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Carlos Francisco Ng

@carlosfng.bsky.social
15 followers 22 following 2 posts

🇵🇦👨🏻‍🔬⚙️🔧🔬🧬🦠💉🧪

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Reposted by Carlos Francisco Ng
Fletcher Lab @fletcherlabucb.bsky.social · 02/09/2026
What if you had a light-triggered starting gun for #CRISPR diagnostics? Meet LUCas, a light-controlled #Cas13a system that stays silent until you need it. Now published in @narjournal.bsky.social. Congrats to all the authors! #moleculardiagnostics academic.oup.com/nar/article/...
academic.oup.com
LUCas: Light-Uncaged Cas13a using photocleavable interfering guide RNAs
Abstract. CRISPR diagnostics enable sensitive detection of infectious diseases, with the RNA endonuclease Cas13a providing specific, amplification-free RNA
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Reposted by Carlos Francisco Ng
Fletcher Lab @fletcherlabucb.bsky.social · 27/04/2026
Congratulations to Carlos (@carlosfng.bsky.social) for being a recipient of the 2026 Outstanding Graduate Student Peer Mentor Award. Images courtesy of Laure Andrillon.
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Reposted by Carlos Francisco Ng
Fletcher Lab @fletcherlabucb.bsky.social · 02/04/2026
In our new work published in @natbiomedeng.nature.com in collaboration with @theottlab.bsky.social and @doudna-lab.bsky.social, we introduce "interfering" guide RNAs (igRNA) for CRISPR-Cas13a that regulate enzyme activity after activation. Congrats to all the authors! www.nature.com/articles/s41...
nature.com
Programmable kinetic barcoding for multiplexed RNA detection with Cas13a - Nature Biomedical Engineering
A multiplexed RNA detection method exploits crRNA-dependent variability in Cas13a activity on RNA targets for kinetic barcoding and can be used to distinguish among SARS-CoV-2 variants in clinical sam...
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Reposted by Carlos Francisco Ng
Fletcher Lab @fletcherlabucb.bsky.social · 12/02/2026
Check out our latest preprint: LUCas! A direct light control of Cas13 trans-cleavage activity. Congrats to all the authors: Carlos (@carlosfng.bsky.social), Deepak (@deepakkrish.bsky.social), Andres, and Aymeric. www.biorxiv.org/content/10.6...
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Carlos Francisco Ng @carlosfng.bsky.social · 16/12/2025
Congratulations Caitlin! #trogocytosis #macrophages
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Carlos Francisco Ng @carlosfng.bsky.social · 27/11/2024
Hola Bluesky!
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