Biological media such as airway mucus and extracellular matrix are usually viewed as transport barriers that particles cross by passive diffusion or with internal engines. We show instead that a parti...

Abstract. CRISPR diagnostics enable sensitive detection of infectious diseases, with the RNA endonuclease Cas13a providing specific, amplification-free RNA

Launched in 2023, our BioEnginuity Impact Grant helps STEM doctoral students aim their research toward the greater social good. The grant offers students the flexibility to reimagine their research in...

A multiplexed RNA detection method exploits crRNA-dependent variability in Cas13a activity on RNA targets for kinetic barcoding and can be used to distinguish among SARS-CoV-2 variants in clinical sam...

Macrophages recognize and phagocytose opsonized target cells, including those coated with IgG antibodies. This process relies on binding of IgG to Fcγ receptors (FcγR) expressed on the macrophage surf...

Cornell et al. show that target cells with low cortical tension induce macrophages to preferentially trogocytose, or engulf in small fragments, whereas target cells with high cortical tension tend tow...

Cornell et al. show that target cells with low cortical tension induce macrophages to preferentially trogocytose, or engulf in small fragments, whereas target cells with high cortical tension tend tow...

The flexibility of tethered molecules, such as those bound to biological membranes, is an important property that can influence molecular height, m...

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Author summary Schistosomiasis is a neglected tropical disease that impacts hundreds of millions of people worldwide. Patients with Schistosoma haematobium shed parasite eggs in their urine, which can...

Nature Communications - Cell-cell fusion is fundamental to physiological processes such as muscle formation and viral infection. Here, the authors show that the proteins embedded on the plasma...

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This article includes recent preLights posts that discuss preprints in the field of cell biology.Target cell tension regulates macrophage trogocytosis by Caitlin E. Cornell et al.Read the preLight.Vis...

Macrophages are known to engulf small membrane fragments, or trogocytose, target cells and pathogens, rather than fully phagocytose them. However, little is known about what causes macrophages to choo...