Promise and pitfalls of using large biobanks to study impacts of archaic protein-coding variants in living humans.

Human Technopole’s research is based on a mix of fundamental and translational research. We will host extensive core expertise in basic research in areas relevant for the understanding of human biolog...

Makwana, Tilley et al. generate human stem cell-based trunk-like structures approximating Carnegie stage 13–14 of development. They use them to model and study the development of the thoracic and lumbar trunk.

Applications are invited for a University Assistant/Associate Professorship in the broad area of Control Theory and Systems Biology. The successful candidate will join the Control Group

Inge et al. show that human endoderm originates from two converging developmental routes with distinct dynamics and efficiencies yet similar developmental potential. Combinatorial activin and BMP4 sig...

Topics The following will be covered extensively during lectures, exercises, and project work: Image denoising and restoration (fully supervised and self-supervised) Image translation (e.g.,

An analysis of cell-type diversity in brain samples from a variety of mammalian species, both during development and in adult animals, reveals that the TAC3 initial class of striatal interneurons is c...

Faculty studying mechanisms underlying normal nervous system function and/or how these mechanisms and interactions are affected by disease or injury

We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.

We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.

Computational methods and artificial intelligence on large-scale molecular data are transforming the study of biological systems and processes, ranging from molecular structures and cellular processes...

Research Associate: Human Lung Disease Mechanisms (Fixed Term) in the Gurdon Institute at the University of Cambridge.

View our career opportunities with Lieber Institute for Brain Development including investigators, medical research jobs, scientists, & lab techs

Yim et al. use single-cell transcriptomics to elucidate the molecular outcomes of Chd8 haploinsufficiency in the mouse cortex. Their results provide insight into dynamic, cell-type-biased transcriptio...

Nature - Using SCN2A haploinsufficiency as a proof-of-concept, upregulation of the existing functional gene copy through CRISPR activation was able to rescue neurological-associated phenotypes in...

Following Fate - Biomedical pictures for September 2025.

Inge et al. show that human endoderm originates from two converging developmental routes with distinct dynamics and efficiencies yet similar developmental potential. Combinatorial activin and BMP4 sig...

Developmental processes display temporal differences across species, leading to divergence in organ size and composition. In the cerebral cortex, neurons of diverse identities are generated sequential...

Dresden research team develops novel imaging approach to visualize individual lipids in cells and uncovers the main transport mechanism for lipids within the cell.

Medina-Cano et al. report a new protocol for the reproducible generation of cerebral cortical organoids from mouse epiblast stem cells, which recapitulate the developmental tempo, cytoarchitecture, an...