Abstract. The Mnemonic Similarity Task (MST) is sensitive to age-related cognitive decline in humans and has been adapted for rodents using 3D objects, whe

It’s a powerful analogy that captured the popular imagination, but the biological reality is quite different

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Yasir Raouf examines how dimethyl sulfoxide (DMSO), a deceptively simple molecule, spans organic chemistry, cryobiology, medicine, and drug discovery. Diverse applications emerge from its highly polar...

A recent brain imaging study reveals that the reward system is hyper-connected to other social networks in autistic individuals. This heightened integration correlates with social communication differences and overlaps with specific genetic and chemical markers.

The hippocampus and neocortex are thought to undergo reorganization to incorporate new information during learning. How can we identify network states that indicate learning is occurring? In the hippo...

Analysis of the Allen Institute Visual Coding Neuropixels dataset revealed a ~5 Hz synchronization of visual cortical activity in awake, immobile mice. During bouts of this rhythm, synchronized cortical bursts coincided with changes in the occurrence of sharp-wave ripples (SWRs) and dentate spikes and in SWR properties. Cortical synchronization, SWRs, and dentate spikes were also coordinated with slower pupil-size fluctuation, revealing that awake SWRs are embedded within nested brainwide rhythms. ### Competing Interest Statement The authors have declared no competing interest. Swiss National Science Foundation, https://ror.org/00yjd3n13, PR00P3_208598, PR00P3_208598/2, TMPFP3_210606 Synapsis Foundation, 2022-CDA02 University Research Priority Program (URPP) Adaptive Brain Circuits in Development and Learning (AdaBD).

By Dr. Douglas R. Waverly, Professor Emeritus of Biochemistry, Yale University

I’ve long thought that part of the anger of the right wing over the handling of the covid pandemic was the realization that, “Someone else c...

In this case-control study, Chuang Liang and colleagues systematically compare brain aging patterns and biological processes across multiple common brain disorders.

Canada Research Chair (Tier II) in Muscle Mechanics, Faculty of Kinesiology in Calgary, AB...

Nature Human Behaviour, Published online: 01 October 2026; doi:10.1038/s41562-026-02573-7Tangible rewards are known to sharpen visual processing of associated objects. Tomić et al. show that an internal sense of confidence—acting as an intrinsic reward—similarly biases attention, revealing how the brain prioritizes limited resources.

Bipolar disorder (BIP) frequently co-occurs with heightened substance use (SU) and substance use disorders (SUDs). Although the strong co-occurrence of these heritable traits points to shared genetic…

Alcohol and nicotine are two leading causes of preventable deaths in the United States. Simultaneous co-use of alcohol and nicotine is rising, as is t…

This is the application form for the Cosyne 2027 Undergraduate Travel Grant Program. The deadline to apply is October 30th 2026.

The 38,000 testimonies are the largest body of evidence about children’s experiences in these institutions. The women say survivors should choose what happens to their histories — both painful and ill...

Alcohol and nicotine are two leading causes of preventable deaths in the United States. Simultaneous co-use of alcohol and nicotine is rising, as is t…

This article discusses research providing renewed reasons to revisit the utility of glutamatergic drugs for treating schizophrenia.

Molecular Psychiatry - Network adaptability governs resilience and susceptibility to social defeat

Ouellette et al. report that a 16p11.2 deletion induces a bioenergetic failure in brain endothelial cells. Activation of purinergic signaling via P2Y2 receptors restored endothelial function and impro...

Assistant Professor - Systems Neurophysiology

The arXiv preprint server originally democratized astronomical research by digitizing the circulation of early manuscripts and removing the financial barriers of journal subscriptions. However, a syst...