How tumors exploit cell states and how we're learning to engineer our own

Spatial multiomics, scarless editing, and xenocortical mice: advances across scales and systems

How spatial transcriptomics, metastasis secrets, and yeast are redefining cancer research

Over the course of a lifetime, somatic mutations accrue in normal human cells, causing variation in cell phenotype and engendering somatic evolution with outcomes ranging from the adaptive immune syst...

Uncovering cancer’s hidden architectures, and how to target them

From enhancer atlases to spatial multi-omics: decoding cancer’s epigenetic and microenvironmental complexity

How tumors talk to their surroundings, and how we’re learning to listen

From neural memory to microbial manipulation: how sex, epigenetics, and bacteria redefine resilience and disease

Epithelial-to-mesenchymal transition (EMT) involves cancer cells shifting between different states linked to tumor progression. Here, the authors use single-cell multiomics and CRISPR/Cas9-mediated lo...

From cell competition to genetic edges: how intercellular interactions redefine disease and discovery

How spatial context, summary statistics, and scalable frameworks are transforming biology

From spatial counterfactuals to tumor microbiomes: how context reshapes biology

The invisible foundations of cancer: early malignancy, epigenetic plasticity, and the tools to see it all

Mapping biology across space, time, and scale with AI-powered discovery

How cells communicate, adapt, and age across space and time

Single-cell high-throughput sequencing, a major breakthrough in life sciences, allows to access the integrated molecular profiles of thousands of cells in a single experiment. This abundance of data p...

Virtual spatial transcriptomes, tumor ecotypes, and the hidden logic of cell communication

Reference-free discovery, spatial resolution, and targeting tumor states

From metastatic clones to synthetic DNA: how cell fate is written and rewritten

Nature - Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity

When cells compete, learn, and communicate

We are looking for a Group Leader in applied artificial intelligence in (bio)medical research at VIB.AI & UGent, Belgium

From synthetic genomes to multi-omics cells: integrating and rewriting biology

Not all of it, but some scientists are too eager to believe their own hype

Memory, models, and massive data: rethinking cancer across scales

Rewiring cancer biology across scales: from 3D genomes to microbial niches

When context controls cancer: oxygen, space, niches and chromatin

From ecDNA to epigenomic priming: modeling what averages miss

Systemic programs and structured models across cancer and aging

Chart tumour evolution using cutting-edge long-read and single-cell multiomics Who we are The Integrative Cancer Genomics lab (Jonas Demeulemeester) is embedded within the VIB – KU Leuven Center for ...

How space, context, and uncertainty reshape cancer and single-cell biology

The NOMIS Foundation, in collaboration with the DFG-funded Munich Cluster for Systems Neurology (SyNergy), invites exceptional early-career scientists from around the world to apply for elite…