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Teng-Leong Chew

@scopeshifu.bsky.social
2K followers 1.5K following 20 posts

Director, Advanced Imaging Center at HHMI Janelia Research Campus, USA. Founder, Africa Microscopy Initiative.

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Reposted by Teng-Leong Chew
Chad Hobson @cmhobson.bsky.social · 29/07/2026
This was quite an exciting project that has been years in the making, hopefully we can open up light sheet microscopy to some new samples!
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Teng-Leong Chew @scopeshifu.bsky.social · 28/07/2026
🧪 Want to image specimens that require air-liquid interface on a microscope with water-dipping lenses such as the lattice light sheet system? @aicjanelia.bsky.social, @cmhobson.bsky.social and TokaiHIT have just made that a reality. Check out our new paper: www.nature.com/articles/s44...
nature.com
Adapting upright light sheet fluorescence microscopy for imaging at air-liquid interface - npj Imaging
npj Imaging - Adapting upright light sheet fluorescence microscopy for imaging at air-liquid interface
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Reposted by Teng-Leong Chew
Stephan Huveneers @huveneerslab.bsky.social · 28/07/2026
How do endothelial cells interact while migrating? Together with @jesseaic.bsky.social @scopeshifu.bsky.social @aicjanelia.bsky.social, we used #Cryo-SIM and #FIB-SEM to reveal a surprising diversity of nanoscale plasma membrane curvatures at asymmetric junctions. rupress.org/jcb/article/...
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Reposted by Teng-Leong Chew
AIC at Janelia @aicjanelia.bsky.social · 20/07/2026
This morning at #IALSJanelia we're getting started with some microscopy fundamentals in a lecture by @cmhobson.bsky.social 🔬
A photo of people in a conference room. A man stands at the front next to a large projector screen. The screen shows a presentation slide on image formation.
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Reposted by Teng-Leong Chew
AIC at Janelia @aicjanelia.bsky.social · 21/07/2026
We're exploring Fourier transforms at #IALSJanelia. In addition to applying them computationally in #Fiji, we're performing them optically with the help of a @thorlabs.bsky.social optics kit run by @cmhobson.bsky.social!
A photograph of optics equipment on a table. The Fourier pattern is projected onto a white piece of paper, while the image pattern is seen in the upper right corner of the photo.
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Reposted by Teng-Leong Chew
AIC at Janelia @aicjanelia.bsky.social · 23/07/2026
This afternoon's imaging lab at #IALSJanelia is all about subcellular structures, highlighted here by myosin (white) and actin (orange). These membrane ruffles were captured on our lattice light-sheet microscope by @cmhobson.bsky.social
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Reposted by Teng-Leong Chew
AIC at Janelia @aicjanelia.bsky.social · 21/07/2026
For our first live cell imaging lab of #IALSJanelia 2026, we're exploring the migratory behavior of neutrophil-like HL60 cells. Confocal microscopy by @anjanja1024.bsky.social 🔬
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Reposted by Teng-Leong Chew
AIC at Janelia @aicjanelia.bsky.social · 19/07/2026
We're kicking off #IALSJanelia 2026 with a keynote lecture by @scopeshifu.bsky.social. Our teaching team is excited to get to know all our participants and start two weeks of talking about microscopy! 🔬
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Teng-Leong Chew @scopeshifu.bsky.social · 15/07/2026
🧪 @aicjanelia.bsky.social and @scientistrachel.bsky.social have just published a new quantitative tool, OpticalFlow3D, for tracking amorphous motion in 3D. Try it out and let us know what you think! tinyurl.com/OpticalFlow3D
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Teng-Leong Chew @scopeshifu.bsky.social · 10/04/2026
🧪 From ~2500 applications to various international microscopy workshops, we delineate fascinating regional patterns in research foci and microscopy usage across the globe. These data could help form the basis for tailoring microscopy workshop curricula to local needs. tinyurl.com/32c3fzvk
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Teng-Leong Chew @scopeshifu.bsky.social · 28/01/2026
🧪 We are excited to share this novel open access paper on Phasor Mixing Coefficient to analyze colocalization, developed by folks @i2janelia.bsky.social and @aicjanelia.bsky.social. This is also the first technical paper jointly published with our sister imaging center @malacridalab.bsky.social!
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Teng-Leong Chew @scopeshifu.bsky.social · 02/06/2025
There's no algorithm on earth that can beat the predictive power of fortune cookies.
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Reposted by Teng-Leong Chew
Nature Methods @natmethods.nature.com · 06/05/2025
Global efforts in microscopy dissemination have revealed the importance of setting technology adoption capable of producing scientific outcome as an end goal. Learn more here in a Comment from Leong Chew and colleagues! @scopeshifu.bsky.social www.nature.com/articles/s41...
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Teng-Leong Chew @scopeshifu.bsky.social · 06/05/2025
A year ago, global imaging leaders and funders met at @hhmijanelia.bsky.social to discuss #microscopy dissemination to underserved communities and the potential solutions. Are the challenges a misstep or a missed step? Here is the white paper to address that question. tinyurl.com/y6ycehzf
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Teng-Leong Chew @scopeshifu.bsky.social · 27/02/2025
It often takes more than just technical validation to propel #microscopy technology to the end users. Here we detail the comprehensive stewardship model of the AIC (@aicjanelia.bsky.social) in "De-risking transformative microscopy technologies for broad adoption" tinyurl.com/4yat36ce 🧪 "
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Teng-Leong Chew @scopeshifu.bsky.social · 13/02/2025
🧪Job opening at Janelia @hhmijanelia.bsky.social Integrative Imaging platform for a bioimage analyst. Please repost.
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Teng-Leong Chew @scopeshifu.bsky.social · 24/01/2025
I am immensely excited and proud of the official launch of Imaging Southeast Asia (iSEA) yesterday. This is one of the fastest growing #microscopy communities I have witnessed across the globe! Check them out, and join at imagingsea.org 🧪
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Reposted by Teng-Leong Chew
Seán Doran @theseaning.bsky.social · 17/11/2024
'Crimson Star' 3 wavelengths of July 2023 data from Solar Dynamics Observatory is repaired, processed, blended & graded to rgb with music by Chris Zabriskie. Edited from 40 minute 4k original. Credit: SDO / NASA / AIA / Seán Doran
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Teng-Leong Chew @scopeshifu.bsky.social · 14/11/2024
Sharing this very nice, multi-part, blog by a current visitor to the Advanced Imaging Center @aicjanelia.bsky.social at HHMI Janelia Research Campus👇. Our next proposal call to this unique open-access microscopy program will be announced in early 2025. lantsandlaminins.com/2024/11/04/y...
lantsandlaminins.com
You can see a lot by looking – Using the best microscope in the world – Part 1
Part 1 of a blog update of our trip to do microscopy at Janelia HHMI
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Reposted by Teng-Leong Chew
Zach Marin @zacsimile.bsky.social · 13/11/2024
Check out this nice list of open-source microscope control software, maintained by Alfredo Rates: smartmicroscopy.org/resources/
smartmicroscopy.org
Resources
Anything missing? Let us know in the forum! Repositories Here you can find multiple open repositories that may help you to develop smart microscopes in your lab! Software and tools Here there is a …
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Reposted by Teng-Leong Chew
Dr. Allyson Sgro @allysonsgro.bsky.social · 09/11/2024
Very excited to be invited to this school next year. Students and postdocs: this is an amazing opportunity, you should apply!
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Reposted by Teng-Leong Chew
Rachel Lee, PhD @scientistrachel.bsky.social · 12/02/2024
The deadline to apply for the Imaging Across Length Scales bootcamp is this Thursday, Feb 15!
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Teng-Leong Chew @scopeshifu.bsky.social · 14/12/2023
Biennial, free microscopy bootcamp at Janelia. Learn how hypothesis formulation, quantitative experimental design, advanced microscopy and data analysis facilitate exploration across biological length scales. Please circulate! Apply by Feb. 15 @ www.aicjanelia.org/imagingacros...
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Teng-Leong Chew @scopeshifu.bsky.social · 16/10/2023
Not only did I realize my dream of hiking on a glacier, I participated in the ritual of drinking from the Sólheimajökull in Iceland! 😎
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