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Pierre Vanderhaeghen

@vanderhaeghenp2.bsky.social
1.7K followers 565 following 29 posts

Neuroscientist at VIB KULeuven

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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 25/08/2026
Mark your calendar: Oct 6-7 2027 the first VIB conference on neurodevelopment and neuropsychiatry in beautiful Leuven, Belgium. Amazing line-up of speakers check below - in partnership with Cell Press - www.vibconferences.be/events/new-h...
vibconferences.be
New horizons in neurodevelopment and neuropsychiatry
6-7 October 2027, Leuven, Belgium
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 14/08/2026
Human-specific genes in glia promote neoteny- beautiful work by @franckp.bsky.social and colleagues. www.cell.com/neuron/fullt...
cell.com
Human-specific SRGAP2 paralogs synchronize neotenic microglial maturation and synaptic development
Using a combination of microglia-specific conditional mouse knockout and knockin approaches and xenotransplantation of human iPSC-derived microglia, Diaz-Salazar et al. demonstrate that the human-spec...
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 14/08/2026
Beautiful study by Ikuo Suzuki lab on the impact of species-specific tempo of neurogenesis. link.springer.com/article/10.1...
link.springer.com
Interspecific diversity in the neuronal composition of the mammalian cortex arises from heterochrony in neurogenesis - The EMBO Journal
Mammals share a laminar cerebral cortex, with excitatory neuron subtypes organized in distinct layers. Although this framework is conserved, subtype balance varies markedly between species due to larg...
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Maria Antonietta Tosches @matosches.bsky.social · 27/07/2026
Excited to share a new preprint from the lab, by @andrewmatheson.bsky.social and team, where we dive into the superpower of newts: plasticity! www.biorxiv.org/content/10.6... Like many good projects, this started with a serendipitous observation... 🧵1/5
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Catherine Dulac @dulaclab.bsky.social · 13/07/2026
Amazing video on non-mammalian paternal behavior
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Daniel Colón-Ramos @dacolon.bsky.social · 12/07/2026
Help me speed the word! One of favorite conferences, taking place in Sept. Abstracts open until July21st! At a moment when science and scientific institutions are under attack, gathering as a community to share results, exchange ideas and reaffirm the value of scientific inquiry more imp than ever
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 26/06/2026
Very insipring work from Magdalena Gotz lab - Nuclear proteome reveals microtubule-associated protein regulating fate and disease: Cell www.cell.com/cell/fulltex...
cell.com
Nuclear proteome reveals microtubule-associated protein regulating fate and disease
Nuclear and cytoplasmic proteomics uncover a nuclear pool of cytoskeletal proteins, including MAP1B, whose shuttling to the nucleus increases BRG1/BAF chromatin association and regulates brain develop...
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 20/06/2026
Last days before registration and abstract submission! Come join us in beautiful Leuven in the Fall for an amazing meeting on Synapse development and function!
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 20/06/2026
thank you @blibep.bsky.social Baptiste ! And thank you so much for your fantastic work with us!
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James Briscoe @jamesbriscoe.bsky.social · 19/06/2026
In our latest editorial @amjeve.uk & I take on the dreaded impact factor Like Monday mornings no one likes them but you can't ignore them & they keep coming around However there are things we should all do as authors, reviewers & editors journals.biologists.com/dev/article/...
journals.biologists.com
The elephant in the room: impact factor
Summary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ...
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Molly Przeworski @mollyprz.bsky.social · 09/06/2026
Now published: journals.plos.org/plosbiology/...
journals.plos.org
What sets the mutation rate of a cell type in an animal species?
Mutation rates per generation are strikingly similar across germlines of animals and across at least one somatic cell type, suggesting a key role for natural selection in shaping mutation rates. This ...
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 09/06/2026
We are excited to announce the 10th edition of the European Synapse Meeting #EUSYN2026, in Leuven from October 21-23, 2026. Abstract submission closes on June 23rd! www.vibconferences.be/events/europ...
vibconferences.be
European Synapse Meeting 2026
21-23 October 2026, Leuven, Belgium Supported by VIB Training & Conferences
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Lopez-Bendito Lab @glb-lab.bsky.social · 13/05/2026
Get ready for #SPONT26! 🚀 Our official website is up and running. Check out the program and join us for the latest on spontaneous brain activity. spont2026.umin.ne.jp @guillelbendito.bsky.social
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 05/05/2026
Nice findings on the evolution of cortical cells. Evolutionary origins and transcriptomic innovations of vertebrate Cajal-Retzius cells: Current Biology www.cell.com/current-biol...
cell.com
Evolutionary origins and transcriptomic innovations of vertebrate Cajal-Retzius cells
Gumnit et al. reveal that Cajal-Retzius cells are ancestral to jawed vertebrates. Cajal-Retzius cells share a core transcription factor identity and are evolutionarily related to a population of olfac...
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 22/04/2026
Please read open letter and consider to share & sign - ERC matters! - see below
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Stein Aerts @steinaerts.bsky.social · 09/04/2026
We launched a new Group Leader vacancy in our Center for AI & Computational Biology - VIB.AI @vibai.bsky.social - with a Professorship at Ghent University. Join us with your most creative AI+Biology research plan! Apply before 31st May vib.ai/en/group-lea...
vib.ai
Group leader vacancy
We are looking for a Group Leader in applied artificial intelligence in (bio)medical research at VIB.AI & UGent, Belgium
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allen institute @alleninstitute.org · 10/04/2026
Applications are open for the Lake Conference on Comparative and Evolutionary Neurobiology - co-hosted with Circuit Neuroscience Basel! 🗓️ Oct. 25-29, 2026 📍 Seattle, WA 🧠 All career stages welcomed. 🔗 alleninstitute.org/events/lake-conf…
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Franck Polleux @franckp.bsky.social · 13/03/2026
very exciting meeting !👇
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 13/03/2026
EuroSynapse 2026 This Fall in Leuven with Eunjoon Kim Nathalie Rochefort Bea Rico Ed Lein @franckp.bsky.social @cecilecharrier.bsky.social @bellonec.bsky.social @blibep.bsky.social @fekrijeselimi.bsky.social @fan-liu.bsky.social @pouchelon.bsky.social and more! www.vibconferences.be/events/europ...
vibconferences.be
European Synapse Meeting 2026
21-23 October 2026, Leuven, Belgium Supported by VIB Training & Conferences
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Esther Klingler @estherkli.bsky.social · 12/03/2026
📣 Registrations are open for the next European Synapse Meeting, taking place in Leuven from 21–23 October 2026! With @synapse-lab.bsky.social, @vanderhaeghenp2.bsky.social, LynetteLim and MarinkaBrouwer, we’ve put together an exciting program—take a look here: www.vibconferences.be/events/europ...
vibconferences.be
European Synapse Meeting 2026
21-23 October 2026, Leuven, Belgium Supported by VIB Training & Conferences
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 10/03/2026
Should go without saying, but saying so becomes urgent: New approach methodologies: Don’t throw the baby out with the bathwater: Cell Metabolism www.cell.com/cell-metabol...
cell.com
New approach methodologies: Don’t throw the baby out with the bathwater
The NIH has recently called for expanding use of new approach methodologies (NAMs) to reduce use of animals in research. Arany discusses the need not to forget the irreplaceable aspects of animal rese...
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Carl Zimmer @carlzimmer.com · 18/02/2026
Scientists have seen Asgard archaea crawling for the first time. When it comes to the origin of eukaryotes, this is like seeing a feathered dinosaur in the wild. (Video courtesy of Philipp Ralder)
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 17/02/2026
www.thetransmitter.org/animal-model...
thetransmitter.org
Neuroscience has a species problem
If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle.
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Zebrafish Rock! @zebrafishrock.bsky.social · 16/02/2026
Published 30 years ago, 'The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio' by the Nüsslein-Volhard Lab highlighted the arduous work that took place during 'The Big Screen'. In total, 1163 mutants were described. #ZebrafishFunFacts 🧪
Cover of the December 1996 issue of Development that describes the results of The Big Screen.
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EMBO @embo.org · 11/02/2026
Happy International Day of Women and Girls in Science! 🧪 Don't forget to send in your nominations for the FEBS | EMBO #WomenInScience Award. Deadline: 15 May Read more: www.embo.org/the-embo-communities/f… #award
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olyrix.bsky.social @olyrix.bsky.social · 14/01/2026
Décès de Jean Rossier, Président passionné de Parole et Musique : www.olyrix.com/articles/act...
olyrix.com
Décès de Jean Rossier, Président passionné de Parole et Musique
L’actualité de l’opéra : Décès de Jean Rossier, Président passionné de Parole et Musique
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James Briscoe @jamesbriscoe.bsky.social · 13/01/2026
There's still time to apply to be a 2026 @dev-journal.bsky.social Pathway to Independence fellow For those about to apply for their first independent academic position, the programme offers - mentoring - leadership training - profile rising - networking journals.biologists.com/dev/pages/pi...
journals.biologists.com
Pathway to Independence programme | Development | The Company of Biologists
Pathway to Independence programme | Development | The Company of Biologists Development's Pathway to Independence programme Launched in 2022, Development’s Pathway Independence programm...
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 13/01/2026
Book the dates Oct 21-23 2026 of upcoming exciting eurosynapse meeting in Leuven! www.vibconferences.be/events/europ...
vibconferences.be
European Synapse Meeting 2026
21-23 October 2026, Leuven, Belgium Supported by VIB Training & Conferences
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Lake Conferences @lakeconferences.bsky.social · 05/01/2026
Join us this May to explore the biological mechanisms of mental health challenges and treatment strategies. Apply by January 31: lakeconferences.org
lakeconferences.org
Home - Lake Conferences
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VIB-KU Leuven Center for Neuroscience @vibneuroleuven.bsky.social · 07/01/2026
🎉 Proud moment for our Center Pierre Vanderhaeghen received the 2025 Fyssen Foundation International Prize, also awarded this year to Franck Polleux (@columbiauniversity.bsky.social) for work on the neurobiological foundations of human cognition. 🧠🏆 Congratulations! #FyssenPrize #Neuroscience #VIB
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Franck Polleux @franckp.bsky.social · 18/12/2025
Delighted to be awarded the 2025 International Prize from the @fondationfyssen.bsky.social jointly with my long time collaborator @vanderhaeghenp2.bsky.social for our work on the 'Neurobiological foundations of human cognition': www.fondationfyssen.fr/deux-laureat...
fondationfyssen.fr
Prix international 2025 - International Prize 2025 - fyssen
Deux lauréats pour le Prix international de la Fondation Fyssen La Fondation Fyssen a le plaisir d’annoncer que le Prix international est exceptionnellement attribué à deux lauréats cette année. Le pr...
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Fondation Fyssen @fondationfyssen.bsky.social · 18/12/2025
La Fondation Fyssen a le plaisir d’annoncer que le Prix international 2025, consacré au thème « Fondements neurobiologiques de la cognition humaine », est attribué à Franck Polleux et Pierre Vanderhaeghen. @franckp.bsky.social @vanderhaeghenp2.bsky.social Rdv en juin 2026 pour la remise de prix !
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 27/11/2025
Please check out and RT this new position for an exciting collaborative project with @boninlab.bsky.social and @franckp.bsky.social on the links between human-specific mechanisms and neurodevelopmental disorders in cortical circuits.
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Vincent Bonin @boninlab.bsky.social · 25/11/2025
Please repost widely. @vanderhaeghenp2.bsky.social and I are hiring a postdoc with expertise in sensory physiology and in vivo circuit imaging/manipulation. The project centers on human-specific brain development and SYNGAP1-related disorders. Call closing soon—apply ASAP jobs.vib.be/j/119852/pos...
jobs.vib.be
Postdoctoral Fellow / PhD Student in Systems Neuroscience - VIB
The Laboratory of Cortical Information Processing | Vision to Action at NERF (www.nerf.be) invites applications for a Postdoctoral Fellow or PhD Student to work on a new research project funded by the...
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 26/10/2025
Nice cover of our work linking SRGAP2/SYNGAP1 synaptic neoteny and ID/ASD with @blibep.bsky.social @benvermaercke.bsky.social @franckp.bsky.social @boninlab.bsky.social @cecilecharrier.bsky.social www.thetransmitter.org/spectrum/pro...
thetransmitter.org
Protein tug-of-war controls pace of synaptic development, sets human brains apart
Human-specific duplicates of SRGAP2 prolong cortical development by manipulating SYNGAP, an autism-linked protein that slows synaptic growth.
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James Briscoe @jamesbriscoe.bsky.social · 07/10/2025
Very sad news, John Gurdon has died. A developmental biologist's developmental biologist, Nobel prize winner His work is the foundation of much of today's dev & stem cell bio. An inspiration to many, including me. Always asking questions & wanting the answers www.magd.cam.ac.uk/news/profess...
magd.cam.ac.uk
Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
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Noonan Lab @noonanlab.bsky.social · 23/09/2025
Out in Cell Genomics: A comprehensive analysis of the cell-type-specific effects of CHD8 loss of function on gene expression in the embryonic and juvenile mouse cortex. Thread 🧵: www.cell.com/cell-genomic...
cell.com
Cell-type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development
Yim et al. use single-cell transcriptomics to elucidate the molecular outcomes of Chd8 haploinsufficiency in the mouse cortex. Their results provide insight into dynamic, cell-type-biased transcriptio...
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 03/09/2025
New from the lab: Fatty Acid Metabolism Sets the Species-specific Tempo of Cortical Development through Protein Acetylation Dynamics. Led by amazing trio: @ryo2iwata.bsky.social , Isabel Gallego, @emirerkol.bsky.social, together with @steinaerts.bsky.social , @fendtlab.bsky.social
biorxiv.org
Species-specific Rates of Fatty Acid Metabolism Set the Scale of Temporal Patterning of Corticogenesis through Protein Acetylation Dynamics
Developmental processes display temporal differences across species, leading to divergence in organ size and composition. In the cerebral cortex, neurons of diverse identities are generated sequential...
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 31/07/2025
Beautiful and inspiring work from Gero Miesenböck and colleagues www.nature.com/articles/s41...
nature.com
Mitochondrial origins of the pressure to sleep - Nature
Research on Drosophila neurons shows links between the need to sleep and aerobic metabolism, indicating that the pressure to sleep may have a mitochondrial origin.
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Teresa Rayon @trayon.bsky.social · 07/06/2025
May has been quite the month… The #EvoDevoConference was a blast 💥 Thanks to all participants and organizers for your engagement! @mdiazcuadros.bsky.social @bassemh.bsky.social @vanderhaeghenp2.bsky.social 📸 (1/2)
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Dmitri Petrov @petrovadmitri.bsky.social · 03/06/2025
Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...
philanthropy.cam.ac.uk
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
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Bassem Hassan @bassemh.bsky.social · 07/05/2025
Hot off the press: The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience: rdcu.be/ek010
rdcu.be
Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster
Nature Neuroscience - The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in...
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 14/05/2025
wonderful - congratulations @debbysilver.bsky.social !!
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Pierre Vanderhaeghen @vanderhaeghenp2.bsky.social · 10/05/2025
Fantastic opportunity for neuroscience research. The ROGER DE SPOELBERCH Prize for a basic or clinical research project in the areas of neurodegenerative diseases or psychiatric disorders. 750.000 EUR - Deadline JUNE 30 2025. www.fondation-roger-de-spoelberch.ch/en/roger-de-...
fondation-roger-de-spoelberch.ch
ROGER DE SPOELBERCH Prize | Fondation ROGER DE SPOELBERCH
Each year, the Foundation awards the ROGER DE SPOELBERCH Prize to a laureate for a clinical or fundamental scientific research project in the field of neurodegenerative diseases and certain psychiatri...
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Pedro J. Goncalves @ppjgoncalves.bsky.social · 08/05/2025
Fantastic PhD opportunities at the intersection of machine learning and biology. Come join us at @vibai.bsky.social! More details at: vib.ai/en/vibai-int...
vib.ai
VIB.AI International PhD Call 2025
The VIB.AI International PhD Call 2025 is now open. We invite applicants from around the world to join an interdisciplinary research environment at the interface of AI, computational biology, and life...
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Angelika Harbauer @harbauerlab.bsky.social · 02/05/2025
Join us in Engelberg, Switzerland, for an exciting #EMBO workshop on #mitochondria in the nervous system #EMBOmitoNervousSys! Great speaker line up and opportunities for short talks from early career scientists. Submit your abstract until May 30st! @jcourchet.bsky.social @tatjanakleele.bsky.social
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Motori Lab @motorilab.bsky.social · 05/05/2025
I'm thrilled to be co-organizing the very first EMBO Workshop bridging mitochondria and brain research - a powerhouse of science, ideas, and amazing speakers! 🧠🔬 📅 registration closes MAY 30th, so don’t wait to snag your spot! Stay tuned - more updates about the topics and speakers coming soon! 🎙️
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Patricia Nano @prnano9.bsky.social · 02/05/2025
It’s out! The first paper from my postdoc – and first from the @bhadurilab.bsky.social – is now live @natneuro.nature.com . 🧠✨ Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
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Simon Fisher @profsimonfisher.bsky.social · 02/05/2025
Turns out eye colour (mainly a result of iris pigmentation) is yet another complex trait, now demystified by genomic advances. DNA variants in two neighbouring genes (HERC2 & OCA2) explain much of the blue-brown variation, but analyses of ~193k people in 2021 revealed another 50 genetic loci. 👇 7/n
science.org
Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color
A GWAS including 192,986 European and 1636 Asian participants identifies 50 novel discrete associations with eye color.
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