disorder
The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and be...
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BD² @bipolardiscoveries.org · 30/03/2026
On #WorldBipolarDay, we've released the largest integrated dataset in psychiatry and created a new cornerstone for #bipolar research. Clinical, imaging, wearable, and biological data—combined longitudinally and standardized across sites. 🧠📈 🧪 Learn more: www.bipolardiscoveries.org/our-work/dat...
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BD² @bipolardiscoveries.org · 20/03/2026
Be sure to tune in at 1pm PT/4pm ET today to hear BD² CEO Cara Altimus speak at the UCLA Brain Health Summit! www.youtube.com/live/GiUU8ge...
youtube.com
UCLA Health Brain Health Summit 8 AM - 5:30 PM PT Friday, March 20 & Saturday, March 21, 2026
YouTube video by BRI UCLA
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BD² @bipolardiscoveries.org · 19/03/2026
🧠 Women’s mental health research has historically been underfunded and underprioritized, with much of women’s health research focused on obstetrics and gynecology. This #WomensHistoryMonth, BD²’s Women’s Health Workgroup is helping close gaps by studying how bipolar disorder can differ in women.
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