iiinova — where your digital self keeps evolving

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Zak Swartz @zakswartz.bsky.social · 06/08/2026

Shining stars! 🌟 🎉 Our latest preprint is out, led by postdoc Beverly Naigles and research assistant Brian McGonagle, two amazing members of the lab and @mblscience.bsky.social community. www.biorxiv.org/content/10.6...

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Kristina Stapornwongkul @kstapornwongkul.bsky.social · 06/08/2026

First published teamwork of the lab 🎉! We wrote a review about emerging concepts of how metabolism promotes, regulates and changes during gastrulation. We hope it will be useful for anyone interested in the emerging field of developmental metabolism. www.sciencedirect.com/science/arti...

sciencedirect.com

A metabolic view of gastrulation: Coordinating signalling, epigenetics and morphogenesis

Gastrulation is the morphogenetic process by which the single-layered pluripotent epiblast is reorganised into the three germ layers and the basic bod…

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Cornelia Schwayer @cschwayer.bsky.social · 03/08/2026

I will be opening my research group at the Max Delbrück Center later this year to unravel the principles governing the unique context sensing capacity of the liver www.mdc-berlin.de/schwayer and am looking for enthusiastic PhD applicants.

mdc-berlin.de

Schwayer Lab

The mammalian liver possesses a regenerative capacity that is unmatched by any other organ. Following injury, liver epithelial cells can proliferate or even change their identity, enabling the organ t...

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Marina B. Cuenca @cuencam15.bsky.social · 31/07/2026

Sad to be saying goodbye to Drosophila, but excited to get this work out on bioRxiv! If you are interested in the interplay of tissue flows and cool ways to mess them up, this read is for you :) Thanks to colleagues and co-authors! www.biorxiv.org/content/10.6...

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Zimeng Wu @zimengwu33.bsky.social · 30/07/2026

Got to try out another microscope woo! 8 positions stitched taken on the new @Bruker lightsheet this morning

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AIC at Janelia @aicjanelia.bsky.social · 30/07/2026

During the final group project at #IALSJanelia, participants are combining their knowledge of light sheet microscopy, large data handling, and tracking to measure macrophage motion in a zebrafish tail. The data shown here was taken on our SiMView microscope by @anjanja1024.bsky.social.

Color visualization of microscopy data. Each color corresponds to a point in time, ranging from 0 hours (purple) to 12 hours (yellow). The structures in the image correspond to macrophages in a zebrafish tail.

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Yanlan Mao @yanlanmao.bsky.social · 30/07/2026

This epic paper, which has been a heroic 10 year journey for the lead author, Ricardo Barrientos, is finally out in Cell today! Many thanks to all co-authors, especially Billie Meadowcroft and Andela Saric for their beautiful MD simulations www.cell.com/cell/fulltex...

cell.com

Basement membrane turnover controls cell shape

Basement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane ada...

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Krista Koeller @kristalerista.bsky.social · 28/07/2026

Thinking about how plants and animals, who independently evolved multicellularity, both landed on the spatial expression of transcription factors as the way to figure out where all the parts go.

A diagram showing the MADS domains patterning a flower. Gene expression goes from the outside in with A,B,C,D, and E domains. E is expressed in all cells. In some cells, there is A and E expression, those cells develop into sepals. Cells with A, B, and E expression become petals. Those with B, C, and E become stamens. Those with C and E become carpals, and C, D, and E cells become ovules.

Hox gene expression in the fly. The genes are shown in order on the chromosome and appear in the same order in the fly. The first gene patterns the mouth, the second the forehead, the third, the back of the head, etc.

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Institute of Science and Technology Austria (ISTA) @istaresearch.bsky.social · 29/07/2026

📢 Calling for applicants! 📢 The NOMIS–ISTA Fellowship Program offers postdoctoral researchers the freedom and security to explore high-risk concepts at the intersection of multiple scientific disciplines. Apply now: bit.ly/49ivtnW

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Yuting Irene Li @irene-yuting-li.bsky.social · 27/07/2026

I’m starting at the Hubrecht Institute at a new group leader from September. I will be hiring a PhD student through the PhD program ⬇️ If you, or anyone you know, is interested in theoretical biophysics, I will be very excited to hear from them — please send inquiries to my ISTA email for now :)

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David Brückner @davidbrueckner.bsky.social · 28/07/2026

How can morphogenesis produce complex outcomes, reproducibly? 🤔 We show: remodeling & growth allow buffering against noise & prevent elastic coarsening Led by Nico Romeo, in collab w/ @npmitchell.bsky.social 👉 arxiv.org/abs/2607.23907

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Joël Lemière @joellemiere.bsky.social · 27/07/2026

New preprint! How does a cell "know" how big to make its nucleus? This has puzzled biologists since the 1800’s. We show the answer is physics: colloid osmotic pressure. 🧵1/5

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James Briscoe @jamesbriscoe.bsky.social · 27/07/2026

It's not often single author primary research papers are published in our field & it's even rarer when the author is a Nobel Prize winner Check out the new work by Eric Wieschaus in @dev-journal.bsky.social Flattening maternal gradients in Drosophila embryo journals.biologists.com/dev/article/...

journals.biologists.com

Maternal patterning in early Drosophila embryos: how much information can single maternal gradients supply?

Highlighted Article: Comparison of the patterning capacity of Drosophila embryos that have only one of the three maternal gradients known to control anterior posterior patterning.

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Rebecca D. Burdine, PhD @rburdine1.bsky.social · 26/07/2026

Day4 #2026SDB #Devbio Despite ridiculous AV issues, the session on morphogemesis has been mind-blowing. This is why I love Dev Biol! /1

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Zebrafish Rock! 🎃 @zebrafishrock.bsky.social · 26/07/2026

The first 22 hours of #zebrafish development in under one minute. Credit to @zebrafish007.bsky.social in #WeinsteinLab at NIH. #ZebrafishZunday 🧪

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epithelial mechanics fan club @epimechfc.bsky.social · 26/07/2026

How do tissues safely remove cells? Join me, @marija-matejcic.bsky.social in this perspective on the past, present and future of epithelial cell extrusion 🧵 0/16

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Rachel Lee, PhD @scientistrachel.bsky.social · 25/07/2026

Lattice light sheet data taken by the participants of #IALSJanelia 2026, with guidance from @cmhobson.bsky.social. I rendered the actin dynamics using #AGAVE 🔬

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Joel Lüthi @joelluethi.bsky.social · 24/07/2026

Do you want to learn more about OME-Zarr viewers, where they stand today and what's being developed at the moment? On August 24th at 4pm CEST, we will hear about 3 different OME-Zarr viewers and user stories for each. www.biovisioncenter.uzh.ch/en/events/Up... (1/5 🧵)

biovisioncenter.uzh.ch

Open Bioimaging Practices Meetup August 2026

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Turlier lab @turlierlab.bsky.social · 24/07/2026

Very happy to have this work finally published! How do embryos sculpt their shape? We map the contractile & adhesive forces shaping early C. elegans embryos. With K. Yamamoto @ittoku04.bsky.social G. Charras' lab @gcharras.bsky.social & my team @turlierlab.bsky.social shorturl.at/xv7G5 1/6

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Akankshi Munjal @akankshi.bsky.social · 24/07/2026

Excited to share our latest! www.biorxiv.org/content/10.6... This was a highly collaborative endeavor– the best way to do science. We asked how a developing tissue achieves the right shape despite all the variability along the way. Short answer: Hydrostatic pressure. Read on for the long answer!

3D-rendered confocal image of the embryonic zebrafish inner ear (otic vesicle) showing fluorescently labeled cell membranes. Three translumenal epithelial pillars span the lumen, partitioning it into the three semicircular canals (purple arrow: anterior canal; yellow arrow: posterior canal; white arrow: lateral canal)

3D rendering of the segmented otic vesicle lumen at 3 days post-fertilization, showing the three connected fluid-filled compartments corresponding to the anterior, posterior, and lateral semicircular canals. The segmentation shows the characteristic geometry of the canals and the spaces partitioned by the transluminal epithelial pillars.

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M. Brent Hawkins @homeobox.bsky.social · 23/07/2026

I am excited to open my lab at @ibioillinois.bsky.social in Spring 2027! We will use zebrafish & other fishy friends to reveal the genetic basis of large scale changes in the vertebrate body plan, and how this impacts both human health and evolution. Join me at UIUC! 🧬🧫🔬 www.hawkinslaboratory.com

A confocal image of a zebrafish embryo featured on the webpage for the Hawkins Lab at UIUC

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Ricardo Henriques @henriqueslab.bsky.social · 21/07/2026

🚀🔬 Can cell shape, signal and movement tell us about a cell's future? #DeepLearning studies now predict cell fate from #microscopy. Together w Rita, @mariodelr.bsky.social, @inesmcunha.bsky.social, @juliettegriffie.bsky.social + @guijacquemet.bsky.social👇 www.preprints.org/manuscript/202607.1414/v1

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Varsha Mathur @varshamathur.bsky.social · 21/07/2026

So happy to share our new paper out now in @natmicrobiol.nature.com! We establish Pirsonia-Coscinodiscus as a model pathosystem and uncover how this tiny parasite infects and kills bloom-forming marine diatoms 🌊🦠 rdcu.be/fuQyF

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Dipanjan Ghosh @fishics.bsky.social · 21/07/2026

Such a beautiful 3D time-lapse!

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Journal of Cell Biology @jcb.org · 20/07/2026

Michaud, @andrewgoryachev.bsky.social, von Dassow, @xenresearchcenter.bsky.social et al. identify a versatile cortical pattern-forming circuit based on #Rho, F-#actin, Ect2, & RGA-3/4 rupress.org/jcb/article/... 📕 In "Collective Behaviors and Self-Organization in Cells" rupress.org/jcb/collecti...

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Kari Herrington @kahsage.bsky.social · 18/07/2026

I have the print copy!! It's so exciting to see my art on the cover and @henrydebelly.bsky.social's paper in print! Thanks Orion! @oweinerlab.bsky.social!

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Vicki Metzis @vmetzis.bsky.social · 17/07/2026

How does an embryo generate the right cells in the right place? Delighted to share our latest findings on how neural crest cells acquire vagal or trunk identities Spoiler alert: The timing & combination of CDXs preconfigures cell identity & distinct HOX states www.biorxiv.org/content/10.6...

biorxiv.org

Temporally distinct CDX programmes preconfigure vagal and trunk neural crest

Neural crest cells (NCCs) are progenitor cells vital in establishing the head, heart, gut and peripheral nervous system of vertebrate embryos. Disruptions to NCC development underlie neurocristopathie...

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allen institute @alleninstitute.org · 17/07/2026

Our #CellLineOfTheWeek is beta-catenin - illuminating adherens junctions! 🧫 Our hiPSC lines & plasmids – fluorescently-tagged to illuminate structures – are openly available to support scientific discovery. 📦 Distributed by @coriellinstitute.bsky.social & @addgene.bsky.social #FluorescenceFriday

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Keri Martinowich @martinowk.bsky.social · 17/07/2026

Fresh off the🔬for #FluorescenceFriday from @ishbeldelrosario.bsky.social - pretty RNAscope as part of our continued exploration of spatially-organized populations of D1R-expressing island populations in nucleus accumbens of human 🧠. Excited to be bringing some key updates to the data resources soon!

Microscopy image of fluorescently labeled cell markers in the human nucleus accumbens

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Benoit Ladoux @bladoux.bsky.social · 17/07/2026

What determines how epithelial cells divide when shape cues disappear? Our new work shows that division follows the axis of maximal stress anisotropy. This “principal-stress rule” links mechanics, proliferation, and homeostasis. Amazing work from @luanger.bsky.social. www.biorxiv.org/content/10.6...

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Claire L. Evans @theuniverse.bsky.social · 15/07/2026

I was lucky enough to spend a few days at the Kavli Institute of Theoretical Physics recently, observing an interdisciplinary group of scientists as they grappled with the limits of language in the face of biological complexity. My scene report: clairelevans.substack.com/p/report-fro...

clairelevans.substack.com

Report from Goleta

An account of three days haunting the halls of the Institute for Theoretical Physics.

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Teng-Leong Chew @scopeshifu.bsky.social · 15/07/2026

🧪 @aicjanelia.bsky.social and @scientistrachel.bsky.social have just published a new quantitative tool, OpticalFlow3D, for tracking amorphous motion in 3D. Try it out and let us know what you think! tinyurl.com/OpticalFlow3D

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Wolfram Pönisch @wolframponisch.bsky.social · 14/07/2026

I'm looking for a postgraduate intern to join my group at @humantechnopole.bsky.social, modelling how pili dynamics drive bacterial motility and aggregation. Finishing a master's in physics, computational biology, or a similar field? Get in touch: careers.humantechnopole.it/job/Internsh...

careers.humantechnopole.it

Internship - Pönisch Lab

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Stacey Ogden 🦔 @labogden.bsky.social · 13/07/2026

Happy #MicroscopyMonday! This movie shows the ZPA of a 🐭 limb bud. Cells expressing SHH are labeled 🌈. Notice the dynamic signaling protrusions extending from SHH-expressing ZPA cells - so cool! Membranes of cells not expressing SHH are 🔵 🧪 🔬 👩‍🔬 #DevBio #SciArt Credit: @christinaadaly.bsky.social

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Quanta Magazine @quantamagazine.org · 11/07/2026

Researchers thought that what enabled complex fluids to break apart was their elasticity. But a crack in a nonelastic simple fluid has them questioning that idea. www.quantamagazine.org/we-know-simp...

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Kristina Stapornwongkul @kstapornwongkul.bsky.social · 08/07/2026

The DevSTEM meeting @istaresearch.bsky.social was a fantastic opportunity to connect with the Vienna devbio and stem cell community. A huge thanks to all the early-career researchers for presenting and discussing their research! Looking forward to next year's edition @viennabiocenter.bsky.social!

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Ankita Jha @ankita13jha.bsky.social · 07/07/2026

Excited to share our new paper, now published in Nature Cell Biology! 🎉 We asked a fundamental question in cell biology: How do cells maintain polarity while migrating? Especially how do cancer cells navigate confined spaces? www.nature.com/articles/s41556-026-01981-1

nature.com

CD44 restricts EGFR mobility to polarize cytoskeletal signalling modules driving bleb-based migration - Nature Cell Biology

Jha et al. show that the transmembrane protein CD44 restricts EGFR mobility to maintain an EGFR–PI3K–Rac gradient during bleb-based cell migration.

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Pauli Group (posts by Andi Pauli) @pauligroup.bsky.social · 07/07/2026

The #EZM2026 (European Zebrafish Society @ezsociety.bsky.social meeting) is in full swing! More than 500 (not only zebra-)fish researchers from all over the world gather here in Vienna for the next 5 days to discuss science, exchange ideas and make new connections. #Fish #Zebrafish #Friends

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Ritu Raman @rituraman.bsky.social · 07/07/2026

Out today in PNAS: We show that dynamic "4D" forces can spatially pattern angiogenesis in a PIEZO1-dependent manner. Excitingly, changing force patterns over time enables redirecting sprouting trajectories, forming complex branched geometries: www.pnas.org/doi/10.1073/... #TissueEngineering

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Julia Sero @cellmorphosero.bsky.social · 07/07/2026

#TubulinTuesday Reposting an old favourite - breast cancer cell grown in a low dose of taxes for a long time. It's swirling peripheral actin is winding microtubules like yarn on a spindle, pulling its DNA along into the maelstrom.

A huge cell with a ring of yellow microtubules and purple actin around the edge. In amongst the ri g are small circles of blue DNA. The center has a large irregular blob of blue DNA and a clear area where there are a few wiggle microtubules going from the center to the outer ring.

Close up of a section of the huge cell, with a ring of parallel yellow microtubules with embedded cyan DNA spots in it. The misshapen cyan nucleus is in the bottom. A long yellow thread connects the nucleus to the other ring, and there is a blob of DNA at the point where they meet, also training a long thread back to the nuclear DNA.

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Valentin Dunsing-Eichenauer @dunsingvalentin.bsky.social · 06/07/2026

Already out for a while as the final version: Our @elife.bsky.social paper presenting an experimental and computational pipeline for whole mount deep imaging and multi-scale analysis of organoid systems: elifesciences.org/articles/107... A great collaboration during my postdoc in Marseille.

elifesciences.org

A quantitative pipeline for whole-mount deep imaging and analysis of multi-layered organoids across scales

The Tapenade pipeline enables single-cell, whole-mount 3D quantification in dense multilayer organoids, linking spatial gene co-expression and nuclear deformation to emerging tissue-scale organization...

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