iiinova — where your digital self keeps evolving

Reposted by Jake Wintermute

Mon Mothra @flobbert.bsky.social · 14/09/2026

gonna turn this into a midi controller and make some of the worst music you've ever heard in your life

Jake Wintermute @synbio1.bsky.social · 14/09/2026

I'd like to get a 90s-era medical device console like this and install some kind of AI soundboard in it so it can be my sassy lab companion

070

Jake Wintermute @synbio1.bsky.social · 15/07/2026

So funny when preclinical biotechs sign these big biobucks deals. Oh you're going to get a 20% royalty on annual net sales exceeding $1 billion? Buddy the fog is gonna consume us in 2027. The fog is coming. The fog is coming. The fog is coming

042

Jake Wintermute @synbio1.bsky.social · 14/07/2026

Nobody there cares but I do it anyway

0111

Jake Wintermute @synbio1.bsky.social · 13/07/2026

Everyone wants to cure all diseases but nobody wants to do no hard ass biology experiments

74910

Jake Wintermute @synbio1.bsky.social · 11/07/2026

Can anyone who played CELLQuest on the original Becton Dickinson tell me if it was fun? Is it worth trying to vibe code an emulator for some retro gaming?

020

Jake Wintermute @synbio1.bsky.social · 27/05/2026

I look forward to the day when every lab instrument runs linux and the entire UI is just an MCP for my agents

050

Jake Wintermute @synbio1.bsky.social · 13/05/2026

If weeds can overgrow a fake lawn then it stands to reason that you could develop a strain of grass that would functionally replace the fake lawn except be real

141

Jake Wintermute @synbio1.bsky.social · 30/04/2026

How it feels to do biotech in 2026

214112

Jake Wintermute @synbio1.bsky.social · 28/04/2026

Bioproduct idea gluten-free damp dusters for the market of people with celiac disease who want to eat their scrub daddies

060

Jake Wintermute @synbio1.bsky.social · 24/04/2026

I am literally begging you to start a biotech company, literally any biotech company, and incorporate slop maximalism into your branding I am in love with biotech slop maximalism. I will do free work for you. I will shill whatever bioproduct or AI model thing you sell.

182

Jake Wintermute @synbio1.bsky.social · 20/04/2026

1) Apparently snails can eat graffiti 2) Apparently snails actively seek out graffiti to eat 3) ??? 4) Start a biotech company that sells snails for graffiti removal

4405

Reposted by Jake Wintermute

David Bikard @dbikard.bsky.social · 17/04/2026

Very proud of this work and all the efforts from my team and collaborators on this! You can now use DGRs for in vivo targeted hypermutagenesis in E. coli. We also included some early proof of concept in Yeast thanks to @seth-shipman.bsky.social !

08236

Jake Wintermute @synbio1.bsky.social · 12/04/2026

Cloud computing is a good product: versatile, scalable, on-demand. Biotech service providers have tried to reproduce this formula. But what if we’ve been focusing on the wrong features?

110

Jake Wintermute @synbio1.bsky.social · 11/04/2026

I will personally award the Nobel Prize in Chemistry to the first person who engineers a peptide that can do the worm

081

Jake Wintermute @synbio1.bsky.social · 11/04/2026

Hands-free lab automation solves this problem

091

Jake Wintermute @synbio1.bsky.social · 09/04/2026

We know that AI increases the value of human biological data. But by how much? Super interesting to see a specific class of human biological data assigned a spot price in a real market event

051

Jake Wintermute @synbio1.bsky.social · 08/04/2026

Lab coats should have elastic scrunchies on the sleeves

060

Jake Wintermute @synbio1.bsky.social · 06/04/2026

16 years ago I blew off my thesis research for one day to make a YouTube video about plasmids www.youtube.com/watch?v=pNeC... Today I'm in the plasmid sequencing tutorials for Plasmidsaurus www.youtube.com/watch?v=pNeC... The trick to having a fun career in science is say yes to random fun things

1121

Jake Wintermute @synbio1.bsky.social · 24/03/2026

Me when I click on an in-line citation in an online article and it takes me to the references section of the same article instead of opening the new article in a new tab

0683

Jake Wintermute @synbio1.bsky.social · 25/02/2026

We’re so blessed that evolution made the shape of eggs be the literal only possible shape for eggs that isn’t deeply unsettling

140

Jake Wintermute @synbio1.bsky.social · 24/02/2026

Biotech startups 0.0003 nanoseconds after the lab team ships a breakthrough drug to clinical trials

260

Jake Wintermute @synbio1.bsky.social · 22/02/2026

The funniest version of the future is the one where we invent ASI only to watch it immediately start culturing brain cells to invent ASSI www.cell.com/cell-reports...

060

Jake Wintermute @synbio1.bsky.social · 05/02/2026

Have fun in the small pumpkin underclass losers

150

Jake Wintermute @synbio1.bsky.social · 02/02/2026

Me and everyone who keeps calling it Pichia pastoris holding out against the attempt to rename it Komagataella phaffii

0100

Jake Wintermute @synbio1.bsky.social · 01/02/2026

How it feels to start opening tabs on a new research project

0181

Jake Wintermute @synbio1.bsky.social · 30/01/2026

There are still some good gene splicer jobs

040

Jake Wintermute @synbio1.bsky.social · 27/01/2026

The children yearn for bioproducts

120

Jake Wintermute @synbio1.bsky.social · 27/01/2026

The good version of the future includes a decentralized bioeconomy supporting lots of good green-collar jobs in bioproducts and bioservices Sourdough microbakeries hint at what that future might look like www.nytimes.com/2026/01/26/d...

080

Jake Wintermute @synbio1.bsky.social · 26/01/2026

If you had an LLM from the year 3000 and a writer's room of all the greatest communicators in history you could never invent a more worthless and confusing name for a statistical technique than "Design of Experiments"

030

Jake Wintermute @synbio1.bsky.social · 26/01/2026

The fancy popcorn from the organic market is bad at popping compared to the cheap popcorn from the normal grocery store and I’m tired of pretending it’s not

110

Jake Wintermute @synbio1.bsky.social · 21/01/2026

When you work in a yeast lab and you pause a moment to enjoy the aromas of the yeast

190

Jake Wintermute @synbio1.bsky.social · 19/01/2026

I don't want to be the main character I want to be the quest giver

150

Jake Wintermute @synbio1.bsky.social · 17/01/2026

This vintage Abcam fridge magnet does me so right It’s odd, it’s playful, it’s memorable. But what I like best is the way you can tell if reflects a real human’s sense of humor. It wasn’t designed by committee. More marketing like this please biotech companies

020

Jake Wintermute @synbio1.bsky.social · 16/01/2026

But there's nothing like the warm sound of an orbital shaker

2110

Jake Wintermute @synbio1.bsky.social · 14/01/2026

My son's school has scheduled the dungeons and dragons club, the chess club and the programming club all at the same time and I'm just trying to figure out how this could have happened

2381

Jake Wintermute @synbio1.bsky.social · 12/01/2026

This is the strongest argument in favor of automated labs

151

Jake Wintermute @synbio1.bsky.social · 11/01/2026

I've often daydreamed about fantastically large fruits and vegetables, living in a pumpkin house, boats made of watermelons, things of that nature But maybe I need to re-imagine that future because these large carrots are actually quite unsettling

2100

Jake Wintermute @synbio1.bsky.social · 09/01/2026

At first I thought this picture was just somebody from woodgang hornyposting so imagine my delight to see bark-dwelling microbes on the cover of science magazine www.science.org/doi/10.1126/...

040

Jake Wintermute @synbio1.bsky.social · 08/01/2026

Scientists often assume that "the public" has an innate and knee-jerk opposition to GMOs, lab-grown meat or other novel bioproducts But when you make something people really want it turns out they have a higher weirdness tolerance than you might expect

250

Jake Wintermute @synbio1.bsky.social · 08/01/2026

This is how I feel about attempts to build a virtual cell model

0292

Jake Wintermute @synbio1.bsky.social · 06/01/2026

Writing your lover a note on paper made from your own hair is the kind of high-upside romantic bet you can only make with a bio-based product

021